olprinone has been researched along with Liver Failure in 3 studies
olprinone: RN refers to HCl; structure given in first source
Liver Failure: Severe inability of the LIVER to perform its normal metabolic functions, as evidenced by severe JAUNDICE and abnormal serum levels of AMMONIA; BILIRUBIN; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; LACTATE DEHYDROGENASES; and albumin/globulin ratio. (Blakiston's Gould Medical Dictionary, 4th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The rate of post-hepatectomy liver failure frequency tended to be lower in the olprinone group." | 5.24 | Phase I clinical trial of olprinone in liver surgery. ( Fuji, H; Hatano, E; Iguchi, K; Ikeno, Y; Ishii, H; Kobayashi, M; Seo, S; Tanaka, S; Taura, K; Uemoto, S; Ueno, K; Yamanaka, K; Yasuchika, K; Yoh, T, 2017) |
| "Olprinone treatment was demonstrated to have therapeutic potential to overcome SFSS." | 1.39 | Effect of olprinone on liver microstructure in rat partial liver transplantation. ( Hatano, E; Iguchi, K; Koyama, N; Nagata, H; Nakamura, K; Narita, M; Sato, M; Takemoto, K; Tanabe, K; Taura, K; Toriguchi, K; Uemoto, S; Yamamoto, G; Yamanaka, K, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fuji, H | 1 |
| Hatano, E | 3 |
| Iguchi, K | 2 |
| Yamanaka, K | 3 |
| Yoh, T | 1 |
| Ikeno, Y | 1 |
| Seo, S | 1 |
| Taura, K | 3 |
| Yasuchika, K | 1 |
| Tanaka, S | 1 |
| Ishii, H | 1 |
| Kobayashi, M | 1 |
| Ueno, K | 1 |
| Uemoto, S | 3 |
| Narita, M | 2 |
| Kitamura, K | 1 |
| Yanagida, A | 1 |
| Asechi, H | 1 |
| Nagata, H | 2 |
| Nitta, T | 1 |
| Yamamoto, G | 1 |
| Sato, M | 1 |
| Toriguchi, K | 1 |
| Tanabe, K | 1 |
| Takemoto, K | 1 |
| Nakamura, K | 1 |
| Koyama, N | 1 |
1 trial available for olprinone and Liver Failure
| Article | Year |
|---|---|
Phase I clinical trial of olprinone in liver surgery.
Topics: Aged; Carcinoma, Hepatocellular; Cohort Studies; Female; Hepatectomy; Humans; Imidazoles; Incidence; | 2017 |
2 other studies available for olprinone and Liver Failure
| Article | Year |
|---|---|
Olprinone attenuates excessive shear stress through up-regulation of endothelial nitric oxide synthase in a rat excessive hepatectomy model.
Topics: Animals; Apoptosis; Disease Models, Animal; Endothelial Cells; Enzyme Inhibitors; Hepatectomy; Hepat | 2011 |
Effect of olprinone on liver microstructure in rat partial liver transplantation.
Topics: Animals; Drug Evaluation, Preclinical; Endothelial Cells; Hepatocytes; Imidazoles; Liver; Liver Fail | 2013 |