omeprazole has been researched along with Chronic Illness in 152 studies
Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Out of 45 patients referred for unexplained chronic persistent cough, 36 had at least one of the GI investigations (endoscopy, 24-h esophageal pH-metry and a 4-week trial of proton pump inhibitor (PPI) therapy) positive and were randomly assigned to receive either 30 mg lansoprazole o." | 9.12 | Proton pump inhibitor treatment of patients with gastroesophageal reflux-related chronic cough: a comparison between two different daily doses of lansoprazole. ( Baldi, F; Cappiello, R; Cavoli, C; Ghersi, S; Roda, E; Torresan, F, 2006) |
| " This prospective randomised study aimed to investigate whether H pylori eradication can influence gastritis and its sequelae during long term omeprazole therapy for gastro-oesophageal reflux disease (GORD)." | 9.11 | Cure of Helicobacter pylori infection in patients with reflux oesophagitis treated with long term omeprazole reverses gastritis without exacerbation of reflux disease: results of a randomised controlled trial. ( Dent, J; Festen, HP; Goldfain, D; Havu, N; Klinkenberg-Knol, EC; Kolkman, JJ; Kuipers, EJ; Lamm, M; Nelis, GF; Snel, P; Walan, A; Zeitoun, P, 2004) |
| "Patients diagnosed with idiopathic chronic laryngitis were randomized to receive either lansoprazole 30 mg p." | 9.09 | Lansoprazole treatment of patients with chronic idiopathic laryngitis: a placebo-controlled trial. ( Buchner, A; El-Serag, HB; Gavin, M; Inadomi, JM; Lee, P; McCarthy, DM, 2001) |
| "In this randomized multicentre study, 267 duodenal ulcer patients were treated for 2 weeks with omeprazole 40 bid (Group A) or 20 mg bid (Group B), respectively, and with amoxycillin 0." | 9.08 | Dual therapy with high or low doses of omeprazole does not achieve an acceptable rate of Helicobacter pylori eradication in duodenal ulcer patients. A multicentre randomized long-term detailed study. ( Annibale, B; Bordi, C; Cesana, B; Damilano, I; Franceschi, M; Maconi, G; Pilato, FP, 1997) |
| "This study set out to investigate the effects of omeprazole or ranitidine on the progression of antral gastritis and Helicobacter pylori in patients with active duodenal ulcer." | 9.07 | Effect of omeprazole on duodenal ulcer-associated antral gastritis and Helicobacter pylori. ( Branicki, FJ; Ho, J; Hui, WM; Lai, CL; Lam, SK; Lau, WY; Lok, AS; Ng, MM, 1991) |
| "Our aims were to describe clinical characteristics of patients with chronic posterior laryngitis and to predict the response to omeprazole therapy." | 7.72 | Manifestations of gastroesophageal reflux and response to omeprazole therapy in patients with chronic posterior laryngitis: an evaluation based on clinical practice. ( Bastida, G; Bau, I; Garrigues, V; Gisbert, L; Nos, P; Ortiz, V; Ponce, J, 2003) |
| "To evaluate the efficacy of one-week therapy with omeprazole, clarithromycin and amoxycillin in eradicating Helicobacter pylori and healing duodenal ulcer." | 7.69 | [One-week treatment with omeprazole, clarithromycin and amoxicillin: high efficacy in the eradication of Helicobacter pylori and cicatrization of duodenal ulcer]. ( Abraira, V; Alvarez Baleriola, I; Boixeda, D; Ceña, G; García Plaza, A; Gisbert, JP; Martín de Argila, C; Mur, M, 1997) |
| "Evolution of gastrinoma tumoral mass, fasting serum gastrin concentrations, and gastric endocrine cells has been analyzed in 21 patients with the Zollinger-Ellison syndrome committed to long-term omeprazole treatment (up to 7." | 7.68 | Gastric endocrine cell evolution in patients with Zollinger-Ellison syndrome. Influence of gastrinoma growth and long-term omeprazole treatment. ( Bonfils, S; Cadiot, G; Lehy, T; Mignon, M; Ruszniewski, P, 1993) |
| "The effect of a proton pump inhibitor, omeprazole (OPZ), in combination with mouse epidermal growth factor (EGF), on the healing of chronic gastric ulcers induced by acetic acid in submandibular glands removed rats (SMR rat) was investigated." | 7.68 | [Effect of proton pump inhibitor, in combination with epidermal growth factor, on the healing of chronic gastric ulcer in submandibular gland removed rats]. ( Imai, S; Itoh, M; Joh, T; Takeuchi, T; Yokoyama, Y, 1992) |
| "Penetrated cysteamine-induced duodenal ulcers in rats have a very prolonged course of healing." | 7.67 | Effect of antisecretory agents and vagotomy on healing of "chronic" cysteamine-induced duodenal ulcers in rats. ( Kirkegaard, P; Poulsen, SS; Raaberg, L; Skov Olsen, P; Therkelsen, K, 1986) |
| "Twenty-three patients were evaluated for gastroesophageal reflux disease; six (26%) were eventually determined to have an acid-related cough." | 6.69 | A prospective evaluation of esophageal testing and a double-blind, randomized study of omeprazole in a diagnostic and therapeutic algorithm for chronic cough. ( Kavuru, MS; Ours, TM; Richter, JE; Schilz, RJ, 1999) |
| "Omeprazole has been shown to have a good long-term safety profile, as evaluated in these trials." | 6.39 | Long-term treatment of gastro-oesophageal reflux disease with omeprazole. ( Lundell, L, 1994) |
| "Patients with moderate to severe chronic plaque psoriasis (n = 21) received single oral doses of sensitive probe substrates for CYP1A2 (caffeine 100 mg), CYP2C9 (warfarin 10 mg), CYP2C19 (omeprazole 20 mg), CYP2D6 (metoprolol 50 mg), and CYP3A (midazolam 2 mg) on day 1, followed by 12 weeks of subcutaneous risankizumab treatment of 150 mg once every 4 weeks from day 8 to day 92, and again the same cocktail of substrates on day 98." | 5.30 | Lack of Effect of 12-Week Treatment with Risankizumab on the Pharmacokinetics of Cytochrome P450 Probe Substrates in Patients with Moderate to Severe Chronic Plaque Psoriasis. ( Camez, A; Cheng, L; Ignatenko, S; Khatri, A; Othman, AA; Pang, Y, 2019) |
| "To compare, during strong acid inhibition with omeprazole, the effect of 2 different doses of an enteric-coated pancreatic enzyme preparation on fecal fat excretion and abdominal symptoms in patients with exocrine insufficiency due to chronic pancreatitis (CP)." | 5.12 | Efficacy of lower than standard doses of pancreatic enzyme supplementation therapy during acid inhibition in patients with pancreatic exocrine insufficiency. ( Lamers, CB; Masclee, AA; Symersky, T; Vecht, J, 2006) |
| "Out of 45 patients referred for unexplained chronic persistent cough, 36 had at least one of the GI investigations (endoscopy, 24-h esophageal pH-metry and a 4-week trial of proton pump inhibitor (PPI) therapy) positive and were randomly assigned to receive either 30 mg lansoprazole o." | 5.12 | Proton pump inhibitor treatment of patients with gastroesophageal reflux-related chronic cough: a comparison between two different daily doses of lansoprazole. ( Baldi, F; Cappiello, R; Cavoli, C; Ghersi, S; Roda, E; Torresan, F, 2006) |
| " This prospective randomised study aimed to investigate whether H pylori eradication can influence gastritis and its sequelae during long term omeprazole therapy for gastro-oesophageal reflux disease (GORD)." | 5.11 | Cure of Helicobacter pylori infection in patients with reflux oesophagitis treated with long term omeprazole reverses gastritis without exacerbation of reflux disease: results of a randomised controlled trial. ( Dent, J; Festen, HP; Goldfain, D; Havu, N; Klinkenberg-Knol, EC; Kolkman, JJ; Kuipers, EJ; Lamm, M; Nelis, GF; Snel, P; Walan, A; Zeitoun, P, 2004) |
| " MATERIAL OG METHODS: Fifteen healthy subjects and seven patients with chronic pancreatitis were entered in a randomised, double-blind, cross-over study of the exocrine pancreatic function after placebo or omeprazole 80 mg daily for three days." | 5.10 | [Does intake of gastric acid pump inhibitor affect the evaluation of the Lundh test?]. ( Damborg, F; Damborg, SB; Schaffalitzky de Muckadell, OB, 2002) |
| " pylori-infected patients with nonulcer dyspepsia to receive twice-daily treatment with 20 mg of omeprazole, 1000 mg of amoxicillin, and 500 mg of clarithromycin for 14 days and 167 such patients to receive identical-appearing placebos; all patients were then followed through regular visits for 12 months." | 5.09 | Absence of benefit of eradicating Helicobacter pylori in patients with nonulcer dyspepsia. ( Ballard, ED; Fennerty, MB; Talley, NJ; Vakil, N, 1999) |
| "Five patients with gastroesophageal reflux disease (GERD), who also had chronic functional diarrhea and postprandial urgency, unexpectedly noted rapid relief of their diarrhea and urgency when they took lansoprazole for their heartburn." | 5.09 | Inhibition of gastric secretion relieves diarrhea and postprandial urgency associated with irritable bowel syndrome or functional diarrhea. ( Dave, B; Rubin, W, 1999) |
| "Patients diagnosed with idiopathic chronic laryngitis were randomized to receive either lansoprazole 30 mg p." | 5.09 | Lansoprazole treatment of patients with chronic idiopathic laryngitis: a placebo-controlled trial. ( Buchner, A; El-Serag, HB; Gavin, M; Inadomi, JM; Lee, P; McCarthy, DM, 2001) |
| "Omeprazole is well tolerated, highly effective, and safe for treatment of erosive esophagitis and symptoms of gastroesophageal reflux in children, including children in whom antireflux surgery or other medical therapy has failed." | 5.09 | Omeprazole for treatment of chronic erosive esophagitis in children: a multicenter study of efficacy, safety, tolerability and dose requirements. International Pediatric Omeprazole Study Group. ( Dalväg, A; Hassall, E; Israel, D; Junghard, O; Lundborg, P; Radke, M; Shepherd, R; Sköld, B, 2000) |
| "In this randomized multicentre study, 267 duodenal ulcer patients were treated for 2 weeks with omeprazole 40 bid (Group A) or 20 mg bid (Group B), respectively, and with amoxycillin 0." | 5.08 | Dual therapy with high or low doses of omeprazole does not achieve an acceptable rate of Helicobacter pylori eradication in duodenal ulcer patients. A multicentre randomized long-term detailed study. ( Annibale, B; Bordi, C; Cesana, B; Damilano, I; Franceschi, M; Maconi, G; Pilato, FP, 1997) |
| "In order to investigate whether chronic duodenal ulcer disease is a consequence of disturbed mucosal turnover and growth factor expression, we studied 16 patients with duodenal ulcers before, during, and after endoscopic healing with lansoprazole or sucralfate." | 5.08 | Effect of chronic duodenal ulceration and its treatment with lanzoprazole or sucralfate on gastroduodenal mucosal protein turnover and TGF-alpha, bFGF, and EGF receptor expression in humans. ( Marks, IN; O'Keefe, SJ; Ogden, J; Winter, T; Zhang, T, 1998) |
| "This study set out to investigate the effects of omeprazole or ranitidine on the progression of antral gastritis and Helicobacter pylori in patients with active duodenal ulcer." | 5.07 | Effect of omeprazole on duodenal ulcer-associated antral gastritis and Helicobacter pylori. ( Branicki, FJ; Ho, J; Hui, WM; Lai, CL; Lam, SK; Lau, WY; Lok, AS; Ng, MM, 1991) |
| "Findings will provide timely information on the safety, efficacy, and optimal dosing of t-PA to treat moderate/severe COVID-19-induced ARDS, which can be rapidly adapted to a phase III trial (NCT04357730; FDA IND 149634)." | 4.21 | ( Abbasi, S; Abd El-Wahab, A; Abdallah, M; Abebe, G; Aca-Aca, G; Adama, S; Adefegha, SA; Adidigue-Ndiome, R; Adiseshaiah, P; Adrario, E; Aghajanian, C; Agnese, W; Ahmad, A; Ahmad, I; Ahmed, MFE; Akcay, OF; Akinmoladun, AC; Akutagawa, T; Alakavuklar, MA; Álava-Rabasa, S; Albaladejo-Florín, MJ; Alexandra, AJE; Alfawares, R; Alferiev, IS; Alghamdi, HS; Ali, I; Allard, B; Allen, JD; Almada, E; Alobaid, A; Alonso, GL; Alqahtani, YS; Alqarawi, W; Alsaleh, H; Alyami, BA; Amaral, BPD; Amaro, JT; Amin, SAW; Amodio, E; Amoo, ZA; Andia Biraro, I; Angiolella, L; Anheyer, D; Anlay, DZ; Annex, BH; Antonio-Aguirre, B; Apple, S; Arbuznikov, AV; Arinsoy, T; Armstrong, DK; Ash, S; Aslam, M; Asrie, F; Astur, DC; Atzrodt, J; Au, DW; Aucoin, M; Auerbach, EJ; Azarian, S; Ba, D; Bai, Z; Baisch, PRM; Balkissou, AD; Baltzopoulos, V; Banaszewski, M; Banerjee, S; Bao, Y; Baradwan, A; Barandika, JF; Barger, PM; Barion, MRL; Barrett, CD; Basudan, AM; Baur, LE; Baz-Rodríguez, SA; Beamer, P; Beaulant, A; Becker, DF; Beckers, C; Bedel, J; Bedlack, R; Bermúdez de Castro, JM; Berry, JD; Berthier, C; Bhattacharya, D; Biadgo, B; Bianco, G; Bianco, M; Bibi, S; Bigliardi, AP; Billheimer, D; Birnie, DH; Biswas, K; Blair, HC; Bognetti, P; Bolan, PJ; Bolla, JR; Bolze, A; Bonnaillie, P; Borlimi, R; Bórquez, J; Bottari, NB; Boulleys-Nana, JR; Brighetti, G; Brodeur, GM; Budnyak, T; Budnyk, S; Bukirwa, VD; Bulman, DM; Burm, R; Busman-Sahay, K; Butcher, TW; Cai, C; Cai, H; Cai, L; Cairati, M; Calvano, CD; Camacho-Ordóñez, A; Camela, E; Cameron, T; Campbell, BS; Cansian, RL; Cao, Y; Caporale, AS; Carciofi, AC; Cardozo, V; Carè, J; Carlos, AF; Carozza, R; Carroll, CJW; Carsetti, A; Carubelli, V; Casarotta, E; Casas, M; Caselli, G; Castillo-Lora, J; Cataldi, TRI; Cavalcante, ELB; Cavaleiro, A; Cayci, Z; Cebrián-Tarancón, C; Cedrone, E; Cella, D; Cereda, C; Ceretti, A; Ceroni, M; Cha, YH; Chai, X; Chang, EF; Chang, TS; Chanteux, H; Chao, M; Chaplin, BP; Chaturvedi, S; Chaturvedi, V; Chaudhary, DK; Chen, A; Chen, C; Chen, HY; Chen, J; Chen, JJ; Chen, K; Chen, L; Chen, Q; Chen, R; Chen, SY; Chen, TY; Chen, WM; Chen, X; Chen, Y; Cheng, G; Cheng, GJ; Cheng, J; Cheng, YH; Cheon, HG; Chew, KW; Chhoker, S; Chiu, WN; Choi, ES; Choi, MJ; Choi, SD; Chokshi, S; Chorny, M; Chu, KI; Chu, WJ; Church, AL; Cirrincione, A; Clamp, AR; Cleff, MB; Cohen, M; Coleman, RL; Collins, SL; Colombo, N; Conduit, N; Cong, WL; Connelly, MA; Connor, J; Cooley, K; Correa Ramos Leal, I; Cose, S; Costantino, C; Cottrell, M; Cui, L; Cundall, J; Cutaia, C; Cutler, CW; Cuypers, ML; da Silva Júnior, FMR; Dahal, RH; Damiani, E; Damtie, D; Dan-Li, W; Dang, Z; Dasa, SSK; Davin, A; Davis, DR; de Andrade, CM; de Jong, PL; de Oliveira, D; de Paula Dorigam, JC; Dean, A; Deepa, M; Delatour, C; Dell'Aiera, S; Delley, MF; den Boer, RB; Deng, L; Deng, Q; Depner, RM; Derdau, V; Derici, U; DeSantis, AJ; Desmarini, D; Diffo-Sonkoue, L; Divizia, M; Djenabou, A; Djordjevic, JT; Dobrovolskaia, MA; Domizi, R; Donati, A; Dong, Y; Dos Santos, M; Dos Santos, MP; Douglas, RG; Duarte, PF; Dullaart, RPF; Duscha, BD; Edwards, LA; Edwards, TE; Eichenwald, EC; El-Baba, TJ; Elashiry, M; Elashiry, MM; Elashry, SH; Elliott, A; Elsayed, R; Emerson, MS; Emmanuel, YO; Emory, TH; Endale-Mangamba, LM; Enten, GA; Estefanía-Fernández, K; Estes, JD; Estrada-Mena, FJ; Evans, S; Ezra, L; Faria de, RO; Farraj, AK; Favre, C; Feng, B; Feng, J; Feng, L; Feng, W; Feng, X; Feng, Z; Fernandes, CLF; Fernández-Cuadros, ME; Fernie, AR; Ferrari, D; Florindo, PR; Fong, PC; Fontes, EPB; Fontinha, D; Fornari, VJ; Fox, NP; Fu, Q; Fujitaka, Y; Fukuhara, K; Fumeaux, T; Fuqua, C; Fustinoni, S; Gabbanelli, V; Gaikwad, S; Gall, ET; Galli, A; Gancedo, MA; Gandhi, MM; Gao, D; Gao, K; Gao, M; Gao, Q; Gao, X; Gao, Y; Gaponenko, V; Garber, A; Garcia, EM; García-Campos, C; 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Monte, A; Monteiro, L; Montomoli, J; Moore, EE; Moore, HB; Moore, PK; Mor, MK; Moratalla-López, N; Moratilla Lapeña, L; Moreira, R; Moreno, MA; Mörk, AC; Morton, M; Mosier, JM; Mou, LH; Mougharbel, AS; Muccillo-Baisch, AL; Muñoz-Serrano, AJ; Mustafa, B; Nair, GM; Nakanishi, I; Nakanjako, D; Naraparaju, K; Nawani, N; Neffati, R; Neil, EC; Neilipovitz, D; Neira-Borrajo, I; Nelson, MT; Nery, PB; Nese, M; Nguyen, F; Nguyen, MH; Niazy, AA; Nicolaï, J; Nogueira, F; Norbäck, D; Novaretti, JV; O'Donnell, T; O'Dowd, A; O'Malley, DM; Oaknin, A; Ogata, K; Ohkubo, K; Ojha, M; Olaleye, MT; Olawande, B; Olomo, EJ; Ong, EWY; Ono, A; Onwumere, J; Ortiz Bibriesca, DM; Ou, X; Oza, AM; Ozturk, K; Özütemiz, C; Palacio-Pastrana, C; Palaparthi, A; Palevsky, PM; Pan, K; Pantanetti, S; Papachristou, DJ; Pariani, A; Parikh, CR; Parissis, J; Paroul, N; Parry, S; Patel, N; Patel, SM; Patel, VC; Pawar, S; Pefura-Yone, EW; Peixoto Andrade, BCO; Pelepenko, LE; Peña-Lora, D; Peng, S; Pérez-Moro, OS; Perez-Ortiz, AC; Perry, LM; Peter, CM; Phillips, NJ; Phillips, P; Pia Tek, J; Piner, LW; Pinto, EA; Pinto, SN; Piyachaturawat, P; Poka-Mayap, V; Polledri, E; Poloni, TE; Ponessa, G; Poole, ST; Post, AK; Potter, TM; Pressly, BB; Prouty, MG; Prudêncio, M; Pulkki, K; Pupier, C; Qian, H; Qian, ZP; Qiu, Y; Qu, G; Rahimi, S; Rahman, AU; Ramadan, H; Ramanna, S; Ramirez, I; Randolph, GJ; Rasheed, A; Rault, J; Raviprakash, V; Reale, E; Redpath, C; Rema, V; Remucal, CK; Remy, D; Ren, T; Ribeiro, LB; Riboli, G; Richards, J; Rieger, V; Rieusset, J; Riva, A; Rivabella Maknis, T; Robbins, JL; Robinson, CV; Roche-Campo, F; Rodriguez, R; Rodríguez-de-Cía, J; Rollenhagen, JE; Rosen, EP; Rub, D; Rubin, N; Rubin, NT; Ruurda, JP; Saad, O; Sabell, T; Saber, SE; Sabet, M; Sadek, MM; Saejio, A; Salinas, RM; Saliu, IO; Sande, D; Sang, D; Sangenito, LS; Santos, ALSD; Sarmiento Caldas, MC; Sassaroli, S; Sassi, V; Sato, J; Sauaia, A; Saunders, K; Saunders, PR; Savarino, SJ; Scambia, G; Scanlon, N; Schetinger, MR; Schinkel, AFL; Schladweiler, MC; Schofield, CJ; Schuepbach, RA; Schulz, J; Schwartz, N; Scorcella, C; Seeley, J; Seemann, F; Seinige, D; Sengoku, T; Seravalli, J; Sgromo, B; Shaheen, MY; Shan, L; Shanmugam, S; Shao, H; Sharma, S; Shaw, KJ; Shen, BQ; Shen, CH; Shen, P; Shen, S; Shen, Y; Shen, Z; Shi, J; Shi-Li, L; Shimoda, K; Shoji, Y; Shun, C; Silva, MA; Silva-Cardoso, J; Simas, NK; Simirgiotis, MJ; Sincock, SA; Singh, MP; Sionis, A; Siu, J; Sivieri, EM; Sjerps, MJ; Skoczen, SL; Slabon, A; Slette, IJ; Smith, MD; Smith, S; Smith, TG; Snapp, KS; Snow, SJ; Soares, MCF; Soberman, D; Solares, MD; Soliman, I; Song, J; Sorooshian, A; Sorrell, TC; Spinar, J; Staudt, A; Steinhart, C; Stern, ST; Stevens, DM; Stiers, KM; Stimming, U; Su, YG; Subbian, V; Suga, H; Sukhija-Cohen, A; Suksamrarn, A; Suksen, K; Sun, J; Sun, M; Sun, P; Sun, W; Sun, XF; Sun, Y; Sundell, J; Susan, LF; Sutjarit, N; Swamy, KV; Swisher, EM; Sykes, C; Takahashi, JA; Talmor, DS; Tan, B; Tan, ZK; Tang, L; Tang, S; Tanner, JJ; Tanwar, M; Tarazi, Z; 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Winkler, C; Wirman, AP; Wong, S; Woods, CM; Wu, B; Wu, C; Wu, F; Wu, P; Wu, S; Wu, Y; Wu, YN; Wu, ZH; Wurtzel, JGT; Xia, L; Xia, Z; Xia, ZZ; Xiao, H; Xie, C; Xin, ZM; Xing, Y; Xing, Z; Xu, S; Xu, SB; Xu, T; Xu, X; Xu, Y; Xue, L; Xun, J; Yaffe, MB; Yalew, A; Yamamoto, S; Yan, D; Yan, H; Yan, S; Yan, X; Yang, AD; Yang, E; Yang, H; Yang, J; Yang, JL; Yang, K; Yang, M; Yang, P; Yang, Q; Yang, S; Yang, W; Yang, X; Yang, Y; Yao, JC; Yao, WL; Yao, Y; Yaqub, TB; Ye, J; Ye, W; Yen, CW; Yeter, HH; Yin, C; Yip, V; Yong-Yi, J; Yu, HJ; Yu, MF; Yu, S; Yu, W; Yu, WW; Yu, X; Yuan, P; Yuan, Q; Yue, XY; Zaia, AA; Zakhary, SY; Zalwango, F; Zamalloa, A; Zamparo, P; Zampini, IC; Zani, JL; Zeitoun, R; Zeng, N; Zenteno, JC; Zepeda-Palacio, C; Zhai, C; Zhang, B; Zhang, G; Zhang, J; Zhang, K; Zhang, Q; Zhang, R; Zhang, T; Zhang, X; Zhang, Y; Zhang, YY; Zhao, B; Zhao, D; Zhao, G; Zhao, H; Zhao, Q; Zhao, R; Zhao, S; Zhao, T; Zhao, X; Zhao, XA; Zhao, Y; Zhao, Z; Zheng, Z; Zhi-Min, G; Zhou, CL; Zhou, HD; Zhou, J; Zhou, W; Zhou, XQ; Zhou, Z; Zhu, C; Zhu, H; Zhu, L; Zhu, Y; Zitzmann, N; Zou, L; Zou, Y, 2022) |
| "Clinical symptoms, cough symptom score, capsaicin cough sensitivity, gastroesophageal reflux diagnostic questionnaire (GerdQ) score, findings of multichannel intraluminal impedance-pH monitoring (MII-pH) and response to pharmacological anti-reflux therapy were retrospectively reviewed in 38 patients with non-acid GERC and compared with those of 49 patients with acid GERC." | 3.81 | Comparison of clinical characteristics of chronic cough due to non-acid and acid gastroesophageal reflux. ( Chen, Q; Liang, S; Lü, H; Qiu, Z; Xu, X; Yang, Z; Yu, L, 2015) |
| " The case presentation illustrates the role of pregabalin in successful medical management of this chronic pain disorder, as well as the management of common psychiatric morbidities associated with this condition." | 3.74 | Pregabalin-induced remission in a 62-year-old woman with a 20-year history of vulvodynia. ( Jerome, L, 2007) |
| " In the present study we have compared the expression profile of COX-2 protein, prostaglandin E2 (PGE2) levels and myeloperoxidase activity in acetic acid induced chronic gastric ulcer model in rats treated with omeprazole, misoprostol and COX-2 selective nonsteroidal anti-inflammatory drug (NSAID) celecoxib." | 3.73 | Cyclo-oxygenase-2 expression and prostaglandin E2 production in experimental chronic gastric ulcer healing. ( Gautam, P; Poonam, D; Vinay, CS, 2005) |
| " The patient was also treated with omeprazole (20 mg/day) because of chronic gastritis." | 3.73 | Gastric pH, sevelamer hydrochloride and omeprazole. ( Capitanini, A; Del Corso, C; Gallieni, M; Lupi, A; Osteri, F; Petrone, I; Rossi, A; Straniti, M, 2005) |
| "Our aims were to describe clinical characteristics of patients with chronic posterior laryngitis and to predict the response to omeprazole therapy." | 3.72 | Manifestations of gastroesophageal reflux and response to omeprazole therapy in patients with chronic posterior laryngitis: an evaluation based on clinical practice. ( Bastida, G; Bau, I; Garrigues, V; Gisbert, L; Nos, P; Ortiz, V; Ponce, J, 2003) |
| " CR 2945 was about as efficacious as ranitidine against the indomethacin- and ethanol-induced gastric ulcers and the cysteamine-induced duodenal ulcer in rats." | 3.70 | Characterization of antisecretory and antiulcer activity of CR 2945, a new potent and selective gastrin/CCK(B) receptor antagonist. ( Impicciatore, M; Letari, O; Makovec, F; Mennuni, L; Revel, L, 1999) |
| "We investigated the effect of probucol, a lipid-lowering agent with antioxidant properties, on HCl plus ethanol-induced gastric mucosal injury and on the healing of acetic acid-induced gastric ulcers in rats." | 3.70 | Anti-ulcer effects of antioxidants: effect of probucol. ( Ishihara, M; Ito, M; Suzuki, Y, 1998) |
| "These findings indicate that (1) peptic esophagitis was a common cause of chronic abdominal pain in pediatric patients and (2) omeprazole was effective in the treatment of esophagitis in children and adolescents that was resistant to high-dose histamine2-receptor antagonists." | 3.69 | Omeprazole treatment of children with peptic esophagitis refractory to ranitidine therapy. ( Kane, R; Karjoo, M, 1995) |
| "To evaluate the efficacy of one-week therapy with omeprazole, clarithromycin and amoxycillin in eradicating Helicobacter pylori and healing duodenal ulcer." | 3.69 | [One-week treatment with omeprazole, clarithromycin and amoxicillin: high efficacy in the eradication of Helicobacter pylori and cicatrization of duodenal ulcer]. ( Abraira, V; Alvarez Baleriola, I; Boixeda, D; Ceña, G; García Plaza, A; Gisbert, JP; Martín de Argila, C; Mur, M, 1997) |
| "We investigated the effects of cimetidine, omeprazole and atropine, antisecretory anti-ulcer agents, on the healing of gastric and duodenal ulcers simultaneously induced in the same rats." | 3.69 | Simultaneous evaluation of gastric and duodenal ulcers-healing activities of anti-ulcer agents in rats. ( Ito, M; Segami, T; Suzuki, Y, 1996) |
| " pylori with omeprazole and amoxicillin, the skin changes, gastric complaints, and proteinuria disappeared." | 3.69 | Schönlein-Henoch purpura associated with gastric Helicobacter pylori infection. ( Borchard, F; Goerz, G; Megahed, M; Reinauer, H; Reinauer, S; Ruzicka, T; Susanto, F, 1995) |
| " Thirty-two consecutive patients (suffering from either peptic ulcer or nonulcer dyspepsia) with Helicobacter pylori infection received omeprazole (40 mg) + bismuth subcitrate (240 mg x 4) + amoxicillin suspension (2000 mg x 4) + metronidazole (500 mg x 4), for only one day." | 3.68 | One-day therapy for treatment of Helicobacter pylori infection. ( Barbara, L; Biasco, G; Corinaldesi, R; Gasperoni, S; Paparo, GF; Ricci-Maccarini, M; Stanghellini, V; Tucci, A; Varoli, O, 1993) |
| "Evolution of gastrinoma tumoral mass, fasting serum gastrin concentrations, and gastric endocrine cells has been analyzed in 21 patients with the Zollinger-Ellison syndrome committed to long-term omeprazole treatment (up to 7." | 3.68 | Gastric endocrine cell evolution in patients with Zollinger-Ellison syndrome. Influence of gastrinoma growth and long-term omeprazole treatment. ( Bonfils, S; Cadiot, G; Lehy, T; Mignon, M; Ruszniewski, P, 1993) |
| "The effect of a proton pump inhibitor, omeprazole (OPZ), in combination with mouse epidermal growth factor (EGF), on the healing of chronic gastric ulcers induced by acetic acid in submandibular glands removed rats (SMR rat) was investigated." | 3.68 | [Effect of proton pump inhibitor, in combination with epidermal growth factor, on the healing of chronic gastric ulcer in submandibular gland removed rats]. ( Imai, S; Itoh, M; Joh, T; Takeuchi, T; Yokoyama, Y, 1992) |
| "Penetrated cysteamine-induced duodenal ulcers in rats have a very prolonged course of healing." | 3.67 | Effect of antisecretory agents and vagotomy on healing of "chronic" cysteamine-induced duodenal ulcers in rats. ( Kirkegaard, P; Poulsen, SS; Raaberg, L; Skov Olsen, P; Therkelsen, K, 1986) |
| " Secondary end-points were the rate of control of chronic cough at each step of therapy, the duration of treatment required, changes in cough symptom score, health-related quality of life and possible adverse effects." | 2.75 | Efficacy and safety of modified sequential three-step empirical therapy for chronic cough. ( Li, X; Liang, S; Liu, B; Lü, H; Qiu, Z; Wang, L; Wang, Y; Wei, W; Yu, L, 2010) |
| " A therapeutical scheme (omeprazole, metronidazole, amoxicilline) obtained a further pathogenetic substantiation of B type CG patient treatment with additional antioxidant vitamin E use at the dosage of 300 mg/day for three weeks." | 2.71 | [Lipid peroxidation and antioxidant system in treatment dynamics of patients with chronic gastritis]. ( Postavnyĭ, VE, 2005) |
| "Helicobacter pylori gastritis is usually a lifelong disease which can cause different topographical inflammatory reactions and induce divergent effects on acid secretion in humans." | 2.70 | Helicobacter pylori and different topographic types of gastritis: treatment response after successful eradication therapy in functional dyspepsia. ( Färkkilä, M; Koskenpato, J; Sipponen, P, 2002) |
| "Eleven patients with CRS and 19 GERD patients participated." | 2.70 | Role of GERD in chronic resistant sinusitis: a prospective, open label, pilot trial. ( DiBaise, JK; Huerter, JV; Olusola, BF; Quigley, EM, 2002) |
| "Omeprazole was given (40 mg/day) for 2 or 4 weeks." | 2.70 | Low incidence of Helicobacter pylori infection in patients with duodenal ulcer and chronic liver disease. ( Abdel-Baset, EZ; Atta, MM; Kabil, SM; Murray, JA; Nassar, AK; Shahin, WA, 2001) |
| "This single-center, open-label study was undertaken to compare the tolerability and pharmacokinetic profiles of rabeprazole, a new proton-pump inhibitor (PPI), in healthy volunteers and in subjects with chronic cirrhosis." | 2.69 | Rabeprazole: pharmacokinetics in patients with stable, compensated cirrhosis. ( Grimes, I; Hoyumpa, AM; Humphries, TJ; Trevino-Alanis, H, 1999) |
| "Chronic urticaria is one of the most frequent skin diseases." | 2.69 | Helicobacter pylori as a possible bacterial focus of chronic urticaria. ( Brehler, R; Domschke, W; Foerster, E; Luger, TA; Pohle, T; Wustlich, S, 1999) |
| "The ulcer recurrences appeared in patients with H." | 2.69 | [Reinfection with Helicobacter pylori in patients with duodenal ulcer after successful eradication]. ( Mach, T; Zahradnik-Bilska, J, 1999) |
| "Chronic urticaria is a common disease, though only few data on its natural course are available." | 2.69 | Chronic idiopathic urticaria: natural course and association with Helicobacter pylori infection. ( Helbling, A; Pichler, WJ; Schnyder, B, 1999) |
| "Fibrinogen changes were also significantly and negatively correlated with age." | 2.69 | Treatment of Helicobacter pylori and Chlamydia pneumoniae infections decreases fibrinogen plasma level in patients with ischemic heart disease. ( Arosio, C; Bertinieri, G; Blasi, F; Ceriani, G; Cosentini, R; Mandelli, C; Perondi, R; Ranzi, ML; Tarsia, P; Tien, TV; Torgano, G, 1999) |
| "Twenty-three patients were evaluated for gastroesophageal reflux disease; six (26%) were eventually determined to have an acid-related cough." | 2.69 | A prospective evaluation of esophageal testing and a double-blind, randomized study of omeprazole in a diagnostic and therapeutic algorithm for chronic cough. ( Kavuru, MS; Ours, TM; Richter, JE; Schilz, RJ, 1999) |
| " Group II (n = 47) treated with the same drug and dosage for 2 weeks." | 2.68 | [Omeprazole, clarithromycin and amoxicillin therapy for Helicobacter pylori infection]. ( Bei, L; Chen, S; Chen, Z, 1996) |
| "As GERD is often a chronic condition, we compared the long-term costs of medical and surgical management." | 2.68 | Lifetime costs of surgical versus medical treatment of severe gastro-oesophageal reflux disease in Finland. ( Isolauri, J; Nevalainen, J; Viljakka, M, 1997) |
| "Extraesophageal manifestations of gastroesophageal reflux disease (GERD) can include upper airway disorders, asthma and chronic cough." | 2.43 | Extraesophageal manifestations of GERD: diagnosis and therapy. ( Halstead, LA, 2005) |
| "Patient with GERD have a higher prevalence of asthma and chronic cough." | 2.41 | [Chronic respiratory disease and gastroesophageal reflux]. ( Dobashi, K, 2002) |
| "Gastroesophageal reflux disease (GERD) causes chronic cough and triggers asthma." | 2.41 | Chronic cough, asthma, and gastroesophageal reflux. ( Harding, SM; Lazenby, JP, 2000) |
| "Omeprazole has been shown to have a good long-term safety profile, as evaluated in these trials." | 2.39 | Long-term treatment of gastro-oesophageal reflux disease with omeprazole. ( Lundell, L, 1994) |
| "Gastroesophageal reflux disease (GERD) is recognized to be present in 10-20% of cases of chronic cough." | 2.39 | Excluding gastroesophageal reflux disease as the cause of chronic cough. ( Castell, DO; Gideon, RM; Johnston, BT, 1996) |
| "When lansoprazole was used as monotherapy, the mean Hp eradication was 6% in four studies." | 2.39 | Adjuvant therapy for Helicobacter pylori eradication: role of lansoprazole in clinical studies. ( Lamouliatte, H, 1995) |
| " Examination of eradication rates according to CAM dosage revealed an eradication rate of 65." | 1.40 | Changes in the first line Helicobacter pylori eradication rates using the triple therapy-a multicenter study in the Tokyo metropolitan area (Tokyo Helicobacter pylori study group). ( Asaoka, D; Ito, M; Kawai, T; Kawakami, K; Kurihara, N; Masaoaka, T; Matsuhisa, T; Mine, T; Mizuno, S; Nagahara, A; Nishizawa, T; Ohkusa, T; Omata, F; Sakaki, N; Sasaki, H; Suzuki, H; Suzuki, M; Takahashi, S; Tokunaga, K; Torii, A, 2014) |
| "Gastroesophageal reflux disease (GERD) is strongly associated with sleep disturbances." | 1.40 | Acid reflux directly causes sleep disturbances in rat with chronic esophagitis. ( Arakawa, T; Fujiwara, Y; Nakahara, K; Shiba, M; Tanigawa, T; Tominaga, K; Tsukahara, T; Urade, Y; Watanabe, T; Yamagami, H, 2014) |
| "Chronic urticaria is one of the most frequent skin diseases in medical practice." | 1.37 | Helicobacter pylori associated with chronic urticaria. ( Ben Mahmoud, L; Ghozzi, H; Hakim, A; Sahnoun, Z; Zeghal, K, 2011) |
| "Was performed an assessment of GERD symptom severity, the establishment of periodontal status of patients and analysis of the effects of GERD therapy on the course parodontopaty inflammatory genesis (chronic catarrhal gingivitis and chronic periodontitis mild)." | 1.36 | [Dynamics of inflammatory periodontal diseases under the influence of gastroesophageal reflux disease therapy]. ( Dzhamaldinova, TD, 2010) |
| "Chronic urticaria is a persistent urticaria lasting longer than 6 weeks, affecting 20% of the general population." | 1.35 | Helicobacter pylori infection in patients with chronic urticaria: correlation with pathologic findings in gastric biopsies. ( Abdou, AG; Elnaidany, NF; Elshayeb, EI; Farag, AG, 2009) |
| "The correlation between gastroesophageal reflux and several related variables was evaluated." | 1.35 | Gastroesophageal scintigraphy in the evaluation of adult patients with chronic cough due to gastroesophageal reflux disease. ( Cerci, SS; Oztürk, O; Sahin, U; Senol, A; Songür, N; Songür, Y; Yarktaş, MH, 2008) |
| "Gastroesophageal reflux disease (GERD) is commonly associated with asthma; however, frequency in nonatopic children with asthmatic symptoms is unknown." | 1.33 | Frequency of gastroesophageal reflux disease in nonatopic children with asthma-like airway disease. ( Aydoğdu, S; Kasirga, E; Kirmaz, C; Yilmaz, O; Yüksel, H, 2006) |
| "Blepharitis was diagnosed on the basis of findings in ophthalmic and dermatologic examinations." | 1.33 | Prevalence and treatment of Helicobacter pylori in patients with blepharitis. ( Baldi, F; Bilardi, C; Brusati, C; Mastromarino, A; Pascotto, A; Prigione, G; Rebora, A; Saccà, SC; Savarino, V; Venturino, GM, 2006) |
| "Twenty-nine patients (52%) had GERD plus another cause, and 3 patients (5%) had GERD with more than two causes." | 1.32 | Chronic cough and gastroesophageal reflux disease: experience with specific therapy for diagnosis and treatment. ( Kallay, MC; Poe, RH, 2003) |
| "It is reasoned that the GERD leads to nasopharyngitis and this to a chronic ear problem." | 1.31 | Chronic middle ear disease and gastroesophageal reflux disease: a causal relation? ( Feenstra, L; Poelmans, J; Tack, J, 2001) |
| "Chronic gastritis was diagnosed in 63 (77." | 1.31 | Detection of Helicobacter pylori colonization in dental plaques and tongue scrapings of patients with chronic gastritis. ( Ateşkan, U; Mas, MR; Ozdemir, A; Sağlamkaya, U; Sahin, S, 2001) |
| "Lactoferrin (Lf) is an iron-binding glycoprotein present in milk, lacrimae, saliva, and gastroduodenal secretions." | 1.30 | Relation of lactoferrin levels in gastric mucosa with Helicobacter pylori infection and with the degree of gastric inflammation. ( Ikemura, N; Imoto, I; Misaki, M; Nakao, K; Shibata, T; Taguchi, Y; Takaji, S; Yamauchi, K; Yamazaki, N, 1997) |
| "pylori infection is associated with hepatic encephalopathy, especially in younger patients with decompensated liver disease." | 1.30 | Analysis of risk factors for chronic hepatic encephalopathy: the role of Helicobacter pylori infection. ( Dasani, BM; Lieber, CS; Sigal, SH, 1998) |
| "The laryngitis was clinically and endoscopically unchanged in ten of the twelve (83." | 1.30 | [Is chronic laryngitis associated with Helicobacter pylori? Results of a prospective study]. ( Arps, H; Diehl, KL; Draf, W; Jaspersen, D; Kind, M; Weber, R, 1998) |
| "Omeprazole is a powerful inhibitor of gastric acid and may suppress Helicobacter pylori by effecting the pKa of H pylori urease, by altering the pattern of infection, or by promoting overgrowth of other bacteria." | 1.29 | Changes in the intragastric distribution of Helicobacter pylori during treatment with omeprazole. ( Baron, JH; Gummett, PA; Karim, QN; Logan, RP; Misiewicz, JJ; Walker, MM, 1995) |
| "Baclofen was used as a first treatment in patients without evidence of any gastro-oesophageal disease (n = 17), and was undertaken only after full treatment of such disease (n = 55) had failed to solve the hiccup problem (n = 20)." | 1.29 | Baclofen therapy for chronic hiccup. ( Bizec, JL; Cabane, J; Derenne, JP; Guelaud, C; Similowski, T; Whitelaw, WA, 1995) |
| "Gastroesophageal reflux may be responsible for atypical symptoms such as chronic cough and hoarseness." | 1.29 | Chronic cough and hoarseness in patients with severe gastroesophageal reflux disease. Diagnosis and response to therapy. ( Hunter, J; Katz, E; Lacayo, L; Suwak, B; Waring, JP, 1995) |
| "Although gastro-esophageal reflux (GER) is one of the major causes of chronic persistent cough (CPC) in the USA and in Europe, it is a rare cause of CPC in Japan." | 1.29 | [A case of chronic persistent cough caused by gastro-esophageal reflux]. ( Amemiya, T; Fujimura, M; Matsuda, T; Mizuguchi, M; Nishi, K; Ooka, T, 1995) |
| " Successful control of reflux disease in these patients was achieved by increasing omeprazole therapy to a regime and dosage that achieved elevation of intragastric pH above 4 throughout the 24-hour period." | 1.28 | Medical therapy of patients with reflux oesophagitis poorly responsive to H2-receptor antagonist therapy. ( Klinkenberg-Knol, EC; Meuwissen, SG, 1992) |
| " Following 10 mg intravenous omeprazole, plasma clearance was reduced, and plasma half-life and area under the concentration curve were increased, in comparison with previous studies in healthy subjects." | 1.27 | The anti-secretory effect and pharmacokinetics of omeprazole in chronic liver disease. ( Carter, DC; Forrest, JA; Garden, OJ; MacGilchrist, AJ; McKee, RF, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (1.97) | 18.7374 |
| 1990's | 67 (44.08) | 18.2507 |
| 2000's | 66 (43.42) | 29.6817 |
| 2010's | 15 (9.87) | 24.3611 |
| 2020's | 1 (0.66) | 2.80 |
| Authors | Studies |
|---|---|
| Nese, M | 1 |
| Riboli, G | 1 |
| Brighetti, G | 1 |
| Sassi, V | 1 |
| Camela, E | 1 |
| Caselli, G | 1 |
| Sassaroli, S | 1 |
| Borlimi, R | 1 |
| Aucoin, M | 1 |
| Cooley, K | 1 |
| Saunders, PR | 1 |
| Carè, J | 1 |
| Anheyer, D | 1 |
| Medina, DN | 1 |
| Cardozo, V | 1 |
| Remy, D | 1 |
| Hannan, N | 1 |
| Garber, A | 1 |
| Velayos, M | 1 |
| Muñoz-Serrano, AJ | 1 |
| Estefanía-Fernández, K | 1 |
| Sarmiento Caldas, MC | 1 |
| Moratilla Lapeña, L | 1 |
| López-Santamaría, M | 1 |
| López-Gutiérrez, JC | 1 |
| Li, J | 1 |
| Zhang, J | 1 |
| Shen, S | 1 |
| Zhang, B | 2 |
| Yu, WW | 1 |
| Toyoda, H | 1 |
| Huang, DQ | 1 |
| Le, MH | 1 |
| Nguyen, MH | 1 |
| Huang, R | 1 |
| Zhu, L | 1 |
| Wang, J | 6 |
| Xue, L | 1 |
| Liu, L | 2 |
| Yan, X | 2 |
| Huang, S | 1 |
| Li, Y | 6 |
| Xu, T | 1 |
| Li, C | 2 |
| Ji, F | 1 |
| Ming, F | 1 |
| Zhao, Y | 2 |
| Cheng, J | 1 |
| Wang, Y | 4 |
| Zhao, H | 1 |
| Hong, S | 1 |
| Chen, K | 2 |
| Zhao, XA | 1 |
| Zou, L | 1 |
| Sang, D | 1 |
| Shao, H | 1 |
| Guan, X | 1 |
| Chen, X | 2 |
| Chen, Y | 4 |
| Wei, J | 1 |
| Zhu, C | 1 |
| Wu, C | 1 |
| Moore, HB | 1 |
| Barrett, CD | 1 |
| Moore, EE | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Omeprazole 20 mg in Patients With Laryngopharyngeal reflux and Comorbid Chronic Rhinosinusitis - a Randomized, Double Blind, Placebo Controlled Trial[NCT03086070] | Phase 4 | 60 participants (Actual) | Interventional | 2010-01-01 | Completed | ||
| The Effect of Multiple Subcutaneous Doses of Risankizumab on the Single Dose Pharmacokinetics of Cytochrome P450 Substrates (Caffeine, Warfarin, Omeprazole, Metoprolol and Midazolam) Administered Orally in an Open-label, One-sequence Trial in Patients Wit[NCT02772601] | Phase 1 | 21 participants (Actual) | Interventional | 2016-09-15 | Completed | ||
| Clinical Application of Vagus Nerve Preservation in Minimally Invasive Surgery for Early Lung Cancer[NCT04125979] | 120 participants (Anticipated) | Interventional | 2019-01-01 | Recruiting | |||
| Prospective Randomized Controlled Study on the Effects of Vagus Nerve Pulmonary Branch Preservation During Video-assisted Thoracic Surgery Lobectomy in Non-small Cell Lung Cancer: Can it Decrease Postoperative Cough and Pulmonary Complications[NCT04923412] | 214 participants (Anticipated) | Interventional | 2021-07-01 | Recruiting | |||
| Assessing the Impacts of an Upper Esophageal Sphincter Assist Device on Laryngeal Symptoms and Salivary Pepsin: A Pilot Study[NCT02552966] | 20 participants (Actual) | Interventional | 2015-09-01 | Completed | |||
| Post-nasal Drainage as an Extraesophageal Manifestation of Reflux[NCT00199953] | Phase 2 | 50 participants | Interventional | 2002-06-30 | Completed | ||
| A Randomized, Placebo-Controlled Assessment of Lansoprazole 30 mg Bid in the Treatment of Gastroesophageal Reflux Associated With Laryngitis[NCT00369265] | Phase 4 | 18 participants (Actual) | Interventional | 2006-08-31 | Terminated (stopped due to Pharmaceutical company purchased by another company and funding was terminated.) | ||
| Open Label, Randomized, Single Site Clinical Trial To Compare The Safety Of Herbal Melanin Extracted From Nigella Sativa Seeds Vs Standard Of Care Treatment In Treating Gastritis Patients[NCT03428568] | Phase 2 | 132 participants (Anticipated) | Interventional | 2018-03-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
GERDQ score. Scale of 0-12, higher score indicates increased symptom severity. (NCT02552966)
Timeframe: 2 weeks
| Intervention | units on a scale (Mean) |
|---|---|
| UESAD | 8.6 |
NGSSI questionnaire score (NCT02552966)
Timeframe: 2 weeks
| Intervention | units on a scale (Mean) |
|---|---|
| UESAD | 26.8 |
Respiratory symptom index (RSI) score. Values between 0 and 45. Higher value is associated with increased symptom severity. (NCT02552966)
Timeframe: 2 weeks
| Intervention | units on a scale (Mean) |
|---|---|
| UESAD | 19.4 |
Average salivary pepsin concentration (NCT02552966)
Timeframe: 2 weeks
| Intervention | ng/mL (Mean) |
|---|---|
| UESAD | 158.4 |
12 reviews available for omeprazole and Chronic Illness
| Article | Year |
|---|---|
Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain; | 2022 |
[Chronic respiratory disease and gastroesophageal reflux].
Topics: Asthma; Chronic Disease; Cough; Diet Therapy; Gastroesophageal Reflux; Histamine H2 Antagonists; Hum | 2002 |
Extraesophageal manifestations of GERD: diagnosis and therapy.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Benzimidazoles; Chronic Disease; | 2005 |
Adjuvant therapy for Helicobacter pylori eradication: role of lansoprazole in clinical studies.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Bacterial Agents; Anti-Ulcer Agents; Chemotherapy, Adj | 1995 |
Long-term treatment of gastro-oesophageal reflux disease with omeprazole.
Topics: Chronic Disease; Clinical Trials as Topic; Gastroesophageal Reflux; Humans; Omeprazole | 1994 |
Refractory peptic lesions. Therapeutic strategies for ulcers and reflux esophagitis that resist standard regimens.
Topics: Anti-Ulcer Agents; Chronic Disease; Clinical Protocols; Combined Modality Therapy; Drug Therapy, Com | 1993 |
Excluding gastroesophageal reflux disease as the cause of chronic cough.
Topics: Anti-Ulcer Agents; Chronic Disease; Cough; Female; Gastroesophageal Reflux; Humans; Middle Aged; Ome | 1996 |
Helicobacter pylori infection, chronic gastritis, and proton pump inhibitors.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Bacterial Agents; Anti-Ulcer Agents; Benzimidazoles; C | 1998 |
Helicobacter pylori and idiopathic chronic urticaria.
Topics: Adult; Age Factors; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Breath Tests; Carbo | 2000 |
Chronic cough, asthma, and gastroesophageal reflux.
Topics: Anti-Ulcer Agents; Asthma; Chronic Disease; Cough; Gastroesophageal Reflux; Humans; Hydrogen-Ion Con | 2000 |
Refractory peptic ulcers.
Topics: Anti-Ulcer Agents; Chronic Disease; Cimetidine; Gastric Mucosa; Humans; Meta-Analysis as Topic; Omep | 1992 |
Update: gastroenterology and hepatology.
Topics: Chronic Disease; Esophageal Diseases; Gastrointestinal Diseases; Humans; Interferons; Liver Diseases | 1991 |
53 trials available for omeprazole and Chronic Illness
| Article | Year |
|---|---|
Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain; | 2022 |
Eight weeks of omeprazole 20 mg significantly reduces both laryngopharyngeal reflux and comorbid chronic rhinosinusitis signs and symptoms: Randomised, double-blind, placebo-controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Chronic Disease; Double-Blind Method; Drug Administration Schedule; | 2018 |
Lack of Effect of 12-Week Treatment with Risankizumab on the Pharmacokinetics of Cytochrome P450 Probe Substrates in Patients with Moderate to Severe Chronic Plaque Psoriasis.
Topics: Antibodies, Monoclonal; Area Under Curve; Caffeine; Chronic Disease; Cytochrome P-450 Enzyme System; | 2019 |
Efficacy and safety of modified sequential three-step empirical therapy for chronic cough.
Topics: Adult; Aminophylline; Antitussive Agents; Budesonide; Cetirizine; Chlorpheniramine; Chronic Disease; | 2010 |
Effect of eradication of Helicobacter pylori in children with chronic immune thrombocytopenia: a prospective, controlled, multicenter study.
Topics: Adolescent; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Blood Platelets; Child; Chronic D | 2011 |
Helicobacter pylori and different topographic types of gastritis: treatment response after successful eradication therapy in functional dyspepsia.
Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Biopsy; Breath Tests; Chronic Disease; Drug T | 2002 |
[Does intake of gastric acid pump inhibitor affect the evaluation of the Lundh test?].
Topics: Adult; Amylases; Anti-Ulcer Agents; Chronic Disease; Cross-Over Studies; Double-Blind Method; Duoden | 2002 |
[Esophageal epithelial cells renewal in evaluation of the pariet efficacy in the treatment of patients with reflux esophagitis].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Chronic Disease; Epithel | 2002 |
[Combination therapy of chronic pancreatitis (double-blind, placebo-controlled, pilot studies)].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Benzimidazoles; Chronic Disease; Double-Blind Method | 2003 |
Cure of Helicobacter pylori infection in patients with reflux oesophagitis treated with long term omeprazole reverses gastritis without exacerbation of reflux disease: results of a randomised controlled trial.
Topics: Adult; Aged; Anti-Bacterial Agents; Anti-Ulcer Agents; Chronic Disease; Disease Progression; Double- | 2004 |
Improvement in clinical course and laryngeal appearance in selected patients with chronic laryngitis after eight weeks of therapy with rabeprazole.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Benzimidazoles; Chronic Disease; Female; Human | 2004 |
Effect of Helicobacter pylori eradication on platelet recovery in patients with chronic idiopathic thrombocytopenic purpura.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Infective Agents; Chronic Disease; | 2004 |
Proton pump inhibitor therapy for chronic laryngo-pharyngitis: a randomized placebo-control trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Benzimidazoles; Chronic Disease; Double-Blind Method; Enzym | 2004 |
Influence of various proton pump inhibitors on intestinal metaplasia in noneradicated Helicobacter pylori patients.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Aged, 80 and over; Benzimidazoles; | 2005 |
Effect of high-dose aspirin on Helicobacter pylori eradication.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Aspirin; Chronic Disease; Clarithromyc | 2005 |
Role of chronic infection and inflammation in the gastrointestinal tract in the etiology and pathogenesis of idiopathic parkinsonism. Part 2: response of facets of clinical idiopathic parkinsonism to Helicobacter pylori eradication. A randomized, double-b
Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Chronic Disease; Clarithromycin; Double-Blind | 2005 |
Eradication of Helicobacter pylori infection reverses E-cadherin promoter hypermethylation.
Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Cadherins; Chronic Disease; Clarithromycin; D | 2006 |
Proton pump inhibitor treatment of patients with gastroesophageal reflux-related chronic cough: a comparison between two different daily doses of lansoprazole.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Ulcer Agents; Chronic Disease; Cough; Enz | 2006 |
[Lipid peroxidation and antioxidant system in treatment dynamics of patients with chronic gastritis].
Topics: Adult; Aged; alpha-Tocopherol; Amoxicillin; Anti-Infective Agents; Anti-Ulcer Agents; Antioxidants; | 2005 |
Thyroxine in goiter, Helicobacter pylori infection, and chronic gastritis.
Topics: Adult; Aged; Anti-Ulcer Agents; Chronic Disease; Gastric Acid; Gastritis; Goiter; Helicobacter Infec | 2006 |
Efficacy of lower than standard doses of pancreatic enzyme supplementation therapy during acid inhibition in patients with pancreatic exocrine insufficiency.
Topics: Adult; Aged; Chronic Disease; Drug Administration Schedule; Drug Therapy, Combination; Exocrine Panc | 2006 |
H. pylori infection in childhood chronic immune thrombocytopenic purpura.
Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Child; Child, Preschool; Chronic Disease; Cla | 2007 |
Evidence for the role of gastric mucosa at the secretion of soluble triggering receptor expressed on myeloid cells (strem-1) in peptic ulcer disease.
Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Chronic Disease; Clarithromycin; | 2007 |
Eradication of Helicobacter pylori infection equally improves chronic urticaria with positive and negative autologous serum skin test.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Autoantibodies; Chronic Disease; Clari | 2007 |
Distinct profiles of gastritis in dyspepsia subgroups. Their different clinical responses to gastritis healing after Helicobacter pylori eradication.
Topics: Adult; Age Factors; Amoxicillin; Chronic Disease; Drug Therapy, Combination; Dyspepsia; Female; Gast | 1994 |
A randomized blinded comparison of omeprazole and ranitidine in the treatment of chronic esophageal stricture secondary to acid peptic esophagitis.
Topics: Aged; Anti-Ulcer Agents; Chi-Square Distribution; Chronic Disease; Combined Modality Therapy; Dilata | 1996 |
Omeprazole-based dual and triple regimens for Helicobacter pylori eradication in children.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Ulcer Agents; Antibodies, Bacterial; Biopsy; Child; C | 1997 |
Lifetime costs of surgical versus medical treatment of severe gastro-oesophageal reflux disease in Finland.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Age Distribution; Aged; Chronic Disease; Cost of Ill | 1997 |
Parietal cell protrusions in gastric ulcer disease.
Topics: Chronic Disease; Double-Blind Method; Endoscopy, Digestive System; Gastric Mucosa; Gastritis; Helico | 1997 |
Adding once-daily omeprazole 20 mg to metronidazole/amoxicillin treatment for Helicobacter pylori gastritis: a randomized, double-blind trial showing the importance of metronidazole resistance.
Topics: Adolescent; Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Biopsy; Chronic Disease; C | 1998 |
Dual therapy with high or low doses of omeprazole does not achieve an acceptable rate of Helicobacter pylori eradication in duodenal ulcer patients. A multicentre randomized long-term detailed study.
Topics: Adolescent; Adult; Aged; Amoxicillin; Anti-Ulcer Agents; Chronic Disease; Dose-Response Relationship | 1997 |
[Omeprazole, clarithromycin and amoxicillin therapy for Helicobacter pylori infection].
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Chronic Disease; Clarithromycin; Drug | 1996 |
Chronic urticaria and Helicobacter pylori.
Topics: Adult; Anti-Bacterial Agents; Anti-Ulcer Agents; Antibodies, Bacterial; Blood Donors; Breath Tests; | 1998 |
Outcome of open antireflux surgery as assessed in a Nordic multicentre prospective clinical trial. Nordic GORD-Study Group.
Topics: Adolescent; Adult; Aged; Anti-Ulcer Agents; Chronic Disease; Female; Finland; Gastroesophageal Reflu | 1998 |
Effect of chronic duodenal ulceration and its treatment with lanzoprazole or sucralfate on gastroduodenal mucosal protein turnover and TGF-alpha, bFGF, and EGF receptor expression in humans.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Chronic Disease; Duodenal Ulcer; | 1998 |
Treatment of Helicobacter pylori and Chlamydia pneumoniae infections decreases fibrinogen plasma level in patients with ischemic heart disease.
Topics: Anti-Bacterial Agents; Anti-Ulcer Agents; Chlamydia Infections; Chlamydophila pneumoniae; Chronic Di | 1999 |
Helicobacter pylori as a possible bacterial focus of chronic urticaria.
Topics: Adult; Amoxicillin; Anti-Ulcer Agents; Chronic Disease; Drug Therapy, Combination; Female; Gastritis | 1999 |
Chronic idiopathic urticaria: natural course and association with Helicobacter pylori infection.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Amoxicillin; Chronic Disease; Cros | 1999 |
Rabeprazole: pharmacokinetics in patients with stable, compensated cirrhosis.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Benzimidazoles; Chronic Disease; Enzyme Inhibitors; | 1999 |
Inhibition of gastric secretion relieves diarrhea and postprandial urgency associated with irritable bowel syndrome or functional diarrhea.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Antacids; Anti-Ulcer Agents; Chronic Disease; Colonic Disea | 1999 |
Absence of benefit of eradicating Helicobacter pylori in patients with nonulcer dyspepsia.
Topics: Adolescent; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Chronic Disease; Cla | 1999 |
A prospective evaluation of esophageal testing and a double-blind, randomized study of omeprazole in a diagnostic and therapeutic algorithm for chronic cough.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Algorithms; Chronic Disease; Cough; Double-Blind Method; | 1999 |
[Reinfection with Helicobacter pylori in patients with duodenal ulcer after successful eradication].
Topics: Adult; Amoxicillin; Bismuth; Chronic Disease; Clarithromycin; Drug Therapy, Combination; Duodenal Ul | 1999 |
Garlic oil and Helicobacter pylori infection.
Topics: Adult; Allyl Compounds; Anti-Bacterial Agents; Anti-Ulcer Agents; Chronic Disease; Disulfides; Dyspe | 2000 |
Omeprazole for treatment of chronic erosive esophagitis in children: a multicenter study of efficacy, safety, tolerability and dose requirements. International Pediatric Omeprazole Study Group.
Topics: Adolescent; Anti-Ulcer Agents; Child; Child, Preschool; Chronic Disease; Dose-Response Relationship, | 2000 |
Lansoprazole treatment of patients with chronic idiopathic laryngitis: a placebo-controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Chronic Disease; Double-Blind Method; Female; Gastroe | 2001 |
Lansoprazole treatment of patients with chronic idiopathic laryngitis: a placebo-controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Chronic Disease; Double-Blind Method; Female; Gastroe | 2001 |
Lansoprazole treatment of patients with chronic idiopathic laryngitis: a placebo-controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Chronic Disease; Double-Blind Method; Female; Gastroe | 2001 |
Lansoprazole treatment of patients with chronic idiopathic laryngitis: a placebo-controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Chronic Disease; Double-Blind Method; Female; Gastroe | 2001 |
Lansoprazole treatment of patients with chronic idiopathic laryngitis: a placebo-controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Chronic Disease; Double-Blind Method; Female; Gastroe | 2001 |
Lansoprazole treatment of patients with chronic idiopathic laryngitis: a placebo-controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Chronic Disease; Double-Blind Method; Female; Gastroe | 2001 |
Lansoprazole treatment of patients with chronic idiopathic laryngitis: a placebo-controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Chronic Disease; Double-Blind Method; Female; Gastroe | 2001 |
Lansoprazole treatment of patients with chronic idiopathic laryngitis: a placebo-controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Chronic Disease; Double-Blind Method; Female; Gastroe | 2001 |
Lansoprazole treatment of patients with chronic idiopathic laryngitis: a placebo-controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Chronic Disease; Double-Blind Method; Female; Gastroe | 2001 |
Low incidence of Helicobacter pylori infection in patients with duodenal ulcer and chronic liver disease.
Topics: Adult; Anti-Ulcer Agents; Chronic Disease; Duodenal Ulcer; Female; Helicobacter Infections; Helicoba | 2001 |
Helicobacter pylori and iron deficiency anaemia in children.
Topics: Adolescent; Amoxicillin; Anemia, Iron-Deficiency; Anti-Bacterial Agents; Anti-Ulcer Agents; Breath T | 2001 |
Therapeutic effects of antibacterial treatment for intractable skin diseases in Helicobacter pylori-positive Japanese patients.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin; An | 2002 |
Role of GERD in chronic resistant sinusitis: a prospective, open label, pilot trial.
Topics: Adult; Chronic Disease; Drug Resistance; Enzyme Inhibitors; Female; Gastroesophageal Reflux; Humans; | 2002 |
Short-term treatment of refractory reflux esophagitis with different doses of omeprazole or ranitidine.
Topics: Adult; Chronic Disease; Double-Blind Method; Drug Administration Schedule; Drug Resistance; Esophagi | 1992 |
Effect of omeprazole on duodenal ulcer-associated antral gastritis and Helicobacter pylori.
Topics: Adult; Chronic Disease; Double-Blind Method; Duodenal Ulcer; Female; Gastritis; Helicobacter Infecti | 1991 |
Effect of long-term treatment with omeprazole on serum gastrin and serum group A and C pepsinogens in patients with reflux esophagitis.
Topics: Aged; Chronic Disease; Drug Administration Schedule; Esophagitis, Peptic; Female; Gastrectomy; Gastr | 1990 |
88 other studies available for omeprazole and Chronic Illness
| Article | Year |
|---|---|
Helicobacter pylori in esplenectomized patients with immune primary trombocytopenia
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Chronic Disease; Clarithromycin; Drug Therapy, Combinatio | 2017 |
Comparison of clinical characteristics of chronic cough due to non-acid and acid gastroesophageal reflux.
Topics: Adult; Anti-Ulcer Agents; Baclofen; Capsaicin; Chronic Disease; Cough; Domperidone; Esophageal pH Mo | 2015 |
Gastritis due to Helicobacter pylori, an unusual cause of chronic diarrhoea in HIV infected patients.
Topics: Aged; Amoxicillin; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Breath Tests; Chronic Dis | 2014 |
Acid reflux directly causes sleep disturbances in rat with chronic esophagitis.
Topics: Animals; Chronic Disease; Esophagitis, Peptic; Esophagus; Gastric Acid; Gastric Juice; Gastroesophag | 2014 |
Changes in the first line Helicobacter pylori eradication rates using the triple therapy-a multicenter study in the Tokyo metropolitan area (Tokyo Helicobacter pylori study group).
Topics: Amoxicillin; Chronic Disease; Clarithromycin; Disease Eradication; Female; Gastritis; Helicobacter I | 2014 |
Oropharyngeal pH Testing Does Not Predict Response to Proton Pump Inhibitor Therapy in Patients with Laryngeal Symptoms.
Topics: Adult; Chronic Disease; Cohort Studies; Cough; Deglutition Disorders; Female; Hoarseness; Humans; Hy | 2016 |
Omeprazole and refractory hypomagnesaemia.
Topics: Aged; Aged, 80 and over; Anti-Ulcer Agents; Chronic Disease; Female; Humans; Hypocalcemia; Hypokalem | 2008 |
Gastroesophageal scintigraphy in the evaluation of adult patients with chronic cough due to gastroesophageal reflux disease.
Topics: Adult; Aged; Case-Control Studies; Chronic Disease; Cough; Esophagitis, Peptic; Esophagus; Female; G | 2008 |
Effects of helicobacter pylori eradication on chronic nonspecific pharyngeal symptoms.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Breath Tests; Chronic Disease; Cohort | 2008 |
Helicobacter pylori infection in patients with chronic urticaria: correlation with pathologic findings in gastric biopsies.
Topics: Adult; Aged; Amoxicillin; Anti-Infective Agents; Biopsy; Case-Control Studies; Chronic Disease; Fema | 2009 |
[Effect of eradication therapy on nitrogen oxide activity in the gastric juice of patients with chronic gastritis and ulcer disease].
Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Chronic Disease; Clarithromycin; Drug Therapy, Comb | 2009 |
[Dynamics of inflammatory periodontal diseases under the influence of gastroesophageal reflux disease therapy].
Topics: Adult; Alginates; Chronic Disease; Chronic Periodontitis; Drug Therapy, Combination; Enzyme Inhibito | 2010 |
Hoarseness and chronic cough: would you suspect reflux?
Topics: Adult; Chronic Disease; Cough; Diagnosis, Differential; Drug Therapy, Combination; Female; Fundoplic | 2011 |
Helicobacter pylori associated with chronic urticaria.
Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Antibodies, Bacterial; Chronic Disease; Clari | 2011 |
[Primary antibiotic resistance of Helicobacter pylori strains and eradication rate according to gastroduodenal disease in Korea].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Chronic Di | 2011 |
Combatting the cough that won't quit.
Topics: Algorithms; Anti-Ulcer Agents; Chronic Disease; Cough; Diagnosis, Differential; Family Practice; Fem | 2012 |
Improvement of long-standing iron-deficiency anemia in adults after eradication of Helicobacter pylori infection.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anemia, Iron-Deficiency; Anti-Bacterial | 2002 |
Chronic urticaria induced by eradication therapy of Helicobacter pylori: a case report.
Topics: Amoxicillin; Anti-Bacterial Agents; Chronic Disease; Clarithromycin; Helicobacter Infections; Helico | 2002 |
Prospective study on the incidence of chronic ear complaints related to gastroesophageal reflux and on the outcome of antireflux therapy.
Topics: Adult; Aged; Anti-Ulcer Agents; Chronic Disease; Cohort Studies; Enzyme Inhibitors; Female; Gastroes | 2002 |
[A case for proton pump blocker... When cough comes from the stomach].
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antirheumatic Age | 2002 |
[Clinical aspects of using pariet in treating chronic pancreatitis].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Benzimidazoles; Chronic Disease; Enzyme Inhibitors; Humans; | 2002 |
Chronic cough and gastroesophageal reflux disease: experience with specific therapy for diagnosis and treatment.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Chronic Disease; Cisapride; | 2003 |
Manifestations of gastroesophageal reflux and response to omeprazole therapy in patients with chronic posterior laryngitis: an evaluation based on clinical practice.
Topics: Adolescent; Adult; Aged; Anti-Ulcer Agents; Chronic Disease; Female; Gastroesophageal Reflux; Humans | 2003 |
Elevated quetiapine serum concentrations in a patient treated concomitantly with doxepin, lorazepam, and pantoprazole.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Antidepressive Agents, Tricyclic; Antipsychotic Agen | 2004 |
Persistent cough following pulmonary resection: observational and empiric study of possible causes.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Benzamides; Carcinoma, Non-Small-Cell Lung; Chronic D | 2005 |
Persistent cough following pulmonary resection: observational and empiric study of possible causes.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Benzamides; Carcinoma, Non-Small-Cell Lung; Chronic D | 2005 |
Persistent cough following pulmonary resection: observational and empiric study of possible causes.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Benzamides; Carcinoma, Non-Small-Cell Lung; Chronic D | 2005 |
Persistent cough following pulmonary resection: observational and empiric study of possible causes.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Benzamides; Carcinoma, Non-Small-Cell Lung; Chronic D | 2005 |
[Helicobacter pylori infection in patients with chronic hives and asthma].
Topics: Adolescent; Adult; Anti-Bacterial Agents; Antibodies, Bacterial; Asthma; Chronic Disease; Clarithrom | 2005 |
Frequency of gastroesophageal reflux disease in nonatopic children with asthma-like airway disease.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Asthmatic Agents; Anti-Ulcer Agents; Asthma; Child; Ch | 2006 |
Altered expression of Skp2, c-Myc and p27 proteins but not mRNA after H. pylori eradication in chronic gastritis.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer | 2006 |
Cyclo-oxygenase-2 expression and prostaglandin E2 production in experimental chronic gastric ulcer healing.
Topics: Animals; Anti-Ulcer Agents; Blotting, Western; Celecoxib; Chronic Disease; Cyclooxygenase 2; Dinopro | 2005 |
Gastric pH, sevelamer hydrochloride and omeprazole.
Topics: Adult; Anti-Ulcer Agents; Chronic Disease; Dose-Response Relationship, Drug; Drug Interactions; Fema | 2005 |
Prevalence and treatment of Helicobacter pylori in patients with blepharitis.
Topics: Adult; Anti-Bacterial Agents; Blepharitis; Breath Tests; Chronic Disease; Drug Therapy, Combination; | 2006 |
Pantoprazole and perinuclear antineutrophil cytoplasmic antibody-associated vasculitis.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acute Disease; Aged; Anti-Ulcer Agents; Antibodies, Antineu | 2006 |
Microscopic colitis associated with exposure to lansoprazole.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Biopsy; Chronic Disease; Colitis, Collagenous; Coliti | 2006 |
Esophageal intramural pseudodiverticulosis with esophageal strictures successfully treated with dilation therapy.
Topics: Aged; Antifungal Agents; Candidiasis; Catheterization; Chronic Disease; Deglutition Disorders; Diagn | 2006 |
Duodenal gastric metaplasia and Helicobacter pylori infection in patients with diffuse nodular duodenitis.
Topics: Adult; Aged; Case-Control Studies; Chronic Disease; Clarithromycin; Drug Therapy, Combination; Duode | 2007 |
[The 10-minute-consultation: chronic singultus].
Topics: Aged; Amines; Anti-Ulcer Agents; Anticonvulsants; Chronic Disease; Cyclohexanecarboxylic Acids; Diag | 2007 |
Pregabalin-induced remission in a 62-year-old woman with a 20-year history of vulvodynia.
Topics: Amitriptyline; Analgesics; Anti-Ulcer Agents; Anticoagulants; Antidepressive Agents; Anxiety; Cardio | 2007 |
Chronic urticaria and Helicobacter pylori.
Topics: Adolescent; Adult; Amoxicillin; Case-Control Studies; Chronic Disease; Comorbidity; Drug Therapy, Co | 2008 |
[Association of gastroesophageal reflux and chronic laryngitis].
Topics: Adult; Aged; Anti-Ulcer Agents; Chronic Disease; Endoscopy, Digestive System; Female; Gastroesophage | 1995 |
Schönlein-Henoch purpura associated with gastric Helicobacter pylori infection.
Topics: Adult; Amoxicillin; Anti-Ulcer Agents; Biopsy; Breath Tests; Chronic Disease; Drug Therapy, Combinat | 1995 |
Outcomes of antireflux therapy for the treatment of chronic laryngitis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Chronic Disease; Famotidine; Female; Gastroesopha | 1995 |
[A case of chronic persistent cough caused by gastro-esophageal reflux].
Topics: Aged; Chronic Disease; Cimetidine; Cough; Female; Gastroesophageal Reflux; Histamine H2 Antagonists; | 1995 |
Treatment of pyrosis does not insure adequate control of gastric acid reflux.
Topics: Barrett Esophagus; Chronic Disease; Esophagitis; Gastroesophageal Reflux; Heartburn; Humans; Hydroge | 1995 |
Chronic cough and hoarseness in patients with severe gastroesophageal reflux disease. Diagnosis and response to therapy.
Topics: Case-Control Studies; Chronic Disease; Cough; Female; Fundoplication; Gastroesophageal Reflux; Heart | 1995 |
Baclofen therapy for chronic hiccup.
Topics: Anti-Ulcer Agents; Baclofen; Chronic Disease; Cisapride; Dose-Response Relationship, Drug; Female; G | 1995 |
Omeprazole treatment of children with peptic esophagitis refractory to ranitidine therapy.
Topics: Abdominal Pain; Adolescent; Child; Chronic Disease; Drug Resistance; Esophagitis, Peptic; Gastritis; | 1995 |
Changes in the intragastric distribution of Helicobacter pylori during treatment with omeprazole.
Topics: Acute Disease; Adolescent; Adult; Aged; Breath Tests; Chronic Disease; Duodenal Ulcer; Esophagitis, | 1995 |
Gastric endocrine cell evolution in patients with Zollinger-Ellison syndrome. Influence of gastrinoma growth and long-term omeprazole treatment.
Topics: Adult; Aged; APUD Cells; Chi-Square Distribution; Chronic Disease; Female; Gastrinoma; Gastrins; Hum | 1993 |
One-day therapy for treatment of Helicobacter pylori infection.
Topics: Adult; Amoxicillin; Anti-Ulcer Agents; Chronic Disease; Drug Administration Schedule; Drug Therapy, | 1993 |
Wrong-way swallowing as a possible cause of bronchitis in patients with gastroesophageal reflux disease.
Topics: Bronchitis; Chronic Disease; Cough; Deglutition Disorders; Female; Gastroesophageal Reflux; Hernia, | 1993 |
Dysphonia as an atypical presentation of gastro-oesophageal reflux.
Topics: Adult; Anti-Ulcer Agents; Chronic Disease; Female; Gastroesophageal Reflux; Humans; Male; Middle Age | 1995 |
Should omeprazole be used for the treatment and prevention of duodenal ulcer as a monotherapeutic agent?
Topics: Anti-Ulcer Agents; Chronic Disease; Duodenal Ulcer; Helicobacter Infections; Helicobacter pylori; Hu | 1996 |
Simultaneous evaluation of gastric and duodenal ulcers-healing activities of anti-ulcer agents in rats.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Atropine; Chronic Disease; Cimetidine; Duodenal Ulcer; Hist | 1996 |
[Association of chronic urticaria with Helicobacter pylori-induced antrum gastritis].
Topics: Adult; Amoxicillin; Chronic Disease; Drug Therapy, Combination; Female; Gastritis; Helicobacter Infe | 1996 |
Eradication of helicobacter pylori among patients from a primary care practice.
Topics: Adult; Anti-Bacterial Agents; Anti-Ulcer Agents; Chronic Disease; Drug Therapy, Combination; Endosco | 1996 |
Proton-pump inhibition of gastric chloride secretion in congenital chloridorrhea.
Topics: Adult; Chlorides; Chronic Disease; Diarrhea; Feces; Gastric Mucosa; Humans; Hypokalemia; Intestinal | 1997 |
Effect of omeprazole on the course of associated esophagitis and laryngitis.
Topics: Adult; Aged; Anti-Ulcer Agents; Chronic Disease; Esophagitis, Peptic; Esophagoscopy; Female; Follow- | 1996 |
Relation of lactoferrin levels in gastric mucosa with Helicobacter pylori infection and with the degree of gastric inflammation.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Ammonia; Anti-Bacterial Agents; Anti-Ulcer Agents; Biomarke | 1997 |
[One-week treatment with omeprazole, clarithromycin and amoxicillin: high efficacy in the eradication of Helicobacter pylori and cicatrization of duodenal ulcer].
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Chronic Disease; Clarithromycin; Drug | 1997 |
Does Helicobacter pylori infection affect gastric emptying in patients with functional dyspepsia?
Topics: Adolescent; Adult; Amoxicillin; Anti-Ulcer Agents; Chronic Disease; Dyspepsia; Female; Gastric Empty | 1997 |
[Helicobacter pylori infection and recurrent abdominal pain in children. A proved relationship?].
Topics: Abdominal Pain; Adolescent; Adult; Age Factors; Amoxicillin; Antacids; Anti-Bacterial Agents; Anti-U | 1998 |
Natural history of severe duodenal ulcer disease.
Topics: Adult; Aged; Anti-Ulcer Agents; Chronic Disease; Drug Therapy, Combination; Duodenal Ulcer; Female; | 1998 |
Analysis of risk factors for chronic hepatic encephalopathy: the role of Helicobacter pylori infection.
Topics: Ammonia; Amoxicillin; Anti-Ulcer Agents; Ascites; Chronic Disease; Diuretics; Helicobacter Infection | 1998 |
[Is chronic laryngitis associated with Helicobacter pylori? Results of a prospective study].
Topics: Adult; Aged; Anti-Ulcer Agents; Biopsy; Chronic Disease; Esophagitis, Peptic; Female; Follow-Up Stud | 1998 |
[ETICS Study: Empirical therapy of idiopathic chronic singultus].
Topics: Acetates; Aged; Aged, 80 and over; Amines; Baclofen; Chronic Disease; Cisapride; Cyclohexanecarboxyl | 1998 |
Anti-ulcer effects of antioxidants: effect of probucol.
Topics: Acetic Acid; Acute Disease; Animals; Anti-Ulcer Agents; Antioxidants; Chronic Disease; Cimetidine; D | 1998 |
Characterization of antisecretory and antiulcer activity of CR 2945, a new potent and selective gastrin/CCK(B) receptor antagonist.
Topics: Animals; Anti-Anxiety Agents; Anti-Ulcer Agents; Benzodiazepines; Benzodiazepinones; Calcium; Cats; | 1999 |
Eradication of Helicobacter pylori normalizes elevated mucosal levels of epidermal growth factor and its receptor.
Topics: Adult; Antacids; Anti-Bacterial Agents; Anti-Ulcer Agents; Biopsy; Bismuth; Chronic Disease; Drug Th | 1999 |
Accurately diagnosing and successfully treating chronic cough due to gastroesophageal reflux disease can be difficult.
Topics: Antacids; Asthma; Chronic Disease; Consensus Development Conferences as Topic; Cough; Diagnosis, Dif | 1999 |
[Congress of the American College of Surgeons (ACS). San Francisco, 10-15 October 1999].
Topics: Anti-Ulcer Agents; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Carcinoma, Hepatocellular; Cholang | 1999 |
Risk factors for esophageal candidiasis.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Ulcer Agents; Candidiasis; Case-Control Studies | 2000 |
Ex juvantibus approach for chronic posterior laryngitis: results of short-term pantoprazole therapy.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Benzimidazoles; Chronic Disease; | 1999 |
Gabapentin "add-on therapy" for idiopathic chronic hiccup (ICH).
Topics: Acetates; Aged; Amines; Baclofen; Chronic Disease; Cisapride; Cyclohexanecarboxylic Acids; Drug Admi | 2000 |
Peptic ulcer occurrence in follow-up of chronic gastritis in patients with treated and not eradicated CagA-positive Helicobacter pylori infection.
Topics: Adult; Aged; Amoxicillin; Anti-Ulcer Agents; Antigens, Bacterial; Bacterial Proteins; Chronic Diseas | 2001 |
Chronic middle ear disease and gastroesophageal reflux disease: a causal relation?
Topics: Adult; Aged; Anti-Ulcer Agents; Chronic Disease; Combined Modality Therapy; Endoscopy; Female; Gastr | 2001 |
[The effectiveness of 7-day combined Helicobacter eradication therapy in patients with peptic ulcer and chronic gastritis].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Aged, 80 and over; Anti-Ulcer Agents; Chronic Disease | 2001 |
Helicobacter pylori eradication in functional dyspepsia: new evidence for symptomatic benefit.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Chronic Disease; Dyspepsia; Gastritis; Helicobacter Infecti | 2001 |
Mutagenic and clastogenic activity of gastric juice in human gastric diseases.
Topics: Adult; Aged; Anti-Ulcer Agents; Chronic Disease; Female; Gastric Juice; Gastritis, Atrophic; Humans; | 2002 |
Chronic gastric ulcer healing in rats subjected to selective and non-selective cyclooxygenase-2 inhibitors.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Chronic Disease; | 2002 |
Detection of Helicobacter pylori colonization in dental plaques and tongue scrapings of patients with chronic gastritis.
Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Biopsy; Chronic Disease; Clarith | 2001 |
[Effect of proton pump inhibitor, in combination with epidermal growth factor, on the healing of chronic gastric ulcer in submandibular gland removed rats].
Topics: Acetates; Acetic Acid; Adenosine Triphosphatases; Animals; Chronic Disease; Drug Therapy, Combinatio | 1992 |
Medical therapy of patients with reflux oesophagitis poorly responsive to H2-receptor antagonist therapy.
Topics: Administration, Oral; Chronic Disease; Esophagitis, Peptic; Follow-Up Studies; Gastric Acidity Deter | 1992 |
[Drug therapy of peptic ulcer disease].
Topics: Anti-Bacterial Agents; Anti-Ulcer Agents; Chronic Disease; Helicobacter Infections; Histamine H2 Ant | 1991 |
Intragastric pH in the gastroprotective and ulcer-healing activity of aluminum-containing antacids.
Topics: Acute Disease; Aluminum Hydroxide; Animals; Antacids; Chronic Disease; Drug Combinations; Ethanol; F | 1991 |
Comparative efficacy of acid reflux inhibition by drug therapy in reflux esophagitis.
Topics: Adult; Aged; Chronic Disease; Cisapride; Esophagitis, Peptic; Esophagus; Famotidine; Female; Humans; | 1991 |
The anti-secretory effect and pharmacokinetics of omeprazole in chronic liver disease.
Topics: Adult; Chronic Disease; Female; Gastric Acid; Humans; Liver Diseases; Male; Middle Aged; Omeprazole | 1988 |
Effect of antisecretory agents and vagotomy on healing of "chronic" cysteamine-induced duodenal ulcers in rats.
Topics: Animals; Anti-Ulcer Agents; Benzimidazoles; Brunner Glands; Chronic Disease; Cimetidine; Cysteamine; | 1986 |
[Effects of omeprazole, a benzimidazole derivative, on the gastric mucosal blood flow in chronic gastric ulcer in humans].
Topics: Aged; Anti-Ulcer Agents; Benzimidazoles; Chronic Disease; Gastric Mucosa; Humans; Omeprazole; Region | 1986 |