oleoyl-estrone and Growth-Disorders

oleoyl-estrone has been researched along with Growth-Disorders* in 1 studies

Other Studies

1 other study(ies) available for oleoyl-estrone and Growth-Disorders

Article	Year
The administration of oleoyl-estrone to lactating dams induces selective changes in the normal growth pattern of their pups. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2007, Volume: 39, Issue:8 To determine the effects of oleoyl-estrone treatment on the lactating dams and on the growth pattern of developing rats, female Wistar rats were randomly divided into two groups after delivery. One group received a daily gavage of 0.2 mL sunflower oil containing 10 micromol oleoyl-estrone/kg (treated group) and the other received a daily intragastric gavage of 0.2 mL sunflower oil (control group). Treatment was carried out during the first 15 days of lactation. Dams were killed on days 1, 15 or 20 after delivery and pups were sacrificed on days 1, 15, 20 or 30. Treated dams showed a transient decrease in food intake, significant lower lipid content than control dams, with a parallel maintenance of protein content and no appreciative changes in plasmatic parameters. However, a significant increase in brown adipose tissue mass was detected in treated group. Pups from treated dams showed a decrease in their growth rate that was reflected in the lower adipose tissue mass in different locations, except in the case of brown adipose tissue and, that continued after cessation of treatment. Thus, treatment affects dams in a selective way that does not coincide with a simple food restriction model. Topics: Adipose Tissue, White; Animals; Animals, Newborn; Anti-Obesity Agents; Body Composition; Body Weight; Eating; Estrone; Feeding Behavior; Female; Growth and Development; Growth Disorders; Lactation; Male; Oleic Acids; Rats; Rats, Wistar	2007

Article

Year

The administration of oleoyl-estrone to lactating dams induces selective changes in the normal growth pattern of their pups.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2007, Volume: 39, Issue:8

To determine the effects of oleoyl-estrone treatment on the lactating dams and on the growth pattern of developing rats, female Wistar rats were randomly divided into two groups after delivery. One group received a daily gavage of 0.2 mL sunflower oil containing 10 micromol oleoyl-estrone/kg (treated group) and the other received a daily intragastric gavage of 0.2 mL sunflower oil (control group). Treatment was carried out during the first 15 days of lactation. Dams were killed on days 1, 15 or 20 after delivery and pups were sacrificed on days 1, 15, 20 or 30. Treated dams showed a transient decrease in food intake, significant lower lipid content than control dams, with a parallel maintenance of protein content and no appreciative changes in plasmatic parameters. However, a significant increase in brown adipose tissue mass was detected in treated group. Pups from treated dams showed a decrease in their growth rate that was reflected in the lower adipose tissue mass in different locations, except in the case of brown adipose tissue and, that continued after cessation of treatment. Thus, treatment affects dams in a selective way that does not coincide with a simple food restriction model.

Topics: Adipose Tissue, White; Animals; Animals, Newborn; Anti-Obesity Agents; Body Composition; Body Weight; Eating; Estrone; Feeding Behavior; Female; Growth and Development; Growth Disorders; Lactation; Male; Oleic Acids; Rats; Rats, Wistar

2007