Page last updated: 2024-11-01

omeprazole and Anaphylaxis

omeprazole has been researched along with Anaphylaxis in 23 studies

Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.

Anaphylaxis: An acute hypersensitivity reaction due to exposure to a previously encountered ANTIGEN. The reaction may include rapidly progressing URTICARIA, respiratory distress, vascular collapse, systemic SHOCK, and death.

Research Excerpts

ExcerptRelevanceReference
"To report a case of anaphylaxis to pantoprazole, that occurred in a patient admitted with gastrointestinal complaints."8.12Anaphylaxis to Pantoprazole: A Case Report and Prerequisite for Vigilant Prescribing Practises for Proton Pump Inhibitors. ( Begum, A; Fayaz, SH; James, J; Rani, J; Sathyanarayanan, V, 2022)
"To confirm the immediate-type mechanism of recurrent anaphylactic reactions to the repeated administration of omeprazole using skin testing and to enable safe administration of the drug after successful oral desensitization."7.73Anaphylaxis to omeprazole: diagnosis and desensitization protocol. ( Confino-Cohen, R; Goldberg, A, 2006)
"To report a new patient with omeprazole-induced anaphylaxis demonstrated by skin tests and increased serum tryptase levels."7.70Anaphylaxis to omeprazole. ( Borja, J; Cabrera, M; Feo, F; Galindo, PA; García, R; Gómez, E; Martínez, C, 1999)
"Omeprazole is a proton pump inhibitor which reduces both basal and stimulated gastric acid secretion by inhibiting the parietal cell enzyme H(+)-K(+)-adenosine triphosphatase."5.33[Anaphylaxis caused by omeprazole]. ( Bauer, C; Fackler, I; Kamann, S; Przybilla, B, 2006)
" We report 3 cases of anaphylactic reactions induced by lansoprazole or ranitidine diagnosed in a population of 8304 first-referral patients over a 13-year period."4.83Anaphylactic reaction to drugs commonly used for gastrointestinal system diseases: 3 case reports and review of the literature. ( Bozkurt, B; Demirkan, K; Kalyoncu, AF; Karakaya, G, 2006)
"To report a case of anaphylaxis to pantoprazole, that occurred in a patient admitted with gastrointestinal complaints."4.12Anaphylaxis to Pantoprazole: A Case Report and Prerequisite for Vigilant Prescribing Practises for Proton Pump Inhibitors. ( Begum, A; Fayaz, SH; James, J; Rani, J; Sathyanarayanan, V, 2022)
"To confirm the immediate-type mechanism of recurrent anaphylactic reactions to the repeated administration of omeprazole using skin testing and to enable safe administration of the drug after successful oral desensitization."3.73Anaphylaxis to omeprazole: diagnosis and desensitization protocol. ( Confino-Cohen, R; Goldberg, A, 2006)
"To report a new patient with omeprazole-induced anaphylaxis demonstrated by skin tests and increased serum tryptase levels."3.70Anaphylaxis to omeprazole. ( Borja, J; Cabrera, M; Feo, F; Galindo, PA; García, R; Gómez, E; Martínez, C, 1999)
"Additionally, cases of Kounis syndrome associated with lansoprazole and pantoprazole have been previously reported in the literature."1.91Unexpected cause of Kounis syndrome: hypersensitivity reaction to omeprazole. ( Çınar, T; Erdem, A; Kılıç, Ş; Öztürk, NB, 2023)
"Although rare, anaphylactic reactions induced by proton pump inhibitors have been reported."1.35Nine cases of omeprazole allergy: cross-reactivity between proton pump inhibitors. ( Alarcón, E; Blasco, A; Del Pozo, MD; Escudero, R; González, I; Lobera, T; Navarro, B; Venturini, M, 2009)
"Omeprazole is a proton pump inhibitor which reduces both basal and stimulated gastric acid secretion by inhibiting the parietal cell enzyme H(+)-K(+)-adenosine triphosphatase."1.33[Anaphylaxis caused by omeprazole]. ( Bauer, C; Fackler, I; Kamann, S; Przybilla, B, 2006)
"To report two cases of anaphylactic reactions to proton-pump inhibitors (PPIs)."1.31Anaphylactic reactions to proton-pump inhibitors. ( Mees, EB; Meyboom, RH; Natsch, S; Vinks, MH; Voogt, AK, 2000)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (8.70)18.2507
2000's16 (69.57)29.6817
2010's3 (13.04)24.3611
2020's2 (8.70)2.80

Authors

AuthorsStudies
Erdem, A1
Çınar, T1
Kılıç, Ş1
Öztürk, NB1
James, J1
Rani, J1
Sathyanarayanan, V1
Begum, A1
Fayaz, SH1
Dohr, J1
Hunzelmann, N1
Brown, A1
Treudler, R1
Reuter, A1
Engin, AM1
Simon, JC1
González-Rubio, F1
Esteban-Jiménez, O1
Garcés-Sotillos, MD1
Colás-Sanz, C1
Stefanaki, EC1
Vovolis, V2
Letsa, I1
Koutsostathis, N2
Stefanaki, E1
Lobera, T1
Navarro, B1
Del Pozo, MD1
González, I1
Blasco, A1
Escudero, R1
Venturini, M1
Alarcón, E1
Dueñas-Laita, A1
Pineda, F1
Armentia, A1
Fardet, L2
Izzedine, H2
Ciroldi, M2
Tiev, KP2
Cabane, J2
Muela Molinero, A1
Ballesteros del Río, B1
Nistal de Paz, F1
Fernandez Pérez, E1
Ricciardi, L1
Fedele, R1
Mazzeo, L1
Saitta, S1
Mancuso, V1
Isola, S1
Kollmeier, AP1
Eddleston, J1
Zuraw, BL1
Christiansen, SC1
Gratacós, L1
Soy, D1
Lluís, M1
López, B1
Nicolás, JM1
Codina, C1
Nogué, S1
Ribas, J1
Kamann, S1
Bauer, C1
Fackler, I1
Przybilla, B1
Confino-Cohen, R1
Goldberg, A1
Demirkan, K1
Bozkurt, B1
Karakaya, G1
Kalyoncu, AF1
Reyes Balaguer, J1
Campos Andreu, A1
Hernández Fernández de Rojas, D1
Ottervanger, JP1
Phaff, RA1
Vermeulen, EG1
Stricker, BH1
Galindo, PA1
Borja, J1
Feo, F1
Gómez, E1
García, R1
Cabrera, M1
Martínez, C1
Natsch, S1
Vinks, MH1
Voogt, AK1
Mees, EB1
Meyboom, RH1
Kaatz, M1
Bauer, A1
Hipler, C1
Elsner, P1

Reviews

1 review available for omeprazole and Anaphylaxis

ArticleYear
Anaphylactic reaction to drugs commonly used for gastrointestinal system diseases: 3 case reports and review of the literature.
    Journal of investigational allergology & clinical immunology, 2006, Volume: 16, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anaphylaxis; Anti-Ulcer Agents; Benzimidazoles; Famotidine;

2006

Other Studies

22 other studies available for omeprazole and Anaphylaxis

ArticleYear
Unexpected cause of Kounis syndrome: hypersensitivity reaction to omeprazole.
    BMJ case reports, 2023, Oct-24, Volume: 16, Issue:10

    Topics: Anaphylaxis; Humans; Kounis Syndrome; Omeprazole; Proton Pump Inhibitors

2023
Anaphylaxis to Pantoprazole: A Case Report and Prerequisite for Vigilant Prescribing Practises for Proton Pump Inhibitors.
    Current drug safety, 2022, Volume: 17, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anaphylaxis; Female; Humans; Omeprazole; Pantoprazole

2022
[Immediate type reactions to proton pump inhibitors using pantoprazole and omeprazole as examples].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2018, Volume: 69, Issue:2

    Topics: Administration, Oral; Anaphylaxis; Cross Reactions; Drug Eruptions; Drug Hypersensitivity; Female; H

2018
A Case of Anaphylaxis After Garlic Ingestion: Is Alliinase the Only Culprit Allergen?
    Journal of investigational allergology & clinical immunology, 2015, Volume: 25, Issue:5

    Topics: Anaphylaxis; Carbon-Sulfur Lyases; Food Hypersensitivity; Garlic; Gastroesophageal Reflux; Humans; M

2015
Anaphylactic shock due to omeprazole.
    Gastroenterologia y hepatologia, 2017, Volume: 40, Issue:1

    Topics: Anaphylaxis; Humans; Male; Middle Aged; Omeprazole; Proton Pump Inhibitors

2017
Anaphylactic reaction to omeprazole.
    The American journal of gastroenterology, 2008, Volume: 103, Issue:6

    Topics: Adult; Anaphylaxis; Anti-Ulcer Agents; Female; Humans; Omeprazole

2008
IgE-mediated anaphylaxis to proton pump inhibitors - cross-reacting study.
    Allergy, 2008, Volume: 63, Issue:9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anaphylaxis; Female; Humans; Immunoglobulin E; Male;

2008
Nine cases of omeprazole allergy: cross-reactivity between proton pump inhibitors.
    Journal of investigational allergology & clinical immunology, 2009, Volume: 19, Issue:1

    Topics: Adult; Anaphylaxis; Cross Reactions; Drug Hypersensitivity; Female; Humans; Middle Aged; Omeprazole;

2009
Hypersensitivity to generic drugs with soybean oil.
    The New England journal of medicine, 2009, Sep-24, Volume: 361, Issue:13

    Topics: Aged, 80 and over; Anaphylaxis; Capsules; Drugs, Generic; Excipients; Female; Humans; Immunoglobulin

2009
Pantoprazole-induced recurrent anaphylactic shock.
    The American journal of gastroenterology, 2002, Volume: 97, Issue:11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anaphylaxis; Anti-Ulcer Agents; Benzimidazoles; Enzy

2002
[Inmediate antphylactic shock after the administration of intravenous omeprazol].
    Revista clinica espanola, 2003, Volume: 203, Issue:4

    Topics: Aged; Anaphylaxis; Anti-Ulcer Agents; Female; Gastritis; Heart Arrest; Humans; Injections, Intraveno

2003
Adverse reactions to pantoprazole.
    Scandinavian journal of gastroenterology, 2003, Volume: 38, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anaphylaxis; Benzimidazoles; Enzyme Inhibitors; Fema

2003
Recurrent anaphylaxis linked to pantoprazole.
    The Journal of allergy and clinical immunology, 2004, Volume: 114, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anaphylaxis; Anti-Ulcer Agents; Aryl Hydrocarbon Hydroxylas

2004
Apparent anaphylaxis associated with pantoprazole.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2005, Jul-01, Volume: 62, Issue:13

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anaphylaxis; Anti-Ulcer Agents; Benzimidazoles; Human

2005
[Anaphylaxis caused by omeprazole].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2006, Volume: 57, Issue:11

    Topics: Anaphylaxis; Angioedema; Anti-Ulcer Agents; Basophil Degranulation Test; Basophils; Drug Hypersensit

2006
Anaphylaxis to omeprazole: diagnosis and desensitization protocol.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2006, Volume: 96, Issue:1

    Topics: Adult; Anaphylaxis; Desensitization, Immunologic; Enzyme Inhibitors; Gastritis; Helicobacter Infecti

2006
[Anaphylaxis to proton pump inhibitors].
    Medicina clinica, 2007, May-26, Volume: 128, Issue:20

    Topics: Adolescent; Anaphylaxis; Female; Humans; Omeprazole; Proton Pump Inhibitors

2007
Anaphylaxis to omeprazole.
    The Journal of allergy and clinical immunology, 1996, Volume: 97, Issue:6

    Topics: Anaphylaxis; Drug Hypersensitivity; Humans; Male; Middle Aged; Omeprazole

1996
Anaphylaxis to omeprazole.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 1999, Volume: 82, Issue:1

    Topics: Adult; Anaphylaxis; Chymases; Humans; Immunoglobulin E; Inflammation Mediators; Intradermal Tests; M

1999
Anaphylactic reactions to proton-pump inhibitors.
    The Annals of pharmacotherapy, 2000, Volume: 34, Issue:4

    Topics: Anaphylaxis; Anti-Ulcer Agents; Female; Humans; Male; Middle Aged; Omeprazole; Peptic Ulcer; Proton

2000
Nonallergic anaphylaxis to pantoprazole.
    Allergy, 2002, Volume: 57, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anaphylaxis; Benzimidazoles; Diagnosis, Differential; Drug

2002
Pantoprazole-induced recurrent anaphylactic shock.
    The American journal of gastroenterology, 2002, Volume: 97, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anaphylaxis; Benzimidazoles; Esophagitis, Peptic; Hu

2002