olmesartan has been researched along with Disease Models, Animal in 69 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 25 (36.23) | 29.6817 |
| 2010's | 35 (50.72) | 24.3611 |
| 2020's | 9 (13.04) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Darwish, SF; El-Dakroury, WA; Radwan, E; Sallam, AM | 1 |
| Chen, SJ; Chian, CF; Huang, HC; Liaw, WJ; Shih, CC; Tsai, HJ; Tsao, CM; Wu, CC | 1 |
| Bae, EH; Choi, HS; Kim, CS; Kim, IJ; Kim, SW; Ma, SK; Scholey, JW; Suh, SH | 1 |
| Chen, M; Jiang, Z; Li, Y; Peng, Y; Shi, S; Song, J | 1 |
| Chen, DR; Chen, J; Gao, PJ; Han, WQ; Jiang, H; Ruan, CC | 1 |
| Asai, K; Kamiya, M; Mizuno, K; Murai, K; Noma, S; Sato, N; Shimizu, W; Shirakabe, A | 1 |
| Ahn, B; Hall, SE; Hinkley, JM; Hyatt, H; Morton, AB; Powers, SK; Smuder, AJ; Sollanek, KJ; Wiggs, MP | 1 |
| Bae, EH; Choi, HS; Kim, CS; Kim, IJ; Kim, SW; Ma, SK; Mathew, AP; Park, IK; Suh, SH; Vasukutty, A | 1 |
| Abe, E; Azushima, K; Hashimoto, T; Kamimura, D; Kinguchi, S; Nakano, M; Sano, D; Suzuki, T; Taguchi, S; Tamura, K; Tanaka, S; Tsukamoto, S; Urate, S; Wakui, H; Yamada, T; Yamaji, T; Yamashita, A | 1 |
| Abdo, WS; El-Ahwany, E; Khalil, RM; Nassif, D; Saber, S | 1 |
| Ahn, CM; Choi, D; Hong, MK; Hong, SJ; Jang, Y; Kim, BK; Kim, CK; Kim, JS; Kim, SH; Ko, YG; Lee, JJ; Lee, OH; Lee, SG; Lee, SH; Lee, SJ; Oh, J; Park, S; Thuy, NVP | 1 |
| Casella, AM; de Noronha, L; Grobe, SF; Luchini, A; Martins, Ide C; Precoma, DB; Sturzeneker, MC; Torres, CL; Torres, Rdo R; Torres, RJ | 1 |
| Lam, L; Nakano, D; Nishiyama, A; Ortiz, RM; Peti-Peterdi, J; Popovich, I; Rodriguez, R; Sonanez-Organis, JG; Thorwald, MA; Vázquez-Medina, JP; Viscarra, JA | 1 |
| Dimitriadis, F; Kinoshita, Y; Martin, DT; Ohmasa, F; Oikawa, R; Oiwa, H; Saito, M; Satoh, I; Shimizu, S; Tomita, S; Tsounapi, P | 1 |
| Miura, S; Saku, K | 1 |
| Halleck, F; Holleck-Weithmann, S; Kossmehl, P; Kreutz, R; Rothermund, L; Schröder, K | 1 |
| Abe, K; Deguchi, K; Hishikawa, N; Ikeda, Y; Kono, S; Kurata, T; Liu, W; Omote, Y; Yamashita, T | 1 |
| Azushima, K; Kanaoka, T; Kobayashi, R; Maeda, A; Matsuda, M; Ohki, K; Ohsawa, M; Tamura, K; Tokita, Y; Tsurumi-Ikeya, Y; Umemura, S; Uneda, K; Wakui, H; Yamashita, A | 1 |
| Hirose, M; Kashihara, T; Matsushita, N; Mende, U; Nakada, T; Sanbe, A; Shimojo, H; Suzuki, S; Taira, E; Takeishi, Y; Yamada, M | 1 |
| Díez-Tejedor, E; Fuentes, B; Gutiérrez-Fernández, M; Otero-Ortega, L; Ramos-Cejudo, J; Rodríguez-Frutos, B | 1 |
| Brito, GA; Cavalcanti, Pde F; de Araújo, AA; de Araújo, RF; de Medeiros, CA; de Moura Freire, MA; Freire, MA; Reinaldo, MP | 1 |
| Ding, Z; Ge, J; Gong, H; Jiang, G; Li, Y; Wang, S; Wang, X; Wu, J; Ye, Y; Yin, P; Yuan, J; Zhang, W; Zhou, J; Zou, Y | 1 |
| Araújo, TE; Borba, PB; da Silva, AI; de Araújo Júnior, RF; de Araújo, AA; de Souza, FH; Nogueira, AC; Saldanha, TS | 1 |
| Bi, YW; Chen, KB; Lu, X | 1 |
| Hasegawa, Y; Kim-Mitsuyama, S; Matsui, K; Nakagata, N; Nakagawa, T; Senju, S; Uekawa, K | 1 |
| Chen, J; Chen, M; Gu, J; He, L; Hu, H; Jing, Y; Li, L; Mei, C; Mei, S; Qi, N; Song, S; Sun, L; Wu, M; Wüthrich, RP; Yang, M | 1 |
| Hasegawa, Y; Kim-Mitsuyama, S; Nakagawa, T; Uekawa, K | 1 |
| Fukumoto, Y; Ito, K; Nawata, J; Onoue, N; Shimokawa, H; Sugimura, K; Tada, T; Wang, H; Zhulanqiqige, D | 1 |
| Azuma, K; Horiuchi, M; Kimura, K; Masuda, S; Matsuda, M; Mogi, M; Ozawa, M; Shigenaga, A; Tamura, K; Tsurumi-Ikeya, Y; Uchino, K; Umemura, S; Wakui, H | 1 |
| Fukamizu, A; Honjo, K; Inaba, S; Ishida, J; Nakamura, S; Sakairi, A; Sugiyama, F; Yagami, K | 1 |
| Fukuda, Y; Iino, Y; Ishizaki, M; Katayama, Y; Kawachi, H; Masuda, Y; Mii, A; Shimizu, A | 1 |
| Fukuda, I; Fukui, K; Minakawa, M; Suzuki, Y | 1 |
| Katsurada, A; Kobori, H; Miyata, K; Ohashi, N; Saito, T; Satou, R; Urushihara, M | 1 |
| Kano, M; Kurinami, H; Morishita, R; Niisato, K; Ogihara, T; Rakugi, H; Sato, N; Shinohara, M; Takeda, S; Takeuchi, D | 1 |
| Fukushima, H; Ishimitsu, T; Kobayashi, N; Koguchi, W; Takeshima, H | 1 |
| Aki, K; Arai, T; Fujita, E; Fukuda, Y; Fukunaga, Y; Ishikawa, A; Kuwahara, N; Masuda, Y; Mii, A; Natori, Y; Shimizu, A | 1 |
| Dai, W; Hale, SL; Jyrala, AJ; Kay, GL; Kloner, RA | 1 |
| Eldawoody, H; Kimura, N; Nakayama, T; Saito, A; Shimizu, H; Takahashi, A; Tominaga, T | 1 |
| Hosoya, M; Ohashi, J; Sawada, A; Shimokawa, H; Takaki, A | 1 |
| Kitagawa, K; Omura-Matsuoka, E; Oyama, N; Sakoda, S; Sasaki, T; Sugiyama, Y; Terasaki, Y; Yagita, Y | 1 |
| Kato, M; Mizuno, M; Sada, T; Terashima, H; Tsuchida, H; Yasumo, H | 1 |
| Chen, R; Eisner, C; Hu, X; Huang, Y; Kopp, JB; Leelahavanichkul, A; Mizel, D; Schnermann, J; Star, RA; Wright, EC; Yan, Q; Yuen, PS; Zhou, H | 1 |
| Fukaya, H; Hirasawa, S; Izumi, T; Kiryu, M; Masaki, Y; Moriguchi, M; Niwano, H; Niwano, S; Sato, D | 1 |
| Ioshii, SO; Précoma, DB; Sturzeneker, MC; Villela Baroncini, LA | 1 |
| Hara, T; Hayden, MR; Hitomi, H; Ichimura, A; Ito, S; Kaifu, K; Kawachi, H; Kiyomoto, H; Kobori, H; Kohno, M; Matsumoto, S; Nishijima, Y; Nishiyama, A; Ohsaki, H; Sofue, T; Sowers, JR; Urushihara, M; Whaley-Connell, A | 1 |
| Aoyama, Y; Fukaya, H; Izumi, T; Kiryu, M; Kishihara, J; Masaki, Y; Niwano, H; Niwano, S | 1 |
| Hamada, J; Kobara, M; Nakata, T; Noda, K; Shiraishi, T; Tanaka, T; Toba, H; Wang, J; Yoshifuji, Y | 1 |
| Chuang, YC; Fang, KM; Su, YK; Wu, MS | 1 |
| Baylis, C; Moningka, NC; Sasser, JM; Tsarova, T | 1 |
| Ge, J; Guo, J; Jiang, G; Li, L; Wang, S; Wu, J; You, J; Zou, Y | 1 |
| Fujita, M; Hirata, A; Hori, M; Kitakaze, M; Liao, Y; Minamino, T; Nagamachi, Y; Nakatani, T; Ogawa, S; Okada, K; Ozawa, K; Takashima, S; Tomoike, H; Tsukamoto, O; Tsukamoto, Y; Yutani, C | 1 |
| Arakawa, N; Fujimori, I; Inoue, T; Nakamura, H; Shimakawa, E; Shimizu, Y; Toyoshi, T; Yokoyama, T; Yoshigae, Y | 1 |
| Fischer, JW; Fritzenkötter, C; Li, J; Sandmann, S; Spormann, J; Tiede, K; Unger, T | 1 |
| Chen, R; Horiuchi, M; Ide, A; Iwai, M; Iwanami, J; Mogi, M; Tomochika, H; Tomono, Y | 1 |
| Achard, JM; Faure, S; Fournier, A; Javellaud, J; Oudart, N; Warnock, DG | 1 |
| Dong, YF; Kataoka, K; Kim-Mitsuyama, S; Lai, ZF; Matsuba, S; Ogawa, H; Tanaka, T; Tokutomi, Y; Yamamoto, E; Yamashita, T | 1 |
| Hiramatsu, N; Hiromura, K; Ideura, H; Ikeuchi, H; Kaneko, Y; Kopp, JB; Kuroiwa, T; Nojima, Y; Sakurai, N; Shigehara, T; Takeuchi, S; Tomioka, M; Ueki, K | 1 |
| Fujimoto, N; Matsumoto, T; Nishii, H; Nomura, M; Ozaki, Y | 1 |
| Haruna, Y; Kashihara, N; Kobayashi, S; Komai, N; Namikoshi, T; Sasaki, T; Satoh, M; Tomita, N | 1 |
| Kumagai, K; Nakashima, H | 1 |
| Ito, M; Izuhara, Y; Miyata, T; Ohtomo, S; Van Ypersele De Strihou, C | 1 |
| de Bold, AJ; Georgalis, T; Kuroski de Bold, ML; Ogawa, T; Veinot, JP | 1 |
| Kang, JJ; Meer, EJ; Peti-Peterdi, J; Sipos, A; Toma, I; Vargas, SL | 1 |
| Guo, Q; Ito, O; Kanazawa, M; Kohzuki, M; Kurosawa, H; Minami, N; Mori, N; Nagasaka, M | 1 |
| Ferrario, CM; Igase, M; Kohara, K; Miki, T; Nagai, T | 1 |
| Fujimura, M; Ichikawa, Y; Inuzuka, K; Nakao, S; Nishizawa, Y; Tagami, A; Takato, H; Waseda, Y; Yasui, M | 1 |
| Ando, H; Ishikura, K; Kaneko, S; Kita, Y; Kurita, S; Matsuzawa-Nagata, N; Misu, H; Nabemoto, S; Nakanuma, Y; Ota, T; Takamura, T; Uno, M; Zen, Y | 1 |
| Hosokawa, T; Inoue, T; Koike, H; Mori, Y; Sasaki, Y; Yanagisawa, H; Yokoyoma, T | 1 |
1 review(s) available for olmesartan and Disease Models, Animal
| Article | Year |
|---|---|
Recent progress in the treatment of cardiovascular disease using olmesartan.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Coronary Artery Disease; Coronary Stenosis; Disease Models, Animal; Humans; Hypertension; Imidazoles; Plaque, Atherosclerotic; Tetrazoles | 2014 |
1 trial(s) available for olmesartan and Disease Models, Animal
| Article | Year |
|---|---|
Different protective and reparative effects of olmesartan in stroke according to time of administration and withdrawal.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Double-Blind Method; Drug Administration Schedule; Female; Glial Fibrillary Acidic Protein; Imidazoles; In Situ Nick-End Labeling; Magnetic Resonance Imaging; Male; NADPH Oxidase 4; NADPH Oxidases; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Statistics, Nonparametric; Stroke; Tetrazoles; Time Factors; Vascular Endothelial Growth Factor A | 2015 |
67 other study(ies) available for olmesartan and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Olmesartan niosomes ameliorates the Indomethacin-induced gastric ulcer in rats: Insights on MAPK and Nrf2/HO-1 signaling pathway.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Disease Models, Animal; Drug Liberation; Gastric Mucosa; Heme Oxygenase (Decyclizing); Humans; Imidazoles; Indomethacin; Liposomes; Male; MAP Kinase Signaling System; NF-E2-Related Factor 2; Rats; Stomach Ulcer; Tetrazoles | 2021 |
Olmesartan Ameliorates Organ Injury and Mortality in Rats With Peritonitis-Induced Sepsis.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Cecum; Disease Models, Animal; Humans; Imidazoles; Interleukin-6; Nitric Oxide; Olmesartan Medoxomil; Peritonitis; Rats; Rats, Wistar; Sepsis; Tetrazoles | 2022 |
Olmesartan Attenuates Kidney Fibrosis in a Murine Model of Alport Syndrome by Suppressing Tubular Expression of TGFβ.
Topics: Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Apoptosis; Biomarkers; Biopsy; Disease Models, Animal; Fibrosis; Gene Expression Regulation; Imidazoles; Kidney Tubules; Mice; Mice, Knockout; Nephritis, Hereditary; Peptidyl-Dipeptidase A; ras Proteins; Tetrazoles; Transforming Growth Factor beta; Treatment Outcome | 2019 |
High-dose nitrate therapy recovers the expression of subtypes α
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Disease Models, Animal; Drug Therapy, Combination; Heart Failure; Imidazoles; Isosorbide Dinitrate; Kidney Cortex; Male; Myocardial Infarction; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta; Receptors, Angiotensin; Renin-Angiotensin System; Tetrazoles; Time Factors | 2020 |
Involvement of Angiotensin II Type 1 Receptor and Calcium Channel in Vascular Remodeling and Endothelial Dysfunction in Rats with Pressure Overload.
Topics: Amlodipine; Animals; Calcium Channels; Carotid Artery Injuries; Constriction, Pathologic; Disease Models, Animal; Hyperplasia; Imidazoles; Male; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Tetrazoles; Tumor Necrosis Factor-alpha; Vascular Remodeling | 2020 |
Effect of Gonadectomy and Angiotensin II Receptor Blockade in a Mouse Model of Isoproterenol-induced Cardiac Diastolic Dysfunction.
Topics: Angiotensin Receptor Antagonists; Animals; Cardiomegaly; Castration; Diastole; Disease Models, Animal; Echocardiography; Female; Heart Failure; Heart Ventricles; Humans; Imidazoles; Isoproterenol; Male; Mice, Inbred Strains; Stroke Volume; Tetrazoles | 2021 |
Comparative Efficacy of Angiotensin II Type 1 Receptor Blockers Against Ventilator-Induced Diaphragm Dysfunction in Rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Atrophy; Diaphragm; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Humans; Imidazoles; Irbesartan; Rats; Respiration, Artificial; Tetrazoles; Ventilators, Mechanical | 2021 |
Kidney-accumulating olmesartan-loaded nanomicelles ameliorate the organ damage in a murine model of Alport syndrome.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Disease Models, Animal; Imidazoles; Kidney; Mice; Nephritis, Hereditary; Tetrazoles | 2021 |
Tissue-specific expression of the SARS-CoV-2 receptor, angiotensin-converting enzyme 2, in mouse models of chronic kidney disease.
Topics: Adenine; Angiotensin-Converting Enzyme 2; Animals; Aristolochic Acids; COVID-19; Disease Models, Animal; Down-Regulation; Humans; Imidazoles; Kidney; Mice; Mice, Inbred C57BL; Organ Specificity; Renal Insufficiency, Chronic; SARS-CoV-2; Tetrazoles | 2021 |
Olmesartan ameliorates chemically-induced ulcerative colitis in rats via modulating NFκB and Nrf-2/HO-1 signaling crosstalk.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Apoptosis; Apoptosis Regulatory Proteins; Colitis, Ulcerative; Colon; Cytokines; Disease Models, Animal; Heme Oxygenase (Decyclizing); Imidazoles; Inflammation Mediators; Male; NF-E2-Related Factor 2; NF-kappa B; NF-KappaB Inhibitor alpha; Oxidative Stress; Rats, Wistar; Signal Transduction; Tetrazoles; Transcription Factor RelA | 2019 |
Synergistic protective effects of a statin and an angiotensin receptor blocker for initiation and progression of atherosclerosis.
Topics: Angiotensin Receptor Antagonists; Animals; Atherosclerosis; Cell Polarity; Disease Models, Animal; Drug Synergism; Imidazoles; Macrophages; Male; Mice; Rabbits; RAW 264.7 Cells; Rosuvastatin Calcium; Tetrazoles; Treatment Outcome | 2019 |
Effect of olmesartan on leukocyte recruitment in choroid-sclera complex in hypercholesterolemia model.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Biomarkers; Blood Glucose; Chemokine CCL2; Chemotaxis, Leukocyte; Choroid; Disease Models, Animal; Hypercholesterolemia; Imidazoles; Lipids; Macrophages; Macular Degeneration; Male; Rabbits; Sclera; Tetrazoles | 2013 |
Angiotensin receptor-mediated oxidative stress is associated with impaired cardiac redox signaling and mitochondrial function in insulin-resistant rats.
Topics: Aldehydes; Angiotensin II Type 1 Receptor Blockers; Animals; Catalase; Citrate (si)-Synthase; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Glutathione Peroxidase; Imidazoles; Insulin Resistance; Male; Membrane Glycoproteins; Mitochondria, Heart; Myocardium; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; NF-E2-Related Factor 2; Obesity; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Inbred OLETF; Receptor, Angiotensin, Type 1; RNA, Messenger; Signal Transduction; Succinate Dehydrogenase; Superoxide Dismutase; Tetrazoles; Time Factors; Tyrosine | 2013 |
Olmesartan ameliorates urinary dysfunction in the spontaneously hypertensive rat via recovering bladder blood flow and decreasing oxidative stress.
Topics: Aldehydes; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Biomarkers; Blood Pressure; Disease Models, Animal; Hypertension; Imidazoles; Male; Malondialdehyde; Nerve Growth Factor; NF-E2-Related Factor 2; Nifedipine; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Wistar; Regional Blood Flow; Tetrazoles; Urinary Bladder; Urinary Bladder Diseases; Urodynamics | 2014 |
Cardiorenal protection in experimental hypertension with renal failure: comparison between vasopeptidase inhibition and angiotensin receptor blockade.
Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Rats, Wistar; Receptors, Angiotensin; Renal Insufficiency; Tetrazoles | 2015 |
Synergistic neuroprotective effects of combined treatment with olmesartan plus azelnidipine in stroke-prone spontaneously hypertensive rats.
Topics: Age Factors; Animals; Azetidinecarboxylic Acid; Blood Pressure; Brain Injuries; Chemokine CCL2; Collagen Type IV; Dihydropyridines; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Gene Expression Regulation; Heart Rate; Imidazoles; Laser-Doppler Flowmetry; Male; Matrix Metalloproteinase 9; Motor Activity; Oxidative Stress; Rats; Rats, Inbred SHR; Stroke; Tetrazoles | 2014 |
Effects of the Angiotensin receptor blocker olmesartan on adipocyte hypertrophy and function in mice with metabolic disorders.
Topics: Adipocytes; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Body Weight; Disease Models, Animal; Gene Expression Regulation; Humans; Hypertrophy; Imidazoles; Interleukin-6; Metabolic Diseases; Mice; Obesity, Abdominal; Tetrazoles | 2014 |
Cardiac overexpression of constitutively active Galpha q causes angiotensin II type1 receptor activation, leading to progressive heart failure and ventricular arrhythmias in transgenic mice.
Topics: Adaptor Proteins, Signal Transducing; Animals; Atrial Natriuretic Factor; Collagen Type I; Disease Models, Animal; Gene Expression Regulation; GTP-Binding Protein alpha Subunits, Gq-G11; Heart Failure; Imidazoles; Mice; Mice, Transgenic; Myosin Heavy Chains; Tetrazoles; Ventricular Premature Complexes | 2014 |
Olmesartan decreased levels of IL-1β and TNF-α, down-regulated MMP-2, MMP-9, COX-2, RANK/RANKL and up-regulated SOCs-1 in an intestinal mucositis model.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Bacteremia; Cyclooxygenase 2; Cytokines; Disease Models, Animal; Down-Regulation; Imidazoles; Immunohistochemistry; Interleukin-1beta; Intestine, Small; Leukocytosis; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Methotrexate; Mucositis; RANK Ligand; Rats; Rats, Wistar; Receptor Activator of Nuclear Factor-kappa B; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling Proteins; Tetrazoles; Tumor Necrosis Factor-alpha; Up-Regulation | 2014 |
Combination Treatment With Antihypertensive Agents Enhances the Effect of Qiliqiangxin on Chronic Pressure Overload-induced Cardiac Hypertrophy and Remodeling in Male Mice.
Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Apoptosis; Autophagy; Blood Pressure; Captopril; Chronic Disease; Disease Models, Animal; Drug Therapy, Combination; Drugs, Chinese Herbal; Gene Expression Regulation; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Male; Metoprolol; Mice, Inbred C57BL; Myocytes, Cardiac; Signal Transduction; Tetrazoles; Ventricular Function, Left; Ventricular Remodeling | 2015 |
In a methotrexate-induced model of intestinal mucositis, olmesartan reduced inflammation and induced enteropathy characterized by severe diarrhea, weight loss, and reduced sucrose activity.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Diarrhea; Disease Models, Animal; Imidazoles; Inflammation; Interleukin-1beta; Intestinal Mucosa; Intestine, Small; Male; Methotrexate; Mucositis; Neoplasms; Olmesartan Medoxomil; Rats, Wistar; Sucrose; Tetrazoles; Tumor Necrosis Factor-alpha; Weight Loss | 2015 |
Olmesartan restores the protective effect of remote ischemic perconditioning against myocardial ischemia/reperfusion injury in spontaneously hypertensive rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Disease Models, Animal; Imidazoles; Ischemic Preconditioning, Myocardial; Myocardial Reperfusion Injury; Random Allocation; Rats; Rats, Inbred SHR; Tetrazoles | 2015 |
Transient Mild Cerebral Ischemia Significantly Deteriorated Cognitive Impairment in a Mouse Model of Alzheimer's Disease via Angiotensin AT1 Receptor.
Topics: Alzheimer Disease; Angiotensin II Type 1 Receptor Blockers; Animals; Cerebrovascular Circulation; Cognitive Dysfunction; Disease Models, Animal; Dose-Response Relationship, Drug; Imidazoles; Ischemic Attack, Transient; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Receptor, Angiotensin, Type 1; Tetrazoles | 2017 |
Olmesartan Prevents Microalbuminuria in db/db Diabetic Mice Through Inhibition of Angiotensin II/p38/SIRT1-Induced Podocyte Apoptosis.
Topics: Albuminuria; Angiotensin II; Animals; Apoptosis; Cell Line; Diabetic Nephropathies; Disease Models, Animal; Imidazoles; Male; Mice; Mice, Inbred Strains; p38 Mitogen-Activated Protein Kinases; Podocytes; Sirtuin 1; Tetrazoles | 2016 |
Chronic kidney disease accelerates cognitive impairment in a mouse model of Alzheimer's disease, through angiotensin II.
Topics: Aging; Alzheimer Disease; Angiotensin II Type 1 Receptor Blockers; Animals; Blood-Brain Barrier; Cognition; Cognitive Dysfunction; Disease Models, Animal; Hippocampus; Imidazoles; Maze Learning; Memory; Mice; Mice, Transgenic; Oxidative Stress; Renal Insufficiency, Chronic; Tetrazoles | 2017 |
Enhanced pulsatile pressure accelerates vascular smooth muscle migration: implications for atherogenesis of hypertension.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Atherosclerosis; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Calcium Signaling; Cell Movement; Cells, Cultured; Dihydropyridines; Disease Models, Animal; Equipment and Supplies; Estrenes; Hypertension; Imidazoles; Inositol 1,4,5-Trisphosphate Receptors; Macrocyclic Compounds; Muscle, Smooth, Vascular; Oxazoles; Pyrrolidinones; Rats; Rats, Wistar; Signal Transduction; Tetrazoles; Type C Phospholipases | 2008 |
Effect of olmesartan on tissue expression balance between angiotensin II receptor and its inhibitory binding molecule.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Blotting, Western; Disease Models, Animal; Gene Expression; Heart Ventricles; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Tetrazoles; Ventricular Remodeling | 2008 |
Angiotensin type 1 receptor blockade prevents cardiac remodeling in mice with pregnancy-associated hypertension.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Cardiomegaly; Disease Models, Animal; Female; Fibrosis; Hypertension, Pregnancy-Induced; Imidazoles; Male; Mice; Mice, Transgenic; Myocardium; Pregnancy; Receptor, Angiotensin, Type 1; Signal Transduction; Tetrazoles; Ventricular Remodeling | 2008 |
Angiotensin II receptor blockade inhibits acute glomerular injuries with the alteration of receptor expression.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Becaplermin; Biomarkers; Blood Pressure; Cell Proliferation; Disease Models, Animal; Fluorescent Antibody Technique, Indirect; Glomerular Mesangium; Glomerulonephritis, Membranoproliferative; Imidazoles; Kidney Glomerulus; Male; Platelet-Derived Growth Factor; Proteinuria; Proto-Oncogene Proteins c-sis; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Tetrazoles; Thy-1 Antigens | 2009 |
Olmesartan improves left ventricular function in pressure-overload hypertrophied rat heart by blocking angiotensin II receptor with synergic effects of upregulation of angiotensin converting enzyme 2.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Cardiomegaly; Disease Models, Animal; Drug Synergism; Extracellular Signal-Regulated MAP Kinases; Heart; Humans; Imidazoles; Male; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; RNA, Messenger; Tetrazoles; Up-Regulation; Ventricular Function, Left | 2009 |
Role of activated intrarenal reactive oxygen species and renin-angiotensin system in IgA nephropathy model mice.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Blotting, Western; Cyclic N-Oxides; Disease Models, Animal; Glomerulonephritis, IGA; Imidazoles; Immunoglobulin A; Immunohistochemistry; Kidney Glomerulus; Male; Mice; Mice, Inbred Strains; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Spin Labels; Tetrazoles | 2009 |
Angiotensin receptor blocker prevented beta-amyloid-induced cognitive impairment associated with recovery of neurovascular coupling.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Angiotensin II Type 1 Receptor Blockers; Animals; Cerebrovascular Circulation; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Hippocampus; Imidazoles; Male; Maze Learning; Mice; Mice, Transgenic; Microcirculation; Neuronal Plasticity; Oxidative Stress; Peptide Fragments; Reactive Oxygen Species; Renin-Angiotensin System; Tetrazoles | 2009 |
Effects of olmesartan on Apelin/APJ and Akt/endothelial nitric oxide synthase pathway in Dahl rats with end-stage heart failure.
Topics: Adipokines; Angiotensin II Type 1 Receptor Blockers; Animals; Apelin; Apelin Receptors; Carrier Proteins; Disease Models, Animal; Down-Regulation; Heart Failure; Imidazoles; Intercellular Signaling Peptides and Proteins; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred Dahl; Receptors, G-Protein-Coupled; Signal Transduction; Tetrazoles | 2010 |
ANG II receptor blockade enhances anti-inflammatory macrophages in anti-glomerular basement membrane glomerulonephritis.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Anti-Glomerular Basement Membrane Disease; Blood Pressure; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Imidazoles; Inflammation; Kidney Glomerulus; Macrophages; Male; Rats; Rats, Inbred WKY; Tetrazoles | 2010 |
Cardioprotective effects of angiotensin II type 1 receptor blockade with olmesartan on reperfusion injury in a rat myocardial ischemia-reperfusion model.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Cardiotonic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Hemodynamics; Imidazoles; Myocardial Contraction; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Sprague-Dawley; Tetrazoles; Vasodilator Agents; Ventricular Function, Left | 2010 |
Effect of olmesartan and pravastatin on experimental cerebral aneurysms in rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Cerebral Arteries; Circle of Willis; Corrosion Casting; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Endothelial Cells; Hydralazine; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imidazoles; Intracranial Aneurysm; Microscopy, Electron, Scanning; Pravastatin; Rats; Tetrazoles; Treatment Outcome; Vasodilator Agents | 2010 |
Combination therapy with olmesartan and azelnidipine improves EDHF-mediated responses in diabetic apolipoprotein E-deficient mice.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Apolipoproteins E; Azetidinecarboxylic Acid; Biological Factors; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Dihydropyridines; Disease Models, Animal; Drug Therapy, Combination; Endothelium, Vascular; Imidazoles; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide Synthase Type III; Proto-Oncogene Proteins c-akt; Signal Transduction; Streptozocin; Tetrazoles; Vasodilation | 2010 |
An angiotensin II type 1 receptor blocker can preserve endothelial function and attenuate brain ischemic damage in spontaneously hypertensive rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Brain Infarction; Cerebrovascular Circulation; Disease Models, Animal; Endothelium; Gene Expression Regulation; Hypoxia-Ischemia, Brain; Imidazoles; Nitric Oxide Synthase Type III; Phosphorylation; Rats; Rats, Inbred SHR; Rats, Wistar; Tetrazoles; Time Factors | 2010 |
A sensitive short-term evaluation of antifibrotic effects using newly established type I collagen reporter transgenic rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzamides; Collagen; Collagen Type I; Collagen Type I, alpha 1 Chain; Dioxoles; Disease Models, Animal; Fibrosis; Genes, Reporter; Hydroxyproline; Imidazoles; Kidney; Luciferases; Male; Protein Serine-Threonine Kinases; Rats; Rats, Transgenic; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Sensitivity and Specificity; Tetrazoles; Ureteral Obstruction | 2010 |
Angiotensin II overcomes strain-dependent resistance of rapid CKD progression in a new remnant kidney mouse model.
Topics: Albuminuria; Anemia; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Chronic Disease; Desoxycorticosterone; Disease Models, Animal; Disease Progression; Fibrosis; Genetic Predisposition to Disease; Glomerulonephritis; Heart Diseases; Hydralazine; Hypertension; Imidazoles; Infusion Pumps, Implantable; Infusions, Subcutaneous; Kidney; Kidney Diseases; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Nephrectomy; Sodium Chloride, Dietary; Species Specificity; Telemetry; Tetrazoles; Time Factors; X-Ray Microtomography | 2010 |
Combined effects of up- and downstream therapies on atrial fibrillation in a canine rapid stimulation model.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Bepridil; Disease Models, Animal; Dogs; Down-Regulation; Drug Therapy, Combination; Heart Conduction System; Imidazoles; Tetrazoles; Up-Regulation | 2012 |
Olmesartan severely weakened the development of NASH in an animal model of hypercholesterolemia.
Topics: Alanine Transaminase; Angiotensin II Type 1 Receptor Blockers; Animals; Aspartate Aminotransferases; Blood Glucose; Cholesterol, Dietary; Disease Models, Animal; Fatty Liver; Hepatitis; Hypercholesterolemia; Imidazoles; Lipids; Liver; Liver Cirrhosis; Male; Non-alcoholic Fatty Liver Disease; Rabbits; Tetrazoles; Time Factors | 2011 |
Early treatment with olmesartan prevents juxtamedullary glomerular podocyte injury and the onset of microalbuminuria in type 2 diabetic rats.
Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus, Type 2; Disease Models, Animal; Hydralazine; Hydrochlorothiazide; Imidazoles; Juxtaglomerular Apparatus; Male; Membrane Proteins; Podocytes; Rats; Rats, Inbred OLETF; Reserpine; Tetrazoles | 2012 |
Angiotensin II-mediated up-regulation of connective tissue growth factor promotes atrial tissue fibrosis in the canine atrial fibrillation model.
Topics: Angiotensin II; Animals; Atrial Fibrillation; Blotting, Western; Connective Tissue Growth Factor; Disease Models, Animal; Dogs; Extracellular Matrix; Female; Heart Atria; Imidazoles; Real-Time Polymerase Chain Reaction; Signal Transduction; Tetrazoles; Up-Regulation | 2012 |
Additive amelioration of oxidative stress and cardiac function by combined mineralocorticoid and angiotensin receptor blockers in postinfarct failing hearts.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Cells, Cultured; Disease Models, Animal; Drug Therapy, Combination; Heart Failure; Hemodynamics; Imidazoles; Lipid Peroxidation; Male; Mineralocorticoid Receptor Antagonists; Myocardial Infarction; Myocardium; NADPH Oxidases; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; Spironolactone; Tetrazoles; Ventricular Function, Left | 2012 |
Effects of olmesartan on arterial stiffness in rats with chronic renal failure.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Aorta; Blood Urea Nitrogen; Creatinine; Disease Models, Animal; Glycation End Products, Advanced; Hemodynamics; Hypertrophy, Left Ventricular; Imidazoles; Kidney Failure, Chronic; Male; Malondialdehyde; Nephrectomy; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Tetrazoles; Vascular Stiffness | 2012 |
Nebivolol does not protect against 5/6 ablation/infarction induced chronic kidney disease in rats - comparison with angiotensin II receptor blockade.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzopyrans; Blotting, Western; Chromatography, High Pressure Liquid; Disease Models, Animal; Ethanolamines; Imidazoles; Infarction; Kidney Cortex; Kidney Failure, Chronic; Male; Nebivolol; Rats; Rats, Sprague-Dawley; Tetrazoles | 2012 |
Olmesartan attenuates cardiac remodeling through DLL4/Notch1 pathway activation in pressure overload mice.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Calcium-Binding Proteins; Dipeptides; Disease Models, Animal; Fibrosis; Hypertrophy, Left Ventricular; Imidazoles; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Microcirculation; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Receptor, Notch1; Tetrazoles; Up-Regulation; Ventricular Dysfunction, Left; Ventricular Remodeling | 2013 |
Prolonged endoplasmic reticulum stress in hypertrophic and failing heart after aortic constriction: possible contribution of endoplasmic reticulum stress to cardiac myocyte apoptosis.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aortic Valve Stenosis; Apoptosis; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Disease Progression; Endoplasmic Reticulum; Gene Expression Regulation; Heart Failure; Humans; Imidazoles; Ligation; Male; Mice; Mice, Inbred C57BL; Molecular Chaperones; Myocytes, Cardiac; Natriuretic Peptide, Brain; Olmesartan Medoxomil; Rats; Rats, Inbred WKY; RNA, Messenger; Signal Transduction; Stress, Physiological; Tetrazoles; Thapsigargin; Tunicamycin | 2004 |
Pharmacological and pharmacokinetic study of olmesartan medoxomil in animal diabetic retinopathy models.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Area Under Curve; Benzimidazoles; Biphenyl Compounds; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Disease Models, Animal; Dose-Response Relationship, Drug; Electroretinography; Glycated Hemoglobin; Heart Rate; Hypertension; Hypoxia; Imidazoles; Male; Olmesartan Medoxomil; Oxygen; Rats; Rats, Inbred SHR; Retinal Neovascularization; Tetrazoles | 2005 |
Differential effects of olmesartan and ramipril on inflammatory response after myocardial infarction in rats.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Cardiovascular Diseases; Cardiovascular System; Disease Models, Animal; Dose-Response Relationship, Drug; Imidazoles; Inflammation; Interleukin-1; Interleukin-6; Male; Myocardial Infarction; Placebos; Ramipril; Rats; Rats, Wistar; Renin-Angiotensin System; RNA, Messenger; Tetrazoles; Tumor Necrosis Factor-alpha | 2006 |
The calcium-channel blocker, azelnidipine, enhances the inhibitory action of AT1 receptor blockade on ischemic brain damage.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Azetidinecarboxylic Acid; Brain Ischemia; Calcium Channel Blockers; Cerebrovascular Circulation; Dihydropyridines; Disease Models, Animal; Drug Therapy, Combination; Imidazoles; Male; Mice; Mice, Inbred C57BL; Tetrazoles | 2006 |
Synergistic protective effects of erythropoietin and olmesartan on ischemic stroke survival and post-stroke memory dysfunctions in the gerbil.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Disease Models, Animal; Drug Therapy, Combination; Erythropoietin; Gerbillinae; Imidazoles; Kaplan-Meier Estimate; Male; Memory Disorders; Neuroprotective Agents; Ramipril; Recombinant Proteins; Stroke; Tetrazoles | 2006 |
Pravastatin enhances beneficial effects of olmesartan on vascular injury of salt-sensitive hypertensive rats, via pleiotropic effects.
Topics: Animals; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Endothelium, Vascular; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Imidazoles; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Pravastatin; Rats; Rats, Inbred Dahl; Reference Values; Risk Factors; Sensitivity and Specificity; Sodium Chloride, Dietary; Tetrazoles; Vascular Diseases | 2007 |
Angiotensin II type 1 receptor blockade inhibits the development and progression of HIV-associated nephropathy in a mouse model.
Topics: AIDS-Associated Nephropathy; Angiotensin II Type 1 Receptor Blockers; Animals; Black People; Disease Models, Animal; Humans; Imidazoles; Intracellular Signaling Peptides and Proteins; Kidney; Kidney Failure, Chronic; Membrane Proteins; Mice; Mice, Transgenic; Receptor, Angiotensin, Type 1; Tetrazoles | 2007 |
An angiotensin II receptor blocker increases sexual behavior in type 2 diabetic mice.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Exploratory Behavior; Female; Imidazoles; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Inbred Strains; Motor Activity; Reaction Time; Receptor, Angiotensin, Type 1; Sexual Behavior, Animal; Sexual Dysfunction, Physiological; Species Specificity; Tetrazoles; Time Factors | 2007 |
Olmesartan ameliorates renovascular injury and oxidative stress in Zucker obese rats enhanced by dietary protein.
Topics: Aldehydes; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Dietary Proteins; Disease Models, Animal; Endothelium, Vascular; Hydralazine; Hypertension, Renovascular; Imidazoles; Kidney; Male; Metabolic Syndrome; NADPH Oxidases; Obesity; Oxidative Stress; Rats; Rats, Zucker; Tetrazoles | 2007 |
Reverse-remodeling effects of angiotensin II type 1 receptor blocker in a canine atrial fibrillation model.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Atrial Fibrillation; Cardiac Electrophysiology; Disease Models, Animal; Dogs; Female; Heart Conduction System; Heart Rate; Imidazoles; Male; Myocardial Contraction; Myocardium; Secondary Prevention; Tetrazoles | 2007 |
Reduction of albuminuria by angiotensin receptor blocker beyond blood pressure lowering: evaluation in megsin/receptor for advanced glycation end products/inducible nitric oxide synthase triple transgenic diabetic nephropathy mouse model.
Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Diabetic Nephropathies; Disease Models, Animal; Imidazoles; Kidney; Male; Mice; Mice, Inbred ICR; Mice, Transgenic; Nitric Oxide Synthase Type II; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Serpins; Tetrazoles | 2008 |
Angiotensin II receptor antagonism reverts the selective cardiac BNP upregulation and secretion observed in myocarditis.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Atrial Natriuretic Factor; Blood Pressure; Cytokines; Disease Models, Animal; Imidazoles; Mycobacterium tuberculosis; Myocarditis; Myocardium; Natriuretic Peptide, Brain; Polymerase Chain Reaction; Protein Array Analysis; Rats; Rats, Inbred Lew; Receptor, Angiotensin, Type 1; RNA, Messenger; Tetrazoles; Up-Regulation | 2008 |
The collecting duct is the major source of prorenin in diabetes.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cell Division; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Hypertension, Renal; Imidazoles; Immunohistochemistry; Juxtaglomerular Apparatus; Kidney Tubules, Collecting; Microscopy, Fluorescence; Quinacrine; Rats; Rats, Wistar; Renin; Tetrazoles; Trypsin; Vasoconstrictor Agents | 2008 |
Effects of antihypertensive drugs and exercise training on insulin sensitivity in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Azetidinecarboxylic Acid; Blood Pressure; Combined Modality Therapy; Dihydropyridines; Disease Models, Animal; Drug Therapy, Combination; Heart Rate; Hypertension; Imidazoles; Insulin; Insulin Resistance; Male; Muscle, Skeletal; Physical Conditioning, Animal; Rats; Rats, Inbred SHR; Regression Analysis; Sympathetic Nervous System; Tetrazoles | 2008 |
Increased expression of angiotensin converting enzyme 2 in conjunction with reduction of neointima by angiotensin II type 1 receptor blockade.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Aorta, Abdominal; Blood Pressure; Carotid Arteries; Catheterization; Disease Models, Animal; Heart Rate; Hyperplasia; Hypertension; Imidazoles; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tetrazoles; Tunica Intima | 2008 |
Angiotensin II type 2 receptor antagonist reduces bleomycin-induced pulmonary fibrosis in mice.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Bleomycin; Blood Cell Count; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Hydroxyproline; Imidazoles; Macrophage Inflammatory Proteins; Male; Mice; Mice, Inbred ICR; Pulmonary Fibrosis; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Tumor Necrosis Factor-alpha; Vasoconstrictor Agents | 2008 |
Olmesartan ameliorates a dietary rat model of non-alcoholic steatohepatitis through its pleiotropic effects.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Choline Deficiency; Disease Models, Animal; Fatty Acids; Fatty Liver; Imidazoles; Insulin Resistance; Liver Cirrhosis, Experimental; Male; Methionine; Oxidative Stress; Rats; Rats, Long-Evans; RNA, Messenger; Sterol Regulatory Element Binding Protein 1; Tetrazoles; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2008 |
The effect of topical CS-088, an angiotensin AT1 receptor antagonist, on intraocular pressure and aqueous humor dynamics in rabbits.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Animals; Aqueous Humor; Chymotrypsin; Disease Models, Animal; Imidazoles; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Rabbits; Receptor, Angiotensin, Type 1; Tetrazoles; Timolol | 2001 |