oleylamide and Potassium-Deficiency

oleylamide has been researched along with Potassium-Deficiency* in 1 studies

Other Studies

1 other study(ies) available for oleylamide and Potassium-Deficiency

Article	Year
Oleamide attenuates apoptotic death in cultured rat cerebellar granule neurons. Neuroscience letters, 2002, Aug-09, Volume: 328, Issue:2 The effect of oleamide on apoptosis was investigated by using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide reduction assay, DNA staining assay with propidium iodide and caspase-3 activity analyses. The present results showed that oleamide significantly attenuated the cell death and nuclear condensation of cultured rat cerebellar granule neurons induced by K(+) deprivation in a dose-dependent manner. The oleamide actions were well parallel with the attenuation of caspase-3 activity in the process of apoptotic death. Moreover, neither elaidic acid nor stearic acid, two fatty acids structurally related to oleamide without the Delta(9)-cis double bond, had similar effects on the cell death, suggesting the selectively structural features of oleamide required for this action. These data provided the first evidence of a protective effect of oleamide against apoptosis in a structurally specific manner. Topics: Animals; Animals, Newborn; Apoptosis; Caspase 3; Caspase Inhibitors; Caspases; Cell Membrane; Cell Nucleus; Cell Survival; Cells, Cultured; Cerebellar Cortex; Dose-Response Relationship, Drug; Neurons; Neuroprotective Agents; Oleic Acids; Potassium; Potassium Deficiency; Rats; Rats, Wistar	2002

Article

Year

Oleamide attenuates apoptotic death in cultured rat cerebellar granule neurons.

Neuroscience letters, 2002, Aug-09, Volume: 328, Issue:2

The effect of oleamide on apoptosis was investigated by using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide reduction assay, DNA staining assay with propidium iodide and caspase-3 activity analyses. The present results showed that oleamide significantly attenuated the cell death and nuclear condensation of cultured rat cerebellar granule neurons induced by K(+) deprivation in a dose-dependent manner. The oleamide actions were well parallel with the attenuation of caspase-3 activity in the process of apoptotic death. Moreover, neither elaidic acid nor stearic acid, two fatty acids structurally related to oleamide without the Delta(9)-cis double bond, had similar effects on the cell death, suggesting the selectively structural features of oleamide required for this action. These data provided the first evidence of a protective effect of oleamide against apoptosis in a structurally specific manner.

Topics: Animals; Animals, Newborn; Apoptosis; Caspase 3; Caspase Inhibitors; Caspases; Cell Membrane; Cell Nucleus; Cell Survival; Cells, Cultured; Cerebellar Cortex; Dose-Response Relationship, Drug; Neurons; Neuroprotective Agents; Oleic Acids; Potassium; Potassium Deficiency; Rats; Rats, Wistar

2002