omeprazole has been researched along with Clinically Isolated CNS Demyelinating Syndrome in 1 studies
Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Omeprazole treatment (10 mg/kg) for 2 weeks significantly improved the impaired motor coordinative function of demyelinated mice, increased the expression of myelin basic protein (MBP) and up-regulated the expression of genes related to remyelination." | 1.51 | Repurposing of omeprazole for oligodendrocyte differentiation and remyelination. ( Harris, RA; Kang, Z; Sun, J; Wang, J; Wang, Y; Wu, G; Wu, X; Zhu, K; Zou, Z, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhu, K | 1 |
| Sun, J | 1 |
| Kang, Z | 1 |
| Zou, Z | 1 |
| Wu, X | 1 |
| Wang, Y | 1 |
| Wu, G | 1 |
| Harris, RA | 1 |
| Wang, J | 1 |
1 other study available for omeprazole and Clinically Isolated CNS Demyelinating Syndrome
| Article | Year |
|---|---|
Repurposing of omeprazole for oligodendrocyte differentiation and remyelination.
Topics: Animals; Axons; Cell Differentiation; Cuprizone; Demyelinating Diseases; Drug Repositioning; Male; M | 2019 |