Compounds > oltipraz
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oltipraz and Colonic Neoplasms

oltipraz has been researched along with Colonic Neoplasms in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (55.56)18.2507
2000's4 (44.44)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Begleiter, A; Bird, RP; Lefas, GM; Maksymiuk, AW; Sivananthan, K1
Begleiter, A; Bird, RP; Curphey, TJ; Sivananthan, K1
Ebert, B; Lampen, A; Seidel, A1
Holt, PR; Liu, T; Mokuolu, AO; Rao, CV; Reddy, BS1
Katiwalla, M; Kelloff, GJ; Rao, CV; Reddy, BS; Rivenson, A1
Reddy, BS1
Clayton, M; Halbherr, T; Myers, CB; O'Dwyer, PJ; Yao, Ks1
Bardiau, C; Guillouzo, A; Lagadic-Gossmann, D; Le Ferrec, E; Le Vee, M; Maheo, K; Massiere, F; Morel, F; Rauch, C1
Nayini, J; Rao, CV; Reddy, BS1

Reviews

1 review(s) available for oltipraz and Colonic Neoplasms

ArticleYear
Chemoprevention of colon cancer by dietary administration of naturally-occurring and related synthetic agents.
    Advances in experimental medicine and biology, 1997, Volume: 400B

    Topics: Allyl Compounds; Anethole Trithione; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Arachidonic Acids; Aspirin; Colon; Colonic Neoplasms; Dinoprostone; Disulfides; Eflornithine; Food, Fortified; Ibuprofen; Intestinal Mucosa; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Piroxicam; Pyrazines; Thiones; Thiophenes

1997

Other Studies

8 other study(ies) available for oltipraz and Colonic Neoplasms

ArticleYear
Inhibition of colon carcinogenesis by post-initiation induction of NQO1 in Sprague-Dawley rats.
    Oncology reports, 2009, Volume: 21, Issue:6

    Topics: Adenoma; Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Enzyme Induction; Glucuronosyltransferase; Glutathione Transferase; Intestinal Mucosa; Male; NAD(P)H Dehydrogenase (Quinone); Neoplasms, Experimental; Precancerous Conditions; Pyrazines; Rats; Rats, Sprague-Dawley; Thiones; Thiophenes; Time Factors

2009
Induction of NAD(P)H quinone: oxidoreductase1 inhibits carcinogen-induced aberrant crypt foci in colons of Sprague-Dawley rats.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2003, Volume: 12, Issue:6

    Topics: Animals; Anticarcinogenic Agents; Carcinogens; Colon; Colonic Neoplasms; Dimethyl Fumarate; Disease Models, Animal; Enzyme Induction; Fumarates; Glucuronosyltransferase; Glutathione Transferase; Inactivation, Metabolic; Intestinal Mucosa; Liver; Male; NAD(P)H Dehydrogenase (Quinone); NADP; Pyrazines; Radiation-Sensitizing Agents; Rats; Rats, Sprague-Dawley; Thiones; Thiophenes

2003
Identification of BCRP as transporter of benzo[a]pyrene conjugates metabolically formed in Caco-2 cells and its induction by Ah-receptor agonists.
    Carcinogenesis, 2005, Volume: 26, Issue:10

    Topics: Adenocarcinoma; Anticarcinogenic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Benzo(a)pyrene; Biological Transport; Cell Line, Tumor; Colonic Neoplasms; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Neoplasm Proteins; Polychlorinated Dibenzodioxins; Pyrazines; Receptors, Aryl Hydrocarbon; Reserpine; RNA, Messenger; Thiones; Thiophenes

2005
Regional chemoprevention of carcinogen-induced tumors in rat colon.
    Gastroenterology, 1995, Volume: 109, Issue:4

    Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Colonic Neoplasms; Eflornithine; Ellagic Acid; Male; Piroxicam; Pyrazines; Rats; Rats, Inbred F344; Thiones; Thiophenes

1995
Chemopreventive effect of oltipraz during different stages of experimental colon carcinogenesis induced by azoxymethane in male F344 rats.
    Cancer research, 1993, Jun-01, Volume: 53, Issue:11

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Azoxymethane; Colonic Neoplasms; Drug Administration Schedule; Drug Screening Assays, Antitumor; Male; Pyrazines; Rats; Rats, Inbred F344; Thiones; Thiophenes

1993
Cellular kinetics of induction by oltipraz and its keto derivative of detoxication enzymes in human colon adenocarcinoma cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1997, Volume: 3, Issue:5

    Topics: Adenocarcinoma; Anticarcinogenic Agents; Cell Cycle; Cell Survival; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; Glutathione Transferase; Humans; Inactivation, Metabolic; Kinetics; NAD(P)H Dehydrogenase (Quinone); Pyrazines; RNA, Messenger; Thiones; Thiophenes; Transcription, Genetic; Tumor Cells, Cultured

1997
Transcriptional induction of CYP1A1 by oltipraz in human Caco-2 cells is aryl hydrocarbon receptor- and calcium-dependent.
    The Journal of biological chemistry, 2002, Jul-05, Volume: 277, Issue:27

    Topics: Animals; Anticarcinogenic Agents; Base Sequence; Caco-2 Cells; Colonic Neoplasms; Cytochrome P-450 CYP1A1; DNA Primers; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Male; Molecular Sequence Data; Promoter Regions, Genetic; Pyrazines; Rats; Rats, Wistar; Receptors, Aryl Hydrocarbon; RNA, Messenger; Thiones; Thiophenes; Transcription, Genetic; Tumor Cells, Cultured

2002
Effect of oltipraz [5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione] on azoxymethane-induced biochemical changes related to early colon carcinogenesis in male F344 rats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1991, Volume: 197, Issue:1

    Topics: Animals; Antineoplastic Agents; Azoxymethane; Body Weight; Colon; Colonic Neoplasms; Cytosol; DNA; Glutathione Transferase; Intestinal Mucosa; Liver; Male; Methylation; Ornithine Decarboxylase; Protein-Tyrosine Kinases; Pyrazines; Rats; Rats, Inbred F344; Reference Values; Thiones; Thiophenes

1991