oltipraz has been researched along with Angiogenesis, Pathologic in 3 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (66.67) | 29.6817 |
2010's | 1 (33.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Brooks, SC; Choi, JH; Kim, SG; Kim, YW; Lee, MO; Lee, WH | 1 |
Kang, SG; Kim, SG; Lee, WH; Lee, YH; Lee, YS | 1 |
Angeles, T; Clapper, ML; Robinson, C; Ruggeri, BA; Wilkinson, J | 1 |
3 other study(ies) available for oltipraz and Angiogenesis, Pathologic
Article | Year |
---|---|
Oltipraz and dithiolethione congeners inhibit hypoxia-inducible factor-1alpha activity through p70 ribosomal S6 kinase-1 inhibition and H2O2-scavenging effect.
Topics: Adenylate Kinase; Animals; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Free Radical Scavengers; Gene Expression Regulation, Neoplastic; Humans; Hydrogen Peroxide; Hypoxia-Inducible Factor 1, alpha Subunit; Insulin; Mice; Neovascularization, Pathologic; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Protein Stability; Pyrazines; Ribosomal Protein S6 Kinases, 70-kDa; Thiones; Thiophenes; Transcription, Genetic; Ubiquitin | 2009 |
Hypoxia-inducible factor-1α inhibition by a pyrrolopyrazine metabolite of oltipraz as a consequence of microRNAs 199a-5p and 20a induction.
Topics: Cell Hypoxia; Cell Line, Tumor; Cell Movement; Cobalt; HT29 Cells; Humans; Hydrogen Peroxide; Hypoxia-Inducible Factor 1, alpha Subunit; Insulin; MicroRNAs; Neoplasm Invasiveness; Neovascularization, Pathologic; Pyrazines; Pyridazines; Pyrroles; Thiones; Thiophenes | 2012 |
The chemopreventive agent oltipraz possesses potent antiangiogenic activity in vitro, ex vivo, and in vivo and inhibits tumor xenograft growth.
Topics: Angiogenesis Inhibitors; Animals; Anticarcinogenic Agents; Cell Division; Dose-Response Relationship, Drug; Endothelium, Vascular; Hemangiosarcoma; Humans; Insulin-Like Growth Factor I; Liver; Male; Mice; Mice, Nude; Neovascularization, Pathologic; Oligonucleotide Array Sequence Analysis; Pyrazines; Rats; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 4; Receptors, Fibroblast Growth Factor; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; Ribonuclease, Pancreatic; Thiones; Thiophenes; Transplantation, Heterologous; Tumor Cells, Cultured | 2002 |