Page last updated: 2024-08-21

oleanolic acid and Ovarian Neoplasms

oleanolic acid has been researched along with Ovarian Neoplasms in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (33.33)29.6817
2010's11 (52.38)24.3611
2020's3 (14.29)2.80

Authors

AuthorsStudies
Johnson, RK; Kingston, DG; Prakash Chaturvedula, VS; Schilling, JK1
Bian, M; Fan, R; Liu, W; Liu, Y; Liu, Z; Sun, Y; Xu, Z1
Chen, L; Chen, YC; Li, B; Rankin, GO; Ren, N; Rojanasakul, Y; Tu, Y; Wang, Y; Wu, Y1
Bremner, DH; Chen, X; Li, S; Niu, S; Zhang, H; Zhang, X; Zhang, Y; Zhu, LM1
Chou, YT; Hsieh, SL; Lee, OK; Sung, PL; Wang, PH; Wen, KC; Wu, CW1
Chang, CM; Chen, YJ; Horng, HC; Lee, WL; Sung, PL; Wang, PH; Wen, KC1
Bucur, H; Chen, YC; Chen, ZD; Compton, C; Jia, LY; Li, B; Rankin, GO; Sawant, DA; Tu, YY; Xia, HL1
Gao, FH; Lei, H; Ma, CM; Qin, DJ; Tang, CX; Wang, YY; Wei, W; Wu, YL; Xu, HZ; Yang, L1
Chen, Y; Feng, X; Guan, F; Shan, Y; Wang, M; Wang, Q; Zhao, X1
Cho, YJ; Choi, JH; Jang, DS; Lee, JS; Lee, KT; Woo, JH1
Cai, H; Gao, F; Jin, J; Lei, H; Luo, H; Ma, C; Qin, D; Tang, C; Wang, T; Wang, W; Wang, Y; Wu, Y; Wu, YL; Xiao, W; Xu, H; Zhang, J1
Chen, P; Chen, X; Lin, LG; Lu, JJ; Meng, FC; Qiang, WA; Tang, ZH; Wang, YT; Wu, QS; Zhang, QW1
Ames, RY; Duan, Z; Hornicek, FJ; Mankin, H; Ryan, M; Seiden, MV1
Benedetti-Panici, P; Biffoni, M; Cognetti, F; Ferretti, G; Greggi, S; Mariani, G; Pasquini, L; Petronelli, A; Petrucci, E; Russo, MA; Saulle, E; Scambia, G; Sporn, M; Testa, U1
Brodie, PJ; Callmander, M; Cao, S; Kingston, DG; Rakotobe, E; Randrianaivo, R; Rasamison, VE1
Arbab, AS; Deeb, D; Dulchavsky, SA; Gao, X; Gautam, SC; Guo, AM; Liu, Y1
Arbab, AS; Deeb, D; Gao, X; Gautam, SC; Liu, A; Liu, P; Liu, Y1
Andriantsiferana, R; Chaturvedula, VS; Kingston, DG; Miller, JS; Rasamison, VE; Schilling, JK1
Andreeff, M; Freedman, RS; Hu, W; Konopleva, M; Melichar, B; Melicharova, K1
Berger, JM; Bursuker, I; Hoch, J; Kingston, DG; Mamber, SW; Neddermann, KM; Seo, Y1
Abdel-Kader, M; Adams, H; Dalton, JM; Derveld, I; Hoch, J; Kingston, DG; Malone, S; Mamber, SW; Seo, Y; Werkhoven, MC; Wisse, JH1

Other Studies

21 other study(ies) available for oleanolic acid and Ovarian Neoplasms

ArticleYear
New cytotoxic lupane triterpenoids from the twigs of Coussarea paniculata.
    Journal of natural products, 2003, Volume: 66, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Female; Guyana; Humans; Inhibitory Concentration 50; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Ovarian Neoplasms; Plant Stems; Plants, Medicinal; Rubiaceae; Stereoisomerism; Triterpenes; Tumor Cells, Cultured

2003
A Gold(I) Complex Containing an Oleanolic Acid Derivative as a Potential Anti-Ovarian-Cancer Agent by Inhibiting TrxR and Activating ROS-Mediated ERS.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2020, Jun-02, Volume: 26, Issue:31

    Topics: Antineoplastic Agents; Antioxidants; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Coordination Complexes; Endoplasmic Reticulum Stress; Female; Gold; Humans; Oleanolic Acid; Ovarian Neoplasms; Oxidation-Reduction; Reactive Oxygen Species; Thioredoxin-Disulfide Reductase

2020
Standardized Saponin Extract from Baiye No.1 Tea (
    Molecules (Basel, Switzerland), 2020, Jul-31, Volume: 25, Issue:15

    Topics: Apoptosis; Camellia sinensis; Cell Line, Tumor; Cell Survival; Cyclin A2; Cyclin-Dependent Kinase Inhibitor p27; Female; Flowers; Gene Expression Regulation; Humans; Oleanolic Acid; Ovarian Neoplasms; Plant Extracts; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-mdm2; S Phase Cell Cycle Checkpoints; Saponins; Signal Transduction; Tumor Suppressor Protein p53

2020
Co-delivery of doxorubicin and oleanolic acid by triple-sensitive nanocomposite based on chitosan for effective promoting tumor apoptosis.
    Carbohydrate polymers, 2020, Nov-01, Volume: 247

    Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Cell Proliferation; Chitosan; Doxorubicin; Drug Carriers; Drug Delivery Systems; Female; Humans; Hydrogen-Ion Concentration; Mice; Nanocomposites; Oleanolic Acid; Ovarian Neoplasms; Tissue Distribution; Tumor Cells, Cultured; Tumor Microenvironment; Xenograft Model Antitumor Assays

2020
α2,3-sialyltransferase type I regulates migration and peritoneal dissemination of ovarian cancer cells.
    Oncotarget, 2017, Apr-25, Volume: 8, Issue:17

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; beta-Galactoside alpha-2,3-Sialyltransferase; Biomarkers, Tumor; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cell Movement; Drug Synergism; ErbB Receptors; Female; Humans; Immunohistochemistry; Immunoprecipitation; Kaplan-Meier Estimate; Mice; Mice, Inbred C57BL; Microarray Analysis; Neoplasm Invasiveness; Neoplasm Staging; Neoplasms, Glandular and Epithelial; Oleanolic Acid; Ovarian Neoplasms; Ovary; Peritoneal Neoplasms; Peritoneum; Prognosis; Protein Kinase Inhibitors; Saponins; Sialyltransferases; Signal Transduction; Survival Rate

2017
The role of α2,3-linked sialylation on clear cell type epithelial ovarian cancer.
    Taiwanese journal of obstetrics & gynecology, 2018, Volume: 57, Issue:2

    Topics: Adenocarcinoma, Clear Cell; Animals; beta-Galactoside alpha-2,3-Sialyltransferase; Cadherins; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cystadenocarcinoma, Serous; Female; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Mice; Neoplasms, Glandular and Epithelial; Oleanolic Acid; Ovarian Neoplasms; Saponins; Sialyltransferases

2018
Anti-Proliferation Effect of Theasaponin E₁ on the ALDH-Positive Ovarian Cancer Stem-Like Cells.
    Molecules (Basel, Switzerland), 2018, Jun-17, Volume: 23, Issue:6

    Topics: Aldehyde Dehydrogenase; Biomarkers; Cell Proliferation; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Molecular Structure; Neoplastic Stem Cells; Oleanolic Acid; Ovarian Neoplasms; Saponins; Tea

2018
Hsp90 Is a Novel Target Molecule of CDDO-Me in Inhibiting Proliferation of Ovarian Cancer Cells.
    PloS one, 2015, Volume: 10, Issue:7

    Topics: Antineoplastic Agents; Cell Division; Cell Line, Tumor; Dithiothreitol; Drug Screening Assays, Antitumor; Female; Gene Expression Regulation, Neoplastic; Genes, erbB-2; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; MAP Kinase Signaling System; Molecular Structure; Molecular Targeted Therapy; Neoplasm Proteins; Oleanolic Acid; Ovarian Neoplasms; Proto-Oncogene Proteins c-akt; Receptor, ErbB-2; RNA Interference; RNA, Small Interfering; Structure-Activity Relationship; Transfection; Up-Regulation

2015
Macranthoside B Induces Apoptosis and Autophagy Via Reactive Oxygen Species Accumulation in Human Ovarian Cancer A2780 Cells.
    Nutrition and cancer, 2016, Volume: 68, Issue:2

    Topics: AMP-Activated Protein Kinases; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Cell Line, Tumor; Dose-Response Relationship, Drug; Female; Humans; Oleanolic Acid; Ovarian Neoplasms; Reactive Oxygen Species; Saponins; TOR Serine-Threonine Kinases

2016
Eclalbasaponin II induces autophagic and apoptotic cell death in human ovarian cancer cells.
    Journal of pharmacological sciences, 2016, Volume: 132, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Autophagy; Cell Line, Tumor; Female; Humans; JNK Mitogen-Activated Protein Kinases; Oleanolic Acid; Ovarian Neoplasms; p38 Mitogen-Activated Protein Kinases; Saponins; TOR Serine-Threonine Kinases

2016
CDDO-Me reveals USP7 as a novel target in ovarian cancer cells.
    Oncotarget, 2016, Nov-22, Volume: 7, Issue:47

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Molecular Docking Simulation; Oleanolic Acid; Ovarian Neoplasms; Ubiquitin-Specific Peptidase 7; Up-Regulation; Xenograft Model Antitumor Assays

2016
Chikusetsusaponin IVa methyl ester induces G1 cell cycle arrest, triggers apoptosis and inhibits migration and invasion in ovarian cancer cells.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2016, Dec-01, Volume: 23, Issue:13

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Cyclin D1; Cyclin-Dependent Kinase 2; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Female; G1 Phase Cell Cycle Checkpoints; Humans; Membrane Potential, Mitochondrial; Molecular Structure; Oleanolic Acid; Ovarian Neoplasms; Saponins

2016
CDDO-Me, a synthetic triterpenoid, inhibits expression of IL-6 and Stat3 phosphorylation in multi-drug resistant ovarian cancer cells.
    Cancer chemotherapy and pharmacology, 2009, Volume: 63, Issue:4

    Topics: Apoptosis; Blotting, Western; Cell Proliferation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Interleukin-6; Oleanolic Acid; Ovarian Neoplasms; Phosphorylation; Protein Transport; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; STAT3 Transcription Factor; Tumor Cells, Cultured

2009
High sensitivity of ovarian cancer cells to the synthetic triterpenoid CDDO-Imidazolide.
    Cancer letters, 2009, Sep-18, Volume: 282, Issue:2

    Topics: Antibiotics, Antineoplastic; Apoptosis; bcl-2-Associated X Protein; Caspase 8; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Enzyme Activation; Female; Glutathione; Humans; Imidazoles; Mitochondria; Oleanolic Acid; Ovarian Neoplasms; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; STAT3 Transcription Factor; TNF-Related Apoptosis-Inducing Ligand

2009
Saponins and a lignan derivative of Terminalia tropophylla from the Madagascar Dry Forest.
    Phytochemistry, 2010, Volume: 71, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Ecosystem; Female; Humans; Inhibitory Concentration 50; Lignans; Madagascar; Molecular Structure; Oleanolic Acid; Ovarian Neoplasms; Phytotherapy; Plant Extracts; Plant Roots; Saponins; Terminalia; Triterpenes

2010
Synthetic oleanane triterpenoid, CDDO-Me, induces apoptosis in ovarian cancer cells by inhibiting prosurvival AKT/NF-κB/mTOR signaling.
    Anticancer research, 2011, Volume: 31, Issue:11

    Topics: Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Survival; Female; Gene Expression Regulation, Neoplastic; Humans; Mitochondria; NF-kappa B; Oleanolic Acid; Ovarian Neoplasms; Proto-Oncogene Proteins c-akt; TOR Serine-Threonine Kinases

2011
ROS mediate proapoptotic and antisurvival activity of oleanane triterpenoid CDDO-Me in ovarian cancer cells.
    Anticancer research, 2013, Volume: 33, Issue:1

    Topics: Acetylcysteine; Apoptosis; Cell Line, Tumor; Cell Proliferation; Female; Humans; Hydrogen Peroxide; Oleanolic Acid; Ovarian Neoplasms; Reactive Oxygen Species; Signal Transduction

2013
Two new triterpene esters from the twigs of Brachylaena ramiflora from the Madagascar rainforest.
    Journal of natural products, 2002, Volume: 65, Issue:8

    Topics: Antineoplastic Agents, Phytogenic; Asteraceae; Drug Screening Assays, Antitumor; Esters; Female; Humans; Inhibitory Concentration 50; Madagascar; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oleanolic Acid; Ovarian Neoplasms; Palmitates; Pentacyclic Triterpenes; Plant Shoots; Plants, Medicinal; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Triterpenes; Tumor Cells, Cultured

2002
Growth-inhibitory effect of a novel synthetic triterpenoid, 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, on ovarian carcinoma cell lines not dependent on peroxisome proliferator-activated receptor-gamma expression.
    Gynecologic oncology, 2004, Volume: 93, Issue:1

    Topics: Antineoplastic Agents; Cell Division; Cell Line, Tumor; Female; Growth Inhibitors; Humans; Oleanolic Acid; Ovarian Neoplasms; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factors

2004
A new triterpene saponin from Pittosporum viridiflorum from the Madagascar rainforest.
    Journal of natural products, 2002, Volume: 65, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Chromatography, Thin Layer; Drug Screening Assays, Antitumor; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydrolysis; Madagascar; Nuclear Magnetic Resonance, Biomolecular; Oleanolic Acid; Ovarian Neoplasms; Plants, Medicinal; Saccharomyces cerevisiae; Saponins; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Structure-Activity Relationship; Triterpenes; Tumor Cells, Cultured

2002
Bioactive saponins from Acacia tenuifolia from the suriname rainforest.
    Journal of natural products, 2002, Volume: 65, Issue:2

    Topics: Acacia; Animals; Antifungal Agents; Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Female; Gas Chromatography-Mass Spectrometry; Humans; Inhibitory Concentration 50; Lung Neoplasms; Mice; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oleanolic Acid; Ovarian Neoplasms; Plants, Medicinal; Saponins; Stereoisomerism; Suriname; Triterpenes; Tumor Cells, Cultured; Yeasts

2002