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olprinone and Endotoxemia

olprinone has been researched along with Endotoxemia in 2 studies

olprinone: RN refers to HCl; structure given in first source

Endotoxemia: A condition characterized by the presence of ENDOTOXINS in the blood. On lysis, the outer cell wall of gram-negative bacteria enters the systemic circulation and initiates a pathophysiologic cascade of pro-inflammatory mediators.

Research Excerpts

ExcerptRelevanceReference
"This study was performed in order to assess the effects of olprinone, a phosphodiesterase III inhibitor, on hepatic oxygen delivery (DO2H), oxygen consumption (VO2H), and mitochondrial oxidation in the liver of a porcine endotoxemia model."7.73Effects of olprinone on hepatosplanchnic circulation and mitochondrial oxidation in a porcine model of endotoxemia. ( Hashiguchi, T; Isowaki, S; Kakihana, Y; Kaminosono, T; Kanmura, Y; Kawamae, H; Kuniyoshi, T; Nagata, E; Okayama, N; Tahara, M; Tobo, K, 2005)
" The administration of olprinone (phosphodiesterase III inhibitor) improves the liver blood flow circulation in a porcine model of endotoxemia."7.71The effects of olprinone (a phosphodiesterase III inhibitor) on hepatic vascular bed in a porcine model of endotoxemia. ( Isowaki, S; Kakihana, Y; Kanmura, Y; Nagata, E; Tobo, K, 2001)
"This study was performed in order to assess the effects of olprinone, a phosphodiesterase III inhibitor, on hepatic oxygen delivery (DO2H), oxygen consumption (VO2H), and mitochondrial oxidation in the liver of a porcine endotoxemia model."3.73Effects of olprinone on hepatosplanchnic circulation and mitochondrial oxidation in a porcine model of endotoxemia. ( Hashiguchi, T; Isowaki, S; Kakihana, Y; Kaminosono, T; Kanmura, Y; Kawamae, H; Kuniyoshi, T; Nagata, E; Okayama, N; Tahara, M; Tobo, K, 2005)
" The administration of olprinone (phosphodiesterase III inhibitor) improves the liver blood flow circulation in a porcine model of endotoxemia."3.71The effects of olprinone (a phosphodiesterase III inhibitor) on hepatic vascular bed in a porcine model of endotoxemia. ( Isowaki, S; Kakihana, Y; Kanmura, Y; Nagata, E; Tobo, K, 2001)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kuniyoshi, T1
Kakihana, Y2
Isowaki, S2
Nagata, E2
Tobo, K2
Kaminosono, T1
Hashiguchi, T1
Tahara, M1
Kawamae, H1
Okayama, N1
Kanmura, Y2

Other Studies

2 other studies available for olprinone and Endotoxemia

ArticleYear
Effects of olprinone on hepatosplanchnic circulation and mitochondrial oxidation in a porcine model of endotoxemia.
    Journal of anesthesia, 2005, Volume: 19, Issue:4

    Topics: Animals; Disease Models, Animal; Electron Transport Complex IV; Endotoxemia; Endotoxins; Hemoglobins

2005
The effects of olprinone (a phosphodiesterase III inhibitor) on hepatic vascular bed in a porcine model of endotoxemia.
    Anesthesia and analgesia, 2001, Volume: 92, Issue:3

    Topics: Animals; Disease Models, Animal; Endotoxemia; Imidazoles; Liver Circulation; Oxygen; Phosphodiestera

2001