Page last updated: 2024-11-01

omeprazole and Cholestasis

omeprazole has been researched along with Cholestasis in 5 studies

Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.

Cholestasis: Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).

Research Excerpts

ExcerptRelevanceReference
"Patients treated for cholestasis or liver diseases were removed."5.51Population Scale Retrospective Analysis Reveals Potential Risk of Cholestasis in Pregnant Women Taking Omeprazole, Lansoprazole, and Amoxicillin. ( Abagyan, R; Dai, W; Dong, M; Shi, D; Zhang, Y, 2019)
" This study aimed to develop an animal model to examine the effects of long-term use of PPI in vivo."1.56Long-term Proton Pump Inhibitor Administration Caused Physiological and Microbiota Changes in Rats. ( Chang, HW; Chang, VHS; Chien, LN; Chu, PG; Dong, F; Jia, W; Lin, IH; Liu, YR; Wu, MJ; Xie, G; Yang, YSH; Yen, Y, 2020)
"Patients treated for cholestasis or liver diseases were removed."1.51Population Scale Retrospective Analysis Reveals Potential Risk of Cholestasis in Pregnant Women Taking Omeprazole, Lansoprazole, and Amoxicillin. ( Abagyan, R; Dai, W; Dong, M; Shi, D; Zhang, Y, 2019)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Yang, YSH1
Chang, HW1
Lin, IH1
Chien, LN1
Wu, MJ1
Liu, YR1
Chu, PG1
Xie, G1
Dong, F1
Jia, W1
Chang, VHS1
Yen, Y1
Zhang, Y1
Shi, D1
Abagyan, R1
Dai, W1
Dong, M1
Dahlke, MH1
Aselmann, H1
Ceylan, D1
Bellin, T1
Flemming, P1
Meier, PN1
Oldhafer, K1
Klempnauer, J1
Schlitt, HJ1
Piso, P1
Mertens, PR1
Schönfelder, T1
Handt, S1
Kierdorf, H1
Marschall, H1
Busch, N1
Heintz, B1
Sieberth, H1
Namba, S1

Other Studies

5 other studies available for omeprazole and Cholestasis

ArticleYear
Long-term Proton Pump Inhibitor Administration Caused Physiological and Microbiota Changes in Rats.
    Scientific reports, 2020, 01-21, Volume: 10, Issue:1

    Topics: Administration, Oral; alpha-Tocopherol; Animals; Bile Duct Neoplasms; Bile Ducts; Cell Transformatio

2020
Population Scale Retrospective Analysis Reveals Potential Risk of Cholestasis in Pregnant Women Taking Omeprazole, Lansoprazole, and Amoxicillin.
    Interdisciplinary sciences, computational life sciences, 2019, Volume: 11, Issue:2

    Topics: Adolescent; Adult; Amoxicillin; Child; Cholestasis; Drug Therapy, Combination; Female; Humans; Lanso

2019
Effectiveness of peripheral hepatogastrostomy versus hepatojejunostomy in the treatment of obstructive cholestasis: results of an experimental model.
    Surgery today, 2004, Volume: 34, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Benzimidazoles; Cholestasis; Common Bile Duct; Fea

2004
Long-term extracorporeal bilirubin elimination: A case report on cascade resin plasmaperfusion.
    Blood purification, 1998, Volume: 16, Issue:6

    Topics: Acute Kidney Injury; Bile Acids and Salts; Charcoal; Chemical and Drug Induced Liver Injury; Cholest

1998
[Inhibitory effects of omeprazole and cimetidine on the formation of gastric ulcer in rats with obstructive jaundice and acute renal failure].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1988, Volume: 85, Issue:6

    Topics: Acute Kidney Injury; Animals; Cholestasis; Cimetidine; Gastric Mucosa; Male; Omeprazole; Rats; Rats,

1988