omeprazole has been researched along with Bile Reflux in 6 studies
Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.
Bile Reflux: Retrograde bile flow. Reflux of bile can be from the duodenum to the stomach (DUODENOGASTRIC REFLUX); to the esophagus (GASTROESOPHAGEAL REFLUX); or to the PANCREAS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate whether pantoprazole also reduces bile reflux and whether this is paralleled by a change in oesophageal motility." | 9.09 | Influence of pantoprazole on oesophageal motility, and bile and acid reflux in patients with oesophagitis. ( Brundler, R; Gaia, C; Gut, A; Halter, F; Inauen, W; Netzer, P, 2001) |
| " However, little is known about the effect of omeprazole on duodenogastric reflux (DGR) and duodenogastro-oesophageal reflux (DGOR)." | 9.08 | Effect of omeprazole 20 mg twice daily on duodenogastric and gastro-oesophageal bile reflux in Barrett's oesophagus. ( Anggiansah, A; Manifold, DK; Marshall, RE; Owen, WA; Owen, WJ, 1998) |
| "Twenty-nine children with moderate to severe erosive oesophagitis and abnormal oesophageal bile reflux were studied before and after treatment with omeprazole 1 mg/kg per day." | 7.73 | Treatment of oesophageal bile reflux in children: the results of a prospective study with omeprazole. ( Brecelj, J; Heuschkel, R; Homan, M; Orel, R, 2006) |
| "To investigate whether pantoprazole also reduces bile reflux and whether this is paralleled by a change in oesophageal motility." | 5.09 | Influence of pantoprazole on oesophageal motility, and bile and acid reflux in patients with oesophagitis. ( Brundler, R; Gaia, C; Gut, A; Halter, F; Inauen, W; Netzer, P, 2001) |
| " However, little is known about the effect of omeprazole on duodenogastric reflux (DGR) and duodenogastro-oesophageal reflux (DGOR)." | 5.08 | Effect of omeprazole 20 mg twice daily on duodenogastric and gastro-oesophageal bile reflux in Barrett's oesophagus. ( Anggiansah, A; Manifold, DK; Marshall, RE; Owen, WA; Owen, WJ, 1998) |
| "Twenty-nine children with moderate to severe erosive oesophagitis and abnormal oesophageal bile reflux were studied before and after treatment with omeprazole 1 mg/kg per day." | 3.73 | Treatment of oesophageal bile reflux in children: the results of a prospective study with omeprazole. ( Brecelj, J; Heuschkel, R; Homan, M; Orel, R, 2006) |
| " The aim of the present study was to investigate the pathogenesis of these gastric ulcers and to examine the effects of two antiulcer drugs; a proton pump inhibitor (2{[4-(3-methoxypropoxy)-3-methylpyridine-2-yl]methyl-sulfinyl}-1H -benzimidazole sodium salt, rabeprazole) and a mucosal protective drug (geranylgeranylacetone, GGA), on the gastric ulcers." | 3.70 | Bile reflux due to disturbed gastric movement is a cause of spontaneous gastric ulcer in W/Wv mice. ( Azuma, T; Dojyo, M; Ito, S; Ito, Y; Kato, T; Kohli, Y; Kuriyama, M; Miyaji, H; Suto, H; Yamazaki, Y, 1999) |
| "Both acid and bile reflux is significantly suppressed by proton pump inhibitor therapy with exceptions among individual esophagitis patients." | 1.31 | Increased acid and bile reflux in Barrett's esophagus compared to reflux esophagitis, and effect of proton pump inhibitor therapy. ( Menges, M; Müller, M; Zeitz, M, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Basu, KK | 1 |
| Pick, B | 1 |
| Bale, R | 1 |
| West, KP | 1 |
| de Caestecker, JS | 1 |
| Orel, R | 1 |
| Brecelj, J | 1 |
| Homan, M | 1 |
| Heuschkel, R | 1 |
| Marshall, RE | 1 |
| Anggiansah, A | 1 |
| Manifold, DK | 1 |
| Owen, WA | 1 |
| Owen, WJ | 1 |
| Azuma, T | 1 |
| Dojyo, M | 1 |
| Ito, S | 1 |
| Yamazaki, Y | 1 |
| Miyaji, H | 1 |
| Ito, Y | 1 |
| Suto, H | 1 |
| Kuriyama, M | 1 |
| Kato, T | 1 |
| Kohli, Y | 1 |
| Menges, M | 1 |
| Müller, M | 1 |
| Zeitz, M | 1 |
| Netzer, P | 1 |
| Gut, A | 1 |
| Brundler, R | 1 |
| Gaia, C | 1 |
| Halter, F | 1 |
| Inauen, W | 1 |
2 trials available for omeprazole and Bile Reflux
| Article | Year |
|---|---|
Effect of omeprazole 20 mg twice daily on duodenogastric and gastro-oesophageal bile reflux in Barrett's oesophagus.
Topics: Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Barrett Esophagus; Bile Reflux; Bilirubin; Drug A | 1998 |
Influence of pantoprazole on oesophageal motility, and bile and acid reflux in patients with oesophagitis.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Benzimid | 2001 |
4 other studies available for omeprazole and Bile Reflux
| Article | Year |
|---|---|
Efficacy and one year follow up of argon plasma coagulation therapy for ablation of Barrett's oesophagus: factors determining persistence and recurrence of Barrett's epithelium.
Topics: Adult; Aged; Aged, 80 and over; Barrett Esophagus; Bile Reflux; Esophagus; Follow-Up Studies; Humans | 2002 |
Treatment of oesophageal bile reflux in children: the results of a prospective study with omeprazole.
Topics: Adolescent; Anti-Ulcer Agents; Bile Reflux; Child; Child, Preschool; Esophagitis; Female; Gastroesop | 2006 |
Bile reflux due to disturbed gastric movement is a cause of spontaneous gastric ulcer in W/Wv mice.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Animals; Anti-Ulcer Agents; Benzimida | 1999 |
Increased acid and bile reflux in Barrett's esophagus compared to reflux esophagitis, and effect of proton pump inhibitor therapy.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Barrett Esophagus; Benzimidazoles; Bile Reflux; Case-Contro | 2001 |