Compounds > oleanolic acid
Page last updated: 2024-08-21

oleanolic acid and Pain

oleanolic acid has been researched along with Pain in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (50.00)29.6817
2010's8 (40.00)24.3611
2020's2 (10.00)2.80

Authors

AuthorsStudies
Chang, SL; Chen, YI; Hsu, TH; Hung, PH; Lin, CM; Tsai, JC; Tzeng, CY1
Li, W; Liao, X; Liu, Y; Su, Y; Wang, Q; Xu, Y; Yu, Y; Zhang, J; Zhang, S; Zhao, M1
Arrau, S; Barriga, A; Cassels, BK; Delporte, C; Miranda, HF; Rodríguez-Díaz, M; Valenzuela-Barra, G1
Kang, YJ; Kim, CH; Kim, SJ; Kim, SS; Park, SH; Sim, YB; Suh, HW1
Deng, YT; Feng, B; Han, J; Li, S; Wang, DS; Wang, XS; Yang, Q; Zhao, MG1
Baggio, CH; Dos Santos, AC; Dos Santos, EP; Freitas, CS; Luiz, AP; Marcon, R; Marques, MC; Mayer, B; Pizzolatti, MG; Santos, AR; Soldi, C; Twardowschy, A1
Baggio, CH; Freitas, CS; Luiz, AP; Marcon, R; Nascimento, FP; Pizzolatti, MG; Santos, AR; Soldi, C; Werner, MF1
Arrau, S; Cartagena, C; Cassels, BK; Delporte, C; González, P; Miranda, HF; Rodríguez-Díaz, M; Silva, X1
Ching, H; Lin, LW; Lin, WH; Lin, YT; Wen, CL; Wu, CR1
Baggio, CH; da Silva, CF; das Neves, TL; Horst, H; Kanazawa, LK; Pizzolatti, MG; Rodrigues, MR; Santos, AR; Werner, MF1
Chang, YS; Ho, YL; Lai, SC; Liao, CR; Peng, WH1
Bednarczyk-Cwynar, B; Kaminska, E; Lewandowski, G; Marciniak, J; Mikolajczak, PL; Szulc, M; Wachowiak, N; Zaprutko, L1
Calixto, JB; Cani, GS; Ferreira, J; Lima, FV; Malheiros, A; Meyre-Silva, C; Muller, LA; Otuki, MF; Santos, AR; Yunes, RA1
Almeida, FR; Campos, AR; Cavalcante, IJ; Chaves, MH; Costa, CL; Lima, AF; Lima, RC; Oliveira, FA; Rao, VS; Santos, FA; Silva, RM1
David, JM; David, JP; Lima-Júnior, RC; Maia, JL; Rao, VS; Santos, FA1
Campos, AR; David, JM; David, JP; Lima-Júnior, RC; Maia, JL; Melo, CM; Rao, VS; Santos, FA1
Bland, JS; Carroll, B; Darland, G; Hall, A; Katke, J; Lamb, J; Lerman, RH; Minich, DM; Tripp, M1
Luiz, AP; Marcon, R; Meotti, FC; Mioto, LA; Pizzolatti, MG; Santos, AR; Soldi, C1
Brito, GA; Chaves, MH; Cunha, GM; Lima-Júnior, RC; Rao, VS; Santos, FA; Sousa, DI1
Aragão, GF; Cunha Pinheiro, MC; de Barros Viana, GS; Gomes Lemos, TL; Nogueira Bandeira, P1

Trials

1 trial(s) available for oleanolic acid and Pain

ArticleYear
Clinical safety and efficacy of NG440: a novel combination of rho iso-alpha acids from hops, rosemary, and oleanolic acid for inflammatory conditions.
    Canadian journal of physiology and pharmacology, 2007, Volume: 85, Issue:9

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Cell Count; Blood Coagulation; Blood Pressure; Cells, Cultured; Cross-Over Studies; Cyclopentanes; Dinoprostone; Double-Blind Method; Drug Combinations; Feces; Female; Humans; Humulus; Kidney Function Tests; Leukocyte L1 Antigen Complex; Liver Function Tests; Male; Mice; Naproxen; Oleanolic Acid; Pain; Plant Extracts; Rheumatic Diseases; Rosmarinus

2007

Other Studies

19 other study(ies) available for oleanolic acid and Pain

ArticleYear
Acetylsalicylic acid-like analgesic effects of Trametes versicolor in Wistar rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 129

    Topics: Analgesics; Animals; Aspirin; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Down-Regulation; Male; Oleanolic Acid; Pain; Pain Threshold; Polyporaceae; Rats, Wistar

2020
Active components of Bupleurum chinense and Angelica biserrata showed analgesic effects in formalin induced pain by acting on Nav1.7.
    Journal of ethnopharmacology, 2021, Apr-06, Volume: 269

    Topics: Analgesics; Angelica; Animals; Bupleurum; CHO Cells; Cricetulus; Disease Models, Animal; Drugs, Chinese Herbal; Female; Formaldehyde; Furocoumarins; Hot Temperature; Male; Medicine, Chinese Traditional; Mice; NAV1.7 Voltage-Gated Sodium Channel; Oleanolic Acid; Pain; Plant Roots; Saponins; Sodium

2021
Antihyperalgesic Activity of Quillaic Acid Obtained from Quillaja Saponaria Mol.
    Current topics in medicinal chemistry, 2019, Volume: 19, Issue:11

    Topics: Abdominal Muscles; Animals; Hypoglycemic Agents; Male; Mice; Mice, Inbred Strains; Molecular Conformation; Oleanolic Acid; Pain; Quillaja

2019
Mechanisms involved in the antinociceptive effects of orally administered oleanolic acid in the mouse.
    Archives of pharmacal research, 2013, Volume: 36, Issue:7

    Topics: Administration, Oral; Analgesics; Animals; Male; Mice; Mice, Inbred ICR; Oleanolic Acid; Pain; Pain Measurement

2013
Echinocystic acid reduces reserpine-induced pain/depression dyad in mice.
    Metabolic brain disease, 2016, Volume: 31, Issue:2

    Topics: Analgesics; Animals; Behavior, Animal; Brain; Depression; Depressive Disorder; Disease Models, Animal; Dopamine; Male; Mice, Inbred C57BL; Oleanolic Acid; Pain; Pain Threshold; Receptors, N-Methyl-D-Aspartate; Reserpine; Serotonin

2016
Antinociceptive properties of the hydroalcoholic extract, fractions and compounds obtained from the aerial parts of Baccharis illinita DC in mice.
    Basic & clinical pharmacology & toxicology, 2009, Volume: 104, Issue:4

    Topics: Analgesics; Animals; Baccharis; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Mice; Oleanolic Acid; Pain; Pain Measurement; Plant Components, Aerial; Plant Extracts; Receptors, Glutamate; Solvents; Stigmasterol; Triterpenes

2009
Evidence of TRPV1 receptor and PKC signaling pathway in the antinociceptive effect of amyrin octanoate.
    Brain research, 2009, Oct-27, Volume: 1295

    Topics: Acetic Acid; Analgesics; Analysis of Variance; Animals; Capsaicin; Dose-Response Relationship, Drug; Female; Hot Temperature; Hyperalgesia; Male; Mice; Motor Activity; Neurons; Oleanolic Acid; Opioid Peptides; Pain; Pain Measurement; Physical Stimulation; Protein Kinase C; Psychomotor Performance; Rats; Rats, Wistar; Serotonin; Signal Transduction; TRPV Cation Channels

2009
Antinociceptive activity of Quillaja saponaria Mol. saponin extract, quillaic acid and derivatives in mice.
    Journal of ethnopharmacology, 2011, Jan-07, Volume: 133, Issue:1

    Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Male; Mice; Oleanolic Acid; Pain; Phytotherapy; Plant Bark; Plant Extracts; Quillaja; Saponins; Triterpenes

2011
Analgesic and anti-inflammatory property of the methanol extract from Ligustrum morrisonense leaves in rodents.
    The American journal of Chinese medicine, 2011, Volume: 39, Issue:2

    Topics: Abdomen; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Capillary Permeability; Carrageenan; Cyclooxygenase 2 Inhibitors; Edema; Extravasation of Diagnostic and Therapeutic Materials; Formaldehyde; Inflammation; Inflammation Mediators; Ligustrum; Male; Mice; Mice, Inbred ICR; Oleanolic Acid; Pain; Pentacyclic Triterpenes; Phytotherapy; Plant Components, Aerial; Plant Extracts; Plant Leaves; Rats; Rats, Sprague-Dawley; Triterpenes

2011
Antinociceptive and anti-inflammatory potential of extract and isolated compounds from the leaves of Salvia officinalis in mice.
    Journal of ethnopharmacology, 2012, Jan-31, Volume: 139, Issue:2

    Topics: Abietanes; Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Inflammation; Lethal Dose 50; Mice; Motor Activity; Narcotic Antagonists; Oleanolic Acid; Pain; Pain Measurement; Plant Extracts; Plant Leaves; Plants, Medicinal; Salvia officinalis; Time Factors; Triterpenes; Ursolic Acid

2012
Analgesic and anti-inflammatory activities of the methanol extract of Elaeagnus oldhamii Maxim. in mice.
    The American journal of Chinese medicine, 2012, Volume: 40, Issue:3

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Behavior, Animal; Carrageenan; Cyclooxygenase 2 Inhibitors; Edema; Elaeagnaceae; Flavonoids; Flavonols; Formaldehyde; Inflammation; Inflammation Mediators; Liver; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Nitric Oxide; Oleanolic Acid; Pain; Phytotherapy; Plant Extracts; Polyphenols; Triterpenes; Ursolic Acid

2012
The analgesic and anti-inflammatory effect of new oleanolic acid acyloxyimino derivative.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2012, Oct-09, Volume: 47, Issue:3

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Drug Eruptions; Drug Synergism; Edema; Male; Mice; Morphine; Motor Activity; Oleanolic Acid; Pain; Rats; Rats, Wistar; Toxicity Tests, Acute

2012
Antinociceptive properties of mixture of alpha-amyrin and beta-amyrin triterpenes: evidence for participation of protein kinase C and protein kinase A pathways.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 313, Issue:1

    Topics: Acetic Acid; Analgesics; Animals; Bradykinin; Cyclic AMP-Dependent Protein Kinases; Diterpenes; Dose-Response Relationship, Drug; Drug Combinations; Formaldehyde; Glutamic Acid; Heart; Male; Mice; Oleanolic Acid; Pain; Pain Measurement; Peripheral Nervous System; Physical Stimulation; Protein Kinase C; Psychomotor Performance; Rats; Rats, Wistar; Reaction Time; Spinal Cord; Stimulation, Chemical; Triterpenes

2005
Attenuation of capsaicin-induced acute and visceral nociceptive pain by alpha- and beta-amyrin, a triterpene mixture isolated from Protium heptaphyllum resin in mice.
    Life sciences, 2005, Oct-21, Volume: 77, Issue:23

    Topics: Administration, Oral; Analgesics; Animals; Behavior, Animal; Burseraceae; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Hypothermia; Mice; Motor Activity; Oleanolic Acid; Pain; Postural Balance; Resins, Plant; Sleep

2005
Oleanolic Acid, a pentacyclic triterpene attenuates the mustard oil-induced colonic nociception in mice.
    Biological & pharmaceutical bulletin, 2006, Volume: 29, Issue:1

    Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Colonic Diseases; Dose-Response Relationship, Drug; Male; Mice; Motor Activity; Mustard Plant; Oleanolic Acid; Pain; Plant Oils; Ruthenium Red; TRPV Cation Channels; Yohimbine

2006
Oleanolic acid, a pentacyclic triterpene attenuates capsaicin-induced nociception in mice: possible mechanisms.
    Pharmacological research, 2006, Volume: 54, Issue:4

    Topics: Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Capsaicin; Coloring Agents; Enzyme Inhibitors; Glyburide; Hypoglycemic Agents; KATP Channels; Lamiaceae; Male; Mice; Morphine; Motor Activity; Naloxone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Oleanolic Acid; Pain; Pain Measurement; Postural Balance; Potassium Channels, Inwardly Rectifying; Ruthenium Red; Yohimbine

2006
Synthetic derivatives of the alpha- and beta-amyrin triterpenes and their antinociceptive properties.
    Bioorganic & medicinal chemistry, 2008, Mar-15, Volume: 16, Issue:6

    Topics: Analgesics; Animals; Disease Models, Animal; Mice; Molecular Structure; Oleanolic Acid; Pain; Structure-Activity Relationship; Triterpenes

2008
Modulation of acute visceral nociception and bladder inflammation by plant triterpene, alpha, beta-amyrin in a mouse model of cystitis: role of tachykinin NK(1)-receptors, and K(+)(ATP) channels.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2007, Volume: 56, Issue:12

    Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Cyclophosphamide; Cystitis; Edema; Glyburide; KATP Channels; Male; Mice; Oleanolic Acid; Pain; Receptors, Neurokinin-1; TRPV Cation Channels; Urinary Bladder

2007
Analgesic and anti-inflammatory activities of the isomeric mixture of alpha- and beta-amyrin from Protium heptaphyllum (Aubl.) march.
    Journal of herbal pharmacotherapy, 2007, Volume: 7, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Dextrans; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Mice; Oleanolic Acid; Pain; Pain Measurement; Phytotherapy

2007