omeprazole has been researched along with Colonic Neoplasms in 14 studies
Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Omeprazole was prescribed but withdrawn later, and oral vancomycin was given at a dose of 0." | 1.46 | When omeprazole met with asymptomatic Clostridium difficile colonization in a postoperative colon cancer patient: A case report. ( Li, B; Liu, L; Ma, H; Wang, Z, 2017) |
| "Omeprazole treatment in human colon cancer cell lines HCT-116 and HCA-7 cells resulted in induction of p21waf1/cip1 and decreased the expression of anti-apoptotic proteins Bcl-2, Bcl-XL and survivin in a dose-dependent manner." | 1.38 | Anti-carcinogenic properties of omeprazole against human colon cancer cells and azoxymethane-induced colonic aberrant crypt foci formation in rats. ( Li, Q; Patlolla, JM; Rao, CV; Steele, VE; Zhang, Y, 2012) |
| "Omeprazole has a cytostatic effect on one of three colorectal cancer cell lines but the mechanism for this effect of omeprazole and its potential role in treatment awaits elucidation." | 1.29 | Omeprazole inhibits growth of cancer cell line of colonic origin. ( Chintalapani, S; Goo, R; Luk, G; Lundqvist, M; Maliakkal, B; Oberg, K; Reddy, J; Tobi, M, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (50.00) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Madka, V | 1 |
| Kumar, G | 1 |
| Pathuri, G | 1 |
| Panneerselvam, J | 1 |
| Zhang, Y | 2 |
| Ganta, V | 1 |
| Lightfoot, S | 1 |
| Lubet, R | 1 |
| Suen, CS | 1 |
| Steele, VE | 2 |
| Janakiram, NB | 1 |
| Mohammed, A | 1 |
| Rao, CV | 2 |
| Li, B | 1 |
| Ma, H | 1 |
| Wang, Z | 1 |
| Liu, L | 1 |
| Patlolla, JM | 1 |
| Li, Q | 1 |
| Watson, SA | 2 |
| Morris, TM | 1 |
| McWilliams, DF | 1 |
| Harris, J | 1 |
| Evans, S | 1 |
| Smith, A | 1 |
| Clarke, PA | 2 |
| Hsu, TC | 1 |
| Su, CF | 1 |
| Leu, SC | 1 |
| Huang, PC | 1 |
| Wang, TE | 1 |
| Chu, CH | 1 |
| Dickson, JH | 1 |
| Harris, JC | 1 |
| Grabowska, A | 1 |
| Hurwitz, A | 2 |
| Sztern, MI | 2 |
| Looney, GA | 2 |
| Pinson, DM | 2 |
| Bauer, KD | 1 |
| Kimler, BF | 2 |
| Tobi, M | 1 |
| Chintalapani, S | 1 |
| Goo, R | 1 |
| Maliakkal, B | 1 |
| Reddy, J | 1 |
| Lundqvist, M | 1 |
| Oberg, K | 1 |
| Luk, G | 1 |
| Havu, N | 1 |
| Mattsson, H | 1 |
| Penman, ID | 1 |
| el-Omar, E | 1 |
| McGregor, JR | 1 |
| Hillan, KJ | 1 |
| O'Dwyer, PJ | 1 |
| McColl, KE | 1 |
| Chen, D | 1 |
| Destrée, M | 1 |
| Håkanson, R | 1 |
| Willems, G | 1 |
| Raderer, M | 1 |
| Pfeffel, F | 1 |
| Pohl, G | 1 |
| Mannhalter, C | 1 |
| Valencak, J | 1 |
| Chott, A | 1 |
| Freston, JW | 1 |
| Graffner, H | 1 |
| Singh, G | 1 |
| Chaudry, I | 1 |
| Milsom, JW | 1 |
1 review available for omeprazole and Colonic Neoplasms
| Article | Year |
|---|---|
Clinical significance of hypergastrinaemia: relevance to gastrin monitoring during omeprazole therapy.
Topics: Colonic Neoplasms; Drug Monitoring; Fasting; Gastric Mucosa; Gastrins; Humans; Omeprazole; Ranitidin | 1992 |
1 trial available for omeprazole and Colonic Neoplasms
| Article | Year |
|---|---|
Omeprazole is more effective than a histamine H2-receptor blocker for maintaining a persistent elevation of gastric pH after colon resection for cancer.
Topics: Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Cimetidine; Colonic Neoplasms; Female; Gastric Ac | 2004 |
12 other studies available for omeprazole and Colonic Neoplasms
| Article | Year |
|---|---|
Proton Pump Inhibitor Omeprazole Suppresses Carcinogen-induced Colonic Adenoma Progression to Adenocarcinoma in F344 Rat.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Omeprazole; Proton P | 2021 |
When omeprazole met with asymptomatic Clostridium difficile colonization in a postoperative colon cancer patient: A case report.
Topics: Aged, 80 and over; Clostridium Infections; Colonic Neoplasms; Diagnosis, Differential; Humans; Injec | 2017 |
Anti-carcinogenic properties of omeprazole against human colon cancer cells and azoxymethane-induced colonic aberrant crypt foci formation in rats.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Cell Growth Processes; Colonic Neoplasms; | 2012 |
Potential role of endocrine gastrin in the colonic adenoma carcinoma sequence.
Topics: Adenocarcinoma; Adenoma; Animals; Colonic Neoplasms; Computer Systems; Enzyme Inhibitors; Female; Fi | 2002 |
Gastrin enhances the angiogenic potential of endothelial cells via modulation of heparin-binding epidermal-like growth factor.
Topics: Animals; Cell Differentiation; Chick Embryo; Colonic Neoplasms; Endothelial Cells; Epidermal Growth | 2006 |
Effects of omeprazole on cell kinetics of carcinogen-induced colon tumours in rats.
Topics: Animals; Anti-Ulcer Agents; Carcinogens; Cell Cycle; Colonic Neoplasms; DNA Replication; Gastric Muc | 1995 |
Omeprazole inhibits growth of cancer cell line of colonic origin.
Topics: Cell Division; Cell Line; Colonic Neoplasms; Colorectal Neoplasms; Gastrins; Humans; Omeprazole; Tum | 1995 |
Drug-induced hypergastrinemia: absence of trophic effects on colonic carcinoma in rats.
Topics: Analysis of Variance; Animals; Colonic Neoplasms; Gastrins; Intestinal Mucosa; Male; Methylazoxymeth | 1995 |
Omeprazole inhibits colorectal carcinogenesis induced by azoxymethane in rats.
Topics: Animals; Azoxymethane; Body Weight; Colonic Neoplasms; Eating; Female; Gastrins; Omeprazole; Rats; R | 1993 |
Endogenous hypergastrinaemia does not promote growth of colonic mucosa or of a transplanted colon adenocarcinoma in rats.
Topics: Adenocarcinoma; Animals; Cell Division; Colon; Colonic Neoplasms; Enzyme Inhibitors; Gastrins; Intes | 1998 |
Regression of colonic low grade B cell lymphoma of the mucosa associated lymphoid tissue type after eradication of Helicobacter pylori.
Topics: Aged; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Colonic Neoplasms; Drug Therapy, Com | 2000 |
Omeprazole-induced hypergastrinemia does not influence growth of colon carcinoma.
Topics: Adenocarcinoma; Animals; Cell Division; Colonic Neoplasms; Gastrins; Liver Neoplasms; Mice; Mice, In | 1992 |