oleoylanilide has been researched along with Pain* in 1 studies
1 other study(ies) available for oleoylanilide and Pain
Article | Year |
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Neurotransmitter changes in cerebrospinal fluid in the Spanish toxic oil syndrome: human clinical findings and experimental results in mice.
Patients with Spanish Toxic Oil Syndrome (TOS) complaining of neuromuscular symptoms had increased levels of homovanillic acid and 5-hydroxyindoleacetic acid (5-HIAA) in cerebrospinal fluid. Severity of pain and muscle cramps correlated with the magnitude of increment in levels of monoamine metabolites. Mice treated with oleyl anilide, a putative toxic compound found in some stocks of the toxic rapeseed oil, did not present clinical or anatomical findings compatible with TOS. However, biochemical studies in these mice revealed a depletion of serotonin and an elevation of 5-HIAA levels. Our findings suggest that the unidentified toxic agent of the TOS and oleyl anilide induce pharmacological changes in monoamine neurons of the brain. Topics: Anilides; Animals; Brain Chemistry; Brassica; Catecholamines; Disease Models, Animal; Foodborne Diseases; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Mice; Oils; Oleic Acids; Pain | 1986 |