Page last updated: 2024-11-01

omeprazole and Adenoma

omeprazole has been researched along with Adenoma in 12 studies

Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.

Adenoma: A benign epithelial tumor with a glandular organization.

Research Excerpts

ExcerptRelevanceReference
"A total of 158 patients (155 early gastric cancers and three adenomas) were randomly assigned to the PPI group (omeprazole 20 mg/day) or H(2) RA group (famotidine 40 mg/day) in a prospective randomized controlled trial."5.16Prospective randomized controlled trial to compare the effects of omeprazole and famotidine in preventing delayed bleeding and promoting ulcer healing after endoscopic submucosal dissection. ( Fukui, H; Hori, K; Kim, Y; Kondo, T; Matsumoto, T; Miwa, H; Morita, T; Okugawa, T; Oshima, T; Sakurai, J; Tanaka, J; Tomita, T; Toyoshima, F; Watari, J; Yamasaki, T, 2012)
"Of 64 patients with an endoscopically diagnosed gastric adenoma and H pylori infection, 32 were treated with omeprazole and antibiotics to eradicate the infection, and 32 were not."5.09Effect of Helicobacter pylori eradication on malignant transformation of gastric adenoma. ( Arai, K; Kobayashi, R; Mori, M; Ohki, I; Saito, K, 2000)
"In our study, oral administration of omeprazole for 1 week was sufficient to achieve healing of ESD-induced artificial gastric ulcers."3.81Effective healing of endoscopic submucosal dissection-induced ulcers by a single week of proton pump inhibitor treatment: a retrospective study. ( Ando, T; Fujinami, H; Hosokawa, A; Kajiura, S; Mihara, H; Minemura, M; Nishikawa, J; Ogawa, K; Sugiyama, T; Ueda, A, 2015)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's7 (58.33)29.6817
2010's3 (25.00)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Madka, V1
Kumar, G1
Pathuri, G1
Panneerselvam, J1
Zhang, Y1
Ganta, V1
Lightfoot, S1
Lubet, R1
Suen, CS1
Steele, VE1
Janakiram, NB1
Mohammed, A1
Rao, CV1
Kajiura, S1
Hosokawa, A1
Ueda, A1
Mihara, H1
Ando, T1
Fujinami, H1
Nishikawa, J1
Ogawa, K1
Minemura, M1
Sugiyama, T1
Familiar, C1
Antón, T1
Moraga, I1
Ramos, A1
Marco, A1
Tomita, T1
Kim, Y1
Yamasaki, T1
Okugawa, T1
Kondo, T1
Toyoshima, F1
Sakurai, J1
Tanaka, J1
Morita, T1
Oshima, T1
Fukui, H1
Hori, K1
Watari, J1
Matsumoto, T1
Miwa, H1
Watson, SA2
Morris, TM1
McWilliams, DF1
Harris, J1
Evans, S1
Smith, A1
Clarke, PA1
Lee, SY1
Kim, JJ1
Lee, JH1
Kim, YH1
Rhee, PL1
Paik, SW1
Rhee, JC1
Kawamura, O1
Kusano, M1
Shimoyama, Y1
Horikoshi, T1
Sekiguchi, T1
Mori, M2
Gotoda, T1
Saito, D1
Kondo, H1
Ono, H1
Oda, I1
Fujishiro, M1
Yamaguchi, H1
Saito, K1
Arai, K1
Kobayashi, R1
Ohki, I1
Smith, AM1
McDonald, JM1
Longnecker, DS1
Bell, RH1
Sato, H1
Abe, K1
Oshima, N1
Kawashima, K1
Hamamoto, N1
Moritani, M1
Mak, R1
Ishihara, S1
Adachi, K1
Kawauchi, H1
Kinoshita, Y1

Reviews

1 review available for omeprazole and Adenoma

ArticleYear
[About a case of multiple endocrine neoplasia type 1. Review of some clinical manifestations and treatment controversies].
    Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2011, Volume: 58, Issue:2

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Carcinoid Tumor; Combined Modality Therapy; Duodenal Neopla

2011

Trials

4 trials available for omeprazole and Adenoma

ArticleYear
Prospective randomized controlled trial to compare the effects of omeprazole and famotidine in preventing delayed bleeding and promoting ulcer healing after endoscopic submucosal dissection.
    Journal of gastroenterology and hepatology, 2012, Volume: 27, Issue:9

    Topics: Adenocarcinoma; Adenoma; Aged; Aged, 80 and over; Analysis of Variance; Famotidine; Female; Gastric

2012
Healing rate of EMR-induced ulcer in relation to the duration of treatment with omeprazole.
    Gastrointestinal endoscopy, 2004, Volume: 60, Issue:2

    Topics: Adenoma; Aged; Anti-Ulcer Agents; Endoscopy, Gastrointestinal; Female; Humans; Male; Omeprazole; Pro

2004
Oral erythromycin accelerates impaired gastrointestinal motility after endoscopic mucosal resection.
    Digestive diseases and sciences, 2007, Volume: 52, Issue:9

    Topics: Adenoma; Administration, Oral; Adult; Aged; Dose-Response Relationship, Drug; Endoscopy, Gastrointes

2007
Effect of Helicobacter pylori eradication on malignant transformation of gastric adenoma.
    Gastrointestinal endoscopy, 2000, Volume: 52, Issue:1

    Topics: Adenoma; Aged; Aged, 80 and over; Amoxicillin; Carcinoma; Cell Transformation, Neoplastic; Clarithro

2000

Other Studies

7 other studies available for omeprazole and Adenoma

ArticleYear
Proton Pump Inhibitor Omeprazole Suppresses Carcinogen-induced Colonic Adenoma Progression to Adenocarcinoma in F344 Rat.
    Cancer prevention research (Philadelphia, Pa.), 2021, Volume: 14, Issue:11

    Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Omeprazole; Proton P

2021
Effective healing of endoscopic submucosal dissection-induced ulcers by a single week of proton pump inhibitor treatment: a retrospective study.
    BMC research notes, 2015, Apr-15, Volume: 8

    Topics: Adenocarcinoma; Adenoma; Aged; Anti-Ulcer Agents; Female; Gastric Mucosa; Gastroscopy; Humans; Male;

2015
Potential role of endocrine gastrin in the colonic adenoma carcinoma sequence.
    British journal of cancer, 2002, Aug-27, Volume: 87, Issue:5

    Topics: Adenocarcinoma; Adenoma; Animals; Colonic Neoplasms; Computer Systems; Enzyme Inhibitors; Female; Fi

2002
Endoscopic and histological reversibility of gastric adenoma after eradication of Helicobacter pylori.
    Journal of gastroenterology, 1999, Volume: 34 Suppl 11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenoma; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; A

1999
Hypergastrinemia promotes adenoma progression in the APC(Min-/+) mouse model of familial adenomatous polyposis.
    Cancer research, 2001, Jan-15, Volume: 61, Issue:2

    Topics: Adenoma; Adenomatous Polyposis Coli; Adenomatous Polyposis Coli Protein; Animals; Bromodeoxyuridine;

2001
Effect of hypergastrinemia on pancreatic carcinogenesis.
    American journal of surgery, 2002, Volume: 183, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenoma; Animals; Anti-Ulcer Agents; Azaserine; Carcinoma i

2002
Primary hyperparathyroidism with duodenal ulcer and H. pylori infection.
    Internal medicine (Tokyo, Japan), 2002, Volume: 41, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenoma; Aged; Anti-Ulcer Agents; Benzimidazoles; Duodenal

2002