omeprazole has been researched along with Aura in 3 studies
Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Toxic epidermal necrolysis (TEN) and Stevens-Johnson syndrome (SJS) have been associated with some drugs, particularly anticonvulsants such as phenytoin." | 3.74 | [Toxic epidermal necrolysis induced by phenytoin and whole brain radiotherapy]. ( Fernández, FA; Garcés, FJ; Pintor, E; Quesada, R, 2007) |
| "Omeprazole was given as a single oral dose before and after 3 weeks of treatment of five patients with CBZ (400-600 mg daily)." | 2.68 | Carbamazepine treatment induces the CYP3A4 catalysed sulphoxidation of omeprazole, but has no or less effect on hydroxylation via CYP2C19. ( Bertilsson, L; Chang, M; Tomson, T; Tybring, G; Widén, J, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fernández, FA | 1 |
| Pintor, E | 1 |
| Quesada, R | 1 |
| Garcés, FJ | 1 |
| Bertilsson, L | 1 |
| Tybring, G | 1 |
| Widén, J | 1 |
| Chang, M | 1 |
| Tomson, T | 1 |
| Andersson, T | 1 |
| Lagerström, PO | 1 |
| Unge, P | 1 |
1 trial available for omeprazole and Aura
| Article | Year |
|---|---|
Carbamazepine treatment induces the CYP3A4 catalysed sulphoxidation of omeprazole, but has no or less effect on hydroxylation via CYP2C19.
Topics: Adult; Aged; Anticonvulsants; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Cytoch | 1997 |
2 other studies available for omeprazole and Aura
| Article | Year |
|---|---|
[Toxic epidermal necrolysis induced by phenytoin and whole brain radiotherapy].
Topics: Adenocarcinoma; Aged; Anticonvulsants; Brain Neoplasms; Breast Neoplasms; Combined Modality Therapy; | 2007 |
A study of the interaction between omeprazole and phenytoin in epileptic patients.
Topics: Adult; Drug Interactions; Epilepsy; Female; Humans; Male; Middle Aged; Omeprazole; Phenytoin; Time F | 1990 |