Page last updated: 2024-08-23

oltipraz and Schistosomiasis

oltipraz has been researched along with Schistosomiasis in 18 studies

*Schistosomiasis: Infection with flukes (trematodes) of the genus SCHISTOSOMA. Three species produce the most frequent clinical diseases: SCHISTOSOMA HAEMATOBIUM (endemic in Africa and the Middle East), SCHISTOSOMA MANSONI (in Egypt, northern and southern Africa, some West Indies islands, northern 2/3 of South America), and SCHISTOSOMA JAPONICUM (in Japan, China, the Philippines, Celebes, Thailand, Laos). S. mansoni is often seen in Puerto Ricans living in the United States. [MeSH]

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199016 (88.89)18.7374
1990's1 (5.56)18.2507
2000's0 (0.00)29.6817
2010's1 (5.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrade, CH; Braga, RC; Carpenter, AE; Dantas, RF; de Almeida, AC; Furnham, N; Kamentsky, L; Lima, EF; Melo-Filho, CC; Muratov, E; Neves, BJ; Paveley, R; Rezende-Neto, JM; Senger, MR; Silva-Junior, FP; Valente, WC1
Brücker, G; Danis, M; Duflo, B; Gentilini, M; Meunier, Y; Niel, G; Richard-Lenoble, D1
Charmot, G; Mouchet, F; Rey, JL; Sellin, B; Sellin, E; Simonkovich, E1
Baltes, R; Burchard, GD; Dietrich, M; Kern, P1
Burchard, GD; Dietrich, M; Kern, P1
Abaza, H; El-Kady, A; Wasfy, E1
Ancelle, T; Dupouy-Camet, J; Faurant, C; Heyer, F; Keita, A; Lapierre, J; Tourte-Schaefer, C1
Cavier, R1
Ahmed, MA; Bella, H; Bennett, JL; Mustafa, MD; Rahim, AG; Wasfi, S1
Bueding, E; Dolan, P; Leroy, JP1
Breuil, J; Charmot, G; Coulanges, P; Moyroud, J1
Breuil, J; Coulanges, P; Moyroud, J; Raveloarison, G1
Basset, P; Grégoire, J; Lancastre, F; Lesobre, B; Mafart, Y; Meyniel, D; Piéron, R; Renard, A; Simon, J1
Cerf, P; Coulanges, P; Moyroud, J1
Fleury, MB; Largeron, M; Martens, T1
Archer, S1
Daffalla, AA; Dixon, HG; el Igail, AB; el Tayeb, M; Fenwick, A; Kardaman, MW1
Bennett, JL; Daffalla, AA; el Igail, AB; el Tayeb, M; Fenwick, A; Kardaman, MW1

Reviews

1 review(s) available for oltipraz and Schistosomiasis

ArticleYear
The chemotherapy of schistosomiasis.
    Annual review of pharmacology and toxicology, 1985, Volume: 25

    Topics: Animals; Chemical Phenomena; Chemistry; Diphenylamine; Humans; Hycanthone; Isothiocyanates; Niridazole; Oxamniquine; Praziquantel; Pyrazines; Schistosomiasis; Schistosomicides; Thiocyanates; Thiones; Thiophenes; Trichlorfon

1985

Trials

5 trial(s) available for oltipraz and Schistosomiasis

ArticleYear
Comparative trial of oltipraz versus praziquantel in the treatment of urinary schistosomiasis in the Gabon.
    Tropenmedizin und Parasitologie, 1984, Volume: 35, Issue:2

    Topics: Adolescent; Child; Female; Gabon; Humans; Isoquinolines; Male; Parasite Egg Count; Praziquantel; Pyrazines; Schistosoma; Schistosoma haematobium; Schistosomiasis; Schistosomicides; Species Specificity; Thiones; Thiophenes; Urine; Urologic Diseases

1984
Comparative study of oltipraz versus praziquantel for treatment of schistosomiasis with intestinal manifestation in the Gabon (Schistosoma intercalatum and S. haematobium).
    Tropenmedizin und Parasitologie, 1984, Volume: 35, Issue:2

    Topics: Adolescent; Child; Child, Preschool; Feces; Female; Gabon; Humans; Intestinal Diseases, Parasitic; Isoquinolines; Male; Parasite Egg Count; Praziquantel; Pyrazines; Schistosoma; Schistosoma haematobium; Schistosomiasis; Schistosomicides; Species Specificity; Thiones; Thiophenes

1984
Oltipraz--antischistosomal efficacy in Sudanese infected with Schistosoma mansoni.
    The American journal of tropical medicine and hygiene, 1982, Volume: 31, Issue:4

    Topics: Administration, Oral; Adolescent; Adult; Child; Clinical Trials as Topic; Dose-Response Relationship, Drug; Feces; Humans; Male; Middle Aged; Parasite Egg Count; Pyrazines; Schistosoma mansoni; Schistosomiasis; Schistosomicides; Sudan; Thiones; Thiophenes

1982
Dose-finding trial using Oltipraz to treat schoolchildren infected with Schistosoma mansoni in Gezira, Sudan.
    The Journal of tropical medicine and hygiene, 1985, Volume: 88, Issue:2

    Topics: Abdomen; Administration, Oral; Child; Clinical Trials as Topic; Feces; Fingers; Follow-Up Studies; Humans; Pain; Parasite Egg Count; Pyrazines; Schistosoma mansoni; Schistosomiasis; Schistosomicides; Thiones; Thiophenes; Vision Disorders

1985
Field trials with Oltipraz against Schistosoma mansoni in the Gezira Irrigated Area, Sudan.
    The Journal of tropical medicine and hygiene, 1985, Volume: 88, Issue:2

    Topics: Child; Clinical Trials as Topic; Dose-Response Relationship, Drug; Feces; Humans; Parasite Egg Count; Pyrazines; Schistosoma mansoni; Schistosomiasis; Schistosomicides; Sudan; Thiones; Thiophenes

1985

Other Studies

12 other study(ies) available for oltipraz and Schistosomiasis

ArticleYear
Discovery of New Anti-Schistosomal Hits by Integration of QSAR-Based Virtual Screening and High Content Screening.
    Journal of medicinal chemistry, 2016, Aug-11, Volume: 59, Issue:15

    Topics: Animals; Dose-Response Relationship, Drug; Drug Discovery; Drug Evaluation, Preclinical; Humans; Models, Molecular; Molecular Structure; Quantitative Structure-Activity Relationship; Schistosoma mansoni; Schistosomiasis; Schistosomicides

2016
Assessment of 35972 RP (oltipraz) a new antischistosomal drug against Schistosoma haematobium, Schistosoma mansoni, and Schistosoma intercalatum.
    Acta tropica, 1980, Volume: 37, Issue:3

    Topics: Adolescent; Adult; Child; Drug Administration Schedule; Drug Tolerance; Humans; Pyrazines; Schistosoma haematobium; Schistosoma mansoni; Schistosomiasis; Schistosomicides; Thiones; Thiophenes

1980
[Urinary schistosomiasis. 1st trial of mass treatment in the field (Niger)].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1983, Mar-10, Volume: 59, Issue:10

    Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Female; Humans; Infant; Male; Mass Screening; Niger; Parasite Egg Count; Pyrazines; Schistosomiasis; Schistosomicides; Sex Factors; Thiones; Thiophenes; Urinary Tract Infections

1983
The oral treatment of urinary schistosomiasis in Egyptian patients with 'Oltipraz'.
    Tropical and geographical medicine, 1984, Volume: 36, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Follow-Up Studies; Humans; Parasite Egg Count; Pyrazines; Schistosoma haematobium; Schistosomiasis; Schistosomicides; Thiones; Thiophenes; Urologic Diseases

1984
[Treatment of 700 cases of bilharziasis with the new drugs oxamniquine, oltipraz, praziquantel].
    Bulletin de la Societe de pathologie exotique et de ses filiales, 1983, Volume: 76, Issue:5

    Topics: Adolescent; Adult; Child; Child, Preschool; Humans; Isoquinolines; Middle Aged; Nitroquinolines; Oxamniquine; Paris; Praziquantel; Pyrazines; Schistosoma haematobium; Schistosoma mansoni; Schistosomiasis; Schistosomicides; Thiones; Thiophenes; Togo

1983
[Praziquantel and oltipraz, 2 new polyvalent anthelmintics].
    Bulletin de l'Academie nationale de medecine, 1982, Volume: 166, Issue:1

    Topics: Animals; Anthelmintics; Humans; Isoquinolines; Mice; Praziquantel; Pyrazines; Rats; Schistosomiasis; Schistosomicides; Thiones; Thiophenes

1982
The antischistosomal activity of oltipraz.
    Research communications in chemical pathology and pharmacology, 1982, Volume: 37, Issue:2

    Topics: Animals; Enzyme Induction; Female; Glutathione; Mice; Pyrazines; Schistosoma mansoni; Schistosomiasis; Schistosomicides; Structure-Activity Relationship; Thiones; Thiophenes; Time Factors

1982
[Treatment of bilharziasis in Madagascar. Use of oltipraz in mass campaign against S. mansoni and S. haematobium].
    La Nouvelle presse medicale, 1982, Dec-11, Volume: 11, Issue:50

    Topics: Humans; Madagascar; Pyrazines; Schistosoma haematobium; Schistosoma mansoni; Schistosomiasis; Schistosomicides; Thiones; Thiophenes

1982
[Mass treatment of urinary bilharziasis with a single dose of oltipraz in Madagascar].
    Archives de l'Institut Pasteur de Madagascar, 1982, Volume: 50, Issue:1

    Topics: Adolescent; Child; Child, Preschool; Female; Humans; Madagascar; Male; Pyrazines; Schistosomiasis; Schistosomicides; Thiones; Thiophenes; Urinary Tract Infections

1982
[Oltipraz in one-day treatment of Schistosoma haematobium bilharziasis (pharmacokinetic data, therapeutic effects)].
    La Revue de medecine interne, 1981, Volume: 2, Issue:2

    Topics: Drug Administration Schedule; Female; Humans; Kinetics; Male; Pyrazines; Schistosoma haematobium; Schistosomiasis; Schistosomicides; Thiones; Thiophenes

1981
[Therapy of Schistosoma mansoni bilharziasis with RP. 35972 (Oltipraz). Preliminary results of initial therapy in Madagascar].
    Archives de l'Institut Pasteur de Madagascar, 1981, Volume: 48, Issue:1

    Topics: Adult; Aged; Female; Humans; Madagascar; Male; Middle Aged; Pyrazines; Schistosoma mansoni; Schistosomiasis; Schistosomicides; Thiones; Thiophenes

1981
Toward an understanding of the schistosomicidal effect of 4-methyl-5-(2-pyrazinyl)-1,2-dithiole-3-thione (oltipraz).
    Biochemical pharmacology, 1991, Feb-01, Volume: 41, Issue:3

    Topics: Animals; Disulfides; Glutathione Reductase; Humans; Mice; Models, Chemical; Prodrugs; Pyrazines; Schistosoma; Schistosomiasis; Sulfoxides; Thiones; Thiophenes

1991