olivomycins and Disease-Models--Animal

Development and regression of experimental atherosclerosis in rabbits is an expressed age-related phenomenon, showing the increase in occurrence and pronouncement of atherosclerotic process with age. A new approach to the disease treatment by means of olivomycin is described. It has shown that while influencing considerably the protein biosynthesis of experimental animal, one can accelerate the regression of atherosclerosis by means of olivomycin and reduce protein and lipid metabolism indicators characterizing the disease development.

Topics: Aging; Animals; Apolipoproteins; Arteriosclerosis; Disease Models, Animal; Drug Evaluation, Preclinical; Lipids; Olivomycins; Protein Synthesis Inhibitors; Rabbits; Remission, Spontaneous