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omega-n-methylarginine and Hypotension

omega-n-methylarginine has been researched along with Hypotension in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's24 (75.00)18.2507
2000's6 (18.75)29.6817
2010's2 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hobbs, AJ; Sand, CA1
Barbara, JA; Hewitson, CL; Mangoni, AA; McAteer-Carr, B; Whiting, MJ; Woodman, RJ1
Kondapaneni, M; Laubach, VE; McGregor, JR; Salvemini, D; Samlowski, WE; Tharkar, S1
Chelly, B; Chelly, JE; Doursout, MF; Fischer, UM; Hartley, CJ; Liang, Y; Oguchi, T1
Kondapaneni, M; Laubach, VE; McGregor, JR; Salvemini, D; Samlowski, WE1
Boeynaems, JM; Buurman, W; Preiser, JC; Vincent, JL; Wachel, D; Zhang, H1
Blantz, RC1
Agarwal, N; Chalasani, S; Lentz, KE; Lomis, TJ; Lowenstein, CJ; McMillan, A; Rhoads, JE; Siffring, CW; Stauffer, KE; Ziegler, DW1
Chang, CH; Chang, JP; Lin, PJ1
Gidday, JM; Zhu, Y1
Bättig, U; Cakmakci, M; Geroulanos, S; Schilling, J1
Ewer, M; Fonseca, GA; Griffith, OW; Jones, E; Kilbourn, RG; Logothetis, CJ; Price, K; Striegel, A1
Alak, AM; Cromeens, DM; Flaherty, MJ; Griffith, OW; Gross, SS; Kilbourn, RG; Owen-Schaub, LB; Santee, SM1
Klabunde, RE; Ritger, RC; Slayton, KJ1
Fukuuchi, Y; Gomi, S; Mihara, B; Nagata, E; Nogawa, S; Nozaki, H; Shirai, T; Tanaka, K1
Bennett, T; Gardiner, SM; Kemp, PA; March, JE1
Hisamochi, K; Raikar, BL; Raikar, GV; Schaff, HV1
Griffith, OW; Kilbourn, RG1
Chaudhry, GM; Esakof, DD; Hariawala, M; Horowitz, JR; Isner, JM; Rivard, A; Sheriff, DD; Symes, JF; van der Zee, R1
Baylis, SA; Charles, IG; Heaton, ND; Martin, JF; McPeake, JR; Moncada, S; Robinson, NM; Smith, RE; Williams, R1
Banks, SM; Cobb, JP; Cunnion, RE; Danner, RL; Eichacker, PQ; Freeman, BD; Karzai, W; Natanson, C; Quezado, MJ; Quezado, ZM; Sevransky, JE; Yan, L1
Ballejo, G; Resende, AC; Salgado, MC1
Ekin, S; Evora, PR; Pearson, PJ; Schaff, HV1
Fonseca, GA; Griffith, OW; Kilbourn, RG; Trissel, LA1
Halliwill, JR; Joyner, MJ; Minson, CT1
Hirooka, Y; Kishi, T; Sakai, K; Shigematsu, H; Shimokawa, H; Takeshita, A1
Elmore, SP; Oliver, JD; Simpson, LM; Watts, JA1
Helgren, MC; Klabunde, RE1
Newman, CM; O'Shaughnessy, KM; Warren, JB1
Calignano, A; Mancuso, F; Persico, P; Sorrentino, L1
Ayrancioglu, K; Evora, PR; Pearson, PJ; Schaff, HV1
Adams, J; Griffith, OW; Gross, SS; Jubran, A; Kilbourn, RG; Levi, R; Lodato, RF1

Reviews

4 review(s) available for omega-n-methylarginine and Hypotension

ArticleYear
The nuances of NO synthase regulation in sepsis: Could targeting BH4 be the answer?
    Vascular pharmacology, 2016, Volume: 77

    Topics: Animals; Biopterins; Endothelium, Vascular; Enzyme Inhibitors; Humans; Hypotension; Nitric Oxide Synthase; omega-N-Methylarginine; Sepsis

2016
Vascular biology: relevance of nitric oxide in vascular and nonvascular tissue with normal and decreased renal function.
    Blood purification, 1994, Volume: 12, Issue:1

    Topics: Amino Acid Oxidoreductases; Arginine; Endothelium, Vascular; Enzyme Induction; Hemodynamics; Humans; Hypotension; Inflammation; Kidney Diseases; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Shock, Septic

1994
Design of nitric oxide synthase inhibitors and their use to reverse hypotension associated with cancer immunotherapy.
    Advances in enzyme regulation, 1997, Volume: 37

    Topics: Animals; Arginine; Blood Pressure; Dogs; Drug Design; Enzyme Inhibitors; Humans; Hypotension; Immunotherapy; Interleukin-2; Neoplasms; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine

1997
Role of non-nitric oxide non-prostaglandin endothelium-derived relaxing factor(s) in bradykinin vasodilation.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1998, Volume: 31, Issue:9

    Topics: Animals; Bradykinin; Cannabinoid Receptor Modulators; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Hypotension; Nitric Acid; Nitric Oxide; omega-N-Methylarginine; Potassium Channels; Prostaglandins; Vasodilation; Vasomotor System

1998

Trials

3 trial(s) available for omega-n-methylarginine and Hypotension

ArticleYear
NG-methyl-L-arginine, an inhibitor of nitric oxide synthase, reverses interleukin-2-induced hypotension.
    Critical care medicine, 1995, Volume: 23, Issue:6

    Topics: Adult; Arginine; Carcinoma, Renal Cell; Drug Administration Schedule; Female; Hemodynamics; Humans; Hypotension; Interleukin-2; Male; Middle Aged; Nitric Oxide; omega-N-Methylarginine; Pilot Projects; Prospective Studies

1995
Strategies to reduce side effects of interleukin-2: evaluation of the antihypotensive agent NG-monomethyl-L-arginine.
    The cancer journal from Scientific American, 2000, Volume: 6 Suppl 1

    Topics: Adult; Carcinoma, Renal Cell; Dose-Response Relationship, Drug; Female; Hemodynamics; Humans; Hypotension; Interleukin-2; Kidney Neoplasms; Killer Cells, Lymphokine-Activated; Male; Middle Aged; Nitrates; omega-N-Methylarginine

2000
Effect of systemic nitric oxide synthase inhibition on postexercise hypotension in humans.
    Journal of applied physiology (Bethesda, Md. : 1985), 2000, Volume: 89, Issue:5

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Cardiac Output; Cold Temperature; Enzyme Inhibitors; Female; Heart Rate; Humans; Hypotension; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phentolamine; Physical Exertion; Sympathetic Nervous System; Vascular Resistance

2000

Other Studies

25 other study(ies) available for omega-n-methylarginine and Hypotension

ArticleYear
Symmetric dimethylarginine is an independent predictor of intradialytic hypotension.
    American journal of hypertension, 2008, Volume: 21, Issue:8

    Topics: Aged; Arginine; Biomarkers; Blood Pressure; Female; Humans; Hypotension; Kidney Failure, Chronic; Male; Middle Aged; omega-N-Methylarginine; Predictive Value of Tests; Renal Dialysis

2008
Endothelial nitric oxide synthase is a key mediator of interleukin-2-induced hypotension and vascular leak syndrome.
    Journal of immunotherapy (Hagerstown, Md. : 1997), 2011, Volume: 34, Issue:5

    Topics: Animals; Blood Pressure; Capillary Leak Syndrome; Carcinoma, Renal Cell; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Humans; Hypotension; Interleukin-2; Manganese; Melanoma; Methylene Blue; Mice; Mice, Inbred Strains; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Organometallic Compounds; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Soluble Guanylyl Cyclase; Superoxides

2011
Distribution of NOS isoforms in a porcine endotoxin shock model.
    Shock (Augusta, Ga.), 2008, Volume: 29, Issue:6

    Topics: Animals; Cardiomyopathies; Coronary Circulation; Disease Models, Animal; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Guanidines; Hemodynamics; Hypotension; Isoenzymes; Lipopolysaccharides; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Organ Specificity; Shock, Septic; Swine; Vasoconstriction; Vasodilation; Vasodilator Agents

2008
Inducible nitric oxide synthase (iNOS) is not required for IL-2-induced hypotension and vascular leak syndrome in mice.
    Journal of immunotherapy (Hagerstown, Md. : 1997), 2008, Volume: 31, Issue:4

    Topics: Animals; Capillary Leak Syndrome; Capillary Permeability; Genetic Predisposition to Disease; Hypotension; Interferon-gamma; Interleukin-2; Lysine; Manganese; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Organometallic Compounds

2008
Is endotoxin-induced hypotension related to nitric oxide formation?
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1994, Volume: 26, Issue:1

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Dogs; Endotoxins; Hemodynamics; Hypotension; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Oxygen; Random Allocation; Shock, Septic; Tumor Necrosis Factor-alpha

1994
First place winner of the Conrad Jobst Award in the gold medal paper competition. Nitric oxide synthase inhibitors N-monomethylarginine and aminoguanidine prevent the progressive and severe hypotension associated with a rat model of pancreatitis.
    The American surgeon, 1995, Volume: 61, Issue:1

    Topics: Amylases; Animals; Arginine; Blood Pressure; Calcium; Clinical Protocols; Disease Models, Animal; Drug Evaluation, Preclinical; Fluid Therapy; Guanidines; Humans; Hypotension; Immunohistochemistry; Male; Multiple Organ Failure; Nitric Oxide; omega-N-Methylarginine; Pancreatitis; Premedication; Rats; Rats, Sprague-Dawley; Resuscitation; Severity of Illness Index

1995
Reversal of refractory hypotension in septic shock by inhibitor of nitric oxide synthase.
    Chest, 1994, Volume: 106, Issue:2

    Topics: Amino Acid Oxidoreductases; Arginine; Cardiac Output, High; Fatal Outcome; Humans; Hypotension; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Shock, Septic

1994
Nitric oxide does not mediate autoregulation of retinal blood flow in newborn pig.
    The American journal of physiology, 1995, Volume: 269, Issue:3 Pt 2

    Topics: Animals; Animals, Newborn; Arginine; Arterioles; Female; Homeostasis; Hypercapnia; Hypotension; Hypoxia; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Retinal Vessels; Swine; Vasodilation; Vasomotor System

1995
A new approach in the treatment of hypotension in human septic shock by NG-monomethyl-L-arginine, an inhibitor of the nitric oxide synthetase.
    Intensive care medicine, 1993, Volume: 19, Issue:4

    Topics: Adult; Amino Acid Oxidoreductases; Arginine; Blood Pressure; Cardiac Output; Combined Modality Therapy; Critical Care; Dose-Response Relationship, Drug; Humans; Hypotension; Male; Necrosis; Nitric Oxide Synthase; omega-N-Methylarginine; Pancreatitis; Pseudomonas aeruginosa; Pseudomonas Infections; Recurrence; Shock, Septic; Staphylococcal Infections

1993
NG-methyl-L-arginine, an inhibitor of nitric oxide formation, reverses IL-2-mediated hypotension in dogs.
    Journal of applied physiology (Bethesda, Md. : 1985), 1994, Volume: 76, Issue:3

    Topics: Animals; Antineoplastic Agents; Arginine; Blood Pressure; Blood Urea Nitrogen; Cell Division; Creatinine; Dogs; Enzymes; Glioma; Hypotension; Interleukin-2; Killer Cells, Lymphokine-Activated; Leukocyte Count; Lymphocytes; Male; Monocytes; Nitric Oxide; omega-N-Methylarginine; Thrombocytopenia; Tumor Cells, Cultured

1994
NG-methyl-L-arginine restores arterial pressure in hemorrhaged rats.
    Circulatory shock, 1993, Volume: 40, Issue:1

    Topics: Animals; Arginine; Arteries; Blood Pressure; Disease Models, Animal; Hypotension; Male; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; Vascular Resistance

1993
Inhibition of nitric oxide synthesis impairs autoregulation of local cerebral blood flow in the rat.
    Neuroreport, 1993, Volume: 4, Issue:3

    Topics: Animals; Arginine; Autoradiography; Blood Gas Analysis; Blood Pressure; Brain; Brain Chemistry; Cerebral Hemorrhage; Cerebrovascular Circulation; Hypotension; Injections, Intravenous; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Wistar; Vascular Resistance

1993
Cardiac and regional haemodynamics, inducible nitric oxide synthase (NOS) activity, and the effects of NOS inhibitors in conscious, endotoxaemic rats.
    British journal of pharmacology, 1995, Volume: 116, Issue:3

    Topics: Animals; Arginine; Cardiac Output; Disease Models, Animal; Enzyme Induction; Hemodynamics; Hypotension; Lipopolysaccharides; Lung; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Reproducibility of Results; Stroke Volume; Tachycardia

1995
Nitric oxide inhibition attenuates systemic hypotension produced by protamine.
    The Journal of thoracic and cardiovascular surgery, 1996, Volume: 111, Issue:6

    Topics: Animals; Arginine; Blood Pressure; Cardiac Output; Cyclic GMP; Dogs; Endothelium, Vascular; Enzyme Inhibitors; Female; Hemodynamics; Heparin; Hypotension; In Vitro Techniques; Male; Methylene Blue; Models, Cardiovascular; Myocardial Contraction; Nitric Oxide; omega-N-Methylarginine; Protamines; Rabbits

1996
Vascular endothelial growth factor/vascular permeability factor produces nitric oxide-dependent hypotension. Evidence for a maintenance role in quiescent adult endothelium.
    Arteriosclerosis, thrombosis, and vascular biology, 1997, Volume: 17, Issue:11

    Topics: Animals; Aorta; Cholesterol, Dietary; Diet, Atherogenic; Echocardiography; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Inhibitors; Hemodynamics; Humans; Hypercholesterolemia; Hypotension; Lymphokines; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rabbits; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; Recombinant Proteins; Secretory Rate; Swine; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Vasodilation

1997
Induction and role of NO synthase in hypotensive hepatic failure.
    Arteriosclerosis, thrombosis, and vascular biology, 1997, Volume: 17, Issue:11

    Topics: Acetylcholine; Adult; Drug Resistance; Endothelium, Vascular; Enzyme Induction; Enzyme Inhibitors; Hepatic Artery; Humans; Hypotension; Liver Failure; Liver Transplantation; Middle Aged; Nitric Oxide Synthase; omega-N-Methylarginine; Phenylephrine; RNA, Messenger; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents; Vasodilation

1997
Effects of L-NMMA and fluid loading on TNF-induced cardiovascular dysfunction in dogs.
    American journal of respiratory and critical care medicine, 1998, Volume: 157, Issue:5 Pt 1

    Topics: Animals; Dogs; Enzyme Inhibitors; Hemodynamics; Hypotension; Infusions, Intravenous; Isotonic Solutions; omega-N-Methylarginine; Pulmonary Wedge Pressure; Ringer's Solution; Tumor Necrosis Factor-alpha; Venous Pressure; Ventricular Dysfunction, Left; Water-Electrolyte Balance

1998
Endothelium-dependent vasodilation in response to Pseudomonas aeruginosa lipopolysaccharide: an in vitro study on canine arteries.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1998, Volume: 31, Issue:10

    Topics: Animals; Coronary Vessels; Dogs; Enzyme Inhibitors; Female; Hypotension; In Vitro Techniques; Lipopolysaccharides; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pseudomonas aeruginosa; Sepsis; Vasodilation; Vasodilator Agents

1998
Overexpression of eNOS in the RVLM causes hypotension and bradycardia via GABA release.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:4

    Topics: Adenoviridae; Animals; beta-Galactosidase; Blood Pressure; Bradycardia; Enzyme Inhibitors; gamma-Aminobutyric Acid; Gene Expression Regulation, Enzymologic; Gene Transfer Techniques; Genetic Vectors; Glutamic Acid; Heart Rate; Hypotension; Male; Medulla Oblongata; Microdialysis; Microinjections; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Norepinephrine; omega-N-Methylarginine; Rats; Rats, Inbred WKY; Recombinant Fusion Proteins; Time Factors

2001
Reversal of hypotension induced by Vibrio vulnificus lipopolysaccharide in the rat by inhibition of nitric oxide synthase.
    Microbial pathogenesis, 1992, Volume: 13, Issue:5

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Heart Rate; Hypotension; Lipopolysaccharides; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Vibrio

1992
Cardiovascular actions of NG-methyl-L-arginine are abolished in a canine shock model using high-dose endotoxin.
    Research communications in chemical pathology and pharmacology, 1992, Volume: 78, Issue:1

    Topics: Animals; Arginine; Blood Pressure; Cardiac Output; Disease Models, Animal; Dogs; Endotoxins; Escherichia coli; Heart; Hypotension; Lipopolysaccharides; Male; Nitric Oxide; omega-N-Methylarginine; Shock; Vascular Resistance; Vasoconstriction

1992
Inhibition in the rat of nitric oxide synthesis in vivo does not attenuate the hypotensive action of acetylcholine, ATP or bradykinin.
    Experimental physiology, 1992, Volume: 77, Issue:2

    Topics: Acetylcholine; Adenosine Triphosphate; Animals; Arginine; Bradykinin; Endothelium, Vascular; Glyburide; Hypotension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains

1992
Adenosine release in morphine-induced hypotension in rats.
    General pharmacology, 1992, Volume: 23, Issue:1

    Topics: 2-Chloroadenosine; Adenosine; Animals; Arginine; Blood Pressure; Dipyridamole; Hypotension; Injections, Intraperitoneal; Injections, Intravenous; Male; Morphine; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Tetrabenazine; Theophylline

1992
Protamine releases endothelium-derived relaxing factor from systemic arteries. A possible mechanism of hypotension during heparin neutralization.
    Circulation, 1992, Volume: 86, Issue:1

    Topics: Animals; Arginine; Arteries; Dogs; Endothelium, Vascular; Heparin; Hypotension; Nitric Oxide; omega-N-Methylarginine; Protamines; Stereoisomerism; Vasodilation

1992
NG-methyl-L-arginine inhibits tumor necrosis factor-induced hypotension: implications for the involvement of nitric oxide.
    Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:9

    Topics: Animals; Arginine; Blood Pressure; Dogs; Heart Rate; Hypotension; Nitric Oxide; omega-N-Methylarginine; Recombinant Proteins; Time Factors; Tumor Necrosis Factor-alpha

1990