Page last updated: 2024-11-01

omeprazole and Atresia, Esophageal

omeprazole has been researched along with Atresia, Esophageal in 4 studies

Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.

Research Excerpts

ExcerptRelevanceReference
"Omeprazole is a proton pump inhibitor that is used in acid suppression therapy in infants."6.94Rectal Omeprazole in Infants With Gastroesophageal Reflux Disease: A Randomized Pilot Trial. ( Bestebreurtje, P; de Koning, BAE; de Wildt, SN; Knibbe, CAJ; Plötz, FB; Roeleveld, N; Tibboel, D; van de Ven, CP; van Groen, B, 2020)
"Effective treatment of the esophagitis and prevention of stenosis consisted in high doses of omeprazole (1."5.31High-dose omeprazole in esophagitis with stenosis after surgical treatment of esophageal atresia. ( Kerremans, I; Robberecht, E; Van Biervliet, S; Van Winckel, M, 2001)
"Omeprazole is a proton pump inhibitor that is used in acid suppression therapy in infants."2.94Rectal Omeprazole in Infants With Gastroesophageal Reflux Disease: A Randomized Pilot Trial. ( Bestebreurtje, P; de Koning, BAE; de Wildt, SN; Knibbe, CAJ; Plötz, FB; Roeleveld, N; Tibboel, D; van de Ven, CP; van Groen, B, 2020)
"Effective treatment of the esophagitis and prevention of stenosis consisted in high doses of omeprazole (1."1.31High-dose omeprazole in esophagitis with stenosis after surgical treatment of esophageal atresia. ( Kerremans, I; Robberecht, E; Van Biervliet, S; Van Winckel, M, 2001)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Mitchell, TK1
Hall, NJ1
Yardley, I1
Cole, C1
Hardy, P1
King, A1
Murray, D1
Nuthall, E1
Roehr, C1
Stanbury, K1
Williams, R1
Pearce, J1
Woolfall, K1
Bestebreurtje, P1
de Koning, BAE1
Roeleveld, N1
Knibbe, CAJ1
Tibboel, D1
van Groen, B1
van de Ven, CP1
Plötz, FB1
de Wildt, SN1
Van Biervliet, S1
Van Winckel, M1
Robberecht, E1
Kerremans, I1
Sheth, NP1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Rectal and Oral Omeprazole Treatment of Gastroesophageal Reflux in Infants With Esophageal Atresia or Congenital Diaphragmatic Hernia; A Pharmacodynamic and Pharmacokinetic Study.[NCT00226044]Phase 317 participants (Actual)Interventional2005-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for omeprazole and Atresia, Esophageal

ArticleYear
Rectal Omeprazole in Infants With Gastroesophageal Reflux Disease: A Randomized Pilot Trial.
    European journal of drug metabolism and pharmacokinetics, 2020, Volume: 45, Issue:5

    Topics: Administration, Oral; Administration, Rectal; Esophageal Atresia; Esophageal pH Monitoring; Female;

2020

Other Studies

3 other studies available for omeprazole and Atresia, Esophageal

ArticleYear
Mixed-methods feasibility study to inform a randomised controlled trial of proton pump inhibitors to reduce strictures following neonatal surgery for oesophageal atresia.
    BMJ open, 2023, 04-20, Volume: 13, Issue:4

    Topics: Adult; Attitude of Health Personnel; Chemoprevention; Constriction, Pathologic; Esophageal Atresia;

2023
High-dose omeprazole in esophagitis with stenosis after surgical treatment of esophageal atresia.
    Journal of pediatric surgery, 2001, Volume: 36, Issue:9

    Topics: Digestive System Surgical Procedures; Dose-Response Relationship, Drug; Enzyme Inhibitors; Esophagea

2001
High dose Omeprazole in esophagitis with stenosis after surgical treatment of esophageal atresia.
    Journal of pediatric surgery, 2002, Volume: 37, Issue:6

    Topics: Esophageal Atresia; Esophageal Stenosis; Esophagitis; Gastroesophageal Reflux; Humans; Omeprazole

2002