Page last updated: 2024-08-23

oltipraz and Cancer of Lung

oltipraz has been researched along with Cancer of Lung in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's6 (54.55)18.2507
2000's4 (36.36)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Contreras, ML; Crowell, J; Dimitrov, NV; Madhukar, BV; Meyer-Leece, C1
Becker, F; Bergan, RC; Bhagat, R; Carmella, SG; Crowell, JA; Folz, RJ; Gallot, L; Glaser, EM; Hecht, SS; Herndon, JE; Kelley, MJ; Perloff, M; Santella, RM; Schilder, L; Zhang, YJ1
Gao, P; Sharma, S; Steele, VE1
Kresty, LA; Morse, MA; Stoner, GD; Zu, H1
Li, ZQ1
Groopman, JD; Kensler, TW1
Bagnasco, M; Bennicelli, C; Camoirano, A; De Flora, S; Kensler, TW; Qian, GS; van Zandwijk, N; Wigbout, G; Zhu, YR1
Bennett, JL; Bennink, M; Crowell, J; Dimitrov, NV; Gardiner, J; Hawk, E; Leece, CM; Nashawaty, M; Seymour, E; Tompkins, ER1
Bai, H; Chen, F; Hu, G; Luo, X; Wei, H; Zhu, M1
Bouchard, L; Castonguay, A; Nicole, P; Pepin, P1
Bueding, E; Wattenberg, LW1

Reviews

1 review(s) available for oltipraz and Cancer of Lung

ArticleYear
Carcinogen-DNA and protein adducts: biomarkers for cohort selection and modifiable endpoints in chemoprevention trials.
    Journal of cellular biochemistry. Supplement, 1996, Volume: 25

    Topics: Aflatoxin B1; Aflatoxins; Aged; Anticarcinogenic Agents; Biomarkers, Tumor; Carcinogens; Clinical Trials as Topic; Cohort Studies; DNA Adducts; Guanine; Hepatitis B; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Proteins; Pyrazines; Risk Factors; Thiones; Thiophenes

1996

Trials

2 trial(s) available for oltipraz and Cancer of Lung

ArticleYear
Safety and efficacy of weekly oral oltipraz in chronic smokers.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2005, Volume: 14, Issue:4

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Administration, Oral; Adult; Aged; Anticarcinogenic Agents; Bronchoalveolar Lavage Fluid; Drug Administration Schedule; Female; Humans; Lung Neoplasms; Male; Middle Aged; Polycyclic Aromatic Hydrocarbons; Pyrazines; Smoking; Thiones; Thiophenes

2005
Oltipraz concentrations in plasma, buccal mucosa cells, and lipids: pharmacological studies.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2001, Volume: 10, Issue:3

    Topics: Administration, Oral; Adult; Anticarcinogenic Agents; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Lipid Metabolism; Lung Neoplasms; Male; Middle Aged; Mouth Mucosa; Probability; Pyrazines; Risk Assessment; Sensitivity and Specificity; Smoking; Statistics, Nonparametric; Thiones; Thiophenes; Tissue Distribution

2001

Other Studies

8 other study(ies) available for oltipraz and Cancer of Lung

ArticleYear
Inhibition of mitogen-activated protein kinase activity of human lymphocytes after oral administration of Oltipraz.
    Molecular cancer therapeutics, 2002, Volume: 1, Issue:12

    Topics: Administration, Oral; Adult; Anticarcinogenic Agents; Blotting, Western; Enzyme Inhibitors; Female; Humans; Lung Neoplasms; Lymphocytes; Male; MAP Kinase Signaling System; Middle Aged; Phosphorylation; Pyrazines; Signal Transduction; Thiones; Thiophenes

2002
The chemopreventive efficacy of inhaled oltipraz particulates in the B[a]P-induced A/J mouse lung adenoma model.
    Carcinogenesis, 2006, Volume: 27, Issue:8

    Topics: Adenoma; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Female; Inhalation; Lung Neoplasms; Mice; Mice, Inbred A; Pyrazines; Thiones; Thiophenes

2006
Failure of dietary oltipraz to inhibit benzo[a]pyrene-induced lung tumorigenesis in strain a mice.
    Cancer letters, 1995, May-04, Volume: 91, Issue:1

    Topics: Adenoma; Animals; Anticarcinogenic Agents; Benzopyrenes; Diet; Female; Glutathione Transferase; Lung; Lung Neoplasms; Mice; Mice, Inbred A; Pyrazines; Thiones; Thiophenes

1995
[Study on initiation of human lung carcinogenesis].
    Sheng li ke xue jin zhan [Progress in physiology], 1993, Volume: 24, Issue:4

    Topics: Anticarcinogenic Agents; Cell Transformation, Neoplastic; Cells, Cultured; Diethylnitrosamine; Humans; Lung Neoplasms; Pyrazines; Smoking; Thiones; Thiophenes

1993
Smokers and urinary genotoxins: implications for selection of cohorts and modulation of endpoints in chemoprevention trials.
    Journal of cellular biochemistry. Supplement, 1996, Volume: 25

    Topics: Acetylcysteine; Adult; Anticarcinogenic Agents; Biomarkers, Tumor; Chemoprevention; China; Clinical Trials, Phase II as Topic; Cohort Studies; DNA Repair; Female; Humans; Lung Neoplasms; Male; Middle Aged; Mutagenicity Tests; Mutagens; Netherlands; Pyrazines; Research Design; Smoking; Thiones; Thiophenes

1996
[Studies on apoptosis of human lung adenocarcinoma cells induced by oltipraz].
    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 1999, Volume: 33, Issue:3

    Topics: Adenocarcinoma; Anticarcinogenic Agents; Apoptosis; Dose-Response Relationship, Drug; Humans; Lung Neoplasms; Mitosis; Pyrazines; Thiones; Thiophenes; Tumor Cells, Cultured

1999
Effects of sulindac and oltipraz on the tumorigenicity of 4-(methylnitrosamino)1-(3-pyridyl)-1-butanone in A/J mouse lung.
    Carcinogenesis, 1992, Volume: 13, Issue:3

    Topics: Adenoma; Animals; Carcinogens; Drug Screening Assays, Antitumor; Female; Intestinal Absorption; Lung; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Nitrosamines; Oxidation-Reduction; Pyrazines; Schistosomicides; Sulindac; Thiones; Thiophenes

1992
Inhibitory effects of 5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione (Oltipraz) on carcinogenesis induced by benzo[a]pyrene, diethylnitrosamine and uracil mustard.
    Carcinogenesis, 1986, Volume: 7, Issue:8

    Topics: Animals; Benzo(a)pyrene; Diethylnitrosamine; Female; Lung Neoplasms; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Pyrazines; Stomach Neoplasms; Thiones; Thiophenes; Uracil Mustard

1986