Page last updated: 2024-11-01

olprinone and Innate Inflammatory Response

olprinone has been researched along with Innate Inflammatory Response in 5 studies

olprinone: RN refers to HCl; structure given in first source

Research Excerpts

ExcerptRelevanceReference
"Effects of the selective phosphodiesterase 3 (PDE3) inhibitor olprinone and the selective PDE4 inhibitor SB207499 were investigated on antigen-induced increase of cough reflex sensitivity and normal cough response to capsaicin in guinea pigs."3.74Selective inhibitors for phosphodiesterase 3 and 4 in antigen-induced increase of cough reflex sensitivity in guinea pigs. ( Fujimura, M; Liu, Q, 2007)
"Treatment with olprinone reduced the numbers of polymorphonuclears in the BAL fluid, decreased the formation of most oxidation markers in the lungs, reduced lung edema and prevented a decrease in TAS in the lung homogenate compared to non-treated animals."1.38Selective phosphodiesterase 3 inhibitor olprinone attenuates meconium-induced oxidative lung injury. ( Calkovska, A; Drgova, A; Mokra, D; Pullmann, R, 2012)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Di Paola, R1
Mazzon, E1
Paterniti, I1
Impellizzeri, D1
Bramanti, P1
Cuzzocrea, S1
Mokra, D1
Drgova, A1
Pullmann, R1
Calkovska, A1
Mizutani, A1
Murakami, K1
Okajima, K1
Kira, S1
Mizutani, S1
Kudo, K1
Takatani, J1
Goto, K1
Hattori, S1
Noguchi, T1
Fujimura, M1
Liu, Q1
Yamaura, K1
Akiyoshi, K1
Irita, K1
Taniyama, T1
Takahashi, S1

Trials

1 trial available for olprinone and Innate Inflammatory Response

ArticleYear
Effects of olprinone, a new phosphodiesterase inhibitor, on gastric intramucosal acidosis and systemic inflammatory responses following hypothermic cardiopulmonary bypass.
    Acta anaesthesiologica Scandinavica, 2001, Volume: 45, Issue:4

    Topics: Acidosis; Aged; Cardiopulmonary Bypass; Female; Gastric Acidity Determination; Gastric Mucosa; Hemod

2001

Other Studies

4 other studies available for olprinone and Innate Inflammatory Response

ArticleYear
Olprinone, a PDE3 inhibitor, modulates the inflammation associated with myocardial ischemia-reperfusion injury in rats.
    European journal of pharmacology, 2011, Jan-15, Volume: 650, Issue:2-3

    Topics: Animals; Apoptosis; Imidazoles; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-1beta;

2011
Selective phosphodiesterase 3 inhibitor olprinone attenuates meconium-induced oxidative lung injury.
    Pulmonary pharmacology & therapeutics, 2012, Volume: 25, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Bronchoalveolar Lavage Fluid; Disease Models, Anima

2012
Olprinone reduces ischemia/reperfusion-induced acute renal injury in rats through enhancement of cAMP.
    Shock (Augusta, Ga.), 2005, Volume: 24, Issue:3

    Topics: Animals; Blood Urea Nitrogen; Cardiotonic Agents; Creatinine; Cyclic AMP; Hemodynamics; Imidazoles;

2005
Selective inhibitors for phosphodiesterase 3 and 4 in antigen-induced increase of cough reflex sensitivity in guinea pigs.
    Pulmonary pharmacology & therapeutics, 2007, Volume: 20, Issue:5

    Topics: Allergens; Animals; Antigens; Bronchoalveolar Lavage; Capsaicin; Cough; Cyclohexanecarboxylic Acids;

2007