oltipraz has been researched along with Liver Cirrhosis in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, J; Wang, SY | 1 |
| Kang, KW | 1 |
| Brooks, JS; Brooks, SC; Kim, SG; Lee, MG; Lee, WH | 1 |
| Cho, SH; Choi, JY; Choi, YH; Chon, CY; Han, JY; Jang, JJ; Jang, JW; Kim, SG; Kim, YM; Lee, DH; Lee, MG; Lee, YS; Um, SH; Yu, ES | 1 |
| Cho, SH; Choi, JY; Chon, CY; Han, JY; Jang, JJ; Jang, JW; Kim, SG; Kim, YM; Lee, DH; Lee, YS; Um, SH; Yu, E | 1 |
| Kang, KW; Kim, CW; Kim, SG; Kim, YG | 1 |
| Bae, SK; Kim, JW; Kim, SG; Kim, T; Lee, I; Lee, MG; Lee, SJ | 1 |
| Cho, IJ; Kim, SG; Kim, SH | 1 |
1 review(s) available for oltipraz and Liver Cirrhosis
| Article | Year |
|---|---|
Therapeutic potential of dithiolethiones for hepatic diseases.
Topics: Animals; CCAAT-Enhancer-Binding Protein-beta; Fatty Liver; Glutathione Transferase; Humans; Inactivation, Metabolic; Insulin Resistance; Liver; Liver Cirrhosis; Liver Diseases; MAP Kinase Signaling System; Phosphatidylinositol 3-Kinases; Protein Kinases; Pyrazines; Receptors, Aryl Hydrocarbon; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Thiones; Thiophenes; TOR Serine-Threonine Kinases | 2009 |
2 trial(s) available for oltipraz and Liver Cirrhosis
| Article | Year |
|---|---|
Pharmacokinetics of oltipraz and its major metabolite (RM) in patients with liver fibrosis or cirrhosis: relationship with suppression of circulating TGF-beta1.
Topics: Administration, Oral; Adult; Antiviral Agents; Area Under Curve; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Half-Life; Humans; Liver Cirrhosis; Male; Middle Aged; Pyrazines; Thiones; Thiophenes; Transforming Growth Factor beta1 | 2010 |
Oltipraz therapy in patients with liver fibrosis or cirrhosis: a randomized, double-blind, placebo-controlled phase II trial.
Topics: Adult; Anticarcinogenic Agents; Biomarkers; Biopsy; Collagen; Double-Blind Method; Female; Hepatitis B; Hepatitis C; Humans; Liver; Liver Cirrhosis; Male; Middle Aged; Pyrazines; Thiones; Thiophenes; Transforming Growth Factor beta1 | 2011 |
5 other study(ies) available for oltipraz and Liver Cirrhosis
| Article | Year |
|---|---|
Letter: the efficacy of oltipraz in patients with non-alcoholic fatty liver disease has not been confirmed.
Topics: Fatty Liver; Humans; Liver; Liver Cirrhosis; Non-alcoholic Fatty Liver Disease; Pyrazines; Thiones; Thiophenes | 2017 |
This month in APR.
Topics: Animals; CCAAT-Enhancer-Binding Protein-beta; Cell Proliferation; Cyclin E; Dose-Response Relationship, Drug; Hepatectomy; Hepatocyte Growth Factor; Humans; Liver; Liver Cirrhosis; Liver Regeneration; Phosphatidylinositol 3-Kinases; Pyrazines; Rats; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Thiones; Thiophenes; Time Factors | 2009 |
The anti-fibrogenic effect of a pharmaceutical composition of [5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione] (oltipraz) and dimethyl-4,4'-dimethoxy-5,6,5',6'-dimethylene dioxybiphenyl-2,2'-dicarboxylate (DDB).
Topics: Animals; Drug Combinations; Hydrocarbons, Chlorinated; Liver Cirrhosis; Pharmaceutical Preparations; Pyrazines; Rats; Rats, Sprague-Dawley; Thiones; Thiophenes | 2002 |
Pharmacokinetics and therapeutic effects of oltipraz after consecutive or intermittent oral administration in rats with liver cirrhosis induced by dimethylnitrosamine.
Topics: Administration, Oral; Alkylating Agents; Animals; Area Under Curve; Chromatography, High Pressure Liquid; Creatinine; Dimethylnitrosamine; Half-Life; Hematocrit; Liver; Liver Cirrhosis; Male; Organ Size; Pyrazines; Rats; Rats, Wistar; Schistosomicides; Thiones; Thiophenes | 2006 |
Inhibition of TGFbeta1-mediated PAI-1 induction by oltipraz through selective interruption of Smad 3 activation.
Topics: Active Transport, Cell Nucleus; Animals; Antiviral Agents; Cell Line; Cell Nucleus; Humans; Liver Cirrhosis; Mice; Plasminogen Activator Inhibitor 1; Pyrazines; Rats; Rats, Sprague-Dawley; Receptors, Transforming Growth Factor beta; Signal Transduction; Smad Proteins; Thiones; Thiophenes; Transforming Growth Factor beta1 | 2006 |