olomoucine and Disease Models, Animal

olomoucine has been researched along with Disease Models, Animal in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (75.00)29.6817
2010's1 (8.33)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Braisted, J; Dranchak, P; Earnest, TW; Gu, X; Hoon, MA; Inglese, J; Oliphant, E; Solinski, HJ1
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1
Djukic, ND; Jayaseelan, JSP; Muyderman, H; Sims, NR; Woodman, RJ; Yew, WP1
Bu, B; Chakrabarty, P; Li, J; Vincent, I; Zhang, M1
Tian, DS; Wang, P; Wang, W; Xie, MJ; Xu, YL; Yu, ZY; Zhang, GB1
Bu, BT; Tian, DS; Wang, W; Witte, OW; Xie, MJ; Yu, ZY1
Chen, B; Chen, C; Tian, DS; Wang, W; Wang, YH; Xie, MJ; Yu, ZY; Zhang, Q1
Bu, B; Tian, D; Wang, W; Xie, M; Yu, Z; Zhang, L; Zhang, Q; Zhu, S; Zhu, Z1
Dong, Q; He, Y; Pan, DJ; Tian, DS; Wang, W; Xie, MJ; Yu, ZY1
Bu, BT; Redecker, C; Tian, DS; Wang, W; Witte, OW; Xie, MJ; Yu, ZY; Zhang, L1
Bertotto, ME; Bignante, EA; Bussolino, DF; Mlewski, EC; Molina, VA; Paglini, G; Rodriguez Manzanares, PA1
Bhide, PG; Bruck, W; Dirnagl, U; Endres, M; Gertz, K; Harms, C; Hauck, L; Hirt, L; Hortnagl, H; Katchanov, J; Priller, J; von Harsdorf, R; Waeber, C1

Other Studies

12 other study(ies) available for olomoucine and Disease Models, Animal

ArticleYear
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
    Science translational medicine, 2019, 07-10, Volume: 11, Issue:500

    Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, Spinal; Humans; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pruritus; Receptors, Atrial Natriuretic Factor; Reproducibility of Results; Signal Transduction; Small Molecule Libraries

2019
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020
Differential effects of the cell cycle inhibitor, olomoucine, on functional recovery and on responses of peri-infarct microglia and astrocytes following photothrombotic stroke in rats.
    Journal of neuroinflammation, 2021, Jul-31, Volume: 18, Issue:1

    Topics: Animals; Astrocytes; Cell Cycle; Disease Models, Animal; Gliosis; Kinetin; Male; Microglia; Motor Cortex; Neurons; Rats; Rats, Sprague-Dawley; Recovery of Function; Stroke

2021
Cyclin-dependent kinase inhibitors attenuate protein hyperphosphorylation, cytoskeletal lesion formation, and motor defects in Niemann-Pick Type C mice.
    The American journal of pathology, 2004, Volume: 165, Issue:3

    Topics: Animals; Apoptosis; Cyclin-Dependent Kinases; Cytoskeleton; Disease Models, Animal; Enzyme Inhibitors; Female; Humans; Intracellular Signaling Peptides and Proteins; Kinetin; Male; Mice; Mice, Inbred BALB C; Mice, Neurologic Mutants; Motor Activity; Nerve Degeneration; Neurons; Niemann-Pick C1 Protein; Niemann-Pick Diseases; Phosphorylation; Proteins; Purines; Purkinje Cells; Roscovitine; tau Proteins

2004
[Effects of cyclin dependent protein kinase inhibitor olomoucine on the microenvironment of axonal regeneration after spinal cord injury: an experiment with rats].
    Zhonghua yi xue za zhi, 2006, Apr-04, Volume: 86, Issue:13

    Topics: Animals; Axons; Blotting, Western; Cyclin-Dependent Kinases; Cyclins; Disease Models, Animal; Enzyme Inhibitors; Fluoroimmunoassay; GAP-43 Protein; Glial Fibrillary Acidic Protein; Kinetin; Nerve Regeneration; Proliferating Cell Nuclear Antigen; Random Allocation; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries

2006
Suppression of astroglial scar formation and enhanced axonal regeneration associated with functional recovery in a spinal cord injury rat model by the cell cycle inhibitor olomoucine.
    Journal of neuroscience research, 2006, Volume: 84, Issue:5

    Topics: Analysis of Variance; Animals; Astrocytes; Behavior, Animal; Blotting, Western; Cell Count; Cell Cycle Proteins; Cell Proliferation; Cicatrix; Disease Models, Animal; Enzyme Inhibitors; Female; Immunohistochemistry; In Situ Nick-End Labeling; Kinetin; Nerve Regeneration; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord Injuries; Time Factors; Up-Regulation

2006
Cell cycle inhibition attenuates microglia induced inflammatory response and alleviates neuronal cell death after spinal cord injury in rats.
    Brain research, 2007, Mar-02, Volume: 1135, Issue:1

    Topics: Analysis of Variance; Animals; Brain Edema; CD11b Antigen; Cell Cycle; Cell Death; Cell Proliferation; Cytokines; Disease Models, Animal; DNA Fragmentation; Enzyme Inhibitors; Female; Immunohistochemistry; Ki-67 Antigen; Kinetin; Microglia; Neurons; Phosphopyruvate Hydratase; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries

2007
Inhibiting cell cycle progression reduces reactive astrogliosis initiated by scratch injury in vitro and by cerebral ischemia in vivo.
    Glia, 2007, Apr-01, Volume: 55, Issue:5

    Topics: Analysis of Variance; Animals; Astrocytes; Brain Injuries; Brain Ischemia; Cell Cycle; Cell Death; Cells, Cultured; Cyclin D1; Disease Models, Animal; Enzyme Inhibitors; Gliosis; Ki-67 Antigen; Kinetin; Male; Mice; Mice, Knockout; Middle Cerebral Artery; Rats; Rats, Wistar; Statistics, Nonparametric; Wounds and Injuries

2007
Attenuation of astrogliosis by suppressing of microglial proliferation with the cell cycle inhibitor olomoucine in rat spinal cord injury model.
    Brain research, 2007, Jun-18, Volume: 1154

    Topics: Analysis of Variance; Animals; CD11b Antigen; Cell Proliferation; Disease Models, Animal; Enzyme Inhibitors; Female; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Gliosis; Ki-67 Antigen; Kinetin; Microglia; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spinal Cord Injuries; Time Factors

2007
Rat focal cerebral ischemia induced astrocyte proliferation and delayed neuronal death are attenuated by cyclin-dependent kinase inhibition.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2008, Volume: 15, Issue:3

    Topics: Animals; Astrocytes; Brain Ischemia; Cell Death; Cell Proliferation; Disease Models, Animal; Drug Interactions; Enzyme Inhibitors; Glial Fibrillary Acidic Protein; In Situ Nick-End Labeling; Kinetin; Male; Neurons; Phosphopyruvate Hydratase; Rats; Rats, Wistar; Time Factors

2008
Involvement of septal Cdk5 in the emergence of excessive anxiety induced by stress.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2008, Volume: 18, Issue:8

    Topics: Analysis of Variance; Animals; Anxiety; Behavior, Animal; Cyclin-Dependent Kinase 5; Disease Models, Animal; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Kinetin; Male; Maze Learning; Rats; Rats, Wistar; Septum of Brain; Stress, Psychological

2008
Mild cerebral ischemia induces loss of cyclin-dependent kinase inhibitors and activation of cell cycle machinery before delayed neuronal cell death.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Jul-15, Volume: 21, Issue:14

    Topics: Animals; Brain Ischemia; Bromodeoxyuridine; CDC2-CDC28 Kinases; Cell Cycle; Cell Cycle Proteins; Cell Death; Cell Hypoxia; Cells, Cultured; Cyclin D1; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Disease Models, Animal; Enzyme Inhibitors; Glucose; In Situ Nick-End Labeling; Kinetin; Mice; Mice, Inbred Strains; Microtubule-Associated Proteins; Neurons; Oxygen; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Purines; Rats; Rats, Wistar; Tumor Suppressor Proteins

2001