Page last updated: 2024-11-01

omeprazole and Angina Pectoris

omeprazole has been researched along with Angina Pectoris in 7 studies

Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.

Angina Pectoris: The symptom of paroxysmal pain consequent to MYOCARDIAL ISCHEMIA usually of distinctive character, location and radiation. It is thought to be provoked by a transient stressful situation during which the oxygen requirements of the MYOCARDIUM exceed that supplied by the CORONARY CIRCULATION.

Research Excerpts

ExcerptRelevanceReference
"To estimate the effect of double omeprazole dose on the course of angina pectoris and treadmill stress test in patients with coronary artery disease (CAD), using double-blind, crossover randomised, placebo-controlled study design."9.13The effect of double dose of omeprazole on the course of angina pectoris and treadmill stress test in patients with coronary artery disease--a randomised, double-blind, placebo controlled, crossover trial. ( Budzyński, J; Fabisiak, J; Kłopocka, M; Majer, M; Pulkowski, G; Suppan, K; Swiatkowski, M, 2008)
"To estimate the effect of double omeprazole dose on the course of angina pectoris and treadmill stress test in patients with coronary artery disease (CAD), using double-blind, crossover randomised, placebo-controlled study design."5.13The effect of double dose of omeprazole on the course of angina pectoris and treadmill stress test in patients with coronary artery disease--a randomised, double-blind, placebo controlled, crossover trial. ( Budzyński, J; Fabisiak, J; Kłopocka, M; Majer, M; Pulkowski, G; Suppan, K; Swiatkowski, M, 2008)
" The aim of this study was to estimate the effects of gastric acid output suppression with rabeprazole on course of angina pectoris and results of the treadmill stress test in patients with CAD."5.11Suppression of gastric acid production may improve the course of angina pectoris and the results of treadmill stress test in patients with coronary artery disease. ( Budzyński, J; Fabisiak, J; Kłopocka, M; Majer, M; Morawski, W; Pulkowski, G; Suppan, K; Swiatkowski, M, 2004)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (42.86)18.2507
2000's3 (42.86)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Budzyński, J3
Pulkowski, G3
Suppan, K3
Fabisiak, J3
Majer, M3
Kłopocka, M3
Galus-Pulkowska, B1
Wasielewski, M1
Swiatkowski, M2
Morawski, W1
Thumshirn, M1
Kajinami, K1
Mabuchi, H1
Sipilä, J1
Parkkola, R1
Varpula, M1
Achem, SR1
DeVault, KR1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Non-cardiac Chest Pain Evaluation and Treatment Study (CARPA) - Part 2: Treatment Study[NCT00462241]115 participants (Actual)Interventional2006-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for omeprazole and Angina Pectoris

ArticleYear
Recent developments in chest pain of undetermined origin.
    Current gastroenterology reports, 2000, Volume: 2, Issue:3

    Topics: Angina Pectoris; Anti-Ulcer Agents; Chest Pain; Diagnosis, Differential; Esophageal Diseases; Humans

2000

Trials

3 trials available for omeprazole and Angina Pectoris

ArticleYear
Improvement in health-related quality of life after therapy with omeprazole in patients with coronary artery disease and recurrent angina-like chest pain. A double-blind, placebo-controlled trial of the SF-36 survey.
    Health and quality of life outcomes, 2011, Sep-22, Volume: 9

    Topics: Adult; Aged; Angina Pectoris; Anti-Ulcer Agents; Coronary Angiography; Coronary Artery Disease; Cros

2011
Suppression of gastric acid production may improve the course of angina pectoris and the results of treadmill stress test in patients with coronary artery disease.
    Medical science monitor : international medical journal of experimental and clinical research, 2004, Volume: 10, Issue:9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Angina Pectoris; Anti-Ulcer Agents; Benzimidazoles; Comorbi

2004
The effect of double dose of omeprazole on the course of angina pectoris and treadmill stress test in patients with coronary artery disease--a randomised, double-blind, placebo controlled, crossover trial.
    International journal of cardiology, 2008, Jul-04, Volume: 127, Issue:2

    Topics: Analysis of Variance; Angina Pectoris; Anti-Ulcer Agents; Chest Pain; Coronary Disease; Cross-Over S

2008

Other Studies

3 other studies available for omeprazole and Angina Pectoris

ArticleYear
[A case from practice (316). Hiccups in grade I reflux esophagitis and hiatal hernia. Suspected coronary heart disease in NYHA II angina pectoris].
    Praxis, 1995, Jan-24, Volume: 84, Issue:4

    Topics: Aged; Aged, 80 and over; Angina Pectoris; Chest Pain; Coronary Disease; Diagnosis, Differential; Eso

1995
Omeprazole and diminished antianginal drug delivery.
    Annals of internal medicine, 1994, Sep-01, Volume: 121, Issue:5

    Topics: Angina Pectoris; Drug Therapy, Combination; Gastric Acid; Humans; Hydrogen-Ion Concentration; Male;

1994
[Esophagitis complicated with angina pectoris and mediastinitis].
    Duodecim; laaketieteellinen aikakauskirja, 1996, Volume: 112, Issue:19

    Topics: Angina Pectoris; Antacids; Diagnosis, Differential; Esophagitis; Esophagoscopy; Humans; Male; Medias

1996