Page last updated: 2024-08-23

oltipraz and Neoplasms

oltipraz has been researched along with Neoplasms in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (30.77)18.2507
2000's9 (69.23)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Munday, R; Zhang, Y1
Fishbein, JC; Holland, R; Kensler, TW; Navamal, M; Velayutham, M; Zweier, JL1
Batist, G; Fotouhi-Ardakani, N; Hamilton, D1
Sudakin, DL1
Baumgartner, KJ; Bodreddigari, S; Curphey, TJ; Gange, SJ; Kensler, TW; Li, Y; Roebuck, BD; Sutter, TR; Yan, J1
Chu, H; Cole, SR; Nie, L1
Fishbein, JC; McCraken, J; Muthukumaran, RB; Sostaric, JZ; Velayutham, M; Zweier, JL1
Groopman, JD; Kensler, TW; Roebuck, BD1
Helzlsouer, KJ; Kensler, TW1
Clapper, ML; Szarka, CE1
Curphey, TJ; Groopman, JD; Kensler, TW; Roebuck, BD; Sutter, TR1
Bagnasco, M; Bennicelli, C; Camoirano, A; Cartiglia, C; De Flora, S; Egner, PA; Jacobson, LP; Kensler, TW; Qian, GS; Wang, JB; Zhang, BC; Zhu, YR1
Biswas, S; Das, SK; Gairola, CG1

Reviews

7 review(s) available for oltipraz and Neoplasms

ArticleYear
Dithiolethiones for cancer chemoprevention: where do we stand?
    Molecular cancer therapeutics, 2008, Volume: 7, Issue:11

    Topics: Animals; Anticarcinogenic Agents; Chemoprevention; Humans; Models, Biological; Neoplasms; Pyrazines; Thiones; Thiophenes

2008
The glutathione system in alkylator resistance.
    Cancer treatment and research, 2002, Volume: 112

    Topics: Alkylating Agents; Anticarcinogenic Agents; Buthionine Sulfoximine; Enzyme Inhibitors; Ethacrynic Acid; Glutamate-Cysteine Ligase; Glutathione; Glutathione Synthase; Humans; Neoplasms; Pyrazines; Thiones; Thiophenes

2002
Dietary aflatoxin exposure and chemoprevention of cancer: a clinical review.
    Journal of toxicology. Clinical toxicology, 2003, Volume: 41, Issue:2

    Topics: Aflatoxins; Animals; Anticarcinogenic Agents; Biomarkers; Chlorophyllides; Diet; Humans; Neoplasms; Pyrazines; Reverse Transcriptase Inhibitors; Thiones; Thiophenes

2003
Carcinogen-DNA and protein adducts as intermediate biomarkers for human chemoprotection trials.
    Advances in experimental medicine and biology, 1994, Volume: 354

    Topics: Aflatoxins; Animals; Anticarcinogenic Agents; Biomarkers, Tumor; Carcinogens; DNA; Humans; Liver Neoplasms, Experimental; Neoplasms; Proteins; Pyrazines; Thiones; Thiophenes

1994
Cancer chemoprotection by oltipraz: experimental and clinical considerations.
    Preventive medicine, 1993, Volume: 22, Issue:5

    Topics: Animals; Anticarcinogenic Agents; Clinical Trials as Topic; Drug Screening Assays, Antitumor; Female; Humans; Male; Neoplasms; Neoplasms, Experimental; Pyrazines; Thiones; Thiophenes

1993
Glutathione S-transferases--biomarkers of cancer risk and chemopreventive response.
    Chemico-biological interactions, 1998, Apr-24, Volume: 111-112

    Topics: Animals; Anticarcinogenic Agents; Biomarkers; Brassica; Colitis, Ulcerative; Colorectal Neoplasms; Disease Models, Animal; Enzyme Induction; Gene Expression; Glutathione Transferase; Humans; Inactivation, Metabolic; Mice; Neoplasms; Pyrazines; Risk Factors; Thiones; Thiophenes

1998
Development of cancer chemopreventive agents: oltipraz as a paradigm.
    Chemical research in toxicology, 1999, Volume: 12, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Chemoprevention; Cytochrome P-450 Enzyme System; Drug Approval; Enzyme Induction; Humans; Neoplasms; Pyrazines; Thiones; Thiophenes

1999

Trials

1 trial(s) available for oltipraz and Neoplasms

ArticleYear
Oltipraz chemoprevention trial in Qidong, People's Republic of China: results of urine genotoxicity assays as related to smoking habits.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2001, Volume: 10, Issue:7

    Topics: Administration, Oral; Adult; Biomarkers; Chemoprevention; Escherichia coli; Female; Humans; Male; Mutagenicity Tests; Mutagens; Neoplasms; Pyrazines; Reproducibility of Results; Salmonella typhimurium; Smoking; Thiones; Thiophenes; Urine

2001

Other Studies

5 other study(ies) available for oltipraz and Neoplasms

ArticleYear
Hydrogen peroxide is a second messenger in phase 2 enzyme induction by cancer chemopreventive dithiolethiones.
    Chemical research in toxicology, 2009, Volume: 22, Issue:8

    Topics: Animals; Antineoplastic Agents; Antioxidants; Cyclic N-Oxides; Diglycerides; Enzyme Induction; Hepatocytes; Humans; Hydrogen Peroxide; NAD(P)H Dehydrogenase (Quinone); Neoplasms; Pyrazines; Second Messenger Systems; Thiones; Thiophenes

2009
Evaluation of the cancer chemopreventive potency of dithiolethione analogs of oltipraz.
    Carcinogenesis, 2003, Volume: 24, Issue:12

    Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Antioxidants; Blotting, Western; Carcinogens; DNA; DNA Adducts; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glutathione Transferase; Immunoblotting; Liver; Male; Models, Chemical; Neoplasms; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis; Pyrazines; Rats; Rats, Inbred F344; RNA; RNA, Messenger; Temperature; Thiones; Thiophenes; Time Factors

2003
A general approach for sample size and statistical power calculations assessing of interventions using a mixture model in the presence of detection limits.
    Contemporary clinical trials, 2006, Volume: 27, Issue:5

    Topics: Anticarcinogenic Agents; Clinical Trials as Topic; Computer Simulation; Humans; Models, Statistical; Monte Carlo Method; Neoplasms; Pyrazines; Sample Size; Thiones; Thiophenes

2006
Interactions of the major metabolite of the cancer chemopreventive drug oltipraz with cytochrome c: a novel pathway for cancer chemoprevention.
    Free radical biology & medicine, 2007, Oct-01, Volume: 43, Issue:7

    Topics: Animals; Anticarcinogenic Agents; Antioxidants; Chemoprevention; Cytochromes c; Electron Spin Resonance Spectroscopy; Electron Transport; Heart; Horses; Mass Spectrometry; Mitochondria; Neoplasms; Oxidation-Reduction; Peroxidase; Pyrazines; Reactive Oxygen Species; Spectrophotometry, Ultraviolet; Thiones; Thiophenes

2007
Oltipraz protects the passive smoke induced changes in renal glyoxalase system of rats.
    Molecular and cellular biochemistry, 2002, Volume: 233, Issue:1-2

    Topics: Animals; Anticarcinogenic Agents; Female; Kidney; Lactoylglutathione Lyase; Neoplasms; Pyrazines; Rats; Rats, Sprague-Dawley; Thiolester Hydrolases; Thiones; Thiophenes; Tobacco Smoke Pollution

2002