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olpadronic acid and Bone Loss, Osteoclastic

olpadronic acid has been researched along with Bone Loss, Osteoclastic in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19902 (10.53)18.7374
1990's9 (47.37)18.2507
2000's8 (42.11)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bachmann, R; Bisping, M; Born, AR; Cortesi, R; Glatt, M; Green, JR; Guiglia, G; Jaeggi, KA; Jeker, H; Klein, R; Müller, K; Ramseier, U; Schmid, J; Schreiber, G; Seltenmeyer, Y; Widler, L1
Engelbert, R; Jansen, M; Kok, D; Pruijs, H; Sakkers, R; Schweitzer, D; Uiterwaal, C; van Dongen, A; Verbout, A1
De Grandi, MC; Friedman, S; Gamba, CA; Mandalunis, P; Somoza, J; Tomat, A; Zeni, S1
Goya, JA; Mandalunis, PM; Paez, HA1
Kurth, KH; Löwik, C; Papapoulos, S; Schamhart, D; Theuns, H; Weissglas, M1
Bloys, H; Löwik, C; Oostendorp-van de Ruit, M; Papapoulos, S; van Beek, E; van de Bent, C; van der Wee-Pals, L1
Bijvoet, OL; Papapoulos, SE; Schweitzer, DH; Vermeij, P; Zwinderman, AH1
Löwik, C; Papapoulos, S; Que, I; Van Beek, E1
Gomez-Acotto, C; Mautalen, C; Zeni, S1
Brown, RJ; Löwik, CW; Papapoulos, SE; van Beek, E; Watts, DJ1
Hamdy, NA; Lycklama à Nijeholt, AA; Papapoulos, SE; Pelger, RC; Zwinderman, AH1
Cohen, L; Löwik, C; Papapoulos, S; Pieterman, E; van Beek, E1
Berenson, J; Hortobagyi, G; Lipton, A; Major, PP1
Löwik, CW; Papapoulos, SE; Van Beek, ER1
Gomez, AC; Gregorio, S; Mautalen, C; Somoza, J; Zeni, SN1
Alblas, MJ; Bijvoet, OL; de Groot, H; Löwik, CW; Papapoulos, SE; van der Pluijm, G; van der Wee-Pals, LJ1
Hoekman, K; Papapoulos, SE; Tjandra, YI1
Bijvoet, OL; Hoekman, K; Löwik, CW; Papapoulos, SE; Vermeij, P1
Bijvoet, OL; Löwik, CW; van der Pluijm, G; van der Wee-Pals, LJ; van Treslong-De Groot, HB1

Reviews

1 review(s) available for olpadronic acid and Bone Loss, Osteoclastic

ArticleYear
Oral bisphosphonates: A review of clinical use in patients with bone metastases.
    Cancer, 2000, Jan-01, Volume: 88, Issue:1

    Topics: Alendronate; Biological Availability; Bone Density; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Calcium; Clodronic Acid; Diphosphonates; Double-Blind Method; Etidronic Acid; Humans; Ibandronic Acid; Imidazoles; Male; Multiple Myeloma; Pamidronate; Prostatic Neoplasms; Pyridines; Randomized Controlled Trials as Topic; Risedronic Acid; Zoledronic Acid

2000

Trials

2 trial(s) available for olpadronic acid and Bone Loss, Osteoclastic

ArticleYear
Skeletal effects and functional outcome with olpadronate in children with osteogenesis imperfecta: a 2-year randomised placebo-controlled study.
    Lancet (London, England), 2004, May-01, Volume: 363, Issue:9419

    Topics: Activities of Daily Living; Administration, Oral; Adolescent; Bone Density; Bone Resorption; Child; Child, Preschool; Diphosphonates; Double-Blind Method; Female; Fractures, Spontaneous; Humans; Locomotion; Male; Osteogenesis Imperfecta

2004
Effects of the bisphosphonate olpadronate in patients with carcinoma of the prostate metastatic to the skeleton.
    Bone, 1998, Volume: 22, Issue:4

    Topics: Administration, Oral; Aged; Aged, 80 and over; Alkaline Phosphatase; Antineoplastic Agents; Bone Neoplasms; Bone Resorption; Calcium; Diphosphonates; Follow-Up Studies; Humans; Hydroxyproline; Injections, Intravenous; Male; Middle Aged; Neoplasm Metastasis; Osteoblasts; Pain; Prostatic Neoplasms

1998

Other Studies

16 other study(ies) available for olpadronic acid and Bone Loss, Osteoclastic

ArticleYear
Highly potent geminal bisphosphonates. From pamidronate disodium (Aredia) to zoledronic acid (Zometa).
    Journal of medicinal chemistry, 2002, Aug-15, Volume: 45, Issue:17

    Topics: Animals; Bone Resorption; Calcitriol; Diphosphonates; Hypercalcemia; Imidazoles; In Vitro Techniques; Kidney; Mice; Pamidronate; Parathyroidectomy; Rats; Skull; Structure-Activity Relationship; Thyroidectomy; Zoledronic Acid

2002
Changes in bone volume and bone resorption by olpadronate treatment in an experimental model of uremic bone disease.
    Journal of musculoskeletal & neuronal interactions, 2005, Volume: 5, Issue:2

    Topics: Alkaline Phosphatase; Amino Acids; Animals; Bone and Bones; Bone Density; Bone Diseases, Metabolic; Bone Resorption; Calcium; Creatinine; Diphosphonates; Disease Models, Animal; Kidney; Male; Phosphorus; Rats; Uremia

2005
Effect of topical administration of monosodium olpadronate on experimental periodontitis in rats.
    Journal of periodontology, 2006, Volume: 77, Issue:1

    Topics: Administration, Topical; Alveolar Bone Loss; Alveolar Process; Animals; Bone Density Conservation Agents; Bone Resorption; Cell Nucleus; Cell Polarity; Cell Shape; Diphosphonates; Furcation Defects; Male; Mandible; Osteoblasts; Osteoclasts; Periodontal Ligament; Periodontitis; Rats; Rats, Wistar

2006
Bone resorption and renal calcium reabsorption in renal cell carcinoma-bearing mice: the effects of bisphosphonate.
    BJU international, 2007, Volume: 99, Issue:6

    Topics: Animals; Bone Density Conservation Agents; Bone Resorption; Calcium; Carcinoma, Renal Cell; Diphosphonates; Humans; Hypercalcemia; Kidney Neoplasms; Mice; Mice, Nude

2007
Effects of experimental conditions on the release of 45calcium from prelabeled fetal mouse long bones.
    Bone, 1995, Volume: 17, Issue:1

    Topics: Acid Phosphatase; Animals; Bone Marrow Cells; Bone Resorption; Calcium; Calcium Radioisotopes; Cells, Cultured; Culture Techniques; Diphosphonates; Dose-Response Relationship, Drug; Growth Inhibitors; Interleukin-6; Isoenzymes; Leukemia Inhibitory Factor; Lymphokines; Metacarpus; Metatarsal Bones; Mice; Osteoclasts; Parathyroid Hormone; Radius; Stromal Cells; Tartrate-Resistant Acid Phosphatase; Ulna

1995
Improved treatment of Paget's disease with dimethylaminohydroxypropylidene bisphosphonate.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1993, Volume: 8, Issue:2

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Bone Resorption; Diphosphonates; Drug Administration Schedule; Female; Humans; Injections, Intravenous; Male; Middle Aged; Osteitis Deformans; Pamidronate; Remission Induction

1993
Dissociation of binding and antiresorptive properties of hydroxybisphosphonates by substitution of the hydroxyl with an amino group.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1996, Volume: 11, Issue:10

    Topics: Amines; Analysis of Variance; Animals; Binding Sites; Bone Matrix; Bone Resorption; Calcium Oxalate; Crystallization; Diphosphonates; Etidronic Acid; Female; Mice; Pamidronate; Pregnancy; Structure-Activity Relationship

1996
The effect of olpadronate in ovariectomized thyroxine-treated rats.
    Bone, 1997, Volume: 21, Issue:4

    Topics: Alkaline Phosphatase; Animals; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Creatinine; Diphosphonates; Estrogens; Female; Humans; Hydroxyproline; Hyperthyroidism; Osteoporosis, Postmenopausal; Ovariectomy; Rats; Rats, Sprague-Dawley; Thyroxine

1997
Differential effects of aminosubstituted analogs of hydroxy bisphosphonates on the growth of Dictyostelium discoideum.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1998, Volume: 13, Issue:2

    Topics: Amines; Animals; Bone Density; Bone Resorption; Dictyostelium; Diphosphonates; Dose-Response Relationship, Drug; Etidronic Acid; Female; Hindlimb; Mice; Pamidronate; Structure-Activity Relationship

1998
Nitrogen-containing bisphosphonates inhibit isopentenyl pyrophosphate isomerase/farnesyl pyrophosphate synthase activity with relative potencies corresponding to their antiresorptive potencies in vitro and in vivo.
    Biochemical and biophysical research communications, 1999, Feb-16, Volume: 255, Issue:2

    Topics: Animals; Bone Resorption; Brain; Carbon-Carbon Double Bond Isomerases; Cattle; Clodronic Acid; Dimethylallyltranstransferase; Diphosphonates; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Hemiterpenes; Ibandronic Acid; Mice; Multienzyme Complexes; Nitrogen; Pamidronate

1999
Bisphosphonates suppress bone resorption by a direct effect on early osteoclast precursors without affecting the osteoclastogenic capacity of osteogenic cells: the role of protein geranylgeranylation in the action of nitrogen-containing bisphosphonates on
    Bone, 2002, Volume: 30, Issue:1

    Topics: Animals; Bone Resorption; Calcium; Diphosphonates; In Vitro Techniques; Mice; Osteoblasts; Osteoclasts; Osteogenesis; Protein Prenylation; Stem Cells; Temperature

2002
Olpadronate prevents the bone loss induced by cyclosporine in the rat.
    Calcified tissue international, 2002, Volume: 70, Issue:1

    Topics: Absorptiometry, Photon; Administration, Oral; Alkaline Phosphatase; Amino Acids; Animals; Bone and Bones; Bone Density; Bone Resorption; Cyclosporine; Diphosphonates; Disease Models, Animal; Dose-Response Relationship, Drug; Immunosuppressive Agents; In Vitro Techniques; Injections, Intraperitoneal; Male; Rats; Rats, Sprague-Dawley; Treatment Outcome

2002
Modulation of PTH-stimulated osteoclastic resorption by bisphosphonates in fetal mouse bone explants.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1991, Volume: 6, Issue:11

    Topics: Animals; Bone Resorption; Calcium; Clodronic Acid; Culture Techniques; Diphosphonates; Dose-Response Relationship, Drug; Drug Synergism; Female; Mice; Mice, Inbred Strains; Pamidronate; Parathyroid Hormone; Pregnancy

1991
The role of 1,25-dihydroxyvitamin D in the maintenance of hypercalcemia in a patient with an ovarian carcinoma producing parathyroid hormone-related protein.
    Cancer, 1991, Aug-01, Volume: 68, Issue:3

    Topics: Aged; Bone Resorption; Calcitriol; Calcium; Diphosphonates; Female; Humans; Hypercalcemia; Ovarian Neoplasms; Pamidronate; Paraneoplastic Endocrine Syndromes; Parathyroid Hormone-Related Protein; Proteins

1991
Application of an in vitro model and a clinical protocol in the assessment of the potency of a new bisphosphonate.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1989, Volume: 4, Issue:5

    Topics: Administration, Oral; Aged; Animals; Bone and Bones; Bone Resorption; Clinical Protocols; Diphosphonates; Humans; Hydroxyproline; Infusions, Intravenous; Mice; Middle Aged; Models, Biological; Organ Culture Techniques; Osteitis Deformans; Pamidronate; Prospective Studies

1989
Migration and phenotypic transformation of osteoclast precursors into mature osteoclasts: the effect of a bisphosphonate.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1988, Volume: 3, Issue:2

    Topics: Animals; Bone Marrow Cells; Bone Matrix; Bone Resorption; Cell Adhesion; Cell Communication; Cell Movement; Diphosphonates; Female; Fetus; Liver; Mice; Organ Culture Techniques; Osteoclasts

1988