oleic acid and Diabetes Mellitus, Type 2

oleic acid has been researched along with Diabetes Mellitus, Type 2 in 74 studies

Research

Studies (74)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.35)18.7374
1990's12 (16.22)18.2507
2000's24 (32.43)29.6817
2010's29 (39.19)24.3611
2020's8 (10.81)2.80

Authors

AuthorsStudies
Hüttl, M; Malinska, H; Markova, I; Miklankova, D; Stankova, B1
Angeles, ZE; Castell, AL; Filali-Mouhim, A; Ghislain, J; Poitout, V; Sladek, R; Vivoli, A1
ALjohani, A; Assadi-Porter, F; Burhans, MS; Kalyesubula, M; Liu, X; Ntambi, JM; Selen, ES1
Bagnati, M; Berry, MD; Billacura, MP; Caton, PW; Cripps, MJ; Fair, K; Hanna, K; Hitman, GA; Jones, TA; Lowe, R; Nelson, C; Ogunkolade, BW; Sayers, SR; Turner, MD1
Akash, MSH; Haider, K; Jabeen, K; Rehman, K1
Banerjee, A; Sharma, D; Singh, J; Trivedi, R1
Kang, BC; Lee, E; Lee, HS; Suh, JY1
Musselman, LP; O'Hara, E; Quaglia, CJ; Tuthill Ii, BF1
Gao, LP; Jing, YH; Lv, DD; Qi, CC; Song, YF; Wang, DG; Yin, J; Zhang, L1
Aiello, F; Badolato, M; Brizzi, A; Caroleo, MC; Carullo, G; Cione, E; Di Gioia, ML; Manetti, F; Perri, M1
Barroso, E; Palomer, X; Pizarro-Delgado, J; Vázquez-Carrera, M1
Hansen, HS; Hansen, KB; Holst, JJ; Knop, FK; Mandøe, MJ; Rehfeld, JF; Rosenkilde, MM; Windeløv, JA1
Dobrzyn, A; Dobrzyn, P; Dziewulska, A; Janikiewicz, J; Jazurek-Ciesiolka, M; Kozinski, K1
Eckel, J; Greulich, S; Knoefel, WT; Lichtenberg, A; Maxhera, B; Ouwens, DM; Ruppe, F; Schlich, R; Sell, H; Willems, M1
Guo, C; He, L; Liu, HH; Liu, XD; Pan, GY; Ren, J; Sheng, JJ; Yang, Y; Yao, D; Zhou, WP1
Abia, R; Bermudez, B; Lopez, S; Muriana, FJ; Ortega-Gomez, A; Varela, LM; Villar, J1
Baek, SH; Cho, JS; Kim, JY; Kim, OY; Lee, JH1
Cameron-Smith, D; Cornall, LM; Hryciw, DH; McAinch, AJ; O'Brien, PE; Watts, R1
Mitjavila, MT; Moreno, JJ; Pintó, X; Roselló-Catafau, J; Storniolo, CE1
Cha, BS; Ham, DS; Kang, ES; Kim, JW; Lee, BW; Lee, HC; Lee, YH; Song, YM1
Aas, V; Bakke, SS; Damlien, L; Feng, YZ; Hjelmesæth, J; Kase, ET; Ludahl, MO; Moro, C; Nikolić, N; Rustan, AC; Sandbu, R; Solheim, BM; Stensrud, C; Thoresen, GH1
Badin, PM; Bakke, SS; Coue, M; Feng, YZ; Gaster, M; Kase, ET; Langin, D; Laurens, C; Moro, C; Rustan, AC; Thoresen, GH1
Buechler, C; Eisinger, K; Krautbauer, S; Meier, EM; Pohl, R; Rein-Fischboeck, L; Weiss, TS1
Baldi, S; Frascerra, S; Marraccini, P; Natali, A; Neglia, D; Tricò, D; Venturi, E1
Albrechtsen, A; Andersen, MK; Bjerregaard, P; Færgeman, NJ; Grarup, N; Hansen, T; Jørgensen, ME; Jørsboe, E; Moltke, I; Pedersen, O; Sandholt, CH1
Bao, Y; Chen, T; Hu, C; Jia, W; Liu, J; Ma, X; Ni, Y; Panee, J; Su, M; Wang, C; Xie, G; Yu, H; Zhao, A; Zhao, L1
Choi, HW; Koh, WP; Lu, Y; Ong, CN; Pan, A; Subramaniam, T; Wang, Y; Yuan, JM1
Bedrood, S; Chow, RH; Isas, JM; Langen, R; Okada, AK; Teranishi, K1
Berge, RK; Drevon, CA; Gaster, M; Just, M; Rustan, AC; Wensaas, AJ1
Gwiazda, KS; Johnson, JD; Lin, Y; Yang, TL1
Chakraborty, G; Garcia, C; Gonzalez, A; Tadros, JH; Toney, JH; Vassiliou, EK1
Fritz, T; Osler, ME; Rune, A; Zierath, JR1
Chen, J; Cheng, J; Huang, H; Li, J; Li, X; Liang, J; Liu, X; Long, Y; Ran, X; Tian, H; Wu, W1
Bala, M; Buechler, C; Kopp, A; Neumeier, M; Schäffler, A; Sporrer, D; Stögbauer, F; Wanninger, J; Weber, M; Weigert, J; Wurm, S1
Bergsten, P; Hovsepyan, M; Sargsyan, E1
Bakke, SS; Blaak, EE; Corpeleijn, E; Gaster, M; Hessvik, NP; Levin, K; Rustan, AC; Thoresen, GH1
Li, L; Liu, P; Liu, Y; Peng, G; Pu, J; Yu, J; Zhang, S; Zhao, J1
Hatayama, T; Mori, A; Saito, Y; Ueda, T; Yamagishi, N1
Jong, SA; Manning, PJ; Ryalls, AR; Sutherland, WH1
Brindamour, LJ; Habener, JF; Liu, Z; Stanojevic, V1
Aransay, AM; Aspichueta, P; Banasik, K; Buque, X; Caballeria, J; Castro, A; Clement, K; Echevarria-Uraga, JJ; Garcia-Monzon, C; Garcia-Rodriguez, JL; Gonzalez-Lahera, A; Gual, P; Hansen, T; Joergensen, T; Justesen, JM; Lauritzen, T; Le Marchand-Brustel, Y; Lozano, JJ; Martin-Duce, A; Martinez-Arranz, I; Martinez-Chantar, ML; Mato, JM; Mendibil, I; Pedersen, O; Regueiro, MM; Rodriguez-Ezpeleta, N; Schlangen, KA; Tordjman, J; Tran, A; Vazquez-Chantada, M; Veyrie, N; Witte, DR1
Bandinelli, S; Browning, BL; Chen, YD; Djousse, L; Ferrucci, L; Fornage, M; Foy, M; Fretts, AM; Gu, X; Guan, W; Jacobs, DR; Johnson, C; Kabagambe, EK; King, IB; Laurie, CC; Lemaitre, RN; Manichaikul, A; McKnight, B; Mozaffarian, D; Nettleton, JA; Psaty, BM; Rich, SS; Siscovick, D; Steffen, LM; Tanaka, T; Tang, W; Tsai, MY; Wu, JH1
Aspinwall, CA; Berggren, PO; Brandhorst, H; Bränström, R; Corkey, BE; Eckhard, M; Larsson, O; Ostensson, CG; Tibell, A; Välimäki, S1
Beck-Nielsen, H; Gaster, M; Rustan, AC1
Niu, G; Tan, H; Xiao, M; Zhang, Y1
Armoni, M; Bar-Yoseph, F; Harel, C; Karnieli, E; Milo, S1
Alho, H; Kunnas, T; Leskinen, MH; Nikkari, ST; Solakivi, T1
Fritsche, A; Häring, HU; Machicao, F; Staiger, H; Stefan, N1
Cardona, F; de la Cruz Almaráz, M; Esteva, I; Morcillo, S; Olveira, G; Rojo-Martínez, G; Ruiz de Adana, Mde L; Soriguer, F; Tinahones, F1
Caffall, Z; Ferguson, DC; Hoenig, M1
Allister, EM; Bikopoulos, G; Fantus, IG; Giacca, A; Lewis, GF; Naassan, A; Oprescu, AI; Park, E; Rozakis-Adcock, M; Tang, C; Uchino, H; Wheeler, MB1
Adams-Huet, B; Brinkley, L; Garg, A; Grundy, SM; Shah, M1
Gao, H; He, J; Liang, Y; Yi, L; Yuan, D; Zhou, H1
Dembele, K; Hernandez, TA; Nguyen, KH; Nyomba, BL1
Colette, C; Crastes de Paulet, A; Gouzes, C; Michel, F; Monnier, L; Rodier, M1
Galuska, D; Nolte, L; Smedegaard Kristensen, JS; Wahlström, E; Wallberg-Henriksson, H; Zierath, JR1
Kelley, DE; Simoneau, JA1
Collins, P; Dimitriadis, E; Griffin, ME; Johnson, A; Lenehan, K; Owens, D; Tomkin, GH1
Collins, P; Dimitriadis, E; Griffin, M; Johnson, A; Owens, D; Tomkin, GH1
Eto, M; Iwashima, Y; Makino, I; Okada, M; Saito, M1
Berk, PD; Bradbury, M; Isola, LM; Kiang, CL; Stump, D; Zhou, SL2
Baumstark, MW; Galle, J; Königer, M; Krämer-Guth, A; März, W; Nauck, M; Quaschning, T; Schollmeyer, P; Wanner, C1
Bollheimer, LC; Chester, MW; McGarry, JD; Rhodes, CJ; Skelly, RH1
Peterson, DB1
Collins, P; Johnson, A; McInerney, D; Owens, D; Ryan, M; Tomkin, GH1
Collins, P; Madigan, C; Owens, D; Ryan, M; Tomkin, GH1
Bloom, SR; Brynes, AE; Edwards, CM; Frost, GS; Ghatei, MA; Jadhav, A1
Haban, P; Klvanova, J; Zidekova, E1
Higashi, K; Ishikawa, T; Ito, T; Nakajima, K; Nakamura, H; Ohsuzu, F; Shige, H1
Abadie, JM; Malcom, GT; Porter, JR; Svec, F1
Ishimura, N; Mawatari, K; Minami, A; Nakaya, Y; Okada, K; Sakamoto, S; Takishita, E1
Klein, RL; Lopes-Virella, MF; Lyons, TJ1
Chen, YD; Kraemer, FB; Lopez, RD; Reaven, GM1

Reviews

2 review(s) available for oleic acid and Diabetes Mellitus, Type 2

ArticleYear
Current perspectives of oleic acid: Regulation of molecular pathways in mitochondrial and endothelial functioning against insulin resistance and diabetes.
    Reviews in endocrine & metabolic disorders, 2020, Volume: 21, Issue:4

    Topics: Diabetes Mellitus, Type 2; Endothelium, Vascular; Humans; Insulin Resistance; Mitochondria; Oleic Acid

2020
Palmitic and Oleic Acid: The Yin and Yang of Fatty Acids in Type 2 Diabetes Mellitus.
    Trends in endocrinology and metabolism: TEM, 2018, Volume: 29, Issue:3

    Topics: Animals; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Insulin-Secreting Cells; Oleic Acid; Palmitic Acid

2018

Trials

9 trial(s) available for oleic acid and Diabetes Mellitus, Type 2

ArticleYear
Comparing olive oil and C4-dietary oil, a prodrug for the GPR119 agonist, 2-oleoyl glycerol, less energy intake of the latter is needed to stimulate incretin hormone secretion in overweight subjects with type 2 diabetes.
    Nutrition & diabetes, 2018, 01-12, Volume: 8, Issue:1

    Topics: Aged; Area Under Curve; Diabetes Mellitus, Type 2; Dietary Fats, Unsaturated; Female; Gastric Inhibitory Polypeptide; Glucagon-Like Peptide 1; Glycerides; Glycerol; Humans; Incretins; Male; Meals; Middle Aged; Obesity; Oleic Acid; Olive Oil; Overweight; Postprandial Period; Prodrugs; Receptors, G-Protein-Coupled; Single-Blind Method; Triglycerides

2018
Abnormal Glucose Tolerance Is Associated with a Reduced Myocardial Metabolic Flexibility in Patients with Dilated Cardiomyopathy.
    Journal of diabetes research, 2016, Volume: 2016

    Topics: Aged; Biomarkers; Blood Flow Velocity; Blood Glucose; Cardiac Pacing, Artificial; Cardiomyopathy, Dilated; Case-Control Studies; Coronary Circulation; Diabetes Mellitus, Type 2; Energy Metabolism; Fatty Acids, Nonesterified; Female; Glucose Intolerance; Humans; Lactic Acid; Male; Middle Aged; Myocardium; Oleic Acid; Oxidation-Reduction; Oxygen; Ventricular Function, Left

2016
Paraoxonase 1 activity in chylomicrons and VLDL: the effect of type 2 diabetes and meals rich in saturated fat and oleic acid.
    Lipids, 2012, Volume: 47, Issue:3

    Topics: Aged; Aryldialkylphosphatase; Chylomicrons; Cross-Over Studies; Diabetes Mellitus, Type 2; Dietary Fats; Female; Humans; Lipoproteins, VLDL; Male; Middle Aged; Oleic Acid

2012
Lipid, glycemic, and insulin responses to meals rich in saturated, cis-monounsaturated, and polyunsaturated (n-3 and n-6) fatty acids in subjects with type 2 diabetes.
    Diabetes care, 2007, Volume: 30, Issue:12

    Topics: Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 2; Diet, Diabetic; Dietary Fats; Docosahexaenoic Acids; Eicosapentaenoic Acid; Humans; Hypoglycemic Agents; Insulin; Linoleic Acid; Lipids; Male; Oleic Acid

2007
Effects of insulin therapy upon plasma lipid fatty acids and platelet aggregation in NIDDM with secondary failure to oral antidiabetic agents.
    Diabetes research and clinical practice, 1995, Volume: 28, Issue:1

    Topics: Adenosine Diphosphate; Administration, Oral; Adult; Aged; Blood Glucose; Body Mass Index; Cholesterol Esters; Diabetes Mellitus, Type 2; Fatty Acids; Fatty Acids, Nonesterified; Fatty Acids, Unsaturated; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Linoleic Acid; Linoleic Acids; Middle Aged; Oleic Acid; Oleic Acids; Phospholipids; Platelet Aggregation; Time Factors; Treatment Failure; Triglycerides

1995
Dietary unsaturated fatty acids in type 2 diabetes: higher levels of postprandial lipoprotein on a linoleic acid-rich sunflower oil diet compared with an oleic acid-rich olive oil diet.
    Diabetes care, 2000, Volume: 23, Issue:10

    Topics: Apolipoprotein B-48; Apolipoproteins B; Arteriosclerosis; Blood Glucose; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cross-Over Studies; Diabetes Mellitus, Type 2; Dietary Fats, Unsaturated; Energy Intake; Humans; Lipoproteins; Male; Middle Aged; Oleic Acid; Olive Oil; Plant Oils; Postprandial Period; Triglycerides

2000
Diet-induced change in fatty acid composition of plasma triacylglycerols is not associated with change in glucagon-like peptide 1 or insulin sensitivity in people with type 2 diabetes.
    The American journal of clinical nutrition, 2000, Volume: 72, Issue:5

    Topics: Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 2; Dietary Fats, Unsaturated; Double-Blind Method; Fatty Acids; Fatty Acids, Monounsaturated; Fatty Acids, Nonesterified; Fatty Acids, Unsaturated; Glucagon; Glucagon-Like Peptide 1; Humans; Insulin; Linoleic Acid; Oleic Acid; Peptide Fragments; Protein Precursors; Triglycerides

2000
Supplementation with long-chain n-3 fatty acids in non-insulin-dependent diabetes mellitus (NIDDM) patients leads to the lowering of oleic acid content in serum phospholipids.
    European journal of nutrition, 2000, Volume: 39, Issue:5

    Topics: Cardiovascular Diseases; Diabetes Mellitus, Type 2; Dietary Supplements; Docosahexaenoic Acids; Drug Combinations; Eicosapentaenoic Acid; Female; Humans; Male; Middle Aged; Oleic Acid; Olive Oil; Phospholipids; Plant Oils

2000
Effect of a low-fat diet enriched with oleic acid on postprandial lipemia in patients with type 2 diabetes mellitus.
    Lipids, 2001, Volume: 36, Issue:1

    Topics: Aged; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cross-Over Studies; Diabetes Mellitus, Type 2; Diet, Fat-Restricted; Dietary Fats, Unsaturated; Energy Intake; Exercise; Fasting; Female; Food; Humans; Linoleic Acid; Lipid Peroxidation; Lipids; Lipoproteins, LDL; Male; Middle Aged; Oleic Acid; Postmenopause; Triglycerides

2001

Other Studies

63 other study(ies) available for oleic acid and Diabetes Mellitus, Type 2

ArticleYear
The Different Insulin-Sensitising and Anti-Inflammatory Effects of Palmitoleic Acid and Oleic Acid in a Prediabetes Model.
    Journal of diabetes research, 2022, Volume: 2022

    Topics: Adiponectin; Animals; Anti-Inflammatory Agents; Arachidonic Acids; Cytokines; Diabetes Mellitus, Type 2; Fatty Acids; Fatty Acids, Monounsaturated; Fatty Acids, Nonesterified; Glucagon; Glucose; Inflammation; Insulin; Insulin Resistance; Lipoprotein Lipase; Oleic Acid; Prediabetic State; Rats

2022
Single-Cell RNA Sequencing Reveals a Role for Reactive Oxygen Species and Peroxiredoxins in Fatty Acid-Induced Rat β-Cell Proliferation.
    Diabetes, 2023, 01-01, Volume: 72, Issue:1

    Topics: Animals; Cell Proliferation; Diabetes Mellitus, Type 2; Fatty Acids; Glucose; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Oleic Acid; Palmitates; Rats; Reactive Oxygen Species; Sequence Analysis, RNA

2023
Hepatic oleate regulates one-carbon metabolism during high carbohydrate feeding.
    Biochemical and biophysical research communications, 2023, 04-09, Volume: 651

    Topics: Animals; Carbohydrates; Carbon; Diabetes Mellitus, Type 2; Liver; Mice; Mice, Knockout; Obesity; Oleic Acid; Phosphatidylethanolamine N-Methyltransferase; S-Adenosylmethionine

2023
Identification of a subset of trace amine-associated receptors and ligands as potential modulators of insulin secretion.
    Biochemical pharmacology, 2020, Volume: 171

    Topics: Animals; Cell Line, Tumor; Diabetes Mellitus, Type 2; Gene Expression Profiling; Glucose; Humans; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Islets of Langerhans; Ligands; Male; Mice; Oleic Acid; Palmitic Acid; Rats; Receptors, G-Protein-Coupled

2020
Treatment of insulin resistance in obesity-associated type 2 diabetes mellitus through adiponectin gene therapy.
    International journal of pharmaceutics, 2020, Jun-15, Volume: 583

    Topics: 3T3-L1 Cells; Adiponectin; Animals; Chitosan; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Genetic Therapy; Insulin Resistance; Male; Mice; Nanoparticles; Obesity; Oleic Acid; Peptides; Plasmids; Rats, Wistar

2020
Lipotoxicity dysregulates the immunoproteasome in podocytes and kidneys in type 2 diabetes.
    American journal of physiology. Renal physiology, 2021, 04-01, Volume: 320, Issue:4

    Topics: Animals; Apoptosis; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Eicosapentaenoic Acid; Glucose; Hydrogen Peroxide; Kidney; Mice; Oleic Acid; Oxidative Stress; Podocytes

2021
Loss of Stearoyl-CoA desaturase 1 leads to cardiac dysfunction and lipotoxicity.
    The Journal of experimental biology, 2021, 09-15, Volume: 224, Issue:18

    Topics: Animals; Diabetes Mellitus, Type 2; Drosophila melanogaster; Fatty Acids; Heart Diseases; Oleic Acid; Stearoyl-CoA Desaturase

2021
Autophagy plays beneficial effect on diabetic encephalopathy in type 2 diabetes: studies in vivo and in vitro.
    Neuro endocrinology letters, 2017, Volume: 38, Issue:1

    Topics: Adenine; Animals; Arcuate Nucleus of Hypothalamus; Autophagy; Blotting, Western; Brain Diseases; Cholesterol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Down-Regulation; Glucose Tolerance Test; Hypothalamus; Immunosuppressive Agents; In Vitro Techniques; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Lipid Metabolism; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Neurons; Oleic Acid; PC12 Cells; Rats; Receptor, Insulin; Sirolimus; TOR Serine-Threonine Kinases; Up-Regulation; Ventromedial Hypothalamic Nucleus

2017
Quercetin/oleic acid-based G-protein-coupled receptor 40 ligands as new insulin secretion modulators.
    Future medicinal chemistry, 2017, Volume: 9, Issue:16

    Topics: Animals; Benzopyrans; Cell Line; Computer Simulation; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Insulin; Ligands; Male; Mice; Mice, Inbred C57BL; Oleic Acid; Pancreas; Quercetin; Receptors, G-Protein-Coupled

2017
Oleic acid increases the transcriptional activity of FoxO1 by promoting its nuclear translocation and β-catenin binding in pancreatic β-cells.
    Biochimica et biophysica acta. Molecular basis of disease, 2019, 10-01, Volume: 1865, Issue:10

    Topics: Animals; beta Catenin; Cell Nucleus; Diabetes Mellitus, Type 2; Forkhead Box Protein O1; Gene Expression Regulation; Homeodomain Proteins; Insulin-Secreting Cells; Male; Nerve Tissue Proteins; Oleic Acid; Protein Transport; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Stearoyl-CoA Desaturase; Trans-Activators; Transcription Factor 7-Like 2 Protein

2019
VEGF in the crosstalk between human adipocytes and smooth muscle cells: depot-specific release from visceral and perivascular adipose tissue.
    Mediators of inflammation, 2013, Volume: 2013

    Topics: Adipocytes; Adipokines; Adipose Tissue; Adult; Biopsy; Cell Proliferation; Cells, Cultured; Coronary Vessels; Diabetes Mellitus, Type 2; Female; Gene Expression Regulation; Humans; Inflammation; Intra-Abdominal Fat; Male; Middle Aged; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Obesity; Oleic Acid; Overweight; Vascular Endothelial Growth Factor A; Young Adult

2013
Opposite regulation of hepatic breast cancer resistance protein in type 1 and 2 diabetes mellitus.
    European journal of pharmacology, 2014, Feb-05, Volume: 724

    Topics: Adult; Aged; Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Bile; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Fluorobenzenes; Glucose; Hepatocytes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin; Liver; Liver Neoplasms; Male; Middle Aged; Neoplasm Proteins; Oleic Acid; Pyrimidines; Rats; Rats, Wistar; RNA, Messenger; Rosuvastatin Calcium; Sulfonamides

2014
Clustering effects on postprandial insulin secretion and sensitivity in response to meals with different fatty acid compositions.
    Food & function, 2014, Jul-25, Volume: 5, Issue:7

    Topics: Adult; Blood Glucose; Body Mass Index; Cluster Analysis; Diabetes Mellitus, Type 2; Diet; Dietary Fats; Fatty Acids, Unsaturated; Healthy Volunteers; Humans; Hyperlipoproteinemias; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Male; Meals; Oleic Acid; Palmitic Acid; Postprandial Period; Triglycerides

2014
Serum phospholipid monounsaturated fatty acid composition and Δ-9-desaturase activity are associated with early alteration of fasting glycemic status.
    Nutrition research (New York, N.Y.), 2014, Volume: 34, Issue:9

    Topics: 8,11,14-Eicosatrienoic Acid; Biomarkers; Blood Glucose; C-Reactive Protein; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Dinoprost; Fasting; Fatty Acids, Monounsaturated; Female; Humans; Insulin; Insulin Resistance; Linoleic Acid; Lipoproteins, LDL; Male; Metabolic Syndrome; Middle Aged; Oleic Acid; Phospholipids; Stearoyl-CoA Desaturase; Triglycerides

2014
Increased pyruvate dehydrogenase kinase expression in cultured myotubes from obese and diabetic individuals.
    European journal of nutrition, 2015, Volume: 54, Issue:7

    Topics: Adult; Blood Glucose; Body Mass Index; Body Weight; Cells, Cultured; Cholesterol; Diabetes Mellitus, Type 2; Eicosapentaenoic Acid; Female; Gene Expression Regulation; Humans; Insulin; Male; Middle Aged; Muscle Fibers, Skeletal; Obesity; Oleic Acid; Palmitic Acid; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; RNA, Messenger; Triglycerides

2015
Polyphenol fraction of extra virgin olive oil protects against endothelial dysfunction induced by high glucose and free fatty acids through modulation of nitric oxide and endothelin-1.
    Redox biology, 2014, Volume: 2

    Topics: Cell Line; Diabetes Mellitus, Type 2; Endothelial Cells; Endothelin-1; Fatty Acids, Nonesterified; Glucose; Linoleic Acid; Nitric Oxide; Nitric Oxide Synthase Type III; Oleic Acid; Olive Oil; Polyphenols

2014
Metformin alleviates hepatosteatosis by restoring SIRT1-mediated autophagy induction via an AMP-activated protein kinase-independent pathway.
    Autophagy, 2015, Volume: 11, Issue:1

    Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Blood Glucose; Body Weight; Caloric Restriction; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus, Type 2; Down-Regulation; Fatty Liver; Hep G2 Cells; Hepatocytes; Humans; Lipid Metabolism; Liver; Metformin; Mice, Inbred C57BL; Mice, Obese; Models, Biological; Oleic Acid; Phagosomes; Signal Transduction; Sirtuin 1; Up-Regulation

2015
Myotubes from severely obese type 2 diabetic subjects accumulate less lipids and show higher lipolytic rate than myotubes from severely obese non-diabetic subjects.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: Diabetes Mellitus, Type 2; Energy Metabolism; Fatty Acids; Humans; Lipase; Lipid Metabolism; Lipolysis; Membrane Proteins; Muscle Fibers, Skeletal; Obesity; Oleic Acid; Oxidation-Reduction; Perilipin-2; Perilipin-3; Phosphorylation; Proto-Oncogene Proteins c-akt; Severity of Illness Index; Triglycerides; Vesicular Transport Proteins

2015
Primary defects in lipolysis and insulin action in skeletal muscle cells from type 2 diabetic individuals.
    Biochimica et biophysica acta, 2015, Volume: 1851, Issue:9

    Topics: Biological Transport; Carbon Radioisotopes; Diabetes Mellitus, Type 2; Diglycerides; Female; Gene Expression Regulation; Glycerol; Glycogen; Humans; Insulin; Lipolysis; Male; Middle Aged; Muscle Fibers, Skeletal; Obesity; Oleic Acid; Primary Cell Culture; Proto-Oncogene Proteins c-akt; Signal Transduction; Sterol Esterase

2015
Hepatic scavenger receptor BI is associated with type 2 diabetes but unrelated to human and murine non-alcoholic fatty liver disease.
    Biochemical and biophysical research communications, 2015, Nov-13, Volume: 467, Issue:2

    Topics: Adiponectin; Adult; Aged; Aged, 80 and over; Animals; Chemokines; Cytokines; Diabetes Mellitus, Type 2; Female; Gene Expression Regulation; GPI-Linked Proteins; Hepatocytes; Humans; Intercellular Signaling Peptides and Proteins; Lectins; Leptin; Lipopolysaccharides; Lipoproteins, HDL; Liver; Male; Mice; Middle Aged; Non-alcoholic Fatty Liver Disease; Oleic Acid; Palmitic Acid; Primary Cell Culture; Scavenger Receptors, Class B; Signal Transduction; Transforming Growth Factor beta

2015
Identification of Novel Genetic Determinants of Erythrocyte Membrane Fatty Acid Composition among Greenlanders.
    PLoS genetics, 2016, Volume: 12, Issue:6

    Topics: Body Size; Carnitine O-Palmitoyltransferase; Coenzyme A Ligases; Diabetes Mellitus, Type 2; Docosahexaenoic Acids; Erythrocyte Membrane; Fatty Acids; Fatty Acids, Monounsaturated; Female; Genetic Loci; Genotype; Glycated Hemoglobin; Greenland; Humans; Insulin; Insulin Resistance; Male; Oleic Acid; Phospholipids; Polymorphism, Single Nucleotide

2016
A panel of free fatty acid ratios to predict the development of metabolic abnormalities in healthy obese individuals.
    Scientific reports, 2016, 06-27, Volume: 6

    Topics: 8,11,14-Eicosatrienoic Acid; Adult; Arachidonic Acid; Area Under Curve; Body Mass Index; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diet; Fatty Acids, Nonesterified; Female; Humans; Logistic Models; Longitudinal Studies; Male; Middle Aged; Obesity; Oleic Acid; Palmitic Acid; Retrospective Studies; ROC Curve; Stearic Acids

2016
Metabolic signatures and risk of type 2 diabetes in a Chinese population: an untargeted metabolomics study using both LC-MS and GC-MS.
    Diabetologia, 2016, Volume: 59, Issue:11

    Topics: Amino Acids, Branched-Chain; Asian People; Blood Glucose; Case-Control Studies; Chromatography, Liquid; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Furans; Gas Chromatography-Mass Spectrometry; Glycated Hemoglobin; Glycerol; Humans; Linoleic Acid; Lysophospholipids; Metabolomics; Oleic Acid; Proline; Propionates; Urea

2016
Diabetic Risk Factors Promote Islet Amyloid Polypeptide Misfolding by a Common, Membrane-mediated Mechanism.
    Scientific reports, 2016, 08-17, Volume: 6

    Topics: Circular Dichroism; Diabetes Mellitus, Type 2; Humans; Islet Amyloid Polypeptide; Membranes; Microscopy, Electron; Obesity; Oleic Acid; Optical Imaging; Phosphatidic Acids; Phthalic Acids; Protein Folding

2016
Fatty acid incubation of myotubes from humans with type 2 diabetes leads to enhanced release of beta-oxidation products because of impaired fatty acid oxidation: effects of tetradecylthioacetic acid and eicosapentaenoic acid.
    Diabetes, 2009, Volume: 58, Issue:3

    Topics: Carbon Dioxide; Carbon Radioisotopes; Carnitine O-Palmitoyltransferase; Diabetes Mellitus, Type 2; Eicosapentaenoic Acid; Fatty Acid Binding Protein 3; Fatty Acid-Binding Proteins; Fatty Acids; Glucose; Humans; Insulin; Ion Channels; Lipids; Mitochondrial Proteins; Muscle Fibers, Skeletal; Myoblasts; Oleic Acid; Oxidation-Reduction; Palmitic Acid; Reference Values; Reverse Transcriptase Polymerase Chain Reaction; Sulfides; Uncoupling Protein 2

2009
Effects of palmitate on ER and cytosolic Ca2+ homeostasis in beta-cells.
    American journal of physiology. Endocrinology and metabolism, 2009, Volume: 296, Issue:4

    Topics: Animals; Calcium; Calcium Signaling; Cell Death; Cells, Cultured; Cytosol; Diabetes Mellitus, Type 2; Endoplasmic Reticulum; Fatty Acids, Nonesterified; Homeostasis; Humans; Insulin; Insulin Secretion; Insulin-Secreting Cells; Mice; Oleic Acid; Palmitic Acid

2009
Oleic acid and peanut oil high in oleic acid reverse the inhibitory effect of insulin production of the inflammatory cytokine TNF-alpha both in vitro and in vivo systems.
    Lipids in health and disease, 2009, Jun-26, Volume: 8

    Topics: Animals; Apoptosis; Blood Glucose; Cell Line; Cyclic AMP; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Inflammation Mediators; Insulin; Intracellular Space; Mice; Oleic Acid; Peanut Oil; Plant Oils; PPAR gamma; Protein Transport; Rats; Tumor Necrosis Factor-alpha

2009
Regulation of skeletal muscle sucrose, non-fermenting 1/AMP-activated protein kinase-related kinase (SNARK) by metabolic stress and diabetes.
    Diabetologia, 2009, Volume: 52, Issue:10

    Topics: Cells, Cultured; Diabetes Mellitus, Type 2; Female; Gene Expression; Glucose; Humans; Interleukin-6; Lipid Metabolism; Male; Middle Aged; Muscle Fibers, Skeletal; Muscle, Skeletal; Obesity; Oleic Acid; Palmitic Acid; Protein Serine-Threonine Kinases; RNA, Small Interfering; Tumor Necrosis Factor-alpha

2009
Sterol regulatory element-binding protein-1c knockdown protected INS-1E cells from lipotoxicity.
    Diabetes, obesity & metabolism, 2010, Volume: 12, Issue:1

    Topics: Animals; Apoptosis; Blotting, Western; Cell Line; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Gene Expression; Gene Knockdown Techniques; Glucose; Humans; Insulin; Insulin Secretion; Insulin-Secreting Cells; Lipid Metabolism; Oleic Acid; Palmitates; RNA, Small Interfering; Sterol Regulatory Element Binding Protein 1; Transcription, Genetic; Triglycerides; Up-Regulation

2010
Adiponectin downregulates galectin-3 whose cellular form is elevated whereas its soluble form is reduced in type 2 diabetic monocytes.
    FEBS letters, 2009, Nov-19, Volume: 583, Issue:22

    Topics: Adiponectin; Adult; Aged; Aged, 80 and over; Aminoimidazole Carboxamide; Body Mass Index; Cells, Cultured; Cholesterol; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Galectin 3; Humans; Immunoblotting; Male; Metformin; Middle Aged; Monocytes; Oleic Acid; Palmitic Acid; Pyrazoles; Pyrimidines; Reverse Transcriptase Polymerase Chain Reaction; Ribonucleotides; Solubility; Time Factors

2009
Palmitate-induced changes in protein expression of insulin secreting INS-1E cells.
    Journal of proteomics, 2010, Apr-18, Volume: 73, Issue:6

    Topics: Diabetes Mellitus, Type 2; Electrophoresis, Gel, Two-Dimensional; Gene Expression Regulation; Glycolysis; Humans; Image Processing, Computer-Assisted; Insulin-Secreting Cells; Mass Spectrometry; Models, Biological; Oleic Acid; Palmitates; Palmitic Acid; Proteomics; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2010
Oxidation of intramyocellular lipids is dependent on mitochondrial function and the availability of extracellular fatty acids.
    American journal of physiology. Endocrinology and metabolism, 2010, Volume: 299, Issue:1

    Topics: Adult; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cross-Over Studies; Diabetes Mellitus, Type 2; Fatty Acids; Female; Glucose; Humans; Male; Microscopy, Fluorescence; Middle Aged; Mitochondria, Muscle; Muscle Fibers, Skeletal; Muscle, Skeletal; Obesity; Oleic Acid; Statistics, Nonparametric; Uncoupling Agents

2010
Oleate blocks palmitate-induced abnormal lipid distribution, endoplasmic reticulum expansion and stress, and insulin resistance in skeletal muscle.
    Endocrinology, 2011, Volume: 152, Issue:6

    Topics: Animals; Cell Line; Diabetes Mellitus, Type 2; Down-Regulation; Endoplasmic Reticulum; Humans; Insulin; Insulin Resistance; Lipid Metabolism; Male; Mice; Muscle, Skeletal; Oleic Acid; Oxidative Stress; Palmitates; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction

2011
Decreased expression of endoplasmic reticulum chaperone GRP78 in liver of diabetic mice.
    Biochemical and biophysical research communications, 2012, Jan-06, Volume: 417, Issue:1

    Topics: Animals; Diabetes Mellitus, Type 2; Down-Regulation; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Heat-Shock Proteins; Hep G2 Cells; Hepatocytes; Humans; Insulin; Insulin Resistance; Liver; Male; Mice; Oleic Acid; Protein Disulfide-Isomerases; Proteomics; Proto-Oncogene Proteins c-akt; RNA, Messenger; Transcription, Genetic

2012
GLP1-derived nonapeptide GLP1(28-36)amide protects pancreatic β-cells from glucolipotoxicity.
    The Journal of endocrinology, 2012, Volume: 213, Issue:2

    Topics: Adenosine Triphosphate; Apoptosis; Cell Survival; Cells, Cultured; Diabetes Mellitus, Type 2; Exenatide; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucose; Humans; Hydrogen Peroxide; Insulin; Insulin Secretion; Insulin-Secreting Cells; Membrane Potential, Mitochondrial; Oleic Acid; Oxidative Stress; Peptide Fragments; Peptides; Receptors, Glucagon; tert-Butylhydroperoxide; Venoms

2012
Solute carrier family 2 member 1 is involved in the development of nonalcoholic fatty liver disease.
    Hepatology (Baltimore, Md.), 2013, Volume: 57, Issue:2

    Topics: Adolescent; Adult; Aged; Diabetes Mellitus, Type 2; Fatty Liver; Female; Gene Frequency; Gene Silencing; Genetic Predisposition to Disease; Glucose Transporter Type 1; Humans; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Oleic Acid; Oxidative Stress; Polymorphism, Single Nucleotide; Transcriptome

2013
Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortiu
    Circulation. Cardiovascular genetics, 2013, Volume: 6, Issue:2

    Topics: Adult; Aged; Chromosomes, Human, Pair 2; Cohort Studies; Coronary Disease; Delta-5 Fatty Acid Desaturase; Diabetes Mellitus, Type 2; Fatty Acids, Monounsaturated; Female; Genetic Loci; Genome-Wide Association Study; Genotype; Humans; Linkage Disequilibrium; Lipogenesis; Male; Middle Aged; Oleic Acid; Palmitic Acid; Polymorphism, Single Nucleotide; Stearic Acids

2013
Long-chain CoA esters activate human pancreatic beta-cell KATP channels: potential role in Type 2 diabetes.
    Diabetologia, 2004, Volume: 47, Issue:2

    Topics: Acyl Coenzyme A; Adenosine Diphosphate; Adenosine Triphosphate; Diabetes Mellitus, Type 2; Diazoxide; Dose-Response Relationship, Drug; Glucose; Humans; Islets of Langerhans; Kinetics; Magnesium Chloride; Membrane Potentials; Membrane Proteins; Oleic Acid; Palmitoyl Coenzyme A; Patch-Clamp Techniques; Potassium Channels

2004
Differential utilization of saturated palmitate and unsaturated oleate: evidence from cultured myotubes.
    Diabetes, 2005, Volume: 54, Issue:3

    Topics: Diabetes Mellitus, Type 2; Glucose; Humans; In Vitro Techniques; Insulin; Lipid Metabolism; Male; Middle Aged; Muscle Fibers, Skeletal; Oleic Acid; Oxidation-Reduction; Palmitic Acid

2005
Mechanisms of oleic acid deterioration in insulin secretion: role in the pathogenesis of type 2 diabetes.
    Life sciences, 2005, Sep-09, Volume: 77, Issue:17

    Topics: Animals; Blotting, Western; Calcium; Cells, Cultured; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Glucose Transporter Type 2; Homeodomain Proteins; Insulin; Insulin Secretion; Islets of Langerhans; Male; Monosaccharide Transport Proteins; Oleic Acid; Proinsulin; Protein Precursors; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Trans-Activators

2005
Free fatty acids repress the GLUT4 gene expression in cardiac muscle via novel response elements.
    The Journal of biological chemistry, 2005, Oct-14, Volume: 280, Issue:41

    Topics: Aged; Animals; Arachidonic Acid; Biopsy; Blotting, Western; Cell Nucleus; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Deoxyglucose; Diabetes Mellitus, Type 2; DNA; DNA Primers; Dose-Response Relationship, Drug; Fatty Acids; Female; Gene Deletion; Gene Expression Regulation; Genes, Reporter; Glucose Transporter Type 4; HeLa Cells; Humans; Linoleic Acid; Lipids; Male; Middle Aged; Models, Biological; Muscles; Myocardium; Oleic Acid; PPAR gamma; Promoter Regions, Genetic; Protein Binding; Proteins; Rats; Response Elements; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stearic Acids; Time Factors; Transcription, Genetic

2005
Serum fatty acids in postinfarction middle-aged men.
    Scandinavian journal of clinical and laboratory investigation, 2005, Volume: 65, Issue:6

    Topics: Aged; Body Mass Index; Cholesterol, HDL; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Dietary Fats; Fatty Acids; Finland; Humans; Linoleic Acid; Male; Metabolic Syndrome; Middle Aged; Myocardial Infarction; Oleic Acid; Palmitic Acid; Triglycerides

2005
PPARGC1A mRNA levels of in vitro differentiated human skeletal muscle cells are negatively associated with the plasma oleate concentrations of the donors.
    Diabetologia, 2006, Volume: 49, Issue:1

    Topics: Base Sequence; Cell Differentiation; Diabetes Mellitus, Type 2; DNA Primers; Gene Expression Regulation; Heat-Shock Proteins; Humans; Insulin Resistance; Muscle, Skeletal; Oleic Acid; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Reference Values; RNA, Messenger; Transcription Factors

2006
Pro12Ala polymorphism of the PPARG2 gene is associated with type 2 diabetes mellitus and peripheral insulin sensitivity in a population with a high intake of oleic acid.
    The Journal of nutrition, 2006, Volume: 136, Issue:9

    Topics: Adolescent; Adult; Aged; Alanine; Alleles; Body Mass Index; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Dietary Fats, Unsaturated; Energy Intake; Fatty Acids, Monounsaturated; Glucose Tolerance Test; Homeostasis; Humans; Insulin Resistance; Logistic Models; Middle Aged; Obesity; Odds Ratio; Oleic Acid; Olive Oil; Plant Oils; Polymorphism, Genetic; PPAR gamma; Spain

2006
Obesity increases free thyroxine proportionally to nonesterified fatty acid concentrations in adult neutered female cats.
    The Journal of endocrinology, 2007, Volume: 194, Issue:2

    Topics: Animals; Cats; Diabetes Mellitus, Type 2; Disease Progression; Fatty Acids, Nonesterified; Female; Insulin Resistance; Leptin; Models, Animal; Obesity; Oleic Acid; Ovariectomy; Palmitic Acid; Thyrotropin; Thyroxine; Triiodothyronine

2007
Free fatty acid-induced reduction in glucose-stimulated insulin secretion: evidence for a role of oxidative stress in vitro and in vivo.
    Diabetes, 2007, Volume: 56, Issue:12

    Topics: Acetylcysteine; Animals; Antioxidants; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Female; Glucose; Infusions, Intravenous; Insulin; Insulin Secretion; Obesity; Oleic Acid; Oxidative Stress; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Taurine

2007
Simultaneously quantitative measurement of comprehensive profiles of esterified and non-esterified fatty acid in plasma of type 2 diabetic patients.
    Chemistry and physics of lipids, 2007, Volume: 150, Issue:2

    Topics: Adult; Aged; Calibration; Chromatography, Thin Layer; Diabetes Mellitus, Type 2; Esters; Fatty Acids; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Methylation; Middle Aged; Multivariate Analysis; Oleic Acid; Reproducibility of Results; Rosiglitazone; Thiazolidinediones; Time Factors

2007
Effects of ethanol on pancreatic beta-cell death: interaction with glucose and fatty acids.
    Cell biology and toxicology, 2009, Volume: 25, Issue:2

    Topics: Animals; Apoptosis; Cell Line; Central Nervous System Depressants; Diabetes Mellitus, Type 2; Drug Interactions; Ethanol; Glucose; Insulin-Secreting Cells; Mitochondria; Oleic Acid; Oxidative Stress; Palmitic Acid; Rats

2009
Effects of non-esterified fatty acids on insulin-stimulated glucose transport in isolated skeletal muscle from patients with type 2 (non-insulin-dependent) diabetes mellitus.
    Acta diabetologica, 1994, Volume: 31, Issue:3

    Topics: 3-O-Methylglucose; Biological Transport; Biopsy; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Female; Humans; In Vitro Techniques; Insulin; Male; Methylglucosides; Middle Aged; Muscle, Skeletal; Oleic Acid; Oleic Acids; Reference Values

1994
Impaired free fatty acid utilization by skeletal muscle in non-insulin-dependent diabetes mellitus.
    The Journal of clinical investigation, 1994, Volume: 94, Issue:6

    Topics: Blood Glucose; Calorimetry, Indirect; Diabetes Mellitus, Type 2; Fasting; Fatty Acids, Nonesterified; Female; Humans; Hyperglycemia; Insulin; Leg; Male; Middle Aged; Models, Biological; Muscle Fibers, Skeletal; Muscle, Skeletal; Oleic Acid; Oleic Acids; Oxidation-Reduction; Triglycerides

1994
Non-insulin-dependent diabetes mellitus: dietary monounsaturated fatty acids and low-density lipoprotein composition and function.
    QJM : monthly journal of the Association of Physicians, 1996, Volume: 89, Issue:3

    Topics: Acetates; Adult; Arachidonic Acid; Arteriosclerosis; Blood Glucose; Cholesterol; Diabetes Mellitus, Type 2; Fasting; Female; Humans; Linoleic Acid; Linoleic Acids; Lipoproteins, LDL; Male; Middle Aged; Oleic Acid; Oleic Acids

1996
Lipoprotein composition in NIDDM: effects of dietary oleic acid on the composition, oxidisability and function of low and high density lipoproteins.
    Diabetologia, 1996, Volume: 39, Issue:6

    Topics: Adult; Aged; Cholesterol; Chromatography, Gas; Diabetes Mellitus, Type 2; Diet, Fat-Restricted; Dietary Fats, Unsaturated; Fasting; Fatty Acids; Female; Humans; Lipid Peroxides; Lipoproteins, HDL; Lipoproteins, LDL; Male; Middle Aged; Odds Ratio; Oleic Acid; Oxidation-Reduction; Reagent Kits, Diagnostic; Time Factors; Triglycerides; Vitamin E

1996
Remnant-like particles (RLP) from NIDDM patients with apolipoprotein E3/3 phenotype stimulate cholesteryl ester synthesis in human monocyte-derived macrophages.
    Artery, 1996, Volume: 22, Issue:3

    Topics: Antibodies, Monoclonal; Apolipoprotein A-I; Apolipoprotein B-100; Apolipoprotein E3; Apolipoproteins B; Apolipoproteins E; Cells, Cultured; Cholesterol; Cholesterol Esters; Cholesterol, HDL; Chromatography, Affinity; Diabetes Mellitus, Type 2; Female; Genotype; Humans; Macrophages; Male; Monocytes; Oleic Acid; Phenotype; Reference Values; Triglycerides

1996
Uptake of long chain free fatty acids is selectively up-regulated in adipocytes of Zucker rats with genetic obesity and non-insulin-dependent diabetes mellitus.
    The Journal of biological chemistry, 1997, Mar-28, Volume: 272, Issue:13

    Topics: Adipocytes; Aging; Animals; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Glucose; Leptin; Lipoprotein Lipase; Liver; Male; Myocardium; Obesity; Oleic Acid; Protein Biosynthesis; Rats; Rats, Zucker; RNA, Messenger; Tumor Necrosis Factor-alpha; Up-Regulation; Weaning

1997
Regulated membrane transport of free fatty acids in adipocytes: role in obesity and non-insulin dependent diabetes mellitus.
    Transactions of the American Clinical and Climatological Association, 1997, Volume: 108

    Topics: Adipose Tissue; Animals; Biological Transport, Active; Carrier Proteins; Cell Membrane; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Humans; In Vitro Techniques; Kinetics; Liver; Male; Myocardium; Obesity; Oleic Acid; Rats; Rats, Wistar; Rats, Zucker; RNA, Messenger; Tumor Necrosis Factor-alpha

1997
Structural and compositional modifications of diabetic low-density lipoproteins influence their receptor-mediated uptake by hepatocytes.
    European journal of clinical investigation, 1997, Volume: 27, Issue:6

    Topics: Acetic Acid; Aged; Arteriosclerosis; Biological Transport, Active; Cell Line; Cholesterol Esters; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glycosylation; Humans; Lipoproteins, LDL; Liver; Male; Middle Aged; Oleic Acid; Oxidation-Reduction; Protein Conformation; Receptors, LDL; Sterols

1997
Chronic exposure to free fatty acid reduces pancreatic beta cell insulin content by increasing basal insulin secretion that is not compensated for by a corresponding increase in proinsulin biosynthesis translation.
    The Journal of clinical investigation, 1998, Mar-01, Volume: 101, Issue:5

    Topics: Animals; Anticoagulants; Cells, Cultured; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Gene Expression Regulation; Glucose; Heparin; Hormone Antagonists; Insulin; Insulin Secretion; Islets of Langerhans; Male; Oils; Oleic Acid; Pancreas; Pharmaceutic Aids; Proinsulin; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; RNA, Messenger; Somatostatin

1998
Long-chain fatty acids and cardiovascular disease risk in non-insulin-dependent diabetes.
    Nutrition (Burbank, Los Angeles County, Calif.), 1998, Volume: 14, Issue:3

    Topics: Cardiovascular Diseases; Diabetes Mellitus, Type 2; Dietary Fats; Dietary Fats, Unsaturated; Fatty Acids; Humans; Linoleic Acid; Oleic Acid; Risk Factors

1998
Diabetes and the Mediterranean diet: a beneficial effect of oleic acid on insulin sensitivity, adipocyte glucose transport and endothelium-dependent vasoreactivity.
    QJM : monthly journal of the Association of Physicians, 2000, Volume: 93, Issue:2

    Topics: Adipocytes; Adult; Aged; Biological Transport; Diabetes Mellitus, Type 2; Diet; Endothelium, Vascular; Fatty Acids; Glucose; Humans; Insulin; Male; Membrane Lipids; Middle Aged; Oleic Acid; Vasodilation

2000
Dehydroepiandrosterone alters phospholipid profiles in Zucker rat muscle tissue.
    Lipids, 2001, Volume: 36, Issue:12

    Topics: Animals; Arachidonic Acid; Dehydroepiandrosterone; Diabetes Mellitus, Type 2; Fatty Acids; Heart; Insulin Resistance; Muscle, Skeletal; Myocardium; Obesity; Oleic Acid; Phospholipids; Rats; Rats, Zucker; Triglycerides

2001
Effect of eicosapentaenoic acid ethyl ester v. oleic acid-rich safflower oil on insulin resistance in type 2 diabetic model rats with hypertriacylglycerolaemia.
    The British journal of nutrition, 2002, Volume: 87, Issue:2

    Topics: Abdomen; Adipose Tissue; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Dietary Supplements; Disease Models, Animal; Eating; Eicosapentaenoic Acid; Glucose Clamp Technique; Glucose Tolerance Test; Hypertriglyceridemia; Insulin Resistance; Lipid Metabolism; Liver; Male; Oleic Acid; Rats; Rats, Inbred OLETF; Safflower Oil; Triglycerides

2002
Metabolism of very low- and low-density lipoproteins isolated from normolipidaemic type 2 (non-insulin-dependent) diabetic patients by human monocyte-derived macrophages.
    Diabetologia, 1990, Volume: 33, Issue:5

    Topics: Apolipoproteins; Cholesterol; Cholesterol Esters; Diabetes Mellitus, Type 2; Female; Humans; In Vitro Techniques; Lipoproteins; Lipoproteins, LDL; Lipoproteins, VLDL; Macrophages; Male; Middle Aged; Monocytes; Oleic Acid; Oleic Acids; Reference Values; Triglycerides

1990
Effects of noninsulin-dependent diabetes mellitus on the uptake of very low density lipoproteins by thioglycolate-elicited mouse peritoneal macrophages.
    The Journal of clinical endocrinology and metabolism, 1985, Volume: 61, Issue:2

    Topics: Adult; Animals; Blood Glucose; Cell Membrane; Diabetes Mellitus, Type 2; Fasting; Female; Humans; In Vitro Techniques; Lipids; Lipoproteins, VLDL; Macrophages; Male; Mice; Middle Aged; Oleic Acid; Oleic Acids; Peritoneal Cavity; Thioglycolates; Triglycerides

1985