Page last updated: 2024-09-04

olmesartan and Atherosclerosis

olmesartan has been researched along with Atherosclerosis in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (40.00)29.6817
2010's9 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jin, WD; Wang, XY; Wu, XM; Zhuang, RJ1
Ahn, CM; Choi, D; Hong, MK; Hong, SJ; Jang, Y; Kim, BK; Kim, CK; Kim, JS; Kim, SH; Ko, YG; Lee, JJ; Lee, OH; Lee, SG; Lee, SH; Lee, SJ; Oh, J; Park, S; Thuy, NVP1
Fukumoto, Y; Ito, K; Nawata, J; Onoue, N; Shimokawa, H; Sugimura, K; Tada, T; Wang, H; Zhulanqiqige, D1
David, S; Fliser, D; Haller, H; Kielstein, JT; Kümpers, P; Lukasz, A1
David, S; Fliser, D; Haller, H; Kielstein, JT; Lorenzen, JM; Neunhöffer, H1
Cheng, XW; Hayashi, T; Hu, L; Iguchi, A; Kuzuya, M; Murohara, T; Nakamura, K; Okumura, K; Sasaki, T; Sato, K; Song, H1
Fujita, M; Kishimoto, C; Kita, T; Murayama, T; Shimada, K; Yokode, M1
Isosaki, M; Kyotani, Y; Nakayama, H; Tomita, S; Uno, M; Yoshizumi, M; Zhao, J1
Hayashi, N; Iwamoto, Y; Oguro, R; Ohishi, M; Rakugi, H; Shiota, A; Takeda, M; Takeya, Y; Tatara, Y; Yamamoto, K1
Bando, YK; Cheng, XW; Hu, L; Inoue, A; Kuzuya, M; Murohara, T; Okumura, K; Sasaki, T; Shi, GP; Song, H1
Fukumoto, Y; Hosoya, M; Nakajima, S; Noda, K; Ohashi, J; Shimokawa, H1
Jin, D; Miyazaki, M; Muramatsu, M; Sakaguchi, M; Takai, S1
Fujita, K; Funahashi, T; Hibuse, T; Hiuge, A; Kihara, S; Kumada, M; Kurata, A; Kuriyama, H; Maeda, N; Nishizawa, H; Ohashi, K; Okada, T; Shimomura, I; Sonoda, M; Yasui, A1
Arishiro, K; Hanafusa, T; Hoshiga, M; Ishihara, T; Jin, D; Miyazaki, M; Negoro, N; Takai, S1
Havekes, LM; Jukema, JW; Kleemann, R; Kooistra, T; Princen, HM; van der Hoorn, JW1

Trials

1 trial(s) available for olmesartan and Atherosclerosis

ArticleYear
Circulating angiopoietin-2 in essential hypertension: relation to atherosclerosis, vascular inflammation, and treatment with olmesartan/pravastatin.
    Journal of hypertension, 2009, Volume: 27, Issue:8

    Topics: Adult; Aged; Angiopoietin-2; Angiotensin II Type 1 Receptor Blockers; Atherosclerosis; C-Reactive Protein; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Imidazoles; Male; Middle Aged; Pravastatin; Prospective Studies; Tetrazoles; Vasculitis

2009

Other Studies

14 other study(ies) available for olmesartan and Atherosclerosis

ArticleYear
Identification and characterization of the druggable kinase targets of olmesartan and its analogues from a systematic kinase-chemical interaction profile in atherosclerosis.
    Journal of molecular graphics & modelling, 2018, Volume: 80

    Topics: Atherosclerosis; Enzyme Activation; Imidazoles; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Protein Binding; Protein Kinase Inhibitors; Protein Kinases; Tetrazoles

2018
Synergistic protective effects of a statin and an angiotensin receptor blocker for initiation and progression of atherosclerosis.
    PloS one, 2019, Volume: 14, Issue:5

    Topics: Angiotensin Receptor Antagonists; Animals; Atherosclerosis; Cell Polarity; Disease Models, Animal; Drug Synergism; Imidazoles; Macrophages; Male; Mice; Rabbits; RAW 264.7 Cells; Rosuvastatin Calcium; Tetrazoles; Treatment Outcome

2019
Enhanced pulsatile pressure accelerates vascular smooth muscle migration: implications for atherogenesis of hypertension.
    Cardiovascular research, 2008, Dec-01, Volume: 80, Issue:3

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Atherosclerosis; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Calcium Signaling; Cell Movement; Cells, Cultured; Dihydropyridines; Disease Models, Animal; Equipment and Supplies; Estrenes; Hypertension; Imidazoles; Inositol 1,4,5-Trisphosphate Receptors; Macrocyclic Compounds; Muscle, Smooth, Vascular; Oxazoles; Pyrrolidinones; Rats; Rats, Wistar; Signal Transduction; Tetrazoles; Type C Phospholipases

2008
Angiotensin II receptor blocker and statins lower elevated levels of osteopontin in essential hypertension--results from the EUTOPIA trial.
    Atherosclerosis, 2010, Volume: 209, Issue:1

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Atherosclerosis; Biomarkers; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Imidazoles; Male; Middle Aged; Osteopontin; Pravastatin; Prospective Studies; Randomized Controlled Trials as Topic; Tetrazoles

2010
AT1 blockade attenuates atherosclerotic plaque destabilization accompanied by the suppression of cathepsin S activity in apoE-deficient mice.
    Atherosclerosis, 2010, Volume: 210, Issue:2

    Topics: Angiotensin I; Animal Feed; Animals; Apolipoproteins E; Atherosclerosis; Cathepsins; Collagen; Dietary Fats; Elastin; Imidazoles; Macrophages; Male; Mice; Oxidative Stress; Renin-Angiotensin System; Tetrazoles

2010
Olmesartan, a novel angiotensin II type 1 receptor antagonist, reduces severity of atherosclerosis in apolipoprotein E deficient mice associated with reducing superoxide production.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2011, Volume: 21, Issue:9

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Apolipoproteins E; Atherosclerosis; Biomarkers; Cells, Cultured; Chemokine CXCL2; Imidazoles; Interferon-gamma; Male; Mice; Mice, Inbred C57BL; Models, Animal; Oxidative Stress; Superoxides; Tetrazoles; Thioredoxins

2011
Olmesartan inhibits angiotensin II-Induced migration of vascular smooth muscle cells through Src and mitogen-activated protein kinase pathways.
    Journal of pharmacological sciences, 2010, Volume: 113, Issue:2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Atherosclerosis; Cell Movement; Cells, Cultured; Dose-Response Relationship, Drug; Imidazoles; JNK Mitogen-Activated Protein Kinases; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Signal Transduction; src-Family Kinases; Tetrazoles

2010
The counterregulating role of ACE2 and ACE2-mediated angiotensin 1-7 signaling against angiotensin II stimulation in vascular cells.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2010, Volume: 33, Issue:11

    Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Atherosclerosis; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Enzyme Inhibitors; Humans; Imidazoles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Monocytes; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Receptors, G-Protein-Coupled; Tetrazoles

2010
Angiotensin type 1 receptor blocker reduces intimal neovascularization and plaque growth in apolipoprotein E-deficient mice.
    Hypertension (Dallas, Tex. : 1979), 2011, Volume: 57, Issue:5

    Topics: Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Apolipoproteins E; Atherosclerosis; Dietary Fats; Enzyme-Linked Immunosorbent Assay; Imidazoles; Male; Matrix Metalloproteinase 2; Mice; Mice, Knockout; Neovascularization, Pathologic; Random Allocation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Tetrazoles; Toll-Like Receptor 2; Toll-Like Receptor 4; Tunica Intima

2011
Anti-atherogenic effects of the combination therapy with olmesartan and azelnidipine in diabetic apolipoprotein E-deficient mice.
    The Tohoku journal of experimental medicine, 2012, Volume: 228, Issue:4

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Apolipoproteins E; Atherosclerosis; Azetidinecarboxylic Acid; Azo Compounds; Blood Pressure; Body Weight; Calcium Channel Blockers; Coronary Vessels; Diabetes Mellitus, Experimental; Dihydropyridines; Drug Therapy, Combination; Imidazoles; Macrophages; Male; Mice; Mice, Inbred C57BL; Models, Biological; Myocytes, Cardiac; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Systole; Tetrazoles

2012
The regressive effect of an angiotensin II receptor blocker on formed fatty streaks in monkeys fed a high-cholesterol diet.
    Journal of hypertension, 2005, Volume: 23, Issue:10

    Topics: Acetylcholine; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Atherosclerosis; Carotid Arteries; Chemokine CCL2; Cholesterol; Cholesterol, Dietary; Dose-Response Relationship, Drug; Hyperplasia; Imidazoles; In Vitro Techniques; Lipids; Macaca fascicularis; Male; Peptidyl-Dipeptidase A; Random Allocation; Renin; Reproducibility of Results; Tetrazoles; Time Factors; Tunica Intima; Ultrasonography, Interventional; Vasodilation; Vasodilator Agents

2005
Blockade of Angiotensin II type-1 receptor reduces oxidative stress in adipose tissue and ameliorates adipocytokine dysregulation.
    Kidney international, 2006, Volume: 70, Issue:10

    Topics: Adiponectin; Adipose Tissue; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Atherosclerosis; Cells, Cultured; Female; Gene Expression Regulation; Imidazoles; Kidney Diseases; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Obesity; Oxidative Stress; Plasminogen Activator Inhibitor 1; Reactive Oxygen Species; RNA, Messenger; Serum Amyloid A Protein; Signal Transduction; Tetrazoles; Tumor Necrosis Factor-alpha

2006
Angiotensin receptor-1 blocker inhibits atherosclerotic changes and endothelial disruption of the aortic valve in hypercholesterolemic rabbits.
    Journal of the American College of Cardiology, 2007, Apr-03, Volume: 49, Issue:13

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Aortic Valve; Atherosclerosis; Endothelium, Vascular; Hypercholesterolemia; Imidazoles; Male; Rabbits; Tetrazoles

2007
Olmesartan and pravastatin additively reduce development of atherosclerosis in APOE*3Leiden transgenic mice.
    Journal of hypertension, 2007, Volume: 25, Issue:12

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Apolipoprotein E3; Atherosclerosis; Blood Pressure; Collagen; Diet, Atherogenic; Drug Synergism; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imidazoles; Inflammation; Lipids; Macrophages; Mice; Mice, Transgenic; Monocytes; Muscle, Smooth, Vascular; Pravastatin; Recombinant Proteins; Serum Amyloid A Protein; T-Lymphocytes; Tetrazoles

2007