omeprazole has been researched along with Complications, Pregnancy in 16 studies
Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our purpose was to determine whether omeprazole use during pregnancy is associated with an increased risk of malformations, spontaneous abortions, decreased birth weight, or perinatal complications." | 9.08 | The safety of omeprazole during pregnancy: a multicenter prospective controlled study. ( Addis, A; Bonati, M; Koren, G; Lalkin, A; Loebstein, R; Mastroiacovo, P; Mazzone, T; Ramezani-Namin, F; Vial, T, 1998) |
| "Symptomatic gastroesophageal reflux is a common complication of pregnancy and lactation." | 5.30 | Omeprazole for refractory gastroesophageal reflux disease during pregnancy and lactation. ( Armstrong, D; Marshall, JK; Thompson, AB, 1998) |
| "We followed up 295 pregnancies exposed to omeprazole [233 in the first trimester (T1)], 62 to lansoprazole (55 in T1) and 53 to pantoprazole (47 in T1), and compared pregnancy outcome to that of 868 European Network of Teratology Information Services controls." | 5.11 | The safety of proton pump inhibitors in pregnancy: a multicentre prospective controlled study. ( Arnon, J; Clementi, M; De Santis, M; Diav-Citrin, O; Malm, H; Ornoy, A; Robert-Gnansia, E; Schaefer, C; Shechtman, S; Valti, E; van Tonningen, MR, 2005) |
| "Our purpose was to determine whether omeprazole use during pregnancy is associated with an increased risk of malformations, spontaneous abortions, decreased birth weight, or perinatal complications." | 5.08 | The safety of omeprazole during pregnancy: a multicenter prospective controlled study. ( Addis, A; Bonati, M; Koren, G; Lalkin, A; Loebstein, R; Mastroiacovo, P; Mazzone, T; Ramezani-Namin, F; Vial, T, 1998) |
| " The newest PPI, esomeprazole, brings a statistically significant increase in healing of mucosal injury and symptom relief in patients with erosive esophagitis, compared with omeprazole and lansoprazole." | 4.81 | Pharmacologic management of gastroesophageal reflux disease. ( Katz, PO; Ramakrishnan, A, 2002) |
| " Physiologic factors that may contribute to a poor response to these drugs include the considerable variation in the bioavailability of PPIs, the need to take PPIs with meals, the influence of Helicobacter pylori-associated gastritis, and genetic variation in enzyme capacity, resulting in rapid and slow metabolizers of PPIs." | 2.42 | Medical management of patients with esophageal or supraesophageal gastroesophageal reflux disease. ( Richter, JE, 2003) |
| "Proton pump inhibitors are used to treat gastroesophageal reflux, a symptom common in pregnancy." | 2.41 | Use of proton pump inhibitors during pregnancy and rates of major malformations: a meta-analysis. ( Abdollahi, M; Koren, G; Magee, LA; Moretti, ME; Nikfar, S, 2002) |
| "Gastroesophageal reflux disease (GERD) is frequently seen during pregnancy." | 1.46 | Treatment of reflux disease during pregnancy and lactation. ( Dağlı, Ü; Kalkan, İH, 2017) |
| "Symptomatic gastroesophageal reflux is a common complication of pregnancy and lactation." | 1.30 | Omeprazole for refractory gastroesophageal reflux disease during pregnancy and lactation. ( Armstrong, D; Marshall, JK; Thompson, AB, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (25.00) | 18.2507 |
| 2000's | 7 (43.75) | 29.6817 |
| 2010's | 4 (25.00) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Thélin, CS | 1 |
| Richter, JE | 2 |
| Dağlı, Ü | 1 |
| Kalkan, İH | 1 |
| Jarraya, A | 1 |
| Elleuch, S | 1 |
| Zouari, J | 1 |
| Trigui, K | 1 |
| Sofiene, A | 1 |
| Smaoui, M | 1 |
| Kolsi, K | 1 |
| Pieroni, KP | 1 |
| Bass, D | 1 |
| Malik, R | 1 |
| Guleria, K | 1 |
| Kaur, I | 1 |
| Sikka, M | 1 |
| Radhakrishnan, G | 1 |
| Nikfar, S | 1 |
| Abdollahi, M | 1 |
| Moretti, ME | 1 |
| Magee, LA | 1 |
| Koren, G | 3 |
| Weusten, BL | 1 |
| Exalto, N | 1 |
| Otten, MH | 1 |
| Diav-Citrin, O | 1 |
| Arnon, J | 1 |
| Shechtman, S | 1 |
| Schaefer, C | 1 |
| van Tonningen, MR | 1 |
| Clementi, M | 1 |
| De Santis, M | 1 |
| Robert-Gnansia, E | 1 |
| Valti, E | 1 |
| Malm, H | 1 |
| Ornoy, A | 1 |
| Lalkin, A | 2 |
| Magee, L | 1 |
| Addis, A | 2 |
| Loebstein, R | 2 |
| Marshall, JK | 1 |
| Thompson, AB | 1 |
| Armstrong, D | 1 |
| Ramezani-Namin, F | 1 |
| Mastroiacovo, P | 1 |
| Mazzone, T | 1 |
| Vial, T | 1 |
| Bonati, M | 1 |
| Ruigómez, A | 1 |
| García Rodríguez, LA | 1 |
| Cattaruzzi, C | 1 |
| Troncon, MG | 1 |
| Agostinis, L | 1 |
| Wallander, MA | 1 |
| Johansson, S | 1 |
| Wall, CA | 1 |
| Gaffney, EF | 1 |
| Mellotte, GJ | 1 |
| Ivany, JM | 1 |
| Anderson, DE | 1 |
| Ramakrishnan, A | 1 |
| Katz, PO | 1 |
5 reviews available for omeprazole and Complications, Pregnancy
| Article | Year |
|---|---|
Review article: the management of heartburn during pregnancy and lactation.
Topics: Alginates; Antacids; Breast Feeding; Contraindications, Drug; Female; Gastroesophageal Reflux; Gastr | 2020 |
Use of proton pump inhibitors during pregnancy and rates of major malformations: a meta-analysis.
Topics: Abnormalities, Drug-Induced; Female; Fetus; Gastroesophageal Reflux; Humans; Maternal-Fetal Exchange | 2002 |
Medical management of patients with esophageal or supraesophageal gastroesophageal reflux disease.
Topics: Age Factors; Barrett Esophagus; Female; Gastric Acid; Gastritis; Gastroesophageal Reflux; Gastrointe | 2003 |
[Drug treatment of gastro-esophageal reflux disease in pregnant women: consensus guidelines of gastroenterologists and gynaecologists].
Topics: Adult; Anti-Ulcer Agents; Female; Gastroenterology; Gastroesophageal Reflux; Gynecology; Humans; Ome | 2003 |
Pharmacologic management of gastroesophageal reflux disease.
Topics: Barrett Esophagus; Esomeprazole; Esophagitis; Female; Gastroesophageal Reflux; Humans; Omeprazole; P | 2002 |
3 trials available for omeprazole and Complications, Pregnancy
| Article | Year |
|---|---|
Effect of Helicobacter pylori eradication therapy in iron deficiency anaemia of pregnancy - a pilot study.
Topics: Adolescent; Adult; Amoxicillin; Anemia, Iron-Deficiency; Anti-Bacterial Agents; Clarithromycin; Dise | 2011 |
The safety of proton pump inhibitors in pregnancy: a multicentre prospective controlled study.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abnormalities, Drug-Induced; Adult; Anti-Ulcer Agents; Benz | 2005 |
The safety of omeprazole during pregnancy: a multicenter prospective controlled study.
Topics: Abnormalities, Drug-Induced; Adult; Birth Weight; Delivery, Obstetric; Enzyme Inhibitors; Female; Ga | 1998 |
8 other studies available for omeprazole and Complications, Pregnancy
| Article | Year |
|---|---|
Treatment of reflux disease during pregnancy and lactation.
Topics: Alginates; Antacids; Female; Gastroesophageal Reflux; Glucuronic Acid; Hexuronic Acids; Humans; Lact | 2017 |
[Hyperemesis gravidarum with severe electrolyte disorders: report of a case].
Topics: Acute Kidney Injury; Antiemetics; Female; Fluid Therapy; Hepatomegaly; Humans; Hyperemesis Gravidaru | 2015 |
Proton pump inhibitor treatment for congenital chloride diarrhea.
Topics: Adult; Amniotic Fluid; Betamethasone; Chloride-Bicarbonate Antiporters; Delivery, Obstetric; Diarrhe | 2011 |
Acid-suppressing drugs during pregnancy.
Topics: Abnormalities, Drug-Induced; Anti-Ulcer Agents; Cohort Studies; Female; Fetus; Gastroesophageal Refl | 1997 |
Omeprazole for refractory gastroesophageal reflux disease during pregnancy and lactation.
Topics: Adult; Female; Gastroesophageal Reflux; Histamine H2 Antagonists; Humans; Lactation; Milk, Human; Om | 1998 |
Use of cimetidine, omeprazole, and ranitidine in pregnant women and pregnancy outcomes.
Topics: Abnormalities, Drug-Induced; Anti-Ulcer Agents; Cimetidine; Cohort Studies; Female; Humans; Infant, | 1999 |
Hypercalcaemia and acute interstitial nephritis associated with omeprazole therapy.
Topics: Acute Disease; Adult; Anti-Inflammatory Agents; Female; Humans; Hypercalcemia; Nephritis, Interstiti | 2000 |
Propylene glycol toxicosis in a llama.
Topics: 3-Hydroxybutyric Acid; Abdomen; Animals; Anti-Ulcer Agents; Aspartate Aminotransferases; Camelids, N | 2001 |