omeprazole has been researched along with Canine Diseases in 21 studies
Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gastroesophageal reflux was observed in 55% (11/20) of control dogs, 55% (11/20) of dogs receiving omeprazole once and 47% (7/15) of dogs receiving omeprazole twice." | 9.41 | Effect of two different pre-anaesthetic omeprazole protocols on gastroesophageal reflux incidence and pH in dogs. ( Boscan, P; Bryan, S; Fukushima, K; Krause, L; Lotti, F; Twedt, D; Vaca, C; Warrit, K, 2021) |
| "To determine the incidence of bacteremia, as detected by routine methods for bacterial culture of blood samples, following routine endoscopic biopsy of the stomach and duodenum in healthy research dogs and to determine whether treatment with omeprazole administration affected the incidence of bacteremia." | 7.79 | Incidence of bacteremia following upper gastrointestinal endoscopy and biopsy in healthy dogs before, during, and after treatment with omeprazole. ( Clark-Price, SC; Dossin, O; Jones, KR; Maddox, CW; Ridgway, MD, 2013) |
| "A double-blind study was conducted to compare gastric ulcer healing time in nontreated dogs with that in dogs treated with either cimetidine or omeprazole." | 7.68 | Comparison of effects of cimetidine and omeprazole on mechanically created gastric ulceration and on aspirin-induced gastritis in dogs. ( Bright, RM; DeNovo, RC; Jenkins, CC; Patton, CS; Rohrbach, BW, 1991) |
| "Gastroesophageal reflux was observed in 55% (11/20) of control dogs, 55% (11/20) of dogs receiving omeprazole once and 47% (7/15) of dogs receiving omeprazole twice." | 5.41 | Effect of two different pre-anaesthetic omeprazole protocols on gastroesophageal reflux incidence and pH in dogs. ( Boscan, P; Bryan, S; Fukushima, K; Krause, L; Lotti, F; Twedt, D; Vaca, C; Warrit, K, 2021) |
| " Although the number of cases treated with omeprazole are too few to draw firm conclusions, it would appear that proton pump inhibitors are useful and should be considered for cases of gastrinoma managed medically." | 4.83 | Canine gastrinoma: a case study and literature review of therapeutic options. ( Hughes, SM, 2006) |
| "To determine the incidence of bacteremia, as detected by routine methods for bacterial culture of blood samples, following routine endoscopic biopsy of the stomach and duodenum in healthy research dogs and to determine whether treatment with omeprazole administration affected the incidence of bacteremia." | 3.79 | Incidence of bacteremia following upper gastrointestinal endoscopy and biopsy in healthy dogs before, during, and after treatment with omeprazole. ( Clark-Price, SC; Dossin, O; Jones, KR; Maddox, CW; Ridgway, MD, 2013) |
| "A double-blind study was conducted to compare gastric ulcer healing time in nontreated dogs with that in dogs treated with either cimetidine or omeprazole." | 3.68 | Comparison of effects of cimetidine and omeprazole on mechanically created gastric ulceration and on aspirin-induced gastritis in dogs. ( Bright, RM; DeNovo, RC; Jenkins, CC; Patton, CS; Rohrbach, BW, 1991) |
| "Diarrhea was common (8/20 omeprazole, 5/17 placebo), hematochezia was rare (1/20 omeprazole, 1/17 placebo); melena was not observed." | 3.30 | Double-blinded placebo-controlled clinical trial of prophylactic omeprazole in dogs treated surgically for acute thoracolumbar intervertebral disc extrusion. ( Guadiano, P; Lewis, MJ; Mehra, JM; Moore, GE; Steiner, JM; Tolbert, MK, 2023) |
| "Omeprazole was not helpful in reducing the frequency or severity of GI AEs and was associated with more frequent and severer GI AEs in dogs with cancer treated with single agent piroxicam." | 3.01 | A prospective, randomized, placebo-controlled, double-blinded clinical trial comparing the incidence and severity of gastrointestinal adverse events in dogs with cancer treated with piroxicam alone or in combination with omeprazole or famotidine. ( Fulkerson, CM; Moore, GE; Shaevitz, MH, 2021) |
| " Reviewing the manner of administration and stated indications for use of both drugs, we find omeprazole is often administered outside dosing recommendations, and both drugs are frequently administered for aims that are unlikely to be achieved when considering their known biological effects in dogs." | 1.56 | Prospective observational study of the use of omeprazole and maropitant citrate in veterinary specialist care. ( Glanemann, B; McCormack, R; Olley, L; Swann, JW, 2020) |
| "The 3-year incidence of gastro-oesophageal reflux disease was 0·9% of our referral dog population." | 1.46 | Gastro-oesophageal reflux disease in 20 dogs (2012 to 2014). ( Hoerauf, A; Muenster, M; Vieth, M, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (14.29) | 18.2507 |
| 2000's | 3 (14.29) | 29.6817 |
| 2010's | 7 (33.33) | 24.3611 |
| 2020's | 8 (38.10) | 2.80 |
| Authors | Studies |
|---|---|
| Meinke, PT | 1 |
| Mehra, JM | 1 |
| Tolbert, MK | 3 |
| Guadiano, P | 1 |
| Steiner, JM | 2 |
| Moore, GE | 2 |
| Lewis, MJ | 1 |
| Rak, MB | 1 |
| Moyers, TD | 1 |
| Price, JM | 1 |
| Whittemore, JC | 1 |
| Weingart, C | 1 |
| Kohn, B | 1 |
| Jones, SM | 1 |
| Gaier, A | 1 |
| Enomoto, H | 1 |
| Ishii, P | 1 |
| Pilla, R | 1 |
| Price, J | 1 |
| Suchodolski, J | 1 |
| Papich, MG | 1 |
| Messenger, K | 1 |
| McCormack, R | 1 |
| Olley, L | 1 |
| Glanemann, B | 1 |
| Swann, JW | 1 |
| Cerri, S | 1 |
| Taminiau, B | 1 |
| de Lusancay, AH | 1 |
| Lecoq, L | 1 |
| Amory, H | 1 |
| Daube, G | 1 |
| Cesarini, C | 1 |
| Lotti, F | 1 |
| Twedt, D | 1 |
| Warrit, K | 1 |
| Bryan, S | 1 |
| Vaca, C | 1 |
| Krause, L | 1 |
| Fukushima, K | 1 |
| Boscan, P | 1 |
| Shaevitz, MH | 1 |
| Fulkerson, CM | 1 |
| Poirier-Guay, MP | 1 |
| Bélanger, MC | 1 |
| Frank, D | 1 |
| Hardy, BT | 1 |
| Gentile-Solomon, J | 1 |
| Solomon, JA | 1 |
| Lane, MB | 1 |
| Larson, JC | 1 |
| Stokes, JE | 1 |
| Muenster, M | 1 |
| Hoerauf, A | 1 |
| Vieth, M | 1 |
| Ellis, AE | 1 |
| Brown, CA | 1 |
| Miller, DL | 1 |
| Owens, SL | 1 |
| Parnell, NK | 1 |
| Jones, KR | 1 |
| Maddox, CW | 1 |
| Ridgway, MD | 1 |
| Clark-Price, SC | 1 |
| Dossin, O | 1 |
| Poncet, CM | 1 |
| Dupre, GP | 1 |
| Freiche, VG | 1 |
| Bouvy, BM | 1 |
| Hughes, SM | 1 |
| Colin-Jones, D | 1 |
| Altschul, M | 1 |
| Simpson, KW | 1 |
| Dykes, NL | 1 |
| Mauldin, EA | 1 |
| Reubi, JC | 1 |
| Cummings, JF | 1 |
| Jenkins, CC | 1 |
| DeNovo, RC | 1 |
| Patton, CS | 1 |
| Bright, RM | 1 |
| Rohrbach, BW | 1 |
2 reviews available for omeprazole and Canine Diseases
| Article | Year |
|---|---|
Perspectives in animal health: old targets and new opportunities.
Topics: Animals; Anthelmintics; Anti-Inflammatory Agents, Non-Steroidal; Anti-Obesity Agents; Anti-Ulcer Age | 2001 |
Canine gastrinoma: a case study and literature review of therapeutic options.
Topics: Animals; Anti-Ulcer Agents; Antineoplastic Agents; Dog Diseases; Dogs; Fatal Outcome; Female; Gastri | 2006 |
5 trials available for omeprazole and Canine Diseases
| Article | Year |
|---|---|
Double-blinded placebo-controlled clinical trial of prophylactic omeprazole in dogs treated surgically for acute thoracolumbar intervertebral disc extrusion.
Topics: Animals; Diarrhea; Dog Diseases; Dogs; Gastrointestinal Hemorrhage; Intervertebral Disc; Interverteb | 2023 |
Clinicopathologic and gastrointestinal effects of administration of prednisone, prednisone with omeprazole, or prednisone with probiotics to dogs: A double-blind randomized trial.
Topics: Animals; Dog Diseases; Dogs; Double-Blind Method; Gastrointestinal Hemorrhage; Glucocorticoids; Omep | 2023 |
The effect of combined carprofen and omeprazole administration on gastrointestinal permeability and inflammation in dogs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Dog Diseases; Dogs; Female; Inflammati | 2020 |
Effect of two different pre-anaesthetic omeprazole protocols on gastroesophageal reflux incidence and pH in dogs.
Topics: Anesthetics; Animals; Dog Diseases; Dogs; Female; Gastroesophageal Reflux; Hydrogen-Ion Concentratio | 2021 |
A prospective, randomized, placebo-controlled, double-blinded clinical trial comparing the incidence and severity of gastrointestinal adverse events in dogs with cancer treated with piroxicam alone or in combination with omeprazole or famotidine.
Topics: Animals; Dog Diseases; Dogs; Famotidine; Incidence; Neoplasms; Omeprazole; Piroxicam; Prospective St | 2021 |
14 other studies available for omeprazole and Canine Diseases
| Article | Year |
|---|---|
What is your diagnosis? Blood smear from a thrombocytopenic dog.
Topics: Animals; Blood Platelets; Dog Diseases; Dogs; Doxycycline; Fluid Therapy; Male; Megakaryocytes; Omep | 2020 |
Prospective observational study of the use of omeprazole and maropitant citrate in veterinary specialist care.
Topics: Animals; Dog Diseases; Dogs; Drug Prescriptions; Gastrointestinal Diseases; Hospitalization; Omepraz | 2020 |
Effect of oral administration of omeprazole on the microbiota of the gastric glandular mucosa and feces of healthy horses.
Topics: Administration, Oral; Animals; Dog Diseases; Dogs; Feces; Gastric Mucosa; Horse Diseases; Horses; Mi | 2020 |
Star gazing in a dog: atypical manifestation of upper gastrointestinal disease.
Topics: Animals; Diagnosis, Differential; Dog Diseases; Dogs; Female; Gastritis; Omeprazole; Stereotyped Beh | 2014 |
Multiple gastric erosions diagnosed by means of capsule endoscopy in a dog.
Topics: Animals; Anti-Ulcer Agents; Capsule Endoscopes; Dog Diseases; Dogs; Female; Omeprazole; Stomach Ulce | 2016 |
Continuous radiotelemetric monitoring of intragastric pH in a dog with peptic ulceration.
Topics: Animals; Anti-Ulcer Agents; Dog Diseases; Dogs; Drug Therapy, Combination; Hydrogen-Ion Concentratio | 2017 |
Gastro-oesophageal reflux disease in 20 dogs (2012 to 2014).
Topics: Animals; Dog Diseases; Dogs; Esophagoscopy; Female; Gastroesophageal Reflux; Male; Omeprazole | 2017 |
Diagnostic exercise: chronic vomiting in a dog.
Topics: Animals; Antiprotozoal Agents; Biopsy; Cryptosporidiosis; Cryptosporidium; Diagnosis, Differential; | 2010 |
What is the evidence? Portosystemic shunt in a dog.
Topics: Animals; Anti-Ulcer Agents; Diet; Dog Diseases; Dogs; Evidence-Based Medicine; Gastrointestinal Hemo | 2011 |
Incidence of bacteremia following upper gastrointestinal endoscopy and biopsy in healthy dogs before, during, and after treatment with omeprazole.
Topics: Animals; Bacteremia; Biopsy; Dog Diseases; Dogs; Duodenoscopy; Female; Gastroscopy; Incidence; Male; | 2013 |
Long-term results of upper respiratory syndrome surgery and gastrointestinal tract medical treatment in 51 brachycephalic dogs.
Topics: Airway Obstruction; Analysis of Variance; Animals; Anti-Ulcer Agents; Cisapride; Dog Diseases; Dogs; | 2006 |
Safety of omeprazole and lansoprazole.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Dog Diseases; Dogs; Lansoprazol | 1994 |
Evaluation of somatostatin analogues for the detection and treatment of gastrinoma in a dog.
Topics: Animals; Anti-Ulcer Agents; Antineoplastic Agents, Hormonal; Dog Diseases; Dogs; Dose-Response Relat | 1997 |
Comparison of effects of cimetidine and omeprazole on mechanically created gastric ulceration and on aspirin-induced gastritis in dogs.
Topics: Administration, Oral; Animals; Aspirin; Cimetidine; Dog Diseases; Dogs; Double-Blind Method; Gastrit | 1991 |