omeprazole has been researched along with Alzheimer Disease in 3 studies
Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Hu, S | 1 |
| Huang, Y | 1 |
| Wu, YJ | 1 |
| He, H | 1 |
| Grant-Young, KA | 1 |
| Bertekap, RL | 1 |
| Whiterock, V | 1 |
| Brassil, P | 1 |
| Lentz, K | 1 |
| Sivaprakasam, P | 1 |
| Langley, DR | 1 |
| Westphal, RS | 1 |
| Scola, PM | 1 |
| Baidya, ATK | 1 |
| Das, B | 1 |
| Devi, B | 1 |
| Långström, B | 1 |
| Ågren, H | 1 |
| Darreh-Shori, T | 1 |
| Kumar, R | 1 |
| Kountouras, J | 1 |
| Boziki, M | 1 |
| Gavalas, E | 1 |
| Zavos, C | 1 |
| Grigoriadis, N | 1 |
| Deretzi, G | 1 |
| Tzilves, D | 1 |
| Katsinelos, P | 1 |
| Tsolaki, M | 1 |
| Chatzopoulos, D | 1 |
| Venizelos, I | 1 |
1 trial available for omeprazole and Alzheimer Disease
| Article | Year |
|---|---|
Eradication of Helicobacter pylori may be beneficial in the management of Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; B | 2009 |
2 other studies available for omeprazole and Alzheimer Disease
| Article | Year |
|---|---|
Structure activity relationship studies of 3-arylsulfonyl-pyrido[1,2-a]pyrimidin-4-imines as potent 5-HT₆ antagonists.
Topics: Alzheimer Disease; Animals; Humans; Imines; Molecular Docking Simulation; Rats; Receptors, Serotonin | 2014 |
Mechanistic Insight into the Inhibition of Choline Acetyltransferase by Proton Pump Inhibitors.
Topics: Alzheimer Disease; Choline O-Acetyltransferase; Cholinergic Agents; Humans; Omeprazole; Proton Pump | 2023 |