omega-n-methylarginine has been researched along with Disease Models, Animal in 105 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 50 (47.62) | 18.2507 |
2000's | 45 (42.86) | 29.6817 |
2010's | 9 (8.57) | 24.3611 |
2020's | 1 (0.95) | 2.80 |
Authors | Studies |
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Jin, H; Jin, QH; Li, YS; Ren, P; Wang, LP; Xiao, B | 1 |
Dagley, A; Smee, DF; Tarbet, EB | 1 |
Belser, JA; Katz, JM; Perrone, LA; Tumpey, TM; Wadford, DA | 1 |
Asano, T; Hayakawa, M; Nakajima, F; Nakamura, H | 1 |
Bandara, G; Desai, A; Gilfillan, AM; Hox, V; Metcalfe, DD; Olivera, A | 1 |
Bishayi, B; Dey, S | 1 |
Addabbo, F; Bachmann, S; Goligorsky, MS; Paliege, A; Patschan, D; Ratliff, B; Stoessel, A; Theilig, F; Waschke, J | 1 |
Groszmann, RJ; Mehal, WZ; Ripoll, C; Zipprich, A | 1 |
Borda, E; Busch, L; Miozza, V; S-Borda, L | 1 |
Cerrato, R; Grönros, J; Jung, C; Lundberg, JO; Ostenson, CG; Pernow, J | 1 |
Li, YF; Mehta, PP; Patel, KP; Sharma, NM; Zheng, H | 1 |
Lazarovici, P; Lecht, S; Routhu, KV; Strande, JL | 1 |
Ikebe, K; Irie, H; Kato, T; Oniki, Y; Takagi, K; Tsuchida, T; Yamaga, M | 1 |
Goto, D; Iida, M; Iwase, M; Tashiro, K; Uchizono, Y | 1 |
Ando, A; Campochiaro, PA; Nambu, H; Yang, A | 1 |
Genda, S; Ichikawa, Y; Miki, T; Miura, T; Shimamoto, K | 1 |
Ardeschir Ghofrani, H; Fink, L; Gerigk, B; Grimminger, F; Gunther, A; Hänze, J; Nollen, M; Quanz, K; Rose, F; Schermuly, RT; Seeger, W; Weissmann, N | 1 |
Bahrami, S; Costantino, G; Duvigneau, JC; Gemeiner, M; Kozlov, AV; Nohl, H; Redl, H; Sobhian, B | 1 |
Arcucci, O; Bilancio, A; Chiariello, M; Coppola, C; Curcio, A; Falco, M; Indolfi, C; Leccia, A; Leosco, D; Rodriguez, F; Torella, D | 1 |
Inci, K; Ismailoglu, UB; Sahin, A; Sahin-Erdemli, I; Sungur, A | 1 |
Kamiyama, Y; Kitade, H; Kwon, AH; Okumura, T; Satoi, S; Tu, W; Zhang, Z | 1 |
Cox, R; Enkhbaatar, P; Hawkins, H; Herndon, D; Jodoin, J; Lee, S; McGuire, R; Mizutani, A; Murakami, K; Schmalstieg, F; Shimoda, K; Traber, D; Traber, L | 1 |
Buikema, H; de Zeeuw, D; Gschwend, S; Henning, RH; Pinto, YM; van Gilst, WH | 1 |
Cao, H; Chen, XS; Wu, ZY | 1 |
Bergmeier, W; Cambien, B; Mitchell, HA; Saffaripour, S; Wagner, DD | 1 |
Hirooka, Y; Kimura, Y; Kishi, T; Shigematsu, H; Takeshita, A; Ueta, Y | 1 |
Alonso, MJ; González, R; Martínez-Orgado, J; Salaices, M | 1 |
Gilkeson, GS; Oates, JC | 1 |
Slomiany, A; Slomiany, BL | 1 |
Kawakami, K; Kawakami, M; Puri, RK | 1 |
Fujita, T; Kamisaki, Y; Yonehara, N | 1 |
Jian, MY; Koizumi, T; Kubo, K | 1 |
Aubier, M; Boczkowski, J; Cisse, F; Danialou, G; Lanone, S; Samb, A | 1 |
Glatzle, J; Habermann, FM; Kreis, ME; Meile, T; Zittel, TT | 1 |
Mayr, FB; Spiel, AO | 1 |
Boer, R; Ghofrani, HA; Grimminger, F; Lehner, M; Maring, D; Mayer, K; Pullamsetti, SS; Rosengarten, B; Schermuly, RT; Schudt, C; Seeger, W; Weissmann, N | 1 |
Hong, CY; Hsiao, M; Kok, SH; Kuo, MY; Lin, CT; Lin, LD; Lin, SK; Wang, CC | 1 |
Scher, RL | 1 |
Bzhozovs'kyĭ, T; Hzhehots'kyĭ, MR; Konturek, SIa; Slivovs'kyĭ, Z; Zaiachkivs'ka, OS | 1 |
Baker, JE; Fu, X; Gross, GJ; Hsu, A; Strande, JL; Su, J | 1 |
Chelly, B; Chelly, JE; Doursout, MF; Fischer, UM; Hartley, CJ; Liang, Y; Oguchi, T | 1 |
Ning, J; Titheradge, MA; Wallington, J | 1 |
Garside, P; Liew, FY; Mowat, AM; Severn, A | 1 |
Currie, MG; Masferrer, JL; Misko, TP; Needleman, P; Salvemini, D; Seibert, K | 1 |
Coffey, JW; Evans, CH; Hoffman, RA; Meschter, C; Meyers, K; Stefanovic-Racic, M | 1 |
Grinstein, S; Orn, A; Petray, P; Rottenberg, ME | 1 |
Cheng, W; Cunningham, JN; Damiani, P; Henderson, JL; Horovitz, JH; Siconolfi, A; Statman, R | 1 |
Economidou, D; Leontsini, M; Margari, P; Papadimitriou, M; Raidis, C; Vakianis, P; Vrettos, M | 1 |
Agarwal, N; Chalasani, S; Lentz, KE; Lomis, TJ; Lowenstein, CJ; McMillan, A; Rhoads, JE; Siffring, CW; Stauffer, KE; Ziegler, DW | 1 |
Heidbreder, E; Heidland, A; Kartenbender, K; Ling, H; Schmitt, A; Schramm, L; Zimmermann, J | 1 |
Broner, CW; O'Dorisio, MS; O'Dorisio, TM; Rosenberg, RB | 1 |
Lupini, M; Mannaioni, PF; Masini, E; Mugnai, L; Raspanti, S | 1 |
Chamulitrat, W; Jordan, SJ; Litton, AL; Mason, RP; Molina y Vedia, L; Wilson, JG; Wolberg, G; Wood, ER | 1 |
Badr, KF; Ferrario, R; Fogo, A; Munger, KA; Takahashi, K | 1 |
Campbell, C; Napolitano, LM | 1 |
Aldras, AM; Bohm, R; Didier, ES; Didier, PJ; Millichamp, NJ; Murphey-Corb, M; Shadduck, JA; Varner, PW | 1 |
Klabunde, RE; Ritger, RC; Slayton, KJ | 1 |
Baudouin, SV; Evans, TW | 1 |
Thiemermann, C | 1 |
Béa, ML; Berdeaux, A; Ghaleh, B; Giudicelli, JF; Puybasset, L; Simon, L | 1 |
Bennett, T; Gardiner, SM; Kemp, PA; March, JE | 1 |
Fukatsu, K; Fukushima, R; Furukawa, S; Han, I; Inaba, T; Inoue, T; Lin, MT; Muto, T; Saito, H | 1 |
Booke, M; Hinder, F; McGuire, R; Traber, DL; Traber, LD | 1 |
Charles, CJ; Fitzpatrick, MA; Frampton, CM; Ikram, H; Nicholls, MG; Rademaker, MT; Richards, AM | 1 |
Daughters, K; Nguyen, H; Waxman, K | 1 |
Adams, HR; Gupta, M; Mattox, ML; Myers, PR; Parker, JL; Rogers, S | 1 |
Hurst, T; Johnson, D; Mayers, I | 1 |
Finkelstein, SD; Madhere, SM; Pricolo, VE; Reichner, JS | 1 |
Breslin, E; Cawley, T; Docherty, JR; Geraghty, J; Osborne, H | 1 |
Moriya, H; Nakaya, H; Nemoto, T; Sekikawa, T; Suzuki, T | 1 |
Phillips, RS; Severn, A; Taylor-Robinson, AW | 1 |
Bone, HG; Deyo, DJ; Fischer, SR; McGuire, R; Traber, DL; Traber, LD | 1 |
Baron, AD; Fei, L; Henry, DP; Zipes, DP | 1 |
Azzadin, A; Buczko, W; Chabielska, E; Famulski, W; Pawlak, R | 1 |
Deitch, EA; Lu, Q; Mishima, S; Xu, D | 1 |
Cox, FE | 1 |
Giercksky, KE; Kirkebøen, KA; Leone, AM; Skovlund, E; Strand, OA | 1 |
Comtois, A; Ebihara, S; El Dwairi, Q; Gottfried, SB; Hussain, SN; Lin, MC; Petrof, BJ; Yang, L | 1 |
Di Maria, GU; Fabbri, LM; Geppetti, P; Rado, V; Ricciardolo, FL; Sterk, PJ | 1 |
Chen, LE; Frankel, ES; Joneschild, ES; Seaber, AV; Urbaniak, JR | 1 |
Cobb, JP | 1 |
Deitch, EA; Mishima, S; Xu, D | 1 |
Bories, PN; Gadano, AC; Heller, J; Lebrec, D; Moreau, R; Sogni, P | 1 |
Armour, KE; Grabowski, PS; Ralston, SH; Reid, DM; Van'T Hof, RJ | 1 |
Doherty, JC; McMillen, MA | 1 |
Ito, M; Koyama, H; Maeda, T; Ohshige, A; Okamura, H; Yoshimura, T | 1 |
Chelly, JE; Doursout, MF; Hartley, CJ; Kilbourn, RG | 1 |
Akashi, K; Asayama, J; Fliss, H; Katamura, M; Kawahara, A; Keira, N; Kobara, M; Matoba, S; Nakagawa, C; Nakagawa, M; Ohta, B; Shiraishi, J; Shirayama, T; Takeda, K; Tanaka, T; Tatsumi, T | 1 |
Holt, PG; Sly, PD; Tulić, MK; Wale, JL | 1 |
Gilroy, DW; Paul-Clark, MJ; Tomlinson, A; Willis, D; Willoughby, DA | 1 |
Davidge, ST; Stewart, KG; Zhang, Y | 1 |
Hobbs, AJ; Hussain, MB; MacAllister, RJ | 1 |
Bossone, C; Hosseini, JM; Piñeiro-Carrero, V; Shea-Donohue, T | 1 |
Mathur, A; Saxena, SK; Srivastava, RC | 1 |
Li, YF; Patel, KP; Zhang, K | 1 |
Gandley, RE; Hubel, CA; Johnston, TP; McLaughlin, MK; Novak, J; Ramirez, RJ | 1 |
Hu, H; Liu, Y; Zhu, J | 1 |
Chen, Z; Jiao, Z; Kuang, Y; Wang, Q; Wu, Z; Yuan, J; Zeng, M; Zhou, H; Zhou, J | 1 |
Jackson, SK; James, PE; Madhani, M; Roebuck, W; Swartz, HM | 1 |
Azuma, H; Goto, M; Kihara, K; Masuda, H; Okuno, T; Tsujii, T | 1 |
Atkinson, AM; Teale, DM | 1 |
Billiar, TR; Curran, RD; Demetris, AJ; Harbrecht, BG; Ochoa, JB; Simmons, RL; Stadler, J | 1 |
Helgren, MC; Klabunde, RE | 1 |
Moncada, S; Rees, DD; Wright, CE | 1 |
Brezis, M; Dinour, D; Epstein, FH; Heyman, SN; Rosen, S | 1 |
2 review(s) available for omega-n-methylarginine and Disease Models, Animal
Article | Year |
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Selective inhibition of the activity of inducible nitric oxide synthase in septic shock.
Topics: Animals; Arginine; Disease Models, Animal; Enzyme Induction; Enzyme Inhibitors; Guanidines; Humans; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Shock, Septic; Thiourea | 1995 |
Use of nitric oxide synthase inhibitors to treat septic shock: the light has changed from yellow to red.
Topics: Animals; Clinical Trials, Phase III as Topic; Disease Models, Animal; Drug Evaluation, Preclinical; Hemodynamics; Humans; Nitric Oxide Synthase; omega-N-Methylarginine; Shock, Septic | 1999 |
1 trial(s) available for omega-n-methylarginine and Disease Models, Animal
Article | Year |
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N(G)-monomethyl-L-arginine improves survival in a pig model of abdominal sepsis.
Topics: Animals; Bacteremia; Critical Care; Disease Models, Animal; Enzyme Inhibitors; Hemodynamics; Nitrates; Nitric Oxide Synthase; omega-N-Methylarginine; Peritonitis; Prospective Studies; Random Allocation; Swine | 1998 |
102 other study(ies) available for omega-n-methylarginine and Disease Models, Animal
Article | Year |
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Nitric oxide impairs spatial learning and memory in a rat model of Alzheimer's disease via disturbance of glutamate response in the hippocampal dentate gyrus during spatial learning.
Topics: Alzheimer Disease; Animals; Behavior, Animal; Dentate Gyrus; Disease Models, Animal; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Maze Learning; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Ovariectomy; Rats; Rats, Sprague-Dawley | 2022 |
Combinations of L-N
Topics: Animals; Antiviral Agents; Disease Models, Animal; Drug Synergism; Enzyme Inhibitors; Female; Influenza A Virus, H1N1 Subtype; Mice; Mice, Inbred BALB C; omega-N-Methylarginine; Orthomyxoviridae Infections; Oseltamivir | 2017 |
Inducible nitric oxide contributes to viral pathogenesis following highly pathogenic influenza virus infection in mice.
Topics: Animals; Chemokines; Cytokines; Disease Models, Animal; Female; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H5N1 Subtype; Lung; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Nitric Oxide; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Orthomyxoviridae Infections; Pandemics | 2013 |
Reduction of nitric oxide with L-/NG-monomethyl arginine in interleukin-2 and anti-CD3 monoclonal antibody combination therapy.
Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; CD3 Complex; Cell Line, Tumor; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Female; Fibrosarcoma; Immunotherapy; Interleukin-2; Liver Neoplasms, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Nitric Oxide; omega-N-Methylarginine | 1996 |
Estrogen increases the severity of anaphylaxis in female mice through enhanced endothelial nitric oxide synthase expression and nitric oxide production.
Topics: Anaphylaxis; Animals; Body Temperature; Capillary Permeability; Disease Models, Animal; Estradiol; Estrogen Receptor Antagonists; Female; Gene Expression; Histamine; Humans; Lung; Male; Mast Cells; Mice; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Ovariectomy; Protein Aggregates; Receptors, Estrogen; Receptors, IgE; Receptors, IgG | 2015 |
Effect of iNOS inhibitor LNMMA along with antibiotics Chloramphenicol or Ofloxacin in murine peritoneal macrophages regulates S.aureus infection as well as inflammation: An in vitro study.
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Chloramphenicol; Cyclooxygenase 2; Cytokines; Disease Models, Animal; Hydrogen Peroxide; Inflammation; Macrophages, Peritoneal; Male; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; Ofloxacin; omega-N-Methylarginine; Oxygen; Random Allocation; Staphylococcal Infections; Staphylococcus aureus; Superoxide Dismutase; Superoxides; Toll-Like Receptor 2 | 2017 |
Indolent course of tubulointerstitial disease in a mouse model of subpressor, low-dose nitric oxide synthase inhibition.
Topics: Animals; Cells, Cultured; Disease Models, Animal; Endothelium, Vascular; Kidney; Kidney Diseases; Leukocytes; Mice; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Platelet Aggregation | 2008 |
A distinct nitric oxide and adenosine A1 receptor dependent hepatic artery vasodilatatory response in the CCl-cirrhotic liver.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Blotting, Western; Caffeine; Carbon Tetrachloride; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hepatic Artery; Liver Cirrhosis, Experimental; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Perfusion; Portal Vein; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptor, Adenosine A2A; Theophylline; Vascular Resistance; Vasodilation; Vasodilator Agents | 2010 |
Increase nitric oxide synthase activity in parotid glands from rats with experimental periodontitis.
Topics: Adenine; Amylases; Animals; Calcium; Cyclic AMP-Dependent Protein Kinase Catalytic Subunits; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Egtazic Acid; Enzyme Inhibitors; Guanidines; Indazoles; Indomethacin; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Organ Size; Ornithine; Parotid Gland; Periodontitis; Piperazines; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Salivary Proteins and Peptides; Thiazoles | 2010 |
Arginase inhibition restores in vivo coronary microvascular function in type 2 diabetic rats.
Topics: Amino Acids; Animals; Arginase; Arginine; Blood Flow Velocity; Blood Glucose; Coronary Circulation; Diabetes Mellitus, Type 2; Disease Models, Animal; Enzyme Inhibitors; Insulin; Male; Microvessels; Nitrites; omega-N-Methylarginine; Rats; Rats, Wistar | 2011 |
Decreased nNOS in the PVN leads to increased sympathoexcitation in chronic heart failure: role for CAPON and Ang II.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cell Line, Tumor; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Heart Failure; Hemodynamics; Immunohistochemistry; Kidney; Losartan; Male; Microinjections; Nitric Oxide Synthase Type I; omega-N-Methylarginine; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptors, N-Methyl-D-Aspartate; RNA Interference; RNA, Messenger; Sympathetic Nervous System; Time Factors | 2011 |
Nerve growth factor reduces myocardial ischemia/reperfusion injury in rat hearts.
Topics: Androstadienes; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Myocardial Reperfusion Injury; Nerve Growth Factor; Nitric Oxide Synthase; omega-N-Methylarginine; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Wortmannin | 2013 |
Effect of nitric oxide on the contractile function of rat reperfused skeletal muscle.
Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; Male; Muscle Contraction; Muscle, Skeletal; Nitric Oxide; Nitric Oxide Donors; omega-N-Methylarginine; Rats; Rats, Inbred Lew; Reperfusion Injury; S-Nitrosoglutathione | 2002 |
Islet hyperperfusion during prediabetic phase in OLETF rats, a model of type 2 diabetes.
Topics: Animals; Diabetes Mellitus, Type 2; Diet, Reducing; Dietary Sucrose; Disease Models, Animal; Insulin; Islets of Langerhans; Male; omega-N-Methylarginine; Pancreas; Perfusion; Prediabetic State; Rats; Rats, Inbred OLETF; Rats, Long-Evans; Regional Blood Flow; Species Specificity | 2002 |
Blockade of nitric-oxide synthase reduces choroidal neovascularization.
Topics: Animals; Bruch Membrane; Choroidal Neovascularization; Disease Models, Animal; Endothelial Growth Factors; Enzyme Inhibitors; Ischemia; Isoenzymes; Lymphokines; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Retinal Neovascularization; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2002 |
K(ATP) channel opening is an endogenous mechanism of protection against the no-reflow phenomenon but its function is compromised by hypercholesterolemia.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Chronic Disease; Coronary Circulation; Disease Models, Animal; Glyburide; Hemodynamics; Hypercholesterolemia; Male; Myocardial Infarction; Nicorandil; Nitric Oxide Synthase; omega-N-Methylarginine; Potassium Channel Blockers; Potassium Channels; Rabbits; Vasodilator Agents | 2002 |
Downregulation of hypoxic vasoconstriction by chronic hypoxia in rabbits: effects of nitric oxide.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acute Disease; Animals; Breath Tests; Chronic Disease; Disease Models, Animal; Enzyme Inhibitors; Female; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; In Vitro Techniques; Lung; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rabbits; Time; Vasoconstriction; Vasoconstrictor Agents | 2003 |
Nitric oxide synthase inhibitors affect nitric oxide synthesis in normoxic but not in ischemic organs during intestinal ischemia and early reperfusion.
Topics: Animals; Arginine; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Intestines; Liver; Lung; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2002 |
Physical training increases eNOS vascular expression and activity and reduces restenosis after balloon angioplasty or arterial stenting in rats.
Topics: Adenosine Diphosphate; Angioplasty, Balloon; Animals; Carotid Stenosis; Cell Division; Disease Models, Animal; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Graft Occlusion, Vascular; Hyperplasia; Immunoblotting; Immunohistochemistry; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Physical Conditioning, Animal; Physical Exertion; Platelet Aggregation; Rats; Rats, Wistar; Stents; Swimming; Tunica Intima | 2002 |
The effect of inflammation on rat urinary bladder-dependent relaxation in coaxial bioassay system.
Topics: Acetylcholine; Administration, Intravesical; Anal Canal; Animals; Biological Assay; Cyclophosphamide; Cystitis; Disease Models, Animal; Injections, Intraperitoneal; Lipopolysaccharides; Male; Muscle Proteins; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Wistar; Urinary Bladder; Urothelium | 2003 |
Hepatocellular dysfunction induced by nitric oxide production in hepatocytes isolated from rats with sepsis.
Topics: Adenosine Triphosphate; Animals; Arginine; Cecum; Disease Models, Animal; Enzyme Inhibitors; Hepatocytes; Humans; Interleukin-1; Intestinal Perforation; Ketone Bodies; Ligation; Liver Diseases; Male; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Wistar; Recombinant Proteins; Systemic Inflammatory Response Syndrome | 2003 |
Inhibition of neuronal nitric oxide synthase by 7-nitroindazole attenuates acute lung injury in an ovine model.
Topics: Acute Disease; Animals; Disease Models, Animal; Enzyme Inhibitors; Female; Guanidines; Indazoles; Lung Diseases; Nitric Oxide Synthase; omega-N-Methylarginine; Pneumonia, Bacterial; Sheep, Domestic; Smoke | 2003 |
Myogenic constriction is increased in mesenteric resistance arteries from rats with chronic heart failure: instantaneous counteraction by acute AT1 receptor blockade.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Bridged Bicyclo Compounds, Heterocyclic; Captopril; Chronic Disease; Coronary Vessels; Disease Models, Animal; Endothelium-Dependent Relaxing Factors; Endothelium, Vascular; Fatty Acids, Unsaturated; Heart; Heart Failure; Hydrazines; Imidazoles; Indomethacin; Lisinopril; Losartan; Male; Mesenteric Arteries; Nitric Oxide; omega-N-Methylarginine; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Superoxide Dismutase; Sympathetic Nervous System; Tetrazoles; Tetrodotoxin; Vascular Resistance | 2003 |
[The effect of PGI2 on formation and development of hyperdynamic circulatory state in portal hypertensive rats].
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cyclooxygenase Inhibitors; Disease Models, Animal; Enzyme Inhibitors; Epoprostenol; Hemodynamics; Hypertension, Portal; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Random Allocation; Rats; Rats, Sprague-Dawley | 2003 |
Antithrombotic activity of TNF-alpha.
Topics: Animals; Arteries; Blood Coagulation; Blood Platelets; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibrinolytic Agents; Hemodynamics; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; P-Selectin; Receptors, Tumor Necrosis Factor; Thrombosis; Time Factors; Tumor Necrosis Factor-alpha | 2003 |
Reduced nitric oxide synthase in the brainstem contributes to enhanced sympathetic drive in rats with heart failure.
Topics: Animals; Blood Pressure; Blotting, Western; Brain Stem; Disease Models, Animal; Echocardiography; Gene Expression; Heart Failure; Hemodynamics; In Situ Hybridization; Injections, Intraventricular; Male; Myocardial Infarction; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Norepinephrine; omega-N-Methylarginine; Organ Size; Rats; Rats, Inbred WKY; RNA, Messenger; Solitary Nucleus; Sympathetic Nervous System | 2003 |
Impairment of fetal endothelium-dependent relaxation in a rat model of preeclampsia by chronic nitric oxide synthase inhibition.
Topics: Acetylcholine; Animals; Arginine; Dinoprost; Disease Models, Animal; Enzyme Inhibitors; Female; Fetus; Muscle Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; omega-N-Methylarginine; Potassium Chloride; Pre-Eclampsia; Pregnancy; Rats; Rats, Wistar; Vasodilation | 2004 |
Nitric oxide induces apoptosis in spleen lymphocytes from MRL/lpr mice.
Topics: Animals; Apoptosis; Disease Models, Animal; Enzyme Inhibitors; Female; Lupus Erythematosus, Systemic; Lymphocytes; Mice; Mice, Inbred BALB C; Mice, Inbred MRL lpr; Nitric Oxide; omega-N-Methylarginine; Spleen | 2004 |
Platelet-activating factor mediates Porphyromonas gingivalis lipopolysaccharide interference with salivary mucin synthesis via phosphatidylinositol 3-kinase-dependent constitutive nitric-oxide synthase activation.
Topics: Amidines; Androstadienes; Animals; Apoptosis; Benzylamines; Cell Survival; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Ginkgolides; Glucosamine; Lactones; Lipopolysaccharides; Mucins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Platelet Activating Factor; Porphyromonas gingivalis; Rats; Rats, Sprague-Dawley; Saliva; Salivary Glands; Sublingual Gland; Tritium; Tumor Necrosis Factor-alpha; Up-Regulation; Wortmannin | 2004 |
Nitric oxide accelerates interleukin-13 cytotoxin-mediated regression in head and neck cancer animal model.
Topics: Animals; Blotting, Western; Cell Line, Tumor; Cytotoxins; Disease Models, Animal; Drug Synergism; Enzyme Inhibitors; Exotoxins; Head and Neck Neoplasms; Humans; Immunohistochemistry; Immunotoxins; Interleukin-13; Macrophages; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms; Nitric Oxide; omega-N-Methylarginine; Recombinant Fusion Proteins | 2004 |
Nitric oxide-induced increase of excitatory amino acid levels in the trigeminal nucleus caudalis of the rat with tactile hypersensitivity evoked by the loose-ligation of the inferior alveolar nerves.
Topics: Animals; Aspartic Acid; Benzoates; Capsaicin; Dental Pulp; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acids; Glutamic Acid; Hyperalgesia; Imidazoles; Injections, Subcutaneous; Ligation; Lip; Male; Mandibular Nerve; Microdialysis; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Trigeminal Nuclei | 2004 |
Effects of nitric oxide synthase inhibitor on acid aspiration-induced lung injury in rats.
Topics: Amidines; Animals; Bronchoalveolar Lavage Fluid; Cell Count; Disease Models, Animal; Enzyme Inhibitors; Extravascular Lung Water; Heterocyclic Compounds, 2-Ring; Hydrochloric Acid; Interleukin-1; Japan; Lung; Lung Injury; Neutrophils; Nitric Oxide Synthase; omega-N-Methylarginine; Pneumonia, Aspiration; Rats; Rats, Sprague-Dawley; Serum Albumin; Spectrophotometry; Tumor Necrosis Factor-alpha | 2005 |
[Role of nitric oxide in diaphragmatic dysfunction genesis during sepsis in rats].
Topics: Animals; Anti-Inflammatory Agents; Biopsy; Cyclic GMP; Dexamethasone; Disease Models, Animal; Endotoxemia; Enzyme-Linked Immunosorbent Assay; Escherichia coli Infections; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Random Allocation; Rats; Rats, Sprague-Dawley; Respiratory Mechanics; Respiratory Paralysis | 2000 |
Nitric oxide synthase inhibition results in immediate postoperative recovery of gastric, small intestinal and colonic motility in awake rats.
Topics: Animals; Colon; Disease Models, Animal; Enzyme Inhibitors; Gastrointestinal Motility; Ileus; Intestine, Small; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Postoperative Period; Rats; Rats, Sprague-Dawley; Recovery of Function; Stomach | 2006 |
NO-synthase inhibition in sepsis.
Topics: Amidines; Animals; Benzylamines; Disease Models, Animal; Enzyme Inhibitors; Hemodynamics; Humans; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Sepsis; Shock, Septic | 2006 |
Effect of nitric oxide synthase (NOS) inhibition on macro- and microcirculation in a model of rat endotoxic shock.
Topics: Amidines; Animals; Benzylamines; Disease Models, Animal; Enzyme Inhibitors; Epinephrine; Hemoglobins; Male; Microcirculation; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Rats; Rats, Wistar; Shock, Septic | 2006 |
Nitric oxide promotes the progression of periapical lesion via inducing macrophage and osteoblast apoptosis.
Topics: Animals; Apoptosis; Cell Line; Cells, Cultured; Disease Models, Animal; Disease Progression; Drug Synergism; Enzyme Inhibitors; Free Radical Scavengers; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type II; Nitrites; omega-N-Methylarginine; Osteoblasts; Periapical Diseases; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Wistar; RNA, Small Interfering; S-Nitroso-N-Acetylpenicillamine | 2007 |
Role of nitric oxide in the development of distant metastasis from squamous cell carcinoma.
Topics: Animals; Arginine; Carcinoma, Squamous Cell; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Shape; Disease Models, Animal; Endothelium-Dependent Relaxing Factors; Enzyme Inhibitors; Fluorescent Dyes; Head and Neck Neoplasms; Humans; Interleukin-1; Liver Circulation; Mice; Mice, Inbred BALB C; Mice, Nude; Microcirculation; Microscopy, Video; Muscle, Skeletal; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Nude | 2007 |
[The cytokine profile during experimental esophagitis and modification of cytoprotective mechanisms].
Topics: Animals; Cyclooxygenase Inhibitors; Cytokines; Cytoprotection; Disease Models, Animal; Esophagitis; Male; Melatonin; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pepsin A; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar | 2006 |
SCH 79797, a selective PAR1 antagonist, limits myocardial ischemia/reperfusion injury in rat hearts.
Topics: Androstadienes; Animals; Cardiotonic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glyburide; Hirudins; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Oligopeptides; omega-N-Methylarginine; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Potassium Channel Blockers; Potassium Channels; Proto-Oncogene Proteins c-akt; Pyrroles; Quinazolines; Rats; Rats, Sprague-Dawley; Receptor, PAR-1; Recombinant Proteins; Research Design; RNA, Messenger; Signal Transduction; Thrombin; Time Factors; Ventricular Function, Left; Wortmannin | 2007 |
Distribution of NOS isoforms in a porcine endotoxin shock model.
Topics: Animals; Cardiomyopathies; Coronary Circulation; Disease Models, Animal; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Guanidines; Hemodynamics; Hypotension; Isoenzymes; Lipopolysaccharides; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Organ Specificity; Shock, Septic; Swine; Vasoconstriction; Vasodilation; Vasodilator Agents | 2008 |
The control of hepatic glycogen metabolism in an in vitro model of sepsis.
Topics: Adenylate Kinase; Animals; Cytokines; Disease Models, Animal; Glucose; Glucose-6-Phosphate; Glycogen Phosphorylase; Glycogen Synthase; Glycogen Synthase Kinase 3; Glycogenolysis; Humans; Lactic Acid; Lipopolysaccharides; Liver; Liver Glycogen; Male; omega-N-Methylarginine; Phosphorylation; Protein Kinases; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Sepsis; Uridine Diphosphate Glucose | 2008 |
The role of nitric oxide in enteropathy.
Topics: Animals; Arginine; Disease Models, Animal; Enzyme Inhibitors; Graft vs Host Reaction; Hyperplasia; Hypertrophy; Intestinal Diseases; Intestinal Mucosa; Mice; Nitric Acid; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Spleen; Transplantation, Homologous | 1995 |
Endogenous nitric oxide enhances prostaglandin production in a model of renal inflammation.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cholic Acids; Dinoprostone; Disease Models, Animal; Hydronephrosis; In Vitro Techniques; Indomethacin; Kidney; Male; Models, Biological; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Perfusion; Prostaglandin-Endoperoxide Synthases; Rabbits; Ureter | 1994 |
N-monomethyl arginine, an inhibitor of nitric oxide synthase, suppresses the development of adjuvant arthritis in rats.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Arthritis, Experimental; Disease Models, Animal; Male; Nitrates; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rats; Rats, Inbred Lew | 1994 |
Release of nitric oxide during the experimental infection with Trypanosoma cruzi.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Base Sequence; Chagas Disease; Disease Models, Animal; DNA Primers; Female; Interferon-gamma; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Peritoneal Cavity; RNA, Messenger; Spleen; Trypanosoma cruzi; Virulence | 1994 |
The effects of nitric oxide inhibition on regional hemodynamics during hyperdynamic endotoxemia.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bacteremia; Blood Gas Analysis; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Escherichia coli Infections; Hemodynamics; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Sepsis | 1994 |
Effect of inhibition of nitric oxide synthase in acute renal failure due to endotoxin shock in dogs.
Topics: Acute Kidney Injury; Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Disease Models, Animal; Dogs; Hemodynamics; Kidney; Lipopolysaccharides; Liver; Nitric Oxide Synthase; omega-N-Methylarginine; Shock, Septic | 1994 |
First place winner of the Conrad Jobst Award in the gold medal paper competition. Nitric oxide synthase inhibitors N-monomethylarginine and aminoguanidine prevent the progressive and severe hypotension associated with a rat model of pancreatitis.
Topics: Amylases; Animals; Arginine; Blood Pressure; Calcium; Clinical Protocols; Disease Models, Animal; Drug Evaluation, Preclinical; Fluid Therapy; Guanidines; Humans; Hypotension; Immunohistochemistry; Male; Multiple Organ Failure; Nitric Oxide; omega-N-Methylarginine; Pancreatitis; Premedication; Rats; Rats, Sprague-Dawley; Resuscitation; Severity of Illness Index | 1995 |
Role of L-arginine-derived NO in ischemic acute renal failure in the rat.
Topics: Acute Kidney Injury; Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Disease Models, Animal; Female; Glomerular Filtration Rate; Ischemia; Kidney; Natriuresis; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Urodynamics | 1994 |
Cyclic nucleotides and vasoactive intestinal peptide production in a rabbit model of Escherichia coli septicemia.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bacteremia; Blood Pressure; Cyclic AMP; Cyclic GMP; Disease Models, Animal; Escherichia coli Infections; Heart Rate; Lactates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rabbits; Reference Values; Vasoactive Intestinal Peptide | 1995 |
Polydeoxyribonucleotides and nitric oxide release from guinea-pig hearts during ischaemia and reperfusion.
Topics: Acetylcholine; Animals; Arginine; Arrhythmias, Cardiac; Chemical Fractionation; Coronary Circulation; Disease Models, Animal; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibrinolytic Agents; Guinea Pigs; Male; Molecular Weight; Myocardial Reperfusion Injury; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Polydeoxyribonucleotides | 1995 |
Targets of nitric oxide in a mouse model of liver inflammation by Corynebacterium parvum.
Topics: Animals; Arginine; Blood; Blotting, Western; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Heme; Hemoglobins; Inflammation; Liver; Liver Diseases; Male; Mice; Nitric Oxide; omega-N-Methylarginine; Propionibacterium acnes | 1995 |
Consequences of acute nitric oxide synthesis inhibition in experimental glomerulonephritis.
Topics: Animals; Arginine; Disease Models, Animal; Glomerulonephritis; Male; Neutrophils; Nitric Oxide; omega-N-Methylarginine; Proteinuria; Rats; Rats, Wistar; Renal Circulation | 1994 |
Nitric oxide inhibition normalizes splenocyte interleukin-10 synthesis in murine thermal injury.
Topics: Alcoholism; Animals; Arginine; Burns; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Interferon-gamma; Interleukin-10; Lymphocyte Activation; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitrites; omega-N-Methylarginine; Random Allocation; Spleen | 1994 |
Experimental microsporidiosis in immunocompetent and immunodeficient mice and monkeys.
Topics: Animals; Antibodies, Protozoan; Arginine; Cytokines; Disease Models, Animal; Encephalitozoon; Encephalitozoonosis; Female; Immunocompetence; Interferon-gamma; Lipopolysaccharides; Macaca mulatta; Macrophages, Peritoneal; Mice; Mice, Inbred Strains; Microsporidiosis; Nitric Oxide; Nosema; omega-N-Methylarginine; Opportunistic Infections; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus | 1994 |
NG-methyl-L-arginine restores arterial pressure in hemorrhaged rats.
Topics: Animals; Arginine; Arteries; Blood Pressure; Disease Models, Animal; Hypotension; Male; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; Vascular Resistance | 1993 |
Action of carbon dioxide on hypoxic pulmonary vasoconstriction in the rat lung: evidence against specific endothelium-derived relaxing factor-mediated vasodilation.
Topics: Angiotensin II; Animals; Arginine; Blood Gas Analysis; Carbon Dioxide; Constriction, Pathologic; Disease Models, Animal; Drug Evaluation, Preclinical; Hypercapnia; Hypoxia; Male; Nitric Oxide; omega-N-Methylarginine; Pulmonary Circulation; Pulmonary Wedge Pressure; Random Allocation; Rats; Rats, Wistar; Respiration, Artificial; Vascular Resistance | 1993 |
[Hemodynamic effects of sub-chronic NO synthase inhibition in conscious dogs: role of EDRF/NO in muscular exertion].
Topics: Acetylcholine; Animals; Arginine; Consciousness; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hemodynamics; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Physical Exertion | 1995 |
Cardiac and regional haemodynamics, inducible nitric oxide synthase (NOS) activity, and the effects of NOS inhibitors in conscious, endotoxaemic rats.
Topics: Animals; Arginine; Cardiac Output; Disease Models, Animal; Enzyme Induction; Hemodynamics; Hypotension; Lipopolysaccharides; Lung; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Reproducibility of Results; Stroke Volume; Tachycardia | 1995 |
Effects of three inhibitors of nitric oxide synthase on host resistance to bacterial infection.
Topics: Animals; Arginine; Disease Models, Animal; Enzyme Inhibitors; Escherichia coli Infections; Female; Mice; Mice, Inbred BALB C; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Ornithine; Prospective Studies; Random Allocation | 1996 |
Nitric oxide synthase inhibition versus norepinephrine for the treatment of hyperdynamic sepsis in sheep.
Topics: Animals; Arginine; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Inhibitors; Female; Hemodynamics; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Oxygen Consumption; Prospective Studies; Sepsis; Sheep; Time Factors; Vasoconstrictor Agents | 1996 |
Nitric oxide inhibition in an ovine model of heart failure.
Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; Female; Heart Failure; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Sheep | 1996 |
Increasing nitric oxide production improves survival in experimental hemorrhagic shock.
Topics: Analysis of Variance; Animals; Arginine; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Male; Nitric Oxide; omega-N-Methylarginine; Prospective Studies; Random Allocation; Rats; Rats, Sprague-Dawley; Resuscitation; Shock, Hemorrhagic | 1996 |
Chronic endotoxemia and endothelium-dependent vasodilation in coronary arteries.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Body Temperature; Body Weight; Chronic Disease; Coronary Vessels; Disease Models, Animal; Endothelium, Vascular; Endotoxemia; Hemodynamics; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; omega-N-Methylarginine; Rabbits; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 1996 |
Augmentation of hypoxic pulmonary vasoconstriction by N(G)-L-methyl-arginine in a rabbit model of thermal injury.
Topics: Animals; Burns; Disease Models, Animal; Enzyme Inhibitors; Hemodynamics; Hypoxia; Nitric Oxide Synthase; omega-N-Methylarginine; Pulmonary Artery; Rabbits; Vasoconstriction | 1996 |
Effects of lambda-carrageenan induced experimental enterocolitis on splenocyte function and nitric oxide production.
Topics: Animals; Carrageenan; Disease Models, Animal; Enterocolitis; Inflammatory Bowel Diseases; Lymphocyte Activation; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Spleen | 1996 |
Investigations of the function of the vascular endothelium in portal hypertensive rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Analysis of Variance; Animals; Coloring Agents; Disease Models, Animal; Endothelium, Vascular; Hypertension, Portal; Male; Mesenteric Arteries; Methylene Blue; Microspheres; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Wistar; Thromboxane A2; Vasoconstrictor Agents | 1995 |
Inhibition of nitric oxide synthesis accelerates the recovery of polysynaptic reflex potentials after transient spinal cord ischemia in cats.
Topics: Animals; Cats; Disease Models, Animal; Female; Ischemia; Male; Nitric Oxide; omega-N-Methylarginine; Reflex; Spinal Cord Diseases; Synaptic Transmission | 1997 |
Kinetics of nitric oxide production during infection and reinfection of mice with Plasmodium chabaudi.
Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; Humans; Immune Tolerance; Kinetics; Malaria; Mice; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Parasitemia; Plasmodium chabaudi | 1996 |
Nitric oxide synthase inhibition restores hypoxic pulmonary vasoconstriction in sepsis.
Topics: Animals; Constriction, Pathologic; Disease Models, Animal; Female; Hemodynamics; Hypoxia; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pseudomonas Infections; Pulmonary Artery; Pulmonary Circulation; Pulmonary Wedge Pressure; Sepsis; Sheep; Ultrasonography | 1997 |
Intrapericardial delivery of L-arginine reduces the increased severity of ventricular arrhythmias during sympathetic stimulation in dogs with acute coronary occlusion: nitric oxide modulates sympathetic effects on ventricular electrophysiological properti
Topics: Animals; Arginine; Confounding Factors, Epidemiologic; Disease Models, Animal; Dogs; Electric Stimulation; Enzyme Inhibitors; Myocardial Contraction; Myocardial Infarction; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Pericardium; Severity of Illness Index; Tachycardia, Ventricular | 1997 |
Cardiac side effects of L-NMMA.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heart; Hemodynamics; Humans; Infusions, Intravenous; Male; omega-N-Methylarginine; Rats; Rats, Wistar | 1998 |
The relationships among nitric oxide production, bacterial translocation, and intestinal injury after endotoxin challenge in vivo.
Topics: Animals; Bacterial Translocation; Disease Models, Animal; Drug Evaluation, Preclinical; Intestinal Mucosa; Lipopolysaccharides; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Random Allocation; Rats; Rats, Sprague-Dawley | 1998 |
Killing of blood stage Plasmodium vinckei petteri by spleen macrophages through L-arginine dependent mechanism.
Topics: Animals; Arginine; BCG Vaccine; Cells, Cultured; Disease Models, Animal; Female; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mice, Inbred BALB C; omega-N-Methylarginine; Plasmodium; Rodentia; Spleen; Time Factors | 1997 |
Diaphragm sarcolemmal injury is induced by sepsis and alleviated by nitric oxide synthase inhibition.
Topics: Animals; Blotting, Western; Cecal Diseases; Cell Membrane Permeability; Coloring Agents; Diaphragm; Disease Models, Animal; Endotoxins; Enzyme Inhibitors; Escherichia coli; Intestinal Perforation; Lipopolysaccharides; Male; Membrane Potentials; Muscle Contraction; Muscle Fibers, Skeletal; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Peritonitis; Rats; Rats, Sprague-Dawley; Sarcolemma; Sepsis | 1998 |
Bronchoconstriction induced by citric acid inhalation in guinea pigs: role of tachykinins, bradykinin, and nitric oxide.
Topics: Administration, Inhalation; Adrenergic beta-Antagonists; Airway Resistance; Animals; Asthma; Benzamides; Bradykinin; Bradykinin Receptor Antagonists; Bronchoconstriction; Citric Acid; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme Inhibitors; Guinea Pigs; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Piperidines; Receptors, Neurokinin-2 | 1999 |
Effect of a NOS inhibitor, L-NMMA, on the contractile function of reperfused skeletal muscle.
Topics: Analysis of Variance; Animals; Culture Techniques; Disease Models, Animal; Enzyme Inhibitors; Male; Muscle Contraction; Muscle, Skeletal; Nitric Oxide Synthase; omega-N-Methylarginine; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sensitivity and Specificity | 1999 |
Increase in endotoxin-induced mucosal permeability is related to increased nitric oxide synthase activity using the Ussing chamber.
Topics: Animals; Bacterial Translocation; Cell Membrane Permeability; Disease Models, Animal; Escherichia coli; Ileum; In Vitro Techniques; Intestinal Mucosa; Lipopolysaccharides; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Time Factors | 1999 |
Vascular nitric oxide production during the development of two experimental models of portal hypertension.
Topics: Animals; Aorta, Thoracic; Disease Models, Animal; Guanidines; Hypertension, Portal; In Vitro Techniques; Liver Cirrhosis, Biliary; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Norepinephrine; omega-N-Methylarginine; Portal Vein; Rats; Rats, Sprague-Dawley; Sulfonamides; Thrombosis | 1999 |
Evidence for a pathogenic role of nitric oxide in inflammation-induced osteoporosis.
Topics: Animals; Bone Density; Disease Models, Animal; Enzyme Activation; Female; Histocytochemistry; Inflammation; Magnesium Silicates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Osteoblasts; Osteoclasts; Osteoporosis; Rats; Rats, Sprague-Dawley | 1999 |
Use of animal models to test novel therapies in sepsis.
Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; omega-N-Methylarginine; Sepsis; Swine | 2000 |
Nitric oxide affects angiotensin II pressor response: possible mechanism of attenuated pressor response during pregnancy and etiology of pregnancy-induced hypertension.
Topics: Angiotensin II; Animals; Arginine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme Inhibitors; Female; Hypertension; Injections, Intraperitoneal; Nitric Oxide; omega-N-Methylarginine; Pregnancy; Pregnancy Complications, Cardiovascular; Pressoreceptors; Probability; Rats; Rats, Wistar; Reference Values; Sensitivity and Specificity; Software; Vasoconstrictor Agents | 2000 |
Effects of N-methyl-L-arginine on cardiac and regional blood flow in a dog endotoxin shock model.
Topics: Animals; Coronary Vessels; Disease Models, Animal; Dogs; Enzyme Inhibitors; Nitric Oxide Synthase; omega-N-Methylarginine; Regional Blood Flow; Shock, Septic; Vascular Resistance | 2000 |
Cytokine-induced nitric oxide production inhibits mitochondrial energy production and impairs contractile function in rat cardiac myocytes.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Cells, Cultured; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Energy Metabolism; Glucose; Glycolysis; Inflammation; Interleukin-1; Lactic Acid; Mitochondria, Heart; Myocardial Contraction; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Rats | 2000 |
Differential effects of nitric oxide synthase inhibitors in an in vivo allergic rat model.
Topics: Animals; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Citrulline; Disease Models, Animal; Enzyme Inhibitors; Guanidines; Hypersensitivity; Male; Methacholine Chloride; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Thiourea | 2000 |
Nitric oxide synthase inhibitors have opposite effects on acute inflammation depending on their route of administration.
Topics: Acute Disease; Amidines; Animals; Antioxidants; Benzylamines; Carrageenan; Disease Models, Animal; Drug Administration Schedule; Edema; Enzyme Inhibitors; Free Radical Scavengers; Inflammation; Inflammation Mediators; Injections; Injections, Intraperitoneal; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Pleura; Pleurisy; Rats; Rats, Wistar; Superoxides; Thiourea | 2001 |
Endogenous estrogen mediates vascular reactivity and distensibility in pregnant rat mesenteric arteries.
Topics: Adaptation, Physiological; Animals; Blotting, Western; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Estrogen Antagonists; Estrogens; Female; Mesenteric Arteries; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; omega-N-Methylarginine; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Tamoxifen; Vasodilation; Vasodilator Agents | 2001 |
Reciprocal regulation of cGMP-mediated vasorelaxation by soluble and particulate guanylate cyclases.
Topics: Animals; Aorta; Atrial Natriuretic Factor; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Homeostasis; Humans; Mammary Arteries; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrogen Oxides; Nitroglycerin; omega-N-Methylarginine; Phenylephrine; Solubility; Spermine; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2001 |
Alterations in spontaneous contractions in vitro after repeated inflammation of rat distal colon.
Topics: Animals; Colitis; Colon; Disease Models, Animal; Gastrointestinal Motility; Guanidines; In Vitro Techniques; Inflammation; Inflammatory Bowel Diseases; Male; Muscle Contraction; Muscle, Smooth; NADPH Dehydrogenase; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Tetrodotoxin; Time Factors; Trinitrobenzenesulfonic Acid | 2001 |
Induction of nitric oxide synthase during Japanese encephalitis virus infection: evidence of protective role.
Topics: Animals; Brain; Disease Models, Animal; Encephalitis Virus, Japanese; Encephalitis, Japanese; Enzyme Inhibitors; Immunoblotting; Macrophage-Activating Factors; Mice; Mortality; Nitric Oxide Synthase; omega-N-Methylarginine; Tumor Necrosis Factor-alpha; Virus Replication | 2001 |
Blunted nitric oxide-mediated inhibition of renal nerve discharge within PVN of rats with heart failure.
Topics: Animals; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heart Failure; Heart Rate; Kidney; Ligation; Male; Microinjections; Neural Inhibition; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System | 2001 |
Endothelial function and myogenic reactivity in small mesenteric arteries of hyperlipidemic pregnant rats.
Topics: Animals; Blood Pressure; Cholesterol; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Fatty Acids, Nonesterified; Female; Fetal Weight; Hyperlipidemias; Malondialdehyde; Mesenteric Arteries; omega-N-Methylarginine; Poloxamer; Pregnancy; Pregnancy Complications; Rats; Rats, Sprague-Dawley; Triglycerides; Vasoconstrictor Agents; Vasodilator Agents; Vasomotor System | 2001 |
[Effects of relative imbalance between endothlin-1 and nitric oxide on pathogenesis of the ascaris-induced asthma in dogs].
Topics: Animals; Arginine; Ascaris; Asthma; Disease Models, Animal; Dogs; Endothelin-1; Enzyme Inhibitors; Female; Infusions, Intravenous; Male; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine | 1999 |
[The role of nitric oxide in hyperdynamic circulation in portal hypertensive rats].
Topics: Animals; Arginine; Carbon Tetrachloride; Disease Models, Animal; Enzyme Inhibitors; Hemodynamics; Hypertension, Portal; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Portasystemic Shunt, Surgical; Rats; Rats, Sprague-Dawley | 1998 |
Endotoxin-induced liver hypoxia: defective oxygen delivery versus oxygen consumption.
Topics: Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Endotoxins; Hemodynamics; Hypoxia; Interleukin-13; Lipopolysaccharides; Liver Diseases; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; omega-N-Methylarginine; Oxygen; Partial Pressure; Shock, Septic | 2002 |
Accumulated endogenous NOS inhibitors, decreased NOS activity, and impaired cavernosal relaxation with ischemia.
Topics: Animals; Arginine; Calcium; Carbachol; Cholinergic Agonists; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Endothelium, Vascular; Enzyme Inhibitors; Iliac Artery; Impotence, Vasculogenic; In Vitro Techniques; Ischemia; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Penis; Rabbits; Vasoconstrictor Agents; Vasodilator Agents | 2002 |
Inhibition of nitric oxide synthesis improves survival in a murine peritonitis model of sepsis that is not cured by antibiotics alone.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cilastatin; Cilastatin, Imipenem Drug Combination; Disease Models, Animal; Drug Combinations; Drug Therapy, Combination; Escherichia coli Infections; Imipenem; Male; Mice; Nitric Oxide Synthase; omega-N-Methylarginine; Peritonitis | 1992 |
Nitric oxide synthesis serves to reduce hepatic damage during acute murine endotoxemia.
Topics: Acute Disease; Animals; Arginine; Bacteremia; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Inflammation; Lipopolysaccharides; Liver Diseases; Liver Function Tests; Mice; Mice, Inbred BALB C; Nitric Oxide; omega-N-Methylarginine | 1992 |
Cardiovascular actions of NG-methyl-L-arginine are abolished in a canine shock model using high-dose endotoxin.
Topics: Animals; Arginine; Blood Pressure; Cardiac Output; Disease Models, Animal; Dogs; Endotoxins; Escherichia coli; Heart; Hypotension; Lipopolysaccharides; Male; Nitric Oxide; omega-N-Methylarginine; Shock; Vascular Resistance; Vasoconstriction | 1992 |
Protective and pathological roles of nitric oxide in endotoxin shock.
Topics: Animals; Arginine; Blood Pressure; Dexamethasone; Disease Models, Animal; Heart Rate; Male; Nitric Oxide; omega-N-Methylarginine; Penicillamine; Rabbits; Regional Blood Flow; S-Nitroso-N-Acetylpenicillamine; Shock, Septic | 1992 |
Role of nitric oxide in renal medullary oxygenation. Studies in isolated and intact rat kidneys.
Topics: Acute Kidney Injury; Animals; Arginine; Disease Models, Animal; Hypoxia; In Vitro Techniques; Kidney Medulla; Nitric Oxide; omega-N-Methylarginine; Oxygen; Perfusion; Rats; Rats, Inbred Strains; Vasodilation | 1991 |