olprinone has been researched along with Reperfusion Injury in 8 studies
olprinone: RN refers to HCl; structure given in first source
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our results indicated that olprinone up-regulated cAMP in injured ileum tissue, and decreased the ileum tissue damage after 1 h of reperfusion in SAO shock mice." | 7.76 | Olprinone attenuates the development of ischemia/reperfusion injury of the gut. ( Caminiti, R; Crisafulli, C; Cuzzocrea, S; Galuppo, M; Mazzon, E; Paterniti, I, 2010) |
| "Olprinone treatment showed marked reduction in infarct size compared with control rats." | 5.37 | Neuroprotective effects of olprinone after cerebral ischemia/reperfusion injury in rats. ( Cuzzocrea, S; Esposito, E; Genovese, T; Mazzon, E; Paterniti, I, 2011) |
| "Olprinone is a newly developed selective phosphodiesterase III inhibitor, which has been reported to ameliorate renal I/R injury in rats." | 5.36 | Effect of olprinone, a phosphodiesterase III inhibitor, on hepatic ischemia-reperfusion injury in rats. ( Hua, J; Inada, E; Kawahara, T; Kugimiya, T; Kumakura, S; Nagaoka, I; Yamaguchi, K, 2010) |
| "Our results indicated that olprinone up-regulated cAMP in injured ileum tissue, and decreased the ileum tissue damage after 1 h of reperfusion in SAO shock mice." | 3.76 | Olprinone attenuates the development of ischemia/reperfusion injury of the gut. ( Caminiti, R; Crisafulli, C; Cuzzocrea, S; Galuppo, M; Mazzon, E; Paterniti, I, 2010) |
| "Olprinone treatment showed marked reduction in infarct size compared with control rats." | 1.37 | Neuroprotective effects of olprinone after cerebral ischemia/reperfusion injury in rats. ( Cuzzocrea, S; Esposito, E; Genovese, T; Mazzon, E; Paterniti, I, 2011) |
| "Olprinone is a newly developed selective phosphodiesterase III inhibitor, which has been reported to ameliorate renal I/R injury in rats." | 1.36 | Effect of olprinone, a phosphodiesterase III inhibitor, on hepatic ischemia-reperfusion injury in rats. ( Hua, J; Inada, E; Kawahara, T; Kugimiya, T; Kumakura, S; Nagaoka, I; Yamaguchi, K, 2010) |
| "Olprinone inhibited the increase in the IL-8 levels resulting from the incubation of HK-2 with TNF-alpha." | 1.34 | Effects of olprinone, a phosphodiesterase III inhibitor, on ischemic acute renal failure. ( Anas, C; Maruyama, S; Matsuo, S; Ono, Y; Ozaki, T; Yamamoto, T; Zu Gotoh, M, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bejaoui, M | 1 |
| Zaouali, MA | 1 |
| Sakly, R | 1 |
| Ben Abdennebi, H | 1 |
| Yamaguchi, K | 1 |
| Kawahara, T | 1 |
| Kumakura, S | 1 |
| Hua, J | 1 |
| Kugimiya, T | 1 |
| Nagaoka, I | 1 |
| Inada, E | 1 |
| Kobayashi, T | 1 |
| Crisafulli, C | 1 |
| Mazzon, E | 2 |
| Galuppo, M | 1 |
| Paterniti, I | 2 |
| Caminiti, R | 1 |
| Cuzzocrea, S | 2 |
| Genovese, T | 1 |
| Esposito, E | 1 |
| Mizutani, A | 1 |
| Murakami, K | 1 |
| Okajima, K | 1 |
| Kira, S | 1 |
| Mizutani, S | 1 |
| Kudo, K | 1 |
| Takatani, J | 1 |
| Goto, K | 1 |
| Hattori, S | 1 |
| Noguchi, T | 1 |
| Zhang, Y | 1 |
| Ma, Q | 1 |
| Anas, C | 1 |
| Ozaki, T | 1 |
| Maruyama, S | 1 |
| Yamamoto, T | 1 |
| Zu Gotoh, M | 1 |
| Ono, Y | 1 |
| Matsuo, S | 1 |
8 other studies available for olprinone and Reperfusion Injury
| Article | Year |
|---|---|
Olprinone protects the liver from ischemia-reperfusion injury through oxidative stress prevention and protein kinase Akt activation.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Catalase; Cytoprotection; Enzyme Activat | 2018 |
Effect of olprinone, a phosphodiesterase III inhibitor, on hepatic ischemia-reperfusion injury in rats.
Topics: Animals; Cyclic AMP; Imidazoles; Intercellular Adhesion Molecule-1; JNK Mitogen-Activated Protein Ki | 2010 |
A phosphodiesterase III inhibitor protects rat liver from sinusoidal obstruction syndrome through heme oxygenase-1 induction.
Topics: Amrinone; Animals; Heme Oxygenase-1; Hepatectomy; Hepatic Veno-Occlusive Disease; Imidazoles; Phosph | 2010 |
Olprinone attenuates the development of ischemia/reperfusion injury of the gut.
Topics: Animals; Arterial Occlusive Diseases; Blotting, Western; Cardiotonic Agents; Ileum; Imidazoles; Male | 2010 |
Neuroprotective effects of olprinone after cerebral ischemia/reperfusion injury in rats.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Behavior, Animal; Brain; Brain Ischemia; Cerebral Co | 2011 |
Olprinone reduces ischemia/reperfusion-induced acute renal injury in rats through enhancement of cAMP.
Topics: Animals; Blood Urea Nitrogen; Cardiotonic Agents; Creatinine; Cyclic AMP; Hemodynamics; Imidazoles; | 2005 |
The enhancement of cellular cAMP with olprinone protects autotransplanted rat kidney against cold ischemia-reperfusion injury.
Topics: Animals; Cyclic AMP; Imidazoles; Kidney Transplantation; Kidney Tubules; Male; Models, Animal; Phosp | 2006 |
Effects of olprinone, a phosphodiesterase III inhibitor, on ischemic acute renal failure.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Acute Kidney Injury; Animals; Blood Flow Velocity; Blood Urea N | 2007 |