Page last updated: 2024-11-01

omeprazole and Antibiotic-Associated Colitis

omeprazole has been researched along with Antibiotic-Associated Colitis in 7 studies

Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.

Research Excerpts

ExcerptRelevanceReference
"A 38-year-old Caucasian man with mild hypertension and no other significant medical history developed profound erectile dysfunction within 2 days of initiating over-the-counter omeprazole therapy, with erectile function rapidly normalizing following discontinuation of the drug."8.02Abrupt-onset, profound erectile dysfunction in a healthy young man after initiating over-the-counter omeprazole: a case report. ( Perry, TW, 2021)
"A 38-year-old Caucasian man with mild hypertension and no other significant medical history developed profound erectile dysfunction within 2 days of initiating over-the-counter omeprazole therapy, with erectile function rapidly normalizing following discontinuation of the drug."4.02Abrupt-onset, profound erectile dysfunction in a healthy young man after initiating over-the-counter omeprazole: a case report. ( Perry, TW, 2021)
"We describe a 54-year-old man with Helicobacter pylori (+) duodenal ulcer who developed Clostridium difficile associated colitis, 5 days after commencing a 'triple' regimen consisting of omeprazole 20 mg b."3.70Clostridium difficile colitis associated with a 'triple' regimen, containing clarithromycin and metronidazole, to eradicate Helicobacter pylori. ( Archimandritis, A; Katsorida, M; Souyioultzis, S; Tzivras, M, 1998)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's3 (42.86)29.6817
2010's1 (14.29)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Perry, TW1
Freedberg, DE1
Toussaint, NC1
Chen, SP1
Ratner, AJ1
Whittier, S1
Wang, TC1
Wang, HH1
Abrams, JA1
Rai, R1
Rai, S1
Kubo, N1
Kochi, S1
Ariyama, I1
Murata, M1
Furusyo, N1
Hayashi, J1
Schweigart, U1
Franck, H1
Schepp, W1
Lehn, N1
Becker, K1
Classen, M1
Archimandritis, A1
Souyioultzis, S1
Katsorida, M1
Tzivras, M1
Lau, CF1
Hui, PK1
Fung, TT1
Tung, SY1
Wong, AM1
Loo, CK1
Lam, KM1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effects of Gastric Acid Suppression on the Colonic Microbiome[NCT01901276]Phase 412 participants (Actual)Interventional2013-08-31Completed
Factors Influencing the Human Gut Microbiome Profile in Multi-ethnic Groups of the Singapore Community (FAMES)[NCT02893709]36 participants (Actual)Interventional2015-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for omeprazole and Antibiotic-Associated Colitis

ArticleYear
Proton Pump Inhibitors Alter Specific Taxa in the Human Gastrointestinal Microbiome: A Crossover Trial.
    Gastroenterology, 2015, Volume: 149, Issue:4

    Topics: Bacteria; Clostridioides difficile; Cross-Over Studies; Drug Administration Schedule; Enterocolitis,

2015
Proton Pump Inhibitors Alter Specific Taxa in the Human Gastrointestinal Microbiome: A Crossover Trial.
    Gastroenterology, 2015, Volume: 149, Issue:4

    Topics: Bacteria; Clostridioides difficile; Cross-Over Studies; Drug Administration Schedule; Enterocolitis,

2015
Proton Pump Inhibitors Alter Specific Taxa in the Human Gastrointestinal Microbiome: A Crossover Trial.
    Gastroenterology, 2015, Volume: 149, Issue:4

    Topics: Bacteria; Clostridioides difficile; Cross-Over Studies; Drug Administration Schedule; Enterocolitis,

2015
Proton Pump Inhibitors Alter Specific Taxa in the Human Gastrointestinal Microbiome: A Crossover Trial.
    Gastroenterology, 2015, Volume: 149, Issue:4

    Topics: Bacteria; Clostridioides difficile; Cross-Over Studies; Drug Administration Schedule; Enterocolitis,

2015

Other Studies

6 other studies available for omeprazole and Antibiotic-Associated Colitis

ArticleYear
Abrupt-onset, profound erectile dysfunction in a healthy young man after initiating over-the-counter omeprazole: a case report.
    Journal of medical case reports, 2021, Jul-24, Volume: 15, Issue:1

    Topics: Adult; Aged; Enterocolitis, Pseudomembranous; Erectile Dysfunction; Humans; Male; Omeprazole; Proton

2021
Pseudomembranous colitis requiring surgical intervention following triple therapy for Helicobacter pylori eradication.
    ANZ journal of surgery, 2002, Volume: 72, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Clarithromycin; Drug Therapy, Combination; Enterocol

2002
[Pseudomembranous colitis after Helicobacter pylori eradication therapy].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 2006, Volume: 80, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Ag

2006
[Toxic megacolon after Helicobacter pylori eradication therapy].
    Der Internist, 1997, Volume: 38, Issue:4

    Topics: Aged; Amoxicillin; Anti-Ulcer Agents; Colon; Diagnosis, Differential; Drug Therapy, Combination; Ent

1997
Clostridium difficile colitis associated with a 'triple' regimen, containing clarithromycin and metronidazole, to eradicate Helicobacter pylori.
    Journal of internal medicine, 1998, Volume: 243, Issue:3

    Topics: Anti-Ulcer Agents; Clarithromycin; Drug Therapy, Combination; Duodenal Ulcer; Enterocolitis, Pseudom

1998
Pseudomembranous colitis without diarrhoea following Helicobacter pylori eradication therapy.
    Hospital medicine (London, England : 1998), 2001, Volume: 62, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents

2001