Page last updated: 2024-08-23

oltipraz and Colorectal Cancer

oltipraz has been researched along with Colorectal Cancer in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (50.00)18.2507
2000's3 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Balshem, AM; Brennan, J; Clapper, ML; Engstrom, PF; Frucht, H; Gallo, JM; Goosenberg, EB; Green, F; Halbherr, TC; Hamilton, TC; Litwin, S; O'Dwyer, PJ; Pfeiffer, GR; Szarka, CE; Yao, KS1
Brenner, DE; Krishnan, K1
Clapper, ML; Szarka, CE1
Brenner, DE; Krishnan, K; Ruffin, MT1
Brennan, JM; Gallo, JM; Laub, PB; O'Dwyer, PJ; Szarka, C1
Balshem, AM; Clapper, ML; Engstrom, PF; Frucht, H; Goosenberg, EB; Litwin, S; O'Dwyer, PJ; Pfeiffer, GR; Szarka, CE; Yao, KS1

Reviews

3 review(s) available for oltipraz and Colorectal Cancer

ArticleYear
Chemoprevention of colorectal cancer.
    Gastroenterology clinics of North America, 1996, Volume: 25, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Antioxidants; Calcium; Colorectal Neoplasms; Eflornithine; Ellagic Acid; Humans; Pyrazines; Thiones; Thiophenes

1996
Glutathione S-transferases--biomarkers of cancer risk and chemopreventive response.
    Chemico-biological interactions, 1998, Apr-24, Volume: 111-112

    Topics: Animals; Anticarcinogenic Agents; Biomarkers; Brassica; Colitis, Ulcerative; Colorectal Neoplasms; Disease Models, Animal; Enzyme Induction; Gene Expression; Glutathione Transferase; Humans; Inactivation, Metabolic; Mice; Neoplasms; Pyrazines; Risk Factors; Thiones; Thiophenes

1998
Chemoprevention for colorectal cancer.
    Critical reviews in oncology/hematology, 2000, Volume: 33, Issue:3

    Topics: Adenoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Antioxidants; Apoptosis; Arachidonic Acids; Bile Acids and Salts; Biomarkers; Calcium; Cell Cycle; Cell Transformation, Neoplastic; Clinical Trials as Topic; Colonic Polyps; Colorectal Neoplasms; DNA Methylation; DNA Repair; Eflornithine; Enzyme Inhibitors; Estrogens; Free Radical Scavengers; Genetic Predisposition to Disease; Humans; Mice; Ornithine Decarboxylase Inhibitors; Patient Compliance; Patient Selection; Polyamines; Precancerous Conditions; Pyrazines; Rats; Retinoids; Thiones; Thiophenes; Tumor Cells, Cultured; Vitamins

2000

Trials

3 trial(s) available for oltipraz and Colorectal Cancer

ArticleYear
Modulation of gene expression in subjects at risk for colorectal cancer by the chemopreventive dithiolethione oltipraz.
    The Journal of clinical investigation, 1996, Sep-01, Volume: 98, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anticarcinogenic Agents; Chemoprevention; Colon; Colorectal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Glutamate-Cysteine Ligase; Humans; Inactivation, Metabolic; Intestinal Mucosa; Leukocytes, Mononuclear; Male; Middle Aged; Mutagenesis; NAD(P)H Dehydrogenase (Quinone); Pyrazines; Risk; Thiones; Thiophenes

1996
Pharmacokinetics of the chemopreventive agent oltipraz and of its metabolite M3 in human subjects after a single oral dose.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:12

    Topics: Administration, Oral; Anticarcinogenic Agents; Area Under Curve; Calibration; Chromatography, High Pressure Liquid; Colonic Polyps; Colorectal Neoplasms; Dose-Response Relationship, Drug; Female; Humans; Kinetics; Male; Pyrazines; Risk Factors; Thiones; Thiophenes; Time Factors

2000
Chronic dosing of oltipraz in people at increased risk for colorectal cancer.
    Cancer detection and prevention, 2001, Volume: 25, Issue:4

    Topics: Aged; Aged, 80 and over; Anticarcinogenic Agents; Biomarkers, Tumor; Colorectal Neoplasms; Enzyme Induction; Female; Glutathione; Glutathione Transferase; Humans; Male; Middle Aged; NAD(P)H Dehydrogenase (Quinone); Pyrazines; Thiones; Thiophenes

2001