oleoyl-coenzyme-a and Brain-Ischemia

oleoyl-coenzyme-a has been researched along with Brain-Ischemia* in 1 studies

Other Studies

1 other study(ies) available for oleoyl-coenzyme-a and Brain-Ischemia

ArticleYear
Metabolism of oleoyl-CoA in rat brain synaptosomes: effects of calcium and post-decapitative ischemia.
    Neurochemical research, 1981, Volume: 6, Issue:11

    The hydrolysis of acyl-CoA by acyl-CoA hydrolase (EC 3.1.2.2.) in brain synaptosomes was inhibited by calcium. This inhibition was partly due to interaction of Ca2+ with the acyl-CoA, which was present in the soluble form, and partly due to complex formation among acyl-CoA, Ca2+ and membrane phospholipids. The inhibition of acyl-CoA hydrolase activity, as well as the complex formation, could be reversed if incubation was carried out in the presence of Ca2+ chelating agents. Synaptosomes isolated from brain samples after 1 min of postdecapitative treatment showed a decrease in oleoyl-CoA hydrolase activity. The physiological implication of acyl-CoA metabolism in relation to synaptic function is discussed.

    Topics: Acyl Coenzyme A; Animals; Brain Ischemia; Calcium; Cerebral Cortex; Intracellular Membranes; Palmitoyl-CoA Hydrolase; Rats; Rats, Inbred Strains; Synaptosomes

1981