oltipraz has been researched along with Experimental Hepatoma in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 10 (90.91) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Egner, PA; Kelloff, GJ; Kensler, TW; Primiano, T; Roebuck, BD; Sutter, TR | 1 |
| Groopman, JD; Kensler, TW; Roebuck, BD | 1 |
| Kensler, TW; MacMillan, DL; Maxuitenko, YY; Roebuck, BD | 1 |
| Bolton, MG; Groopman, JD; Jacobson, LP; Kensler, TW; Maxuitenko, YY; Muñoz, A; Roebuck, BD | 1 |
| Groopman, JD; Kensler, TW; Musser, SM; Scholl, P | 1 |
| Dolan, PM; Egner, PA; Gange, SJ; Groopman, JD; Kensler, TW; Muñoz, A; Roebuck, BD; Rogers, AE | 1 |
| Curphey, TJ; Joyner, HH; Kensler, TW; Libby, AH; MacMillan, DL; Maxuitenko, YY; Roebuck, BD | 1 |
| Curphey, TJ; Eaton, DL; Groopman, JD; Kensler, TW; Roebuck, BD | 1 |
| Groopman, JD; Kensler, TW; Liu, YL; Roebuck, BD; Rogers, AE | 1 |
| DeMatos, P; Egner, PA; Groopman, JD; Kensler, TW; Love-Hunt, A | 1 |
| Dolan, PM; Egner, PA; Groopman, JD; Kensler, TW; Roebuck, BD | 1 |
1 review(s) available for oltipraz and Experimental Hepatoma
| Article | Year |
|---|---|
Carcinogen-DNA and protein adducts as intermediate biomarkers for human chemoprotection trials.
Topics: Aflatoxins; Animals; Anticarcinogenic Agents; Biomarkers, Tumor; Carcinogens; DNA; Humans; Liver Neoplasms, Experimental; Neoplasms; Proteins; Pyrazines; Thiones; Thiophenes | 1994 |
10 other study(ies) available for oltipraz and Experimental Hepatoma
| Article | Year |
|---|---|
Intermittent dosing with oltipraz: relationship between chemoprevention of aflatoxin-induced tumorigenesis and induction of glutathione S-transferases.
Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Carcinogens; Enzyme Induction; Glutathione Transferase; Isoenzymes; Liver; Liver Neoplasms, Experimental; Male; Pyrazines; Rats; Rats, Inbred F344; Thiones; Thiophenes | 1995 |
Evaluation of the post-initiation effects of oltipraz on aflatoxin B1-induced preneoplastic foci in a rat model of hepatic tumorigenesis.
Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Body Weight; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Male; Organ Size; Precancerous Conditions; Pyrazines; Rats; Rats, Inbred F344; Thiones; Thiophenes; Time Factors | 1993 |
Transient intervention with oltipraz protects against aflatoxin-induced hepatic tumorigenesis.
Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; DNA; DNA Adducts; Glutathione Transferase; Liver Neoplasms, Experimental; Male; Pyrazines; Rats; Rats, Inbred F344; Thiones; Thiophenes | 1993 |
Inhibition of aflatoxin Ml excretion in rat urine during dietary intervention with oltipraz.
Topics: Aflatoxin B1; Aflatoxin M1; Animals; Anticarcinogenic Agents; Cytochrome P-450 Enzyme System; Diet; Dose-Response Relationship, Drug; Inactivation, Metabolic; Liver; Liver Neoplasms, Experimental; Male; Pyrazines; Rats; Rats, Inbred F344; Thiones; Thiophenes | 1996 |
Predictive value of molecular dosimetry: individual versus group effects of oltipraz on aflatoxin-albumin adducts and risk of liver cancer.
Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Biomarkers, Tumor; Carcinogens; Cell Transformation, Neoplastic; DNA Adducts; Dose-Response Relationship, Drug; Drug Administration Schedule; Liver Neoplasms, Experimental; Male; Pyrazines; Rats; Rats, Inbred F344; Thiones; Thiophenes | 1997 |
Identification of dithiolethiones with better chemopreventive properties than oltipraz.
Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Enzyme Induction; Liver; Liver Neoplasms, Experimental; Male; Pyrazines; Rats; Rats, Inbred F344; Thiones; Thiophenes | 1998 |
Potent inhibition of aflatoxin-induced hepatic tumorigenesis by the monofunctional enzyme inducer 1,2-dithiole-3-thione.
Topics: Aflatoxin B1; Animals; Antineoplastic Agents; Enzyme Induction; gamma-Glutamyltransferase; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Male; Precancerous Conditions; Pyrazines; Rats; Rats, Inbred F344; Thiones; Thiophenes | 1992 |
Protection against aflatoxin B1-induced hepatocarcinogenesis in F344 rats by 5-(2-pyrazinyl)-4-methyl-1,2-dithiole-3-thione (oltipraz): predictive role for short-term molecular dosimetry.
Topics: Adenoma; Aflatoxin B1; Animals; DNA; gamma-Glutamyltransferase; Growth; Liver; Liver Neoplasms, Experimental; Male; Pyrazines; Rats; Rats, Inbred F344; Survival Analysis; Thiones; Thiophenes | 1991 |
Molecular dosimetry of urinary aflatoxin-N7-guanine and serum aflatoxin-albumin adducts predicts chemoprotection by 1,2-dithiole-3-thione in rats.
Topics: Aflatoxin B1; Animals; Antineoplastic Agents; Biomarkers; DNA; Guanine; Liver Neoplasms, Experimental; Male; Protein Binding; Pyrazines; Rats; Rats, Inbred F344; Serum Albumin; Thiones; Thiophenes | 1992 |
Mechanism of protection against aflatoxin tumorigenicity in rats fed 5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione (oltipraz) and related 1,2-dithiol-3-thiones and 1,2-dithiol-3-ones.
Topics: Aflatoxin B1; Aflatoxins; Animals; Antineoplastic Agents; Cytochrome P-450 Enzyme System; DNA; Enzyme Induction; gamma-Glutamyltransferase; Glutathione Transferase; Heterocyclic Compounds; Liver Neoplasms, Experimental; Male; Precancerous Conditions; Pyrazines; Rats; Rats, Inbred F344; Structure-Activity Relationship; Thiones; Thiophenes | 1987 |