oleic acid has been researched along with Fatty Liver in 109 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (4.59) | 18.7374 |
| 1990's | 3 (2.75) | 18.2507 |
| 2000's | 15 (13.76) | 29.6817 |
| 2010's | 74 (67.89) | 24.3611 |
| 2020's | 12 (11.01) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, KD; Blaner, WS; Chen, P; Cioffi, CL; Conlon, MP; Freeman, EE; Johnson, G; Kitchen, DB; Martin, WH; Pearson, PG; Petrukhin, K; Racz, B; Varadi, A; Zhu, L | 1 |
| Al-Akl, NS; Arredouani, A; Errafii, K; Khalifa, O | 1 |
| Baddela, VS; Plinski, C; Sharma, A; Vanselow, J | 1 |
| Chen, YF; Lin, XL; Liu, XT; Liu, XY; Lv, XT; Wang, GE; Wang, RH; Yang, F | 1 |
| Kim, HA; Kim, HJ; Lee, YH; You, M | 1 |
| Cheng, H; Hu, Y; Li, L; Liu, Y; Sairijima, T; Song, H; Sun, P; Wang, L; Xing, X; Yang, R; Zhang, J; Zhang, Q | 1 |
| Feng, B; Li, H; Su, Z; Tang, L; Ye, Z; Zheng, G; Zhu, Y | 1 |
| Gu, X; Hu, Y; Shen, L; Wang, C; Xiong, X; Zekrumah, M; Zhang, D; Zou, X | 1 |
| Aljohani, A; Bonneville, A; Burhans, M; Guo, C; Jeffery, J; Khan, MI; Lewis, SA; Mukhtar, H; Ntambi, JM; O'Neill, L; Syed, DN | 1 |
| Chen, Y; Dong, Z; Huang, B; Li, M; Li, R; Liu, R; Xia, C; Xu, C; Yang, W | 1 |
| Acharya, V; Gopal Reddy, MR; Jeyakumar, SM; Kumar, MS; Putcha, UK; Venkata, SM | 1 |
| Chen, C; Gong, W; Huo, J; Jia, X; Li, Y; Ma, Y; Qin, W; Wang, J; Yang, Z; Zhang, H; Zhuo, Q | 1 |
| Ku, WW; Pande, P; Zhong, XB | 1 |
| Ding, H; Feng, S; Hao, N; Jiang, Q; Li, Y; Liang, Y; Liu, L; Loor, JJ; Ma, N; Wang, X; Wu, J; Zou, S | 1 |
| Baixeras, E; Ciccocioppo, R; Decara, J; Gavito, AL; Hernandez-Folgado, L; Jagerovic, N; Rodríguez de Fonseca, F; Soverchia, L; Tovar, R; Vargas, A | 1 |
| Chen, Z; Ding, J; Dong, Q; Hu, N; Tie, F; Wang, H | 1 |
| Chen-Liaw, AY; Gomez, G; Hammel, G | 1 |
| Berndt, N; Borlak, J; Damm, G; Eleftheriadou, D; Holzhütter, HG; Schulz, T; Seehofer, D; Wallstab, C | 1 |
| Feng, H; Han, L; Li, Z; Liu, G; Lv, H; Shen, B; Tian, Y; Wu, L; Zhang, Q | 1 |
| Bian, J; Chen, T; Cheng, X; Ji, X; Yan, D; Yin, W | 1 |
| Chen, JT; Chen, KY; Chen, YP; Ho, BY; Hsieh, MC; Hsu, AC; Hsu, RY; Lin, JA; Shen, TL; Tai, YT; Wang, GH; Wu, HT; Yao, HY | 1 |
| Cao, LP; Ding, W; Du, J; Jia, R; Xu, P; Yin, G | 1 |
| Gong, R; Liu, F; Lv, X | 1 |
| Huang, Z; Li, H; Liu, W; Liu, Y; Shi, P; Wang, J; Wang, Q; Wang, S | 1 |
| Chen, JW; Ho, CT; Kong, ZL; Lai, CS; Lo, CY; Tsai, ML | 1 |
| Chen, W; Hu, D; Ke, H; Li, Y; Su, H; Xie, L; Zheng, X | 1 |
| Chen, L; Deng, X; Hu, J; Li, X; Qiu, Z; Sheng, L; Zhang, C; Zheng, G; Zhou, J | 1 |
| Jung, DY; Jung, MH; Kim, JH; Nagappan, A | 1 |
| Gao, JX; Li, XJ; Li, YS; Tang, HB; Zhang, W | 1 |
| Bandy, B; Omidian, K; Rafiei, H | 1 |
| Bian, J; Gu, J; Liu, X; Liu, Z; Luo, T; Wang, J; Yang, L; Yang, W; Yuan, Y; Zhang, H; Zou, H | 1 |
| Bian, Y; Dong, L; Hu, X; Ju, J; Li, J; Li, X; Liang, H; Wang, N; Yang, B; Zhang, Y | 1 |
| Brown, MV; Cheatham, B; Compton, SA; Lawton, KA; Milburn, MV | 1 |
| Coleman, R; Gamliel-Lazarovich, A; Keidar, S; Raz-Pasteur, A | 1 |
| Bernal, CA; González, MA; Lasa, A; Portillo, MP; Saín, J; Scalerandi, MV | 1 |
| Abdirad, A; Ahmadian, S; Ghaffari, SM; Hassanzadeh, G; Khaghani, S; Nowrouzi, A; Vardasbi, S; Ziamajidi, N | 1 |
| Chang, CJ; Hung, HC; Lu, FH; Ou, HY; Su, YC; Wu, CL; Wu, HT; Wu, JS; Yang, YC | 1 |
| Chen, D; Ding, W; Li, N; Liu, D; Liu, K; Lou, J; Wang, A; Wen, T; Xu, B; Yin, J; Zhang, C | 1 |
| Yang, H; Zhang, L; Zhao, JJ; Zhao, LF | 1 |
| Huang, HP; Liao, CC; Ou, TT; Wang, CJ | 1 |
| Jiang, Z; Kang, YJ; Lv, ZL; Wang, C; Wang, PL; Xiang, TX | 1 |
| Aguilar-Pelaez, K; Danielsen, PH; Folkmann, JK; Jespersen, LF; Loft, S; Møller, P; Roursgaard, M; Vesterdal, LK | 1 |
| Chen, XF; Gu, LY; Lv, L; Mei, ZC; Qiu, LW | 1 |
| Alisi, A; Ceccarelli, S; Crudele, A; De Stefanis, C; Gaspari, S; Gnani, D; Locatelli, F; Marquez, VE; Nobili, V; Rota, R; Vella, S | 1 |
| Canesi, L; Compalati, AD; Damonte, G; Gallo, G; Goglia, F; Grasselli, E; Salis, A; Vergani, L; Voci, A | 1 |
| Anthérieu, S; Claude, N; de la Moureyre-Spire, C; Guillouzo, A; Rogue, A; Umbdenstock, T; Vluggens, A; Weaver, RJ | 1 |
| Holm, C; Jones, HA; Motlagh, MK; Stenkula, KG; Winberg, ME | 1 |
| Deng, H; Luo, Y; Qin, S; Tang, W; Yin, J; Zeng, L; Zhou, B | 1 |
| Cho, KH; Kim, JM; Park, KH | 1 |
| Chen, XF; Gu, LY; Lü, L; Mei, ZC; Qiu, LW | 1 |
| Cha, BS; Ham, DS; Kang, ES; Kim, JW; Lee, BW; Lee, HC; Lee, YH; Song, YM | 1 |
| Beard, MR; George, J; Helbig, KJ; McCartney, EM; Tse, E; Van der Hoek, K; Van der Hoek, M | 1 |
| Hwang, HC; Kang, DG; Kang, OH; Kim, SB; Kwon, DY; Lee, HS; Lee, YM; Mun, SH; Seo, YS | 1 |
| Chan, KC; Chang, XZ; Lee, YJ; Wang, CJ; Wu, CH; Yang, MY | 1 |
| Huo, Y; Ji, B; Wang, D; Wang, Y; Zhao, L | 1 |
| Dou, QL; Wang, Z; Wei, YY; Yan, D | 1 |
| Huangfu, CS; Ji, AL; Li, YZ; Liu, B; Zhang, YJ; Zheng, NR | 1 |
| Cui, H; Geng, T; Gong, D; Li, F; Liu, L; Montgomery, S; Wang, Q; Xia, L; Yang, B; Zhao, X | 1 |
| Chen, Z; Han, T; Jin, J; Wang, J; Xie, C; Xu, X; Zhan, W; Zhang, C | 1 |
| Chen, S; Cheng, J; Deng, L; Feng, GS; Kang, Y; Li, Y; Liu, W; Lu, Z; Sun, Y; Tao, J; Tian, Y; Zhao, Y; Zhong, Y | 1 |
| Baldini, F; Grasselli, E; Grattagliano, I; Portincasa, P; Vecchione, G; Vergani, L; Voci, A; Wang, DQ | 1 |
| Gupta, S; Patel, TP; Rawal, K; Soni, S | 1 |
| Fang, Z; Hu, L; Huang, Z; Shi, P; Wang, J; Wang, S; Zhang, X | 1 |
| Chen, YW; Ding, YN; Dong, Y; Fan, JG; Li, BH; Wang, J; Zhou, D | 1 |
| An, HT; Kang, M; Kim, J; Ko, J | 1 |
| Anty, R; Bertola, A; Bonnafous, S; Clément, K; Dahman, M; Deveaux, V; Frayn, KN; Gual, P; Gugenheim, J; Huet, PM; Le Marchand-Brustel, Y; Lotersztajn, S; McQuaid, SE; Rousseau, D; Tordjman, J; Tran, A; Wakkach, A | 1 |
| Anzivino, C; Ballestri, S; Banni, S; Bertolotti, M; Carulli, L; Carulli, N; Fantoni, LI; Lonardo, A; Loria, P; Marra, F; Odoardi, MR; Pinetti, A; Ricchi, M | 1 |
| Elias, M; Green, RM; Koppe, SW; Moseley, RH | 1 |
| Chang, SP; Chen, YH; Hu, ML; Yang, CM | 1 |
| Larter, CZ; Nolan, CJ | 1 |
| Cho, HK; Kwon, YH; Lee, JY | 1 |
| Chen, SH; Li, WP; Li, YM; Liu, J | 1 |
| Connor, EE; Delmonte, P; Erdman, RA; Kadegowda, AK; Piperova, LS; Sampugna, J; Teter, BB | 1 |
| Akazawa, Y; Bronk, SF; Cazanave, SC; Elmi, NA; Gores, GJ; Mott, JL | 1 |
| Berk, PD; Ge, F; Hu, C; Lobdell, H; Zhou, S | 1 |
| De Gottardi, A; Hadengue, A; Ravier-Dall'Antonia, F; Spahr, L | 1 |
| Han, C; Kang, B; Li, L; Lu, L; Lv, J; Pan, Z; Tang, H; Wang, J; Xu, F; Zhou, Z | 1 |
| Balabaud, C; Bérard, AM; Bioulac-Sage, P; Chevet, E; Costet, P; De Ledinghen, V; Higa-Nishiyama, A; Lepreux, S; Mulot, A; Nurden, AT; Ripoche, J; Rosenbaum, J; Villeneuve, J | 1 |
| Canesi, L; Cioffi, F; De Matteis, R; Fugassa, E; Gallo, G; Goglia, F; Grasselli, E; Vergani, L; Voci, A | 1 |
| Aleman, JO; Hansen, ME; Kelleher, JK; Noguchi, Y; Stephanopoulos, G; Young, JD | 1 |
| Anthérieu, S; Fromenty, B; Guillouzo, A; Robin, MA; Rogue, A | 1 |
| Amankwa-Sakyi, M; Flynn, TJ; Garcia, MC | 1 |
| Chen, S; Du, Y; Guo, F; Li, H; Meng, Q; Wang, C; Xiao, F; Yu, J | 1 |
| Cai, S; Chu, L; Gao, F; Ji, B; Jia, G; Liu, J; Liu, Y; Wang, A; Wei, Y; Wu, W; Xie, L; Zhang, D; Zhou, F | 1 |
| Bockus, A; Copple, BL; Ding, WX; Kassel, KM; Luyendyk, JP; Manley, S; Mei, S; Ni, HM | 1 |
| Chen, CT; Cheng, JT; Chi, CW; Chung, HH; Wu, HT; Yang, PS; Yeh, CH | 1 |
| Ji, B; Li, M; Liu, Y; Lv, Y; Mao, T; Tang, M; Wang, D; Wei, Y; Wu, W; Zhang, D; Zhou, F | 1 |
| Brindley, DN; Dyck, JR; Kienesberger, PC; Kok, BP | 1 |
| Chavez-Tapia, NC; Rosso, N; Tiribelli, C | 1 |
| Barooah, V; Nandakumar, KS; Patki, PS; Sandeep Varma, R; Sharath Kumar, LM; Vidyashankar, S | 1 |
| Aransay, AM; Aspichueta, P; Banasik, K; Buque, X; Caballeria, J; Castro, A; Clement, K; Echevarria-Uraga, JJ; Garcia-Monzon, C; Garcia-Rodriguez, JL; Gonzalez-Lahera, A; Gual, P; Hansen, T; Joergensen, T; Justesen, JM; Lauritzen, T; Le Marchand-Brustel, Y; Lozano, JJ; Martin-Duce, A; Martinez-Arranz, I; Martinez-Chantar, ML; Mato, JM; Mendibil, I; Pedersen, O; Regueiro, MM; Rodriguez-Ezpeleta, N; Schlangen, KA; Tordjman, J; Tran, A; Vazquez-Chantada, M; Veyrie, N; Witte, DR | 1 |
| Patki, PS; Sandeep Varma, R; Vidyashankar, S | 1 |
| Cook, CR; Lyman, RL; Williams, MA | 1 |
| ALFIN-SLATER, RB; BERNICK, S; MORIN, RJ; SHIMMA, Y | 1 |
| LENAZ, G; SECHI, AM; VIVIANI, R | 1 |
| Krause, RF | 1 |
| Cornatzer, WE; Glende, EA | 1 |
| Bronk, SF; Burgart, LJ; Canbay, A; Feldstein, AE; Gores, GJ; Guicciardi, ME; Rydzewski, R; Werneburg, NW | 1 |
| Castell, JV; Donato, MT; Gómez-Lechón, MJ; Jiménez, N; Martínez-Romero, A; O'Connor, JE | 1 |
| Barreyro, FJ; Bronk, SF; Gores, GJ; Isomoto, H; Malhi, H | 1 |
| De Gottardi, A; Foti, M; Hadengue, A; Moukil, M; Pazienza, V; Pugnale, P; Ravier-Dall'Antonia, F; Sgroi, A; Vinciguerra, M | 1 |
| Chung, KW; Chung, WJ; Han, MS; Hwang, JS; Kim, S; Kwon, CH; Lee, JH; Lee, KW; Lee, MS; Park, CK; Park, SY; Shinzawa, K; Song, DK; Tsujimoto, Y; Yan, JJ | 1 |
| Chu, K; Flowers, MT; Liu, X; Miyazaki, M; Ntambi, JM; Otzelberger, C; Sampath, H | 1 |
| Gayet, C; Ginsberg, HN; Ota, T | 1 |
| Mukherjee, KD; Richter, KD; Weber, N | 1 |
| Horiuchi, M; Inoue, F; Kinugasa, A; Kizaki, Z; Kodo, N; Nakajima, T; Saheki, T; Sawada, T; Yamanaka, H | 1 |
| Kruip, TA; Meijer, GA; Rukkwamsuk, T; Wensing, T | 1 |
| Geelen, MJ; Kruip, TA; Rukkwamsuk, T; Wensing, T | 1 |
| Buckley, MC; Fried, SK; Kral, JG; Weber, RV | 1 |
109 other study(ies) available for oleic acid and Fatty Liver
| Article | Year |
|---|---|
Design, Synthesis, and Preclinical Efficacy of Novel Nonretinoid Antagonists of Retinol-Binding Protein 4 in the Mouse Model of Hepatic Steatosis.
Topics: Animals; Chemistry Techniques, Synthetic; Disease Models, Animal; Drug Design; Fatty Liver; Male; Mice; Piperidines; Rats; Retinol-Binding Proteins, Plasma; Tissue Distribution | 2019 |
Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway.
Topics: Exenatide; Fatty Acid-Binding Proteins; Fatty Liver; Glucagon-Like Peptide-1 Receptor; Hep G2 Cells; Hepatocyte Nuclear Factor 3-alpha; Humans; In Vitro Techniques; Lipid Metabolism; Lipogenesis; Models, Biological; Oleic Acid; Protective Agents; Sterol Regulatory Element Binding Protein 1; Transcription Factor 4; Wnt Signaling Pathway | 2022 |
Palmitic acid protects granulosa cells from oleic acid induced steatosis and rescues progesterone production via cAMP dependent mechanism.
Topics: Fatty Liver; Female; Granulosa Cells; Humans; Oleic Acid; Palmitic Acid; Progesterone | 2022 |
Biochanin A ameliorated oleate-induced steatosis in HepG2 cells by activating the SIRT3/AMPK/ULK-1 signaling pathway.
Topics: AMP-Activated Protein Kinases; Fatty Liver; Hep G2 Cells; Humans; Oleic Acid; Signal Transduction; Sirtuin 3 | 2022 |
Red Pepper Seeds Inhibit Hepatic Lipid Accumulation by Inducing Autophagy via AMPK Activation.
Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Capsicum; Diet, High-Fat; Fatty Liver; Glucose; Lipid Metabolism; Liver; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Oleic Acid; Plant Extracts; Seeds; TOR Serine-Threonine Kinases | 2022 |
Oleic acid-induced steatosis model establishment in LMH cells and its effect on lipid metabolism.
Topics: Animals; Chickens; Fatty Acids; Fatty Liver; Lipid Metabolism; Liver; Male; Oleic Acid | 2023 |
Qidan Tiaozhi capsule attenuates metabolic syndrome via activating AMPK/PINK1-Parkin-mediated mitophagy.
Topics: AMP-Activated Protein Kinases; Animals; Cholesterol, LDL; Drugs, Chinese Herbal; Fatty Liver; Insulin Resistance; Metabolic Syndrome; Mice; Mitophagy; Molecular Docking Simulation; Oleic Acid; Phosphatidylinositol 3-Kinases; Reactive Oxygen Species; Triglycerides; Ubiquitin-Protein Ligases | 2023 |
Optimization of betacyanins from agricultural by-products using pressurized hot water extraction for antioxidant and in vitro oleic acid-induced steatohepatitis inhibitory activity.
Topics: Alanine Transaminase; Antioxidants; Aspartate Aminotransferases; Betacyanins; Chromatography, High Pressure Liquid; Fatty Liver; Hep G2 Cells; Hot Temperature; Humans; Mass Spectrometry; Oleic Acid; Plant Extracts; Water | 2019 |
Hepatic stearoyl CoA desaturase 1 deficiency increases glucose uptake in adipose tissue partially through the PGC-1α-FGF21 axis in mice.
Topics: Adiponectin; Adipose Tissue; Adiposity; Animals; Carbohydrate Metabolism; Diet; Fatty Acids, Monounsaturated; Fatty Liver; Fibroblast Growth Factors; Glucose; Insulin; Lipid Metabolism; Lipogenesis; Liver; Male; Mice; Mice, Knockout; Oleic Acid; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Positron Emission Tomography Computed Tomography; Stearoyl-CoA Desaturase | 2019 |
Effects of different fatty acids on BRL3A rat liver cell damage.
Topics: Acetyl-CoA Carboxylase; alpha-Linolenic Acid; Animals; Cells, Cultured; Endoplasmic Reticulum Stress; Fatty Acid Synthases; Fatty Acids; Fatty Liver; Hepatocytes; Humans; Linoleic Acid; Lipid Metabolism; Lipids; Lipogenesis; Lipoproteins, VLDL; Liver; Oleic Acid; Oxidative Stress; Palmitic Acid; Rats; Stearic Acids | 2020 |
Vitamin A deficiency increases the oleic acid (C18:1) levels in the kidney of high fructose diet-fed rats.
Topics: Animals; Diet; Fatty Acids, Monounsaturated; Fatty Liver; Fructose; Gene Expression Regulation, Enzymologic; Humans; Kidney; Oleic Acid; Rats; Stearoyl-CoA Desaturase; Vitamin A; Vitamin A Deficiency | 2019 |
[Steatosis and inflammation of L02 hepatocytes induced by sodium oleate].
Topics: Fatty Liver; Hepatocytes; Humans; Inflammation; NF-kappa B; Oleic Acid | 2020 |
Histone Methyltransferase G9a Regulates Expression of Nuclear Receptors and Cytochrome P450 Enzymes in HepaRG Cells at Basal Level and in Fatty Acid Induced Steatosis.
Topics: Cell Line, Tumor; Culture Media; Cytochrome P-450 Enzyme System; DNA Methylation; Epigenesis, Genetic; Fatty Liver; Gene Expression Regulation; Gene Knockdown Techniques; Hepatocytes; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Histones; Humans; Liver; Oleic Acid; Palmitic Acid; Polymorphism, Single Nucleotide; Receptors, Cytoplasmic and Nuclear | 2020 |
Sirtuin 1 is involved in oleic acid-induced calf hepatocyte steatosis via alterations in lipid metabolism-related proteins.
Topics: Animals; Cattle; Fatty Liver; Female; Hepatocytes; Lipid Metabolism; Liver; Oleic Acid; Sirtuin 1 | 2021 |
Palmitoleoylethanolamide Is an Efficient Anti-Obesity Endogenous Compound: Comparison with Oleylethanolamide in Diet-Induced Obesity.
Topics: Animals; Body Weight; Cytokines; Diet; Endocannabinoids; Ethanolamines; Fatty Acids; Fatty Acids, Monounsaturated; Fatty Liver; Humans; Insulin Resistance; Lipogenesis; Liver; Male; Obesity; Oleic Acid; Oleic Acids; Rats; Rats, Sprague-Dawley | 2021 |
Kaempferol and Kaempferide Attenuate Oleic Acid-Induced Lipid Accumulation and Oxidative Stress in HepG2 Cells.
Topics: Carcinoma, Hepatocellular; Fatty Liver; Hep G2 Cells; Humans; Kaempferols; Lipogenesis; Liver Neoplasms; Oleic Acid; Oxidative Stress; Signal Transduction | 2021 |
Inhibition of exendin-4-induced steatosis by protein kinase A in cultured HepG2 human hepatoma cells.
Topics: Carcinoma, Hepatocellular; Cell Survival; Cyclic AMP-Dependent Protein Kinases; Exenatide; Fatty Liver; Glucagon-Like Peptide 1; Hep G2 Cells; Hepatocytes; Humans; Isoquinolines; Linoleic Acid; Lipogenesis; Liver Neoplasms; Oleic Acid; Pancreas; Peptides; Sulfonamides; Triglycerides; Venoms | 2017 |
A unifying mathematical model of lipid droplet metabolism reveals key molecular players in the development of hepatic steatosis.
Topics: Cell Line, Tumor; Cholesterol Esters; Diacylglycerol O-Acyltransferase; Fatty Liver; Gene Expression Regulation; Hepatocytes; Humans; Lipase; Lipid Droplets; Lipid Metabolism; Models, Biological; Models, Statistical; Oleic Acid; Palmitic Acid; Primary Cell Culture; Triglycerides | 2017 |
Magnolol Alleviates Inflammatory Responses and Lipid Accumulation by AMP-Activated Protein Kinase-Dependent Peroxisome Proliferator-Activated Receptor α Activation.
Topics: AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Biphenyl Compounds; Fatty Liver; Hep G2 Cells; Humans; Hyperlipidemias; Lignans; Lipid Metabolism; Male; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; NF-kappa B; Oleic Acid; PPAR alpha | 2018 |
miR-1224-5p Enhances Hepatic Lipogenesis by Targeting Adenosine Monophosphate-Activated Protein Kinase α1 in Male Mice.
Topics: AMP-Activated Protein Kinases; Animals; Diet, High-Fat; Down-Regulation; Fatty Liver; Gene Expression Regulation; Gene Knockdown Techniques; Hep G2 Cells; Hepatocytes; Humans; In Vitro Techniques; Lipogenesis; Liver; Male; Mice; Mice, Obese; MicroRNAs; Oleic Acid; Palmitic Acid; Triglycerides | 2018 |
Arctigenin protects against steatosis in WRL68 hepatocytes through activation of phosphoinositide 3-kinase/protein kinase B and AMP-activated protein kinase pathways.
Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Arctium; Carnitine O-Palmitoyltransferase; Fatty Liver; Furans; Hep G2 Cells; Hepatocytes; Humans; Inflammation; Intercellular Adhesion Molecule-1; Interleukins; Lignans; Liver; Non-alcoholic Fatty Liver Disease; Oleic Acid; Oxidative Stress; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Phytotherapy; Plant Extracts; PPAR alpha; Proto-Oncogene Proteins c-akt; Signal Transduction; Sterol Regulatory Element Binding Protein 1 | 2018 |
Effects of Rhizoma Alismatis extract on biochemical indices and adipose gene expression in oleic acid-induced hepatocyte injury in Jian carp (Cyprinus carpio var. Jian).
Topics: Alisma; Animals; Carps; Cell Survival; Cells, Cultured; Cytochrome P-450 Enzyme System; Fatty Liver; Fish Diseases; gamma-Glutamyltransferase; Gene Expression; Hepatocytes; L-Lactate Dehydrogenase; Lipid Metabolism; NF-kappa B; Oleic Acid; Plant Extracts; Rhizome; Transaminases; Tumor Necrosis Factor-alpha | 2018 |
MiRNA-17 encoded by the miR-17-92 cluster increases the potential for steatosis in hepatoma cells by targeting CYP7A1.
Topics: Animals; Cholesterol 7-alpha-Hydroxylase; Disease Models, Animal; Fatty Liver; Hep G2 Cells; Humans; Liver; Mice; Mice, Inbred C57BL; Mice, Transgenic; MicroRNAs; Oleic Acid | 2018 |
Trivalent Chromium Supplementation Ameliorates Oleic Acid-Induced Hepatic Steatosis in Mice.
Topics: Animals; Chromium; Dietary Supplements; Disease Models, Animal; Fatty Liver; Female; Hepatocytes; Lipid Metabolism; Mice; Mice, Inbred BALB C; Oleic Acid | 2019 |
Tetrahydrocurcumin ameliorates free fatty acid-induced hepatic steatosis and improves insulin resistance in HepG2 cells.
Topics: Curcumin; Fatty Acid-Binding Proteins; Fatty Acids, Nonesterified; Fatty Liver; Glucose; Hep G2 Cells; Humans; Insulin Resistance; Lipogenesis; Oleic Acid; PPAR alpha; Sterol Regulatory Element Binding Protein 1 | 2018 |
Procyanidin B2 ameliorates free fatty acids-induced hepatic steatosis through regulating TFEB-mediated lysosomal pathway and redox state.
Topics: Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Biflavonoids; Catechin; Diet, High-Fat; Fatty Acids, Nonesterified; Fatty Liver; Hep G2 Cells; Hepatocytes; Humans; Lipogenesis; Liver; Lysosomes; Metabolic Networks and Pathways; Mice; Molecular Docking Simulation; Non-alcoholic Fatty Liver Disease; Oleic Acid; Oxidation-Reduction; Oxidative Stress; Proanthocyanidins | 2018 |
Celecoxib alleviates AKT/c-Met-triggered rapid hepatocarcinogenesis by suppressing a novel COX-2/AKT/FASN cascade.
Topics: Animals; Apoptosis; Carcinogenesis; Carcinoma, Hepatocellular; Celecoxib; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Fatty Acid Synthase, Type I; Fatty Liver; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Mice; Oleic Acid; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-met; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2019 |
Histone H3K9 demethylase JMJD2B induces hepatic steatosis through upregulation of PPARγ2.
Topics: Animals; Diet, High-Fat; Fatty Liver; Gene Expression Regulation; Hep G2 Cells; Humans; Jumonji Domain-Containing Histone Demethylases; Liver; Mice; Mice, Obese; Non-alcoholic Fatty Liver Disease; Oleic Acid; Palmitic Acids; PPAR gamma; Triglycerides | 2018 |
[Establishment and optimization of hepatocyte steatosis model].
Topics: Cell Line; Fatty Liver; Hepatocytes; Humans; Lipid Metabolism; Oleic Acid | 2018 |
Dietary Polyphenols Protect Against Oleic Acid-Induced Steatosis in an in Vitro Model of NAFLD by Modulating Lipid Metabolism and Improving Mitochondrial Function.
Topics: Carnitine O-Palmitoyltransferase; Fatty Liver; Hep G2 Cells; Humans; Lipid Metabolism; Lipogenesis; Mitochondria, Liver; Non-alcoholic Fatty Liver Disease; Oleic Acid; Oxidation-Reduction; Polyphenols; Protective Agents | 2019 |
Effect of oleic acid on induction of steatosis and cytotoxicity in BRL 3A cells.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Cell Proliferation; Cells, Cultured; Fatty Liver; Hepatocytes; Lipids; Oleic Acid; Oxidative Stress; Rats | 2019 |
Daming capsule, a hypolipidaemic drug, lowers blood lipids by activating the AMPK signalling pathway.
Topics: AMP-Activated Protein Kinases; Animals; Cell Line, Tumor; China; Diet, High-Fat; Fatty Liver; Hep G2 Cells; Humans; Hyperlipidemias; Hypolipidemic Agents; Lipid Metabolism; Lipids; Lipoprotein Lipase; Liver; Male; Oleic Acid; PPAR alpha; Rats; Rats, Sprague-Dawley; Receptors, LDL; Signal Transduction; Triglycerides | 2019 |
Metabolomic signatures in lipid-loaded HepaRGs reveal pathways involved in steatotic progression.
Topics: Bile Acids and Salts; Diglycerides; Disease Progression; Fatty Liver; HEK293 Cells; Hep G2 Cells; Humans; Insulin; Insulin Resistance; Liver; Metabolome; Mitochondria; Monoglycerides; Non-alcoholic Fatty Liver Disease; Oleic Acid; Oxidative Stress; Palmitic Acid; Phosphorylation; Reactive Oxygen Species | 2013 |
The effects of aldosterone on diet-induced fatty liver formation in male C57BL/6 mice: comparison of adrenalectomy and mineralocorticoid receptor blocker.
Topics: Adrenalectomy; Aldosterone; Animals; Blood Glucose; Blood Pressure; Cells, Cultured; Cholesterol; Diet, High-Fat; Disease Models, Animal; Eplerenone; Fatty Liver; Hepatocytes; Insulin; Insulin Resistance; Lipoproteins, VLDL; Liver; Male; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Mineralocorticoid Receptor Antagonists; Oleic Acid; Spironolactone; Triglycerides; Weight Gain | 2013 |
Effects of trans-fatty acids on liver lipid metabolism in mice fed on diets showing different fatty acid composition.
Topics: Animals; Corn Oil; Dietary Fats; Fatty Liver; Gene Expression Regulation; Hydrogenation; Linoleic Acid; Lipid Metabolism; Lipogenesis; Liver; Male; Mice; Mice, Inbred Strains; Oleic Acid; Olive Oil; Oxidation-Reduction; Plant Oils; Random Allocation; Sterol Regulatory Element Binding Protein 1; Trans Fatty Acids; Triglycerides | 2013 |
Amelioration by chicory seed extract of diabetes- and oleic acid-induced non-alcoholic fatty liver disease (NAFLD)/non-alcoholic steatohepatitis (NASH) via modulation of PPARα and SREBP-1.
Topics: Animals; Chromatography, High Pressure Liquid; Cichorium intybus; Diabetes Complications; Fatty Liver; Hep G2 Cells; Humans; Male; Non-alcoholic Fatty Liver Disease; Oleic Acid; Plant Extracts; PPAR alpha; Rats; Rats, Wistar; Seeds; Sterol Regulatory Element Binding Protein 1 | 2013 |
The role of hepassocin in the development of non-alcoholic fatty liver disease.
Topics: Aged; Animals; Case-Control Studies; Cells, Cultured; Diet, High-Fat; Disease Models, Animal; Fatty Liver; Female; Fibrinogen; Gene Deletion; Hep G2 Cells; Hepatocytes; Humans; Lipid Metabolism; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Middle Aged; Neoplasm Proteins; Non-alcoholic Fatty Liver Disease; Oleic Acid | 2013 |
Depending on the stage of hepatosteatosis, p53 causes apoptosis primarily through either DRAM-induced autophagy or BAX.
Topics: Animals; Apoptosis; Autophagy; bcl-2-Associated X Protein; Dose-Response Relationship, Drug; Fatty Liver; Hep G2 Cells; Humans; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mitochondria; Oleic Acid; Real-Time Polymerase Chain Reaction; RNA Interference; Tumor Suppressor Protein p53 | 2013 |
[Effects of PPAR-alpha activation on oleic acid-induced steatosis and expression of heme oxygenase-1 in HepG2 cells].
Topics: Fatty Liver; Heme Oxygenase-1; Hep G2 Cells; Humans; Oleic Acid; PPAR alpha; Triglycerides | 2013 |
The inhibition of oleic acid induced hepatic lipogenesis and the promotion of lipolysis by caffeic acid via up-regulation of AMP-activated kinase.
Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Caffeic Acids; Cholesterol; Diet; Dietary Fats; Fatty Acid Synthesis Inhibitors; Fatty Liver; Gene Expression; Hep G2 Cells; Humans; Hypolipidemic Agents; Lipogenesis; Lipolysis; Liver; Non-alcoholic Fatty Liver Disease; Oleic Acid; Phosphorylation; Plant Extracts; Sterol Regulatory Element Binding Protein 1; Triglycerides; Up-Regulation | 2014 |
Aquaporin-9 downregulation prevents steatosis in oleic acid-induced non-alcoholic fatty liver disease cell models.
Topics: Aquaporins; Cell Line; Fatty Acids, Nonesterified; Fatty Liver; Glycerol; Humans; Non-alcoholic Fatty Liver Disease; Oleic Acid; Triglycerides | 2013 |
Accumulation of lipids and oxidatively damaged DNA in hepatocytes exposed to particles.
Topics: Animals; DNA Damage; DNA-Formamidopyrimidine Glycosylase; Fatty Acid Synthase, Type I; Fatty Liver; Fullerenes; Hep G2 Cells; Hepatocytes; Humans; Inflammation; Lipogenesis; Liver; Nitric Oxide Synthase Type II; Oleic Acid; Oxidative Stress; Palmitic Acid; Rats; Rats, Zucker; Reactive Oxygen Species; Soot; Stearoyl-CoA Desaturase; Sterol Regulatory Element Binding Protein 1; Vehicle Emissions | 2014 |
[Expression of aquaporin 3 and aquaporin 9 is regulated by oleic acid through the PI3K/Akt and p38 MAPK signaling pathways].
Topics: Aquaporin 3; Aquaporins; Fatty Liver; Gene Expression Regulation; Hep G2 Cells; Humans; Oleic Acid; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Signal Transduction | 2013 |
EZH2 down-regulation exacerbates lipid accumulation and inflammation in in vitro and in vivo NAFLD.
Topics: Adenosine; Animals; Disease Models, Animal; Down-Regulation; Enhancer of Zeste Homolog 2 Protein; Fatty Liver; Hep G2 Cells; Histones; Humans; MicroRNAs; Non-alcoholic Fatty Liver Disease; Oleic Acid; Palmitic Acid; Polycomb Repressive Complex 2; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2013 |
3,5-diiodo-L-thyronine modifies the lipid droplet composition in a model of hepatosteatosis.
Topics: Animals; Cell Line, Tumor; Diiodothyronines; Enzyme Inhibitors; Fatty Acids, Monounsaturated; Fatty Liver; Intracellular Signaling Peptides and Proteins; Lipase; Lipid Metabolism; Mitochondria, Liver; Models, Biological; Muscle Proteins; Oleic Acid; Oxidation-Reduction; Palmitic Acid; Perilipin-5; Rats | 2014 |
PPAR agonists reduce steatosis in oleic acid-overloaded HepaRG cells.
Topics: Cell Line; Constitutive Androstane Receptor; Drug Evaluation, Preclinical; Fatty Acids, Nonesterified; Fatty Liver; Gene Expression Regulation; Glycine; Humans; Lipid Metabolism; Lipogenesis; Lipotropic Agents; Liver; Liver X Receptors; Non-alcoholic Fatty Liver Disease; Oleic Acid; Orphan Nuclear Receptors; Oxazoles; Oxidation-Reduction; Peroxisome Proliferator-Activated Receptors; PPAR alpha; PPAR gamma; Receptors, Cytoplasmic and Nuclear; Triglycerides | 2014 |
Adiponutrin: a multimeric plasma protein.
Topics: Adult; Fatty Liver; Female; Hep G2 Cells; Human Umbilical Vein Endothelial Cells; Humans; Male; Membrane Proteins; Middle Aged; Non-alcoholic Fatty Liver Disease; Oleic Acid; Protein Multimerization | 2014 |
Hugan Qingzhi medication ameliorates hepatic steatosis by activating AMPK and PPARα pathways in L02 cells and HepG2 cells.
Topics: Adiponectin; AMP-Activated Protein Kinases; Animals; Antioxidants; Cell Line; Drugs, Chinese Herbal; Fatty Liver; Female; Hep G2 Cells; Humans; Oleic Acid; Oxidative Stress; Palmitic Acid; PPAR alpha; Rats, Sprague-Dawley | 2014 |
Elaidic acid (EA) generates dysfunctional high-density lipoproteins and consumption of EA exacerbates hyperlipidemia and fatty liver change in zebrafish.
Topics: Animals; Antioxidants; Apolipoprotein A-I; Atherosclerosis; Cells, Cultured; Cholesterol Ester Transfer Proteins; Embryo, Nonmammalian; Fatty Liver; Humans; Hyperlipidemias; Lipoproteins, HDL; Lipoproteins, LDL; Macrophages; Oleic Acid; Oleic Acids; Reactive Oxygen Species; Stearic Acids; Toxicity Tests, Acute; Trans Fatty Acids; Triglycerides; Zebrafish | 2014 |
Oleic acid-induced hepatic steatosis is coupled with downregulation of aquaporin 3 and upregulation of aquaporin 9 via activation of p38 signaling.
Topics: Aquaporin 3; Aquaporins; Down-Regulation; Fatty Liver; Gene Expression Regulation; Hep G2 Cells; Humans; MAP Kinase Signaling System; Non-alcoholic Fatty Liver Disease; Oleic Acid; RNA, Messenger; Triglycerides; Up-Regulation | 2015 |
Metformin alleviates hepatosteatosis by restoring SIRT1-mediated autophagy induction via an AMP-activated protein kinase-independent pathway.
Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Blood Glucose; Body Weight; Caloric Restriction; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus, Type 2; Down-Regulation; Fatty Liver; Hep G2 Cells; Hepatocytes; Humans; Lipid Metabolism; Liver; Metformin; Mice, Inbred C57BL; Mice, Obese; Models, Biological; Oleic Acid; Phagosomes; Signal Transduction; Sirtuin 1; Up-Regulation | 2015 |
Fatty Acids Induce a Pro-Inflammatory Gene Expression Profile in Huh-7 Cells That Attenuates the Anti-HCV Action of Interferon.
Topics: Cell Line; Cluster Analysis; Drug Synergism; Fatty Acids; Fatty Liver; Gene Expression Profiling; Gene Expression Regulation; Hepacivirus; Hepatitis C, Chronic; Humans; Interferons; NF-kappa B; Oleic Acid; Palmitic Acid; Toll-Like Receptor 2; Transcriptome; Virus Replication | 2015 |
Puerarin ameliorates hepatic steatosis by activating the PPARα and AMPK signaling pathways in hepatocytes.
Topics: AMP-Activated Protein Kinases; Fatty Liver; Gene Expression Regulation; Hep G2 Cells; Hepatocytes; Humans; Isoflavones; Lipid Metabolism; Oleic Acid; PPAR alpha; RNA, Messenger; Signal Transduction | 2015 |
Sechium edule Shoot Extracts and Active Components Improve Obesity and a Fatty Liver That Involved Reducing Hepatic Lipogenesis and Adipogenesis in High-Fat-Diet-Fed Rats.
Topics: Adipogenesis; AMP-Activated Protein Kinases; Animals; Body Weight; Cucurbitaceae; Diet, High-Fat; Fatty Liver; Humans; Hydroxymethylglutaryl CoA Reductases; Lipogenesis; Liver; Male; Obesity; Oleic Acid; Plant Extracts; Plant Shoots; Rats; Rats, Wistar; Sterol Regulatory Element Binding Protein 1 | 2015 |
Anthocyanin-rich extracts from blackberry, wild blueberry, strawberry, and chokeberry: antioxidant activity and inhibitory effect on oleic acid-induced hepatic steatosis in vitro.
Topics: Animals; Anthocyanins; Antioxidants; Blueberry Plants; Fatty Liver; Fragaria; Fruit; Hep G2 Cells; Humans; Lipid Metabolism; Oleic Acid; Plant Extracts; Prunus; Rubus | 2016 |
Establishment of a hepatocyte steatosis model using Chang liver cells.
Topics: Cell Line; Fatty Liver; Hepatocytes; Humans; Liver; Non-alcoholic Fatty Liver Disease; Oleic Acid; Triglycerides | 2015 |
[Sodium nitrite reduces lipid accumulation in steatotic cells by enhancing autophagy].
Topics: Adenine; Autophagy; Blotting, Western; Cells, Cultured; Chloroquine; Cytoplasm; Fatty Liver; Hepatocytes; Humans; Lipid Metabolism; Microscopy, Fluorescence; Microtubule-Associated Proteins; Oleic Acid; Sodium Nitrite; Triglycerides | 2015 |
Supplementing dietary sugar promotes endoplasmic reticulum stress-independent insulin resistance and fatty liver in goose.
Topics: Animals; Cells, Cultured; Dietary Carbohydrates; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Fatty Liver; Geese; Gene Expression; Glucose; Glucose Tolerance Test; Heat-Shock Proteins; Hepatocytes; Insulin Resistance; Oleic Acid; Organ Size; Palmitic Acid | 2016 |
Dihydromyricetin ameliorates oleic acid-induced lipid accumulation in L02 and HepG2 cells by inhibiting lipogenesis and oxidative stress.
Topics: Fatty Liver; Flavonols; Hep G2 Cells; Humans; Lipid Metabolism; Lipogenesis; Oleic Acid; Oxidative Stress | 2016 |
Deletion of Gab2 in mice protects against hepatic steatosis and steatohepatitis: a novel therapeutic target for fatty liver disease.
Topics: Adaptor Proteins, Signal Transducing; Animals; Disease Models, Animal; Ethanol; Fatty Liver; Gene Deletion; GRB2 Adaptor Protein; Hep G2 Cells; Hepatocytes; Humans; Lipids; Liver; Mice; Mice, Inbred C57BL; Models, Biological; Molecular Targeted Therapy; Oleic Acid; Phosphoproteins; Protective Agents; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Signal Transduction | 2016 |
Silybin counteracts lipid excess and oxidative stress in cultured steatotic hepatic cells.
Topics: Animals; Antioxidants; Blotting, Western; Carnitine O-Palmitoyltransferase; Catalase; Cell Line, Tumor; Cells, Cultured; Fatty Liver; Fluorometry; Hepatocytes; Lipid Droplets; Lipid Metabolism; Lipid Peroxidation; Microscopy, Fluorescence; NF-kappa B; Oleic Acid; Oxidative Stress; Palmitates; Peroxisome Proliferator-Activated Receptors; Rats; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Silybin; Silymarin; Spectrophotometry; Sterol Regulatory Element Binding Protein 1; Triglycerides; Vitamin E | 2016 |
Swertiamarin ameliorates oleic acid induced lipid accumulation and oxidative stress by attenuating gluconeogenesis and lipogenesis in hepatic steatosis.
Topics: AMP-Activated Protein Kinases; Apoptosis; Caspase 3; Cell Membrane; Enzyme Activation; Fatty Liver; Gene Expression Regulation; Gluconeogenesis; Hep G2 Cells; Hepatocytes; Humans; Inflammation; Insulin; Insulin Resistance; Iridoid Glucosides; Lipogenesis; Oleic Acid; Oxidative Stress; Poly(ADP-ribose) Polymerases; Protective Agents; Pyrones; Reproducibility of Results; Signal Transduction; Triglycerides | 2016 |
Trivalent chromium alleviates oleic acid induced steatosis in SMMC-7721 cells by decreasing fatty acid uptake and triglyceride synthesis.
Topics: Cell Survival; Chromium; Diacylglycerol O-Acyltransferase; Dose-Response Relationship, Drug; Down-Regulation; Fatty Acids; Fatty Liver; Humans; Oleic Acid; Structure-Activity Relationship; Triglycerides; Tumor Cells, Cultured | 2016 |
Prolyl Oligopeptidase Inhibition Attenuates Steatosis in the L02 Human Liver Cell Line.
Topics: Apoptosis; Cell Line; Cell Proliferation; Enzyme Inhibitors; Fatty Liver; Gene Expression Regulation, Enzymologic; Humans; Indoles; Lipid Metabolism; Liver; Models, Biological; Oleic Acid; Palmitic Acid; Prolyl Oligopeptidases; Serine Endopeptidases; Thiazolidines; Triglycerides; Up-Regulation | 2016 |
Human leucine zipper protein promotes hepatic steatosis
Topics: Apolipoproteins A; Cyclic AMP Response Element-Binding Protein; Fatty Liver; Gene Expression Regulation; Golgi Apparatus; Hep G2 Cells; Hepatocytes; Humans; Lipid Metabolism; Mutation; Oleic Acid; Phosphorylation; Plasmids; Proto-Oncogene Proteins c-akt; RNA, Messenger; Stress, Physiological | 2017 |
Elevated expression of osteopontin may be related to adipose tissue macrophage accumulation and liver steatosis in morbid obesity.
Topics: Adipose Tissue; Adult; Animals; Cell Line, Tumor; Fatty Liver; Female; Gene Expression; Humans; Hyaluronan Receptors; Immunoblotting; Liver; Macrophages; Male; Mice; Mice, Inbred C57BL; Middle Aged; Obesity, Morbid; Oleic Acid; Osteopontin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha; Weight Loss | 2009 |
Differential effect of oleic and palmitic acid on lipid accumulation and apoptosis in cultured hepatocytes.
Topics: Apoptosis; Cell Line, Tumor; Dose-Response Relationship, Drug; Fatty Liver; Gene Expression Regulation; Hepatocytes; Humans; Insulin; Oleic Acid; Palmitic Acid; PPAR alpha; PPAR gamma; Receptor, Insulin; RNA, Messenger; Signal Transduction; Sterol Regulatory Element Binding Protein 1; Triglycerides | 2009 |
Trans fat feeding results in higher serum alanine aminotransferase and increased insulin resistance compared with a standard murine high-fat diet.
Topics: Alanine Transaminase; Animals; Cholesterol; Dietary Fats; Fatty Liver; Inflammation Mediators; Insulin; Insulin Resistance; Interleukin-1beta; Leptin; Liver; Male; Mice; Oleic Acid; Oleic Acids; Severity of Illness Index; Time Factors; Trans Fatty Acids; Triglycerides; Up-Regulation; Weight Gain | 2009 |
C/EBP beta and C/EBP delta expression is elevated in the early phase of ethanol-induced hepatosteatosis in mice.
Topics: Adipogenesis; Animals; CCAAT-Enhancer-Binding Protein-delta; CCAAT-Enhancer-Binding Proteins; Cell Line, Tumor; Ethanol; Fatty Liver; Gene Expression Regulation; Humans; Liver; Male; Mice; Mice, Inbred C57BL; Oleic Acid | 2009 |
Lipotoxicity: why do saturated fatty acids cause and monounsaturates protect against it?
Topics: Apoptosis; Cytoprotection; Fatty Liver; Hepatocytes; Humans; Oleic Acid; Palmitic Acid; PPAR alpha; PPAR gamma; Receptors, G-Protein-Coupled; Signal Transduction; Triglycerides | 2009 |
Palmitate induces insulin resistance without significant intracellular triglyceride accumulation in HepG2 cells.
Topics: Azo Compounds; Blotting, Western; Cell Line; Chromatography, Thin Layer; Endoplasmic Reticulum; Fatty Acids, Nonesterified; Fatty Liver; Fluorometry; Histocytochemistry; Humans; Insulin Resistance; Lipids; Liver; Molecular Chaperones; Oleic Acid; Oxazines; Palmitates; Triglycerides | 2010 |
[An in vitro hepatic steatosis cell model for study of non-alcoholic fatty liver disease].
Topics: Culture Media; Fatty Acids, Nonesterified; Fatty Liver; Hep G2 Cells; Humans; Models, Biological; Non-alcoholic Fatty Liver Disease; Oleic Acid; Palmitates | 2009 |
Dietary trans fatty acid isomers differ in their effects on mammary lipid metabolism as well as lipogenic gene expression in lactating mice.
Topics: 1-Acylglycerol-3-Phosphate O-Acyltransferase; Animals; Dietary Fats; Fatty Liver; Female; Gene Expression Regulation; Isomerism; Lactation; Linoleic Acids, Conjugated; Lipid Metabolism; Lipogenesis; Liver; Mammary Glands, Animal; Mice; Mice, Inbred Strains; Milk; Nuclear Proteins; Oleic Acid; Organ Size; Plant Oils; Random Allocation; RNA, Messenger; Stereoisomerism; Trans Fatty Acids; Transcription Factors | 2010 |
CHOP and AP-1 cooperatively mediate PUMA expression during lipoapoptosis.
Topics: Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Binding Sites; Cell Line, Tumor; Endoplasmic Reticulum; Fatty Liver; Hepatocytes; Humans; Oleic Acid; Palmitic Acid; Phosphorylation; Promoter Regions, Genetic; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-jun; RNA Interference; RNA, Messenger; Transcription Factor AP-1; Transcription Factor CHOP; Transcriptional Activation; Transfection; Up-Regulation | 2010 |
Insulin- and leptin-regulated fatty acid uptake plays a key causal role in hepatic steatosis in mice with intact leptin signaling but not in ob/ob or db/db mice.
Topics: Aging; Animals; Body Weight; Energy Intake; Ethanol; Fatty Acid Transport Proteins; Fatty Acids; Fatty Liver; Gene Expression Regulation; Insulin; Leptin; Lipids; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Oleic Acid; Organ Size; Random Allocation; Receptors, Leptin; Signal Transduction | 2010 |
Cannabinoid receptor 1 and 2 agonists increase lipid accumulation in hepatocytes.
Topics: Apolipoproteins B; Arachidonic Acids; Biological Transport; Blotting, Western; Cannabinoids; Carnitine O-Palmitoyltransferase; Dose-Response Relationship, Drug; Fatty Acid Synthase, Type I; Fatty Liver; Gene Expression Regulation; Hep G2 Cells; Hepatocytes; Humans; Lipid Metabolism; Non-alcoholic Fatty Liver Disease; Oleic Acid; Phosphatidylcholine-Sterol O-Acyltransferase; Receptor Cross-Talk; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Reverse Transcriptase Polymerase Chain Reaction; Sterol Regulatory Element Binding Protein 1; Triglycerides; Up-Regulation | 2010 |
Screening and identification of differentially expressed genes in goose hepatocytes exposed to free fatty acid.
Topics: Animals; Caspase 3; Cells, Cultured; Fatty Acids, Nonesterified; Fatty Liver; Geese; Gene Expression; Hepatocytes; Oleic Acid; Palmitic Acids; Polymerase Chain Reaction | 2010 |
A protective role for CD154 in hepatic steatosis in mice.
Topics: Animals; Apolipoprotein B-100; CD40 Ligand; Cells, Cultured; Fatty Liver; Hep G2 Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Knockout; Oleic Acid; Unfolded Protein Response | 2010 |
Direct effects of iodothyronines on excess fat storage in rat hepatocytes.
Topics: Acyl-CoA Oxidase; Animals; Catalase; Cells, Cultured; Diiodothyronines; Fatty Liver; Gene Expression; Hepatocytes; Lipid Metabolism; Non-alcoholic Fatty Liver Disease; Oleic Acid; Palmitates; PPAR alpha; PPAR delta; PPAR gamma; Rats; RNA, Messenger; Superoxide Dismutase; Triiodothyronine | 2011 |
Tracking cellular metabolomics in lipoapoptosis- and steatosis-developing liver cells.
Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Citric Acid Cycle; Fatty Liver; Gas Chromatography-Mass Spectrometry; Glycolysis; Liver Neoplasms; Metabolome; Metabolomics; Oleic Acid; Palmitates; Pentose Phosphate Pathway; Rats; Reactive Oxygen Species; Signal Transduction | 2011 |
Induction of vesicular steatosis by amiodarone and tetracycline is associated with up-regulation of lipogenic genes in HepaRG cells.
Topics: Amiodarone; Carcinoma, Hepatocellular; Carrier Proteins; Cell Line, Tumor; Down-Regulation; Fatty Acid Synthase, Type I; Fatty Liver; Humans; Lipid Metabolism; Lipogenesis; Liver Neoplasms; Membrane Proteins; Oleic Acid; Perilipin-2; Perilipin-4; Phosphoproteins; Stearoyl-CoA Desaturase; Tetracycline; Triglycerides; Up-Regulation | 2011 |
Cellular glutathione in fatty liver in vitro models.
Topics: Dose-Response Relationship, Drug; Fatty Liver; Female; Glutathione; Hep G2 Cells; Hepatocytes; Humans; Lipid Peroxidation; Lipid Peroxides; Male; Middle Aged; Models, Biological; Oleic Acid; Oxidative Stress; Palmitic Acid | 2011 |
ATF4 deficiency protects mice from high-carbohydrate-diet-induced liver steatosis.
Topics: Activating Transcription Factor 4; Adipose Tissue; Administration, Oral; Animals; Diet; Dietary Carbohydrates; Dietary Supplements; Energy Metabolism; Fatty Liver; Glucose Tolerance Test; Insulin; Liver; Mice; Oleic Acid; Stearoyl-CoA Desaturase; Triglycerides | 2011 |
Comparative study on antioxidant capacity of flavonoids and their inhibitory effects on oleic acid-induced hepatic steatosis in vitro.
Topics: Antioxidants; Cell Line; Fatty Liver; Flavonoids; Humans; In Vitro Techniques; Oleic Acid; Reactive Oxygen Species; Triglycerides | 2011 |
Differential roles of unsaturated and saturated fatty acids on autophagy and apoptosis in hepatocytes.
Topics: Adenoviridae; Animals; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Caspase 3; Diet, High-Fat; Fatty Acids, Unsaturated; Fatty Liver; Hep G2 Cells; Hepatocytes; Humans; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Oleic Acid; Palmitic Acid; Reactive Oxygen Species; TOR Serine-Threonine Kinases; Triglycerides | 2011 |
Rilmenidine improves hepatic steatosis through p38-dependent pathway to higher the expression of farnesoid X receptor.
Topics: Animals; Calcium; Cell Line, Tumor; Diet, High-Fat; Egtazic Acid; Fatty Liver; Humans; Imidazoline Receptors; Lipid Metabolism; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Oleic Acid; Oxazoles; Receptors, Cytoplasmic and Nuclear; Rilmenidine | 2012 |
Inhibitory effect of blueberry polyphenolic compounds on oleic acid-induced hepatic steatosis in vitro.
Topics: Blueberry Plants; Fatty Liver; Hep G2 Cells; Humans; Models, Biological; Non-alcoholic Fatty Liver Disease; Oleic Acid; Plant Extracts; Polyphenols; Protective Agents; Triglycerides | 2011 |
Relationship of glucose and oleate metabolism to cardiac function in lipin-1 deficient (fld) mice.
Topics: Animals; Fatty Liver; Glucose; Heart; In Vitro Techniques; Male; Mice; Myocardium; Nuclear Proteins; Oleic Acid; Phosphatidate Phosphatase; Triglycerides | 2012 |
Effect of intracellular lipid accumulation in a new model of non-alcoholic fatty liver disease.
Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cytokines; Dose-Response Relationship, Drug; Fatty Acids, Nonesterified; Fatty Liver; Hepatocytes; Humans; In Vitro Techniques; Lipid Metabolism; Liver Neoplasms; Models, Biological; Non-alcoholic Fatty Liver Disease; Oleic Acid; Oxidative Stress; Palmitic Acid; Reactive Oxygen Species | 2012 |
Liv.52 up-regulates cellular antioxidants and increase glucose uptake to circumvent oleic acid induced hepatic steatosis in HepG2 cells.
Topics: Antioxidants; Biomarkers; Cell Proliferation; Cytokines; DNA Fragmentation; Drug Combinations; Drug Evaluation, Preclinical; Fatty Liver; Glucose; Glutathione; Hep G2 Cells; Humans; Lipid Peroxidation; Oleic Acid; Plant Extracts; Triglycerides | 2012 |
Solute carrier family 2 member 1 is involved in the development of nonalcoholic fatty liver disease.
Topics: Adolescent; Adult; Aged; Diabetes Mellitus, Type 2; Fatty Liver; Female; Gene Frequency; Gene Silencing; Genetic Predisposition to Disease; Glucose Transporter Type 1; Humans; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Oleic Acid; Oxidative Stress; Polymorphism, Single Nucleotide; Transcriptome | 2013 |
Quercetin ameliorate insulin resistance and up-regulates cellular antioxidants during oleic acid induced hepatic steatosis in HepG2 cells.
Topics: Alanine Transaminase; Albumins; Antioxidants; Cytokines; DNA Fragmentation; Fatty Liver; Glucose; Glutathione; Hep G2 Cells; Humans; Insulin Resistance; Lipid Peroxidation; Oleic Acid; Quercetin; RNA, Messenger; Tumor Necrosis Factor-alpha; Up-Regulation; Urea | 2013 |
LIVER LIPID ACCUMULATION IN ISOLEUCINE-DEFICIENT RATS.
Topics: Acetates; Blood Chemical Analysis; Carbon Isotopes; Cholesterol; Electrophoresis; Fatty Acids; Fatty Acids, Essential; Fatty Liver; Histocytochemistry; Isoleucine; Linoleic Acid; Lipid Metabolism; Lipoproteins; Liver; Liver Glycogen; Nitrogen; Oleic Acid; Palmitic Acid; Phospholipids; Protein Deficiency; Proteins; Rats; Research; Stearic Acids | 1964 |
EFFECTS OF PALMITIC, OLEIC, AND LINOLEIC ACIDS ON HEPATIC AND VASCULAR LIPID DEPOSITS.
Topics: Cholesterol; Chromatography; Cocos; Cottonseed Oil; Dietary Fats; Fatty Acids; Fatty Liver; Glycerides; Linoleic Acid; Linoleic Acids; Lipids; Oils; Oleic Acid; Oleic Acids; Palmitic Acid; Pathology; Phospholipids; Rats; Research; Toxicology | 1963 |
FATTY ACID COMPOSITION OF PORTAL FATTY LIVER IN LYSINE- AND THREONINE-DEFICIENT RATS.
Topics: Dietary Fats; Fatty Acids; Fatty Acids, Essential; Fatty Liver; Linoleic Acid; Lipids; Lysine; Metabolism; Oleic Acid; Palmitic Acid; Phospholipids; Protein Deficiency; Rats; Research; Stearic Acids; Threonine | 1964 |
LIVER LIPIDS IN A CASE OF HYPERVITAMINOSIS A.
Topics: Chemical and Drug Induced Liver Injury; Cholesterol; Chromatography; Fatty Acids; Fatty Acids, Essential; Fatty Liver; Geriatrics; Hepatitis; Hypervitaminosis A; Linoleic Acid; Lipid Metabolism; Lipids; Liver; Oleic Acid; Palmitic Acid; Phospholipids; Toxicology; Vitamin K | 1965 |
FATTY ACID COMPOSITION OF RAT LIVER LIPIDS DURING CHOLINE DEFICIENCY.
Topics: Choline; Choline Deficiency; Dietary Fats; Dietary Proteins; Fatty Acids; Fatty Acids, Essential; Fatty Liver; Fish Oils; Histocytochemistry; Linoleic Acid; Lipid Metabolism; Lipids; Oleic Acid; Palmitic Acid; Proteins; Rats; Research; Stearic Acids | 1965 |
Free fatty acids promote hepatic lipotoxicity by stimulating TNF-alpha expression via a lysosomal pathway.
Topics: Animals; Antigens, CD; bcl-2-Associated X Protein; Cathepsin B; Cells, Cultured; Cytosol; Diet; Drug Combinations; Fatty Acids, Nonesterified; Fatty Liver; Humans; Liver; Lysosomes; Mice; Mice, Knockout; NF-kappa B; Oleic Acid; Palmitates; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Severity of Illness Index; Tissue Distribution; Tumor Necrosis Factor-alpha | 2004 |
A human hepatocellular in vitro model to investigate steatosis.
Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Fatty Acids, Nonesterified; Fatty Liver; Hepatocytes; Humans; In Vitro Techniques; Neutral Red; Oleic Acid; Palmitic Acid | 2007 |
Free fatty acids sensitise hepatocytes to TRAIL mediated cytotoxicity.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Cells, Cultured; Fatty Acids, Nonesterified; Fatty Liver; Hepatocytes; Humans; Immunohistochemistry; JNK Mitogen-Activated Protein Kinases; Oleic Acid; Rats; Receptors, TNF-Related Apoptosis-Inducing Ligand; Recombinant Proteins; Stearic Acids; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha | 2007 |
Microarray analyses and molecular profiling of steatosis induction in immortalized human hepatocytes.
Topics: Apoptosis; Cell Line, Transformed; Cell Proliferation; Cell Survival; Cells, Cultured; Fatty Liver; Gene Expression Profiling; Hepatocytes; Humans; Insulin; Insulin Resistance; Lipid Metabolism; Oleic Acid; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction | 2007 |
Lysophosphatidylcholine as a death effector in the lipoapoptosis of hepatocytes.
Topics: Apoptosis; Cell Line; Cell Line, Tumor; Cytochromes c; Enzyme Inhibitors; Fatty Liver; Hepatocytes; Humans; Lipid Metabolism; Liver; Lysophosphatidylcholines; Oleic Acid; Palmitic Acid; Phospholipases A2; Receptors, G-Protein-Coupled; RNA, Small Interfering | 2008 |
Hepatic stearoyl-CoA desaturase-1 deficiency protects mice from carbohydrate-induced adiposity and hepatic steatosis.
Topics: Adiposity; Animals; Base Sequence; Carbohydrate Metabolism; Dietary Carbohydrates; Dietary Fats; DNA Primers; Fatty Liver; Gluconeogenesis; Lipogenesis; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; Oleic Acid; Stearoyl-CoA Desaturase; Sucrose; Tissue Distribution | 2007 |
Inhibition of apolipoprotein B100 secretion by lipid-induced hepatic endoplasmic reticulum stress in rodents.
Topics: Animals; Apolipoprotein B-100; Cell Line; Endoplasmic Reticulum; Fatty Acids, Nonesterified; Fatty Liver; Insulin Resistance; Lipoproteins, VLDL; Liver; Mice; Oleic Acid; Proteasome Endopeptidase Complex; Stress, Physiological; Time Factors; Triglycerides | 2008 |
Fat infiltration in liver of rats induced by different dietary plant oils: high oleic-, medium oleic- and high petroselinic acid-oils.
Topics: Animals; Dietary Fats, Unsaturated; Fatty Liver; Isomerism; Liver; Male; Oleic Acid; Oleic Acids; Plant Oils; Rats; Rats, Wistar | 1996 |
The effect of carnitine on ketogenesis in perfused livers from juvenile visceral steatosis mice with systemic carnitine deficiency.
Topics: Animals; Butyrates; Butyric Acid; Caprylates; Carnitine; Disease Models, Animal; Fatty Liver; In Vitro Techniques; Ketone Bodies; Liver; Mice; Mice, Mutant Strains; Oleic Acid; Perfusion | 1997 |
Hepatic fatty acid composition in periparturient dairy cows with fatty liver induced by intake of a high energy diet in the dry period.
Topics: 3-Hydroxybutyric Acid; Animals; Cattle; Cattle Diseases; Energy Intake; Fatty Acids; Fatty Acids, Nonesterified; Fatty Liver; Female; Glycogen; Linoleic Acid; Lipolysis; Liver; Oleic Acid; Palmitic Acid; Pregnancy; Stearic Acids; Triglycerides | 1999 |
Interrelation of fatty acid composition in adipose tissue, serum, and liver of dairy cows during the development of fatty liver postpartum.
Topics: Adipose Tissue; Animals; Cattle; Cattle Diseases; Diet; Energy Intake; Fatty Acids; Fatty Acids, Nonesterified; Fatty Liver; Female; Linoleic Acid; Lipolysis; Liver; Oleic Acid; Palmitic Acid; Puerperal Disorders; Stearic Acids; Triglycerides; Weight Gain | 2000 |
Subcutaneous lipectomy causes a metabolic syndrome in hamsters.
Topics: Adipose Tissue; Animals; Body Composition; Carbon Radioisotopes; Cricetinae; Dietary Fats; Fatty Liver; Female; Glucose; Glucose Tolerance Test; Insulin; Insulin Resistance; Leptin; Lipectomy; Liver; Liver Diseases; Mesocricetus; Obesity; Oleic Acid; Organ Size; Skin; Triglycerides | 2000 |