Page last updated: 2024-08-21

oleanolic acid and Osteosarcoma

oleanolic acid has been researched along with Osteosarcoma in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's6 (85.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dong, Y; Shu, B; Tian, Y; Wang, G; Wang, J; Wang, Y; Xu, Y1
Gao, F; Jiang, T; Song, H; Zhou, J; Zuo, Q1
Cai, Z; Hu, S; Hua, Y; Li, J; Li, Q; Sun, M; Zhang, Z1
Choy, E; Duan, Z; Hornicek, FJ; Mankin, H; Ryu, K; Susa, M; Yang, C1
Choy, E; Duan, Z; Hornicek, FJ; Mankin, HJ; Ryu, K; Susa, M; Yang, C1
Bai, X; Huang, M; Jia, C; Jin, D; Lu, M; Mai, Q; Wang, L; Wang, X; Xu, S; Zhang, Z; Zhao, L; Zhou, R1
Datta, R; Ito, Y; Kharbanda, S; Kufe, D; Pandey, P; Sporn, MB1

Other Studies

7 other study(ies) available for oleanolic acid and Osteosarcoma

ArticleYear
Oleanolic acid induces osteosarcoma cell apoptosis by inhibition of Notch signaling.
    Molecular carcinogenesis, 2018, Volume: 57, Issue:7

    Topics: Apoptosis; Cell Line, Tumor; Humans; Membrane Potential, Mitochondrial; Mitochondria; Oleanolic Acid; Osteosarcoma; Receptors, Notch; Signal Transduction

2018
A newly synthesized oleanolic acid derivative inhibits the growth of osteosarcoma cells in vitro and in vivo by decreasing c-MYC-dependent glycolysis.
    Journal of cellular biochemistry, 2019, Volume: 120, Issue:6

    Topics: Adenosine Triphosphate; Animals; Apoptosis; Cell Proliferation; Cell Survival; Gene Expression Regulation, Neoplastic; Glucose; Glycolysis; Hep G2 Cells; Heterografts; Humans; Mice; Oleanolic Acid; Osteosarcoma; PPAR gamma; Proto-Oncogene Proteins c-myc

2019
Oleanolic acid derivative Dex-OA has potent anti-tumor and anti-metastatic activity on osteosarcoma cells in vitro and in vivo.
    Investigational new drugs, 2011, Volume: 29, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Flow Cytometry; Humans; Inhibitory Concentration 50; Lung Neoplasms; Mice; Oleanolic Acid; Osteosarcoma; S Phase

2011
Activation of signal transducer and activator of transcription 3 (Stat3) pathway in osteosarcoma cells and overexpression of phosphorylated-Stat3 correlates with poor prognosis.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2010, Volume: 28, Issue:7

    Topics: Adolescent; Apoptosis; Biomarkers, Tumor; Bone Neoplasms; Cell Division; Cell Line, Tumor; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Immunohistochemistry; Male; Middle Aged; Oleanolic Acid; Osteosarcoma; Phosphorylation; Prognosis; Signal Transduction; STAT3 Transcription Factor; Young Adult

2010
Oleanane triterpenoid CDDO-Me induces apoptosis in multidrug resistant osteosarcoma cells through inhibition of Stat3 pathway.
    BMC cancer, 2010, May-10, Volume: 10

    Topics: Active Transport, Cell Nucleus; Antineoplastic Agents; Apoptosis; bcl-X Protein; Bone Neoplasms; Caspase 3; Caspase 7; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Humans; Inhibitor of Apoptosis Proteins; Microtubule-Associated Proteins; Myeloid Cell Leukemia Sequence 1 Protein; Oleanolic Acid; Osteosarcoma; Phosphorylation; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; STAT3 Transcription Factor; Survivin; Time Factors

2010
Inhibition of mTOR signaling by oleanolic acid contributes to its anti-tumor activity in osteosarcoma cells.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2011, Volume: 29, Issue:6

    Topics: Apoptosis; Bone Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Humans; Mechanistic Target of Rapamycin Complex 1; Multiprotein Complexes; Oleanolic Acid; Osteosarcoma; Proteins; TOR Serine-Threonine Kinases; Transcription Factors

2011
The novel triterpenoid CDDO induces apoptosis and differentiation of human osteosarcoma cells by a caspase-8 dependent mechanism.
    Molecular pharmacology, 2001, Volume: 59, Issue:5

    Topics: Apoptosis; Caspase 8; Caspase 9; Caspases; Cell Differentiation; Cytochrome c Group; Enzyme Activation; Humans; Mitochondria; Oleanolic Acid; Osteosarcoma; Tumor Cells, Cultured

2001