Page last updated: 2024-11-01

omeprazole and Adenocarcinoma

omeprazole has been researched along with Adenocarcinoma in 62 studies

Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.

Adenocarcinoma: A malignant epithelial tumor with a glandular organization.

Research Excerpts

ExcerptRelevanceReference
"A total of 158 patients (155 early gastric cancers and three adenomas) were randomly assigned to the PPI group (omeprazole 20 mg/day) or H(2) RA group (famotidine 40 mg/day) in a prospective randomized controlled trial."5.16Prospective randomized controlled trial to compare the effects of omeprazole and famotidine in preventing delayed bleeding and promoting ulcer healing after endoscopic submucosal dissection. ( Fukui, H; Hori, K; Kim, Y; Kondo, T; Matsumoto, T; Miwa, H; Morita, T; Okugawa, T; Oshima, T; Sakurai, J; Tanaka, J; Tomita, T; Toyoshima, F; Watari, J; Yamasaki, T, 2012)
" pylori infection, indomethacin and their combination affects the healing of gastric ulcers and whether or not such factors provoke a relapse of healed acetic acid ulcers; and 2) whether or not eradication of the bacteria with drugs at specified times after infection prevents the development of mucosal changes, including gastric adenocarcinoma."4.81[Pharmacological study on the pathological changes of the gastric mucosa in Helicobacter pylori-infected Mongolian gerbils]. ( Ebata, M; Keto, Y; Okabe, S, 2001)
"In our study, oral administration of omeprazole for 1 week was sufficient to achieve healing of ESD-induced artificial gastric ulcers."3.81Effective healing of endoscopic submucosal dissection-induced ulcers by a single week of proton pump inhibitor treatment: a retrospective study. ( Ando, T; Fujinami, H; Hosokawa, A; Kajiura, S; Mihara, H; Minemura, M; Nishikawa, J; Ogawa, K; Sugiyama, T; Ueda, A, 2015)
"Toxic epidermal necrolysis (TEN) and Stevens-Johnson syndrome (SJS) have been associated with some drugs, particularly anticonvulsants such as phenytoin."3.74[Toxic epidermal necrolysis induced by phenytoin and whole brain radiotherapy]. ( Fernández, FA; Garcés, FJ; Pintor, E; Quesada, R, 2007)
"We pretreated cell lines derived from human melanomas, adenocarcinomas, and lymphomas with the PPIs omeprazole, esomeprazole, or pantoprazole and tested their response to cytotoxic drugs in cell death assays."3.72Effect of proton pump inhibitor pretreatment on resistance of solid tumors to cytotoxic drugs. ( Arancia, G; Belardelli, F; De Milito, A; Fais, S; Federici, C; Iessi, E; Logozzi, M; Lozupone, F; Luciani, F; Lugini, L; Marra, M; Molinari, A; Montinaro, A; Parmiani, G; Rivoltini, L; Spada, M, 2004)
"The case of an intramucosal adenocarcinoma diagnosed 18 months after apparently complete squamous re-epithelialisation achieved using argon plasma coagulation and high dose omeprazole (40 mg/daily) is reported in a 68 year old patient presenting initially with a Barrett's oesophagus without dysplasia."3.70Intramucosal adenocarcinoma arising under squamous re-epithelialisation of Barrett's oesophagus. ( Cremer, M; Devière, J; Peny, MO; Salmon, I; Van Laethem, JL, 2000)
" In this case report, a patient with Barrett's oesophagus complicated by high grade dysplasia and focal adenocarcinoma was treated by Nd:Yag laser then high dose rate intraluminal irradiation while on omeprazole 40 mg/day."3.69[Partial regression of Barret esophagus with high grade dysplasia and adenocarcinoma after photocoagulation and endocurietherapy under antisecretory treatment]. ( Bouché, O; Demange, L; Diébold, MD; Fremond, L; Thiefin, G; Zeitoun, P, 1995)
"pylori decreases gastric cancer risk, using preneoplastic conditions as surrogate markers."2.71Helicobacter pylori eradication and gastric preneoplastic conditions: a randomized, double-blind, placebo-controlled trial. ( Figueroa, LS; Guarner, J; Halperin, D; Herrera-Goepfert, R; Johnstone, I; Ley, C; Mohar, A; Parsonnet, J, 2004)
"pylori at 6 wk were infected at 1 yr (recurrence rates 10."2.70Eradication rate of Helicobacter pylori in a Mexican population at high risk for gastric cancer and use of serology to assess cure. ( Figueroa, LS; Guarner, J; Halperin, D; Herrera-Goepfert, R; Ley, C; Mohar, A; Parsonnet, J, 2002)
"KTP laser destruction of Barrett's esophagus induced mucosal regeneration with normal squamous cell epithelium in combination with acid suppression."2.69KTP laser destruction of dysplasia and early cancer in columnar-lined Barrett's esophagus. ( Ell, C; Gossner, L; Hahn, EG; May, A; Seitz, G; Stolte, M, 1999)
"Typical GERD symptoms are often sufficient to determine the diagnosis, but less common symptoms and signs, such as dysphagia and chronic cough, may occur."2.66Gastroesophageal Reflux Disease: A Review. ( Lagergren, J; Maret-Ouda, J; Markar, SR, 2020)
"The treatment of Barrett's esophagus is controversial."2.43[The clinical strategy for the Barrett's esophagus]. ( Goto, H; Kitabatake, S; Niwa, Y, 2005)
" Methods to optimize nocturnal acid control include careful attention to dosing schedule, using higher doses of PPIs, adding an histamine H2-receptor antagonist at bedtime to once or twice daily delayed-release PPI, or using immediate-release omeprazole (Zegerid powder for oral suspension; Santarus, Inc."2.43Review article: putting immediate-release proton-pump inhibitors into clinical practice--improving nocturnal acid control and avoiding the possible complications of excessive acid exposure. ( Katz, PO, 2005)
"The key feature of GERD is reflux of gastric contents into the esophagus."2.42Reflux disease and Barrett's esophagus. ( Haag, S; Holtmann, G, 2003)
"He was also diagnosed to have gastric cancer with Helicobacter pylori infection."2.42Extragastric mucosa-associated lymphoid tissue lymphoma showing the regression by Helicobacter pylori eradication therapy. ( Arima, N; Tsudo, M, 2003)
" Instances in which laparoscopic Nissen fundoplication should be considered include: 1) Individuals who are intolerant of proton pump inhibitor therapy because of side effects, 2) When patients are inadequately responsive to proton pump inhibitor therapy even after dosage and dose interval have been optimized, and 3) When a patient desires a permanent solution to their reflux problem that frees them of the need to chronically consume pharmaceuticals."2.41Management of GERD: medical versus surgical. ( Kahrilas, PJ, 2001)
"Short-segment Barrett's esophagus is now clearly associated with an increased risk of dysplasia or cancer compared to intestinal metaplasia of the cardia, and the cancer risk in this condition is similar to that with long-segment Barrett's esophagus."2.41Gastroesophageal reflux disease and Barrett's esophagus. ( Falk, GW, 2001)
"36), we did not find a dose-response relationship with PPI duration (P trend = 0."1.48Acid suppression medications reduce risk of oesophageal adenocarcinoma in Barrett's oesophagus: a nested case-control study in US male veterans. ( El-Serag, HB; Tan, MC; Thrift, AP; Yu, X, 2018)
"Esophageal squamous cell carcinoma developed in INK4a/Arf+/- mice (7."1.35Gastroesophageal reflux leads to esophageal cancer in a surgical model with mice. ( Chen, X; Hao, J; Liu, B; Yang, CS, 2009)
"Duodenogastric reflux is known to cause an increased frequency of cancer in the glandular portion of the stomach in rats."1.32Lanzoprazole promotes gastric carcinogenesis in rats with duodenogastric reflux. ( Maartmann-Moe, H; Viste, A; Waldum, H; Øvrebø, K, 2004)
"Strategies to prevent Barrett's-related esophageal cancer have focused on reversal of Barrett's using pharmacological or surgical antireflux therapies and endoscopically-induced injury."1.31Does chemoprevention of Barrett's esophagus using acid suppression and/or COX-2 inhibition prevent neoplastic progression? ( Fennerty, MB, 2002)
"Duodenoesophageal reflux was induced in 60 rats by performing a duodenesophagostomy."1.31Adenocarcinoma of the rat esophagus in the presence of a proton pump inhibitor: a pilot study. ( Barry, P; Burn, J; Falk, G; Moore, KH, 2001)
"Cytology from Barrett's esophagus can be misleading in the presence of severe inflammation."1.30Brush cytology in the diagnosis of neoplasia in Barrett's esophagus. ( Alderson, D; Hardwick, RH; Lott, M; Morgan, RJ; Warren, BF, 1997)
"Endoscopic ablation of Barrett's esophagus, including associated dysplasia and adenocarcinoma, can be achieved by various techniques, but few long-term results are available."1.30Laser and multipolar electrocoagulation ablation of early Barrett's adenocarcinoma: long-term follow-up. ( Bhattacharyya, A; Jaffe, PE; Sampliner, RE; Sharma, P, 1999)
"None of the rats developed esophageal cancer, but esophageal mucosal hyperplasia was more pronounced in rats receiving omeprazole."1.30Gastric acid blockade with omeprazole promotes gastric carcinogenesis induced by duodenogastric reflux. ( Adrian, TE; Hinder, RA; Perdikis, G; Profanter, C; Smyrk, T; Wetscher, GJ, 1999)
"Thirty-six patients with Barrett's esophagus and dysplasia were treated with photodynamic therapy, and sodium porfimer 2."1.29Photodynamic therapy for Barrett's esophagus: clinical update. ( Overholt, BF; Panjehpour, M, 1996)

Research

Studies (62)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.61)18.7374
1990's17 (27.42)18.2507
2000's31 (50.00)29.6817
2010's8 (12.90)24.3611
2020's5 (8.06)2.80

Authors

AuthorsStudies
Szachnowicz, S1
Duarte, AF1
Nasi, A1
da Rocha, JRM1
Seguro, FB1
Bianchi, ET1
Tustumi, F1
de Moura, EGH1
Sallum, RAA1
Cecconello, I1
Monteiro, RLR1
Kobayasi, MAMR1
Araujo, MR1
Monteiro, DR1
Andreollo, NA1
Maret-Ouda, J1
Markar, SR1
Lagergren, J1
Howden, CW1
Graham, DY1
Madka, V1
Kumar, G1
Pathuri, G1
Panneerselvam, J1
Zhang, Y1
Ganta, V1
Lightfoot, S1
Lubet, R1
Suen, CS1
Steele, VE1
Janakiram, NB1
Mohammed, A1
Rao, CV1
Tan, MC1
El-Serag, HB1
Yu, X1
Thrift, AP1
Huang, J1
Liu, H1
Sun, T1
Fang, JY1
Wang, J1
Xiong, H1
Kajiura, S1
Hosokawa, A1
Ueda, A1
Mihara, H1
Ando, T1
Fujinami, H1
Nishikawa, J1
Ogawa, K2
Minemura, M1
Sugiyama, T1
Sundaresan, S1
Kang, AJ1
Hayes, MM1
Choi, EK1
Merchant, JL1
Hao, J2
Zhang, B1
Liu, B2
Lee, M1
Hao, X1
Reuhl, KR1
Chen, X2
Yang, CS2
Sharma, P2
Triadafilopoulos, G1
Lombard, CM1
Jobe, BA1
Lord, RV1
Tomita, T1
Kim, Y1
Yamasaki, T1
Okugawa, T1
Kondo, T1
Toyoshima, F1
Sakurai, J1
Tanaka, J1
Morita, T1
Oshima, T1
Fukui, H1
Hori, K1
Watari, J1
Matsumoto, T1
Miwa, H1
Miyashita, T1
Shah, FA1
Harmon, JW1
Marti, GP1
Matsui, D1
Okamoto, K1
Makino, I1
Hayashi, H1
Oyama, K1
Nakagawara, H1
Tajima, H1
Fujita, H1
Takamura, H1
Murakami, M1
Ninomiya, I1
Kitagawa, H1
Fushida, S1
Fujimura, T1
Ohta, T1
Watson, SA1
Morris, TM1
McWilliams, DF1
Harris, J1
Evans, S1
Smith, A1
Clarke, PA1
Mohar, A2
Ley, C2
Guarner, J2
Herrera-Goepfert, R2
Figueroa, LS2
Halperin, D2
Parsonnet, J2
Barr, H2
Fennerty, MB1
Haag, S1
Holtmann, G1
Arima, N1
Tsudo, M1
Parrilla, P1
Martínez de Haro, LF1
Ortiz, A1
Munitiz, V1
Molina, J1
Bermejo, J1
Canteras, M1
Vakil, N1
Overholt, BF5
Panjehpour, M4
Halberg, DL1
Johnstone, I1
Hamaguchi, K1
Katsube, T1
Konno, S1
Aiba, M1
Viste, A1
Øvrebø, K1
Maartmann-Moe, H1
Waldum, H1
Jankowski, J1
Moayyedi, P1
Luciani, F1
Spada, M1
De Milito, A1
Molinari, A1
Rivoltini, L1
Montinaro, A1
Marra, M1
Lugini, L1
Logozzi, M1
Lozupone, F1
Federici, C1
Iessi, E1
Parmiani, G1
Arancia, G1
Belardelli, F1
Fais, S1
Tanabe, H1
Hara, H1
Ohtubo, C1
Miyokawa, N1
Sano, H1
Kitabatake, S1
Niwa, Y1
Goto, H1
Katz, PO1
Cooper, BT1
Chapman, W1
Neumann, CS1
Gearty, JC1
Wang, KK1
Burdick, JS1
Lightdale, CJ1
Kimmey, M1
Nava, HR1
Sivak, MV1
Nishioka, N1
Marcon, N1
Pedrosa, M1
Bronner, MP1
Grace, M1
Depot, M1
Fernández, FA1
Pintor, E1
Quesada, R1
Garcés, FJ1
Lönnroth, C1
Andersson, M1
Arvidsson, A1
Nordgren, S1
Brevinge, H1
Lagerstedt, K1
Lundholm, K1
Fremond, L1
Bouché, O1
Diébold, MD1
Demange, L1
Zeitoun, P1
Thiefin, G1
Waldum, HL1
Brenna, E1
Hassall, E1
Ertan, A1
Zimmerman, M1
Younes, M1
Matsunaga, K1
Oofukuji, M1
Syukuwa, S1
Osabe, M1
Takeno, Y1
Isomoto, H1
Mizuta, Y1
Kohno, S1
Hardwick, RH1
Morgan, RJ1
Warren, BF1
Lott, M1
Alderson, D1
Wayman, J1
Hayes, N1
Griffin, SM1
Chen, D1
Destrée, M1
Håkanson, R1
Willems, G1
Gossner, L1
May, A1
Stolte, M1
Seitz, G1
Hahn, EG1
Ell, C1
Haydek, JM1
Pace, F1
Bianchi Porro, G1
Jaffe, PE1
Bhattacharyya, A1
Sampliner, RE1
Wetscher, GJ1
Hinder, RA1
Smyrk, T1
Perdikis, G1
Adrian, TE1
Profanter, C1
Van Laethem, JL1
Peny, MO1
Salmon, I1
Cremer, M1
Devière, J1
Adamsson, I1
Edlund, C1
Nord, CE1
Sauer, J1
Junginger, T1
Kahrilas, PJ1
Falk, GW1
Moore, KH1
Barry, P1
Burn, J1
Falk, G1
Keto, Y1
Ebata, M1
Okabe, S1
Graffner, H1
Singh, G1
Chaudry, I1
Milsom, JW1
Bonfils, SJ1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluating Efficacy and Safety of Combined Thread Embedding and Auricular Acupuncture in Gastroesophageal Reflux Disease With Liver Qi Invading Stomach Pattern: A Randomized Controlled Trial[NCT06157424]66 participants (Anticipated)Interventional2023-12-06Recruiting
Evaluation of MicroRNA Expression in Blood and Cytology Specimens as a Novel Method for Detecting Barrett's Esophagus[NCT02464930]220 participants (Anticipated)Observational2015-04-30Recruiting
Endoscopic Resection or Ablation for Patients With Dysplasia or Intramucosal Cancer in Barrett's Esophagus[NCT01572987]12 participants (Actual)Interventional2011-09-30Terminated (stopped due to Recruitment goals not being met)
Evaluation of Performance Characteristics of Capsule Endoscopy With PillCam UGI Capsule Compared to Standard Endoscopy for Screening of Barrett's Esophagus: A Prospective Tandem Study[NCT03167970]21 participants (Actual)Observational2017-05-03Completed
A Phase II, Multi-Center Study of Interventional Spray Cryotherapy for Early-Stage Esophageal Cancer (ICE-CANCER)[NCT01868139]1 participants (Actual)Interventional2013-06-30Terminated (stopped due to insufficient accrual)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

17 reviews available for omeprazole and Adenocarcinoma

ArticleYear
Gastroesophageal Reflux Disease: A Review.
    JAMA, 2020, 12-22, Volume: 324, Issue:24

    Topics: Adenocarcinoma; Barrett Esophagus; Diagnosis, Differential; Esophageal Neoplasms; Fundoplication; Ga

2020
Clinical practice. Barrett's esophagus.
    The New England journal of medicine, 2009, Dec-24, Volume: 361, Issue:26

    Topics: Adenocarcinoma; Algorithms; Barrett Esophagus; Esophageal Neoplasms; Esophagectomy; Esophagoscopy; E

2009
Clinical practice. Barrett's esophagus.
    The New England journal of medicine, 2009, Dec-24, Volume: 361, Issue:26

    Topics: Adenocarcinoma; Algorithms; Barrett Esophagus; Esophageal Neoplasms; Esophagectomy; Esophagoscopy; E

2009
Clinical practice. Barrett's esophagus.
    The New England journal of medicine, 2009, Dec-24, Volume: 361, Issue:26

    Topics: Adenocarcinoma; Algorithms; Barrett Esophagus; Esophageal Neoplasms; Esophagectomy; Esophagoscopy; E

2009
Clinical practice. Barrett's esophagus.
    The New England journal of medicine, 2009, Dec-24, Volume: 361, Issue:26

    Topics: Adenocarcinoma; Algorithms; Barrett Esophagus; Esophageal Neoplasms; Esophagectomy; Esophagoscopy; E

2009
Clinical practice. Barrett's esophagus.
    The New England journal of medicine, 2009, Dec-24, Volume: 361, Issue:26

    Topics: Adenocarcinoma; Algorithms; Barrett Esophagus; Esophageal Neoplasms; Esophagectomy; Esophagoscopy; E

2009
Clinical practice. Barrett's esophagus.
    The New England journal of medicine, 2009, Dec-24, Volume: 361, Issue:26

    Topics: Adenocarcinoma; Algorithms; Barrett Esophagus; Esophageal Neoplasms; Esophagectomy; Esophagoscopy; E

2009
Clinical practice. Barrett's esophagus.
    The New England journal of medicine, 2009, Dec-24, Volume: 361, Issue:26

    Topics: Adenocarcinoma; Algorithms; Barrett Esophagus; Esophageal Neoplasms; Esophagectomy; Esophagoscopy; E

2009
Clinical practice. Barrett's esophagus.
    The New England journal of medicine, 2009, Dec-24, Volume: 361, Issue:26

    Topics: Adenocarcinoma; Algorithms; Barrett Esophagus; Esophageal Neoplasms; Esophagectomy; Esophagoscopy; E

2009
Clinical practice. Barrett's esophagus.
    The New England journal of medicine, 2009, Dec-24, Volume: 361, Issue:26

    Topics: Adenocarcinoma; Algorithms; Barrett Esophagus; Esophageal Neoplasms; Esophagectomy; Esophagoscopy; E

2009
Does antireflux surgery prevent progression of Barrett's esophagus?
    Minerva chirurgica, 2011, Volume: 66, Issue:1

    Topics: Adenocarcinoma; Barrett Esophagus; Cohort Studies; Combined Modality Therapy; Disease Progression; E

2011
Do proton pump inhibitors protect against cancer progression in GERD?
    Surgery today, 2013, Volume: 43, Issue:8

    Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Barrett Esop

2013
Reflux disease and Barrett's esophagus.
    Endoscopy, 2003, Volume: 35, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenocarcinoma; Anti-Ulcer Agents; Barrett Esophagus; Endos

2003
Extragastric mucosa-associated lymphoid tissue lymphoma showing the regression by Helicobacter pylori eradication therapy.
    British journal of haematology, 2003, Volume: 120, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenocarcinoma; Aged; Amoxicillin; Clarithromycin; Drug The

2003
Review article: test and treat or treat and test in reflux disease?
    Alimentary pharmacology & therapeutics, 2003, Volume: 17 Suppl 2

    Topics: Adenocarcinoma; Ambulatory Care; Anti-Ulcer Agents; Barrett Esophagus; Esophageal Neoplasms; Gastroe

2003
[The clinical strategy for the Barrett's esophagus].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Ba

2005
Review article: putting immediate-release proton-pump inhibitors into clinical practice--improving nocturnal acid control and avoiding the possible complications of excessive acid exposure.
    Alimentary pharmacology & therapeutics, 2005, Volume: 22 Suppl 3

    Topics: Adenocarcinoma; Barrett Esophagus; Chronotherapy; Delayed-Action Preparations; Disease Progression;

2005
Barrett's esophagus: new definitions and approaches in children.
    Journal of pediatric gastroenterology and nutrition, 1993, Volume: 16, Issue:4

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Barrett Esophagus; Child; Child, Preschool; Cimetidine; End

1993
Gastro-oesophageal reflux and Helicobacter pylori.
    Italian journal of gastroenterology and hepatology, 1998, Volume: 30 Suppl 3

    Topics: Adenocarcinoma; Anti-Ulcer Agents; Barrett Esophagus; Diagnosis, Differential; Esophageal Neoplasms;

1998
Microbial ecology and treatment of Helicobacter pylori infections: review.
    Journal of chemotherapy (Florence, Italy), 2000, Volume: 12, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin;

2000
[Conservative and surgical antireflux therapy as prevention of carcinoma].
    Zentralblatt fur Chirurgie, 2000, Volume: 125, Issue:5

    Topics: Adenocarcinoma; Anti-Ulcer Agents; Barrett Esophagus; Biopsy; Clinical Trials as Topic; Esophageal N

2000
Management of GERD: medical versus surgical.
    Seminars in gastrointestinal disease, 2001, Volume: 12, Issue:1

    Topics: Adenocarcinoma; Anti-Ulcer Agents; Costs and Cost Analysis; Esophageal Neoplasms; Esophagitis, Pepti

2001
Gastroesophageal reflux disease and Barrett's esophagus.
    Endoscopy, 2001, Volume: 33, Issue:2

    Topics: Adenocarcinoma; Barrett Esophagus; Endoscopy, Gastrointestinal; Esophageal Neoplasms; Esophagus; Gas

2001
[Pharmacological study on the pathological changes of the gastric mucosa in Helicobacter pylori-infected Mongolian gerbils].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2001, Volume: 118, Issue:4

    Topics: Adenocarcinoma; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer

2001
[From acid secretion inhibition to enterochromaffin-like cell proliferation. Traps on the path].
    Gastroenterologie clinique et biologique, 1991, Volume: 15, Issue:5 ( Pt 2)

    Topics: Adenocarcinoma; Carcinoid Tumor; Enterochromaffin Cells; Gastric Mucosa; Gastrins; Gastritis, Atroph

1991

Trials

7 trials available for omeprazole and Adenocarcinoma

ArticleYear
Prospective randomized controlled trial to compare the effects of omeprazole and famotidine in preventing delayed bleeding and promoting ulcer healing after endoscopic submucosal dissection.
    Journal of gastroenterology and hepatology, 2012, Volume: 27, Issue:9

    Topics: Adenocarcinoma; Adenoma; Aged; Aged, 80 and over; Analysis of Variance; Famotidine; Female; Gastric

2012
Eradication rate of Helicobacter pylori in a Mexican population at high risk for gastric cancer and use of serology to assess cure.
    The American journal of gastroenterology, 2002, Volume: 97, Issue:10

    Topics: Adenocarcinoma; Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Antibodies, Bacterial;

2002
Long-term results of a randomized prospective study comparing medical and surgical treatment of Barrett's esophagus.
    Annals of surgery, 2003, Volume: 237, Issue:3

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Anti-Ulcer Agents; Barrett Esophagus; Child; Esophageal Neo

2003
Helicobacter pylori eradication and gastric preneoplastic conditions: a randomized, double-blind, placebo-controlled trial.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2004, Volume: 13, Issue:1

    Topics: Adenocarcinoma; Adult; Anti-Ulcer Agents; Double-Blind Method; Female; Gastritis; Helicobacter Infec

2004
Five-year efficacy and safety of photodynamic therapy with Photofrin in Barrett's high-grade dysplasia.
    Gastrointestinal endoscopy, 2007, Volume: 66, Issue:3

    Topics: Adenocarcinoma; Aged; Anti-Ulcer Agents; Barrett Esophagus; Biopsy; Combined Modality Therapy; Dihem

2007
Preoperative treatment with a non-steroidal anti-inflammatory drug (NSAID) increases tumor tissue infiltration of seemingly activated immune cells in colorectal cancer.
    Cancer immunity, 2008, Feb-29, Volume: 8

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cell Mo

2008
KTP laser destruction of dysplasia and early cancer in columnar-lined Barrett's esophagus.
    Gastrointestinal endoscopy, 1999, Volume: 49, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Barrett Esophagus; Esophageal Neo

1999

Other Studies

38 other studies available for omeprazole and Adenocarcinoma

ArticleYear
Laparoscopic total fundoplication is superior to medical treatment for reducing the cancer risk in Barrett's esophagus: a long-term analysis.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2022, Nov-15, Volume: 35, Issue:11

    Topics: Adenocarcinoma; Barrett Esophagus; Esophageal Neoplasms; Fundoplication; Humans; Laparoscopy; Omepra

2022
Omeprazole and adenocarcinoma in the stomach of rats submitted to duodenogastric reflux. Is there a protective effect?
    Acta cirurgica brasileira, 2020, Volume: 35, Issue:9

    Topics: Adenocarcinoma; Animals; Duodenogastric Reflux; Gastric Mucosa; Humans; Omeprazole; Proton Pump Inhi

2020
Recent Developments Pertaining to H. pylori Infection.
    The American journal of gastroenterology, 2021, 01-01, Volume: 116, Issue:1

    Topics: Adenocarcinoma; Amoxicillin; Antacids; Anti-Bacterial Agents; Bismuth; Clarithromycin; Drug Resistan

2021
Proton Pump Inhibitor Omeprazole Suppresses Carcinogen-induced Colonic Adenoma Progression to Adenocarcinoma in F344 Rat.
    Cancer prevention research (Philadelphia, Pa.), 2021, Volume: 14, Issue:11

    Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Omeprazole; Proton P

2021
Acid suppression medications reduce risk of oesophageal adenocarcinoma in Barrett's oesophagus: a nested case-control study in US male veterans.
    Alimentary pharmacology & therapeutics, 2018, Volume: 48, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Barrett Esophagus; Case-Contro

2018
Omeprazole prevents CDX2 and SOX9 expression by inhibiting hedgehog signaling in Barrett's esophagus cells.
    Clinical science (London, England : 1979), 2019, 02-14, Volume: 133, Issue:3

    Topics: Adenocarcinoma; Antineoplastic Agents; Barrett Esophagus; CDX2 Transcription Factor; Cell Line, Tumo

2019
Effective healing of endoscopic submucosal dissection-induced ulcers by a single week of proton pump inhibitor treatment: a retrospective study.
    BMC research notes, 2015, Apr-15, Volume: 8

    Topics: Adenocarcinoma; Adenoma; Aged; Anti-Ulcer Agents; Female; Gastric Mucosa; Gastroscopy; Humans; Male;

2015
Deletion of
    Gut, 2017, Volume: 66, Issue:6

    Topics: Adenocarcinoma; Adult; Animals; Benzodiazepines; Carcinogenesis; Carcinoid Tumor; Cell Line, Tumor;

2017
Effect of alpha-tocopherol, N-acetylcysteine and omeprazole on esophageal adenocarcinoma formation in a rat surgical model.
    International journal of cancer, 2009, Mar-15, Volume: 124, Issue:6

    Topics: Acetylcysteine; Adenocarcinoma; alpha-Tocopherol; Animals; Disease Models, Animal; Esophageal Neopla

2009
Gastroesophageal reflux leads to esophageal cancer in a surgical model with mice.
    BMC gastroenterology, 2009, Jul-23, Volume: 9

    Topics: Adenocarcinoma; Animals; Anti-Ulcer Agents; Carcinoma, Squamous Cell; Cyclin-Dependent Kinase Inhibi

2009
"War and Peace" with Barrett's esophagus.
    Digestive diseases and sciences, 2011, Volume: 56, Issue:4

    Topics: Adenocarcinoma; Aged; Anti-Ulcer Agents; Antihypertensive Agents; Aspirin; Barrett Esophagus; Celeco

2011
Potential role of endocrine gastrin in the colonic adenoma carcinoma sequence.
    British journal of cancer, 2002, Aug-27, Volume: 87, Issue:5

    Topics: Adenocarcinoma; Adenoma; Animals; Colonic Neoplasms; Computer Systems; Enzyme Inhibitors; Female; Fi

2002
Ablative mucosectomy is the procedure of choice to prevent Barrett's cancer.
    Gut, 2003, Volume: 52, Issue:1

    Topics: Adenocarcinoma; Anti-Ulcer Agents; Barrett Esophagus; Catheter Ablation; Esophageal Neoplasms; Esoph

2003
Does chemoprevention of Barrett's esophagus using acid suppression and/or COX-2 inhibition prevent neoplastic progression?
    Reviews in gastroenterological disorders, 2002, Volume: 2 Suppl 2

    Topics: Adenocarcinoma; Anti-Ulcer Agents; Barrett Esophagus; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors;

2002
Photodynamic therapy for Barrett's esophagus with dysplasia and/or early stage carcinoma: long-term results.
    Gastrointestinal endoscopy, 2003, Volume: 58, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Barrett Esophagus; Esophageal Neo

2003
Does eradication of Helicobacter pylori reduce the risk of carcinogenesis in the residual stomach after gastrectomy for early gastric cancer? Comparison of mucosal lesions in the residual stomach before and after Helicobacter pylori eradication.
    Langenbeck's archives of surgery, 2004, Volume: 389, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenocarcinoma; Aged; Amoxicillin; Anti-Bacterial Agents; A

2004
Lanzoprazole promotes gastric carcinogenesis in rats with duodenogastric reflux.
    Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2004, Volume: 7, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenocarcinoma; Administration, Oral; Animals; Duodenogastr

2004
Re: Cost-effectiveness of aspirin chemoprevention for Barrett's esophagus.
    Journal of the National Cancer Institute, 2004, Jun-02, Volume: 96, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Anti-Ulcer Agents; Aspirin; Barrett Esophagus; Cost-Benefit Analysis; D

2004
Effect of proton pump inhibitor pretreatment on resistance of solid tumors to cytotoxic drugs.
    Journal of the National Cancer Institute, 2004, Nov-17, Volume: 96, Issue:22

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenocarcinoma; Animals; Antineoplastic Agents; Benzimidazo

2004
[Disappearance of gastric adenocarcinoma in hyperplastic polyp after eradication of Heliobacter pylori. Report of a case].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2005, Volume: 102, Issue:5

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Anti-Bacterial Agents; Clarithromycin; Drug Therapy, Combin

2005
Continuous treatment of Barrett's oesophagus patients with proton pump inhibitors up to 13 years: observations on regression and cancer incidence.
    Alimentary pharmacology & therapeutics, 2006, Mar-15, Volume: 23, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenocarcinoma; Adult; Aged; Aged, 80 and over; Barrett Eso

2006
[Toxic epidermal necrolysis induced by phenytoin and whole brain radiotherapy].
    Actas dermo-sifiliograficas, 2007, Volume: 98, Issue:7

    Topics: Adenocarcinoma; Aged; Anticonvulsants; Brain Neoplasms; Breast Neoplasms; Combined Modality Therapy;

2007
Barrett's esophagus: photodynamic therapy for ablation of dysplasia, reduction of specialized mucosa, and treatment of superficial esophageal cancer.
    Gastrointestinal endoscopy, 1995, Volume: 42, Issue:1

    Topics: Adenocarcinoma; Aged; Anti-Ulcer Agents; Antineoplastic Agents; Barrett Esophagus; Biopsy; Esophagea

1995
[Partial regression of Barret esophagus with high grade dysplasia and adenocarcinoma after photocoagulation and endocurietherapy under antisecretory treatment].
    Gastroenterologie clinique et biologique, 1995, Volume: 19, Issue:1

    Topics: Adenocarcinoma; Barrett Esophagus; Brachytherapy; Combined Modality Therapy; Endoscopy, Digestive Sy

1995
Omeprazole tolerability.
    Drug safety, 1994, Volume: 11, Issue:6

    Topics: Adenocarcinoma; Animals; Humans; Neuroendocrine Tumors; Omeprazole; Rats; Stomach Neoplasms

1994
Esophageal adenocarcinoma associated with Barrett's esophagus: long-term management with laser ablation.
    The American journal of gastroenterology, 1995, Volume: 90, Issue:12

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Barrett Esophagus; Endoscopy; Esophageal Neoplasms; Esophag

1995
Photodynamic therapy for Barrett's esophagus: clinical update.
    The American journal of gastroenterology, 1996, Volume: 91, Issue:9

    Topics: Adenocarcinoma; Adenoma, Villous; Anti-Ulcer Agents; Barrett Esophagus; Biopsy; Esophageal Neoplasms

1996
[Successful eradication of H. pylori in an elderly patient with gastric cancer after effective UFT-E therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:15

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abietanes; Adenocarcinoma; Aged; Aged, 80 and over; Anti-Ba

1997
Brush cytology in the diagnosis of neoplasia in Barrett's esophagus.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 1997, Volume: 10, Issue:4

    Topics: Adenocarcinoma; Anti-Ulcer Agents; Barrett Esophagus; Biopsy; Cell Count; Cell Nucleus; Chromatin; C

1997
The response of early gastric cancer to proton-pump inhibitors.
    The New England journal of medicine, 1998, Jun-25, Volume: 338, Issue:26

    Topics: Adenocarcinoma; Adult; Aged; Diagnostic Errors; Female; Humans; Omeprazole; Proton Pump Inhibitors;

1998
Endogenous hypergastrinaemia does not promote growth of colonic mucosa or of a transplanted colon adenocarcinoma in rats.
    European journal of gastroenterology & hepatology, 1998, Volume: 10, Issue:4

    Topics: Adenocarcinoma; Animals; Cell Division; Colon; Colonic Neoplasms; Enzyme Inhibitors; Gastrins; Intes

1998
Photodynamic therapy for Barrett's esophagus: follow-up in 100 patients.
    Gastrointestinal endoscopy, 1999, Volume: 49, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Antineoplastic Agents; Barrett Es

1999
Laser and multipolar electrocoagulation ablation of early Barrett's adenocarcinoma: long-term follow-up.
    Gastrointestinal endoscopy, 1999, Volume: 49, Issue:4 Pt 1

    Topics: Adenocarcinoma; Aged; Anti-Ulcer Agents; Barrett Esophagus; Electrocoagulation; Esophageal Neoplasms

1999
Gastric acid blockade with omeprazole promotes gastric carcinogenesis induced by duodenogastric reflux.
    Digestive diseases and sciences, 1999, Volume: 44, Issue:6

    Topics: Adenocarcinoma; Animals; Anti-Ulcer Agents; Disease Models, Animal; Duodenogastric Reflux; Esophagea

1999
Intramucosal adenocarcinoma arising under squamous re-epithelialisation of Barrett's oesophagus.
    Gut, 2000, Volume: 46, Issue:4

    Topics: Adenocarcinoma; Aged; Anti-Ulcer Agents; Barrett Esophagus; Esophageal Neoplasms; Esophagus; Humans;

2000
Adenocarcinoma of the rat esophagus in the presence of a proton pump inhibitor: a pilot study.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2001, Volume: 14, Issue:1

    Topics: Adenocarcinoma; Animals; Disease Models, Animal; Esophageal Neoplasms; Esophagostomy; Gastroesophage

2001
Omeprazole-induced hypergastrinemia does not influence growth of colon carcinoma.
    Digestive diseases and sciences, 1992, Volume: 37, Issue:4

    Topics: Adenocarcinoma; Animals; Cell Division; Colonic Neoplasms; Gastrins; Liver Neoplasms; Mice; Mice, In

1992
Omeprazole.
    Lancet (London, England), 1987, Dec-19, Volume: 2, Issue:8573

    Topics: Adenocarcinoma; Adult; Aged; Animals; Esophagitis, Peptic; Humans; Omeprazole; Rats; Stomach Neoplas

1987