oleanolic acid has been researched along with Malignant Melanoma in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (7.69) | 18.2507 |
| 2000's | 3 (11.54) | 29.6817 |
| 2010's | 17 (65.38) | 24.3611 |
| 2020's | 4 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Assefa, H; Nimrod, A; Sindelar, R; Walker, L | 2 |
| Garcia-Granados, A; Martin-Fonseca, S; Martinez, A; Parra, A; Rivas, F | 1 |
| Hassan, M; Hwan Lee, K; Ja Kim, S; Raza, H; Seok Eom, Y; Vanjare, BD | 1 |
| Bhandari, R; Khatwani, N; Liby, KT; Park, C; Pioli, PA; Spezza, PA; Torres, GM; Yang, H | 1 |
| Eom, YS; Hassan, M; Hosseini Nasab, N; Kim, SJ; Kloczkowski, A; Raza, H | 1 |
| Al-Harrasi, A; Csuk, R; Deigner, HP; Heise, N; Hoenke, S; Simon, V | 1 |
| Chung, G; Golokhvast, KS; Izotov, BN; Kim, HS; Le, B; Sifaki, M; Spandidos, DA; Tsatsakis, AM; Tsukamoto, C; Tzanakakis, G; Yang, SH | 1 |
| Bojin, F; Caunii, A; Cristea, M; Drăghia, L; Ivan, A; Oprean, C; Paunescu, V; Soica, C; Tatu, C | 1 |
| Avram, S; Caunii, A; Cristea, M; Danciu, C; Dehelean, C; Ivan, A; Marti, D; Oprean, C; Paunescu, V; Soica, C; Spandidos, DA; Susan, R; Tatu, C; Tsatsakis, A; Tzanakakis, G | 1 |
| Li, TH; Yan, HX | 1 |
| Alvarado, HL; Calpena, AC; Clares, B; Garduño-Ramírez, ML; Melguizo, C; Ortiz, R; Prados, JC | 1 |
| Lee, HB; Sharma, M; Tailor, NK | 1 |
| Chatterjee, N; Das, S; Kumar, D; Mallick, S; Pal, BC; Saha, KD | 1 |
| Bishayee, A; Biswas, J; Dutta, K; Ganguly, KK; Sinha, D | 1 |
| Bishayee, K; Ghosh, S; Khuda-Bukhsh, AR | 1 |
| Borcan, F; Coricovac, D; Crăiniceanu, Z; Danciu, C; Dehelean, CA; Munteanu, M; Oprean, C; Soica, C; Trandafirescu, C | 1 |
| Huang, L; Huo, M; Wang, Y; Xu, Z; Zhao, Y | 1 |
| Hu, SC; Lee, CW; Lee, IT; Lin, CC; Yen, FL; Yen, MH | 1 |
| Hayakawa, Y; Ma, H; Saiki, I; Yokoyama, S | 1 |
| Galanty, A; Michalik, M; Podolak, I; Sedek, L | 1 |
| Fernandes, J; Gattass, CR; Lúcio, KA; Monção-Ribeiro, LC; Rocha, Gda G; Takiya, CM | 1 |
| Andreeff, M; Dezube, BJ; Eder, JP; Ferguson, DA; He, X; Hong, DS; Konoplev, S; Konopleva, M; Kufe, D; Kurzrock, R; Lawrence, D; Lazarus, H; Meyer, CJ; Mier, J; Naing, A; Shapiro, GI; Supko, JG; Wheler, J | 1 |
| Deng, W; Ekmekcioglu, S; Grimm, EA; Qin, Y | 1 |
| Chang, HC; Chang, JJ; Chen, HT; Chen, YP; Cheng, CM; Kashiwada, Y; Lee, KH; Zhang, DC | 1 |
| Kim, DS; Kim, JY; Koo, HM | 1 |
1 trial(s) available for oleanolic acid and Malignant Melanoma
| Article | Year |
|---|---|
A phase I first-in-human trial of bardoxolone methyl in patients with advanced solid tumors and lymphomas.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Colorectal Neoplasms; Cyclin D1; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Janus Kinases; Kidney Neoplasms; Lymphoma; Male; Maximum Tolerated Dose; Melanoma; Middle Aged; NAD(P)H Dehydrogenase (Quinone); Neoplasms; NF-E2-Related Factor 2; NF-kappa B; Oleanolic Acid; RNA, Messenger; STAT Transcription Factors; Thyroid Neoplasms; Young Adult | 2012 |
25 other study(ies) available for oleanolic acid and Malignant Melanoma
| Article | Year |
|---|---|
Synthesis and evaluation of potential complement inhibitory semisynthetic analogs of oleanolic acid.
Topics: Antineoplastic Agents; Apoptosis; Complement Inactivator Proteins; DNA Fragmentation; Drug Evaluation, Preclinical; Humans; Melanoma; Oleanolic Acid; Structure-Activity Relationship; Tumor Cells, Cultured | 1999 |
Enantioselective synthesis and complement inhibitory assay of A/B-ring partial analogues of oleanolic acid.
Topics: Antineoplastic Agents; Complement Inactivator Proteins; Drug Screening Assays, Antitumor; Humans; Melanoma; Oleanolic Acid; Stereoisomerism; Tumor Cells, Cultured | 2001 |
Maslinic acid derivatives induce significant apoptosis in b16f10 murine melanoma cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Melanoma; Mice; Olea; Triterpenes | 2011 |
Elastase inhibitory activity of quinoline Analogues: Synthesis, kinetic mechanism, cytotoxicity, chemoinformatics and molecular docking studies.
Topics: alpha-Glucosidases; Cheminformatics; Glycoside Hydrolase Inhibitors; Humans; Melanoma; Molecular Docking Simulation; Oleanolic Acid; Pancreatic Elastase; Quinolines; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship | 2022 |
T Cells and CDDO-Me Attenuate Immunosuppressive Activation of Human Melanoma-Conditioned Macrophages.
Topics: Humans; Immunosuppressive Agents; Macrophages; Melanoma; Oleanolic Acid; T-Lymphocytes; Tumor Microenvironment | 2022 |
Design and synthesis of thiadiazole-oxadiazole-acetamide derivatives: Elastase inhibition, cytotoxicity, kinetic mechanism, and computational studies.
Topics: Acetamides; Amides; Humans; Kinetics; Melanoma; Molecular Docking Simulation; Molecular Structure; Oleanolic Acid; Oxadiazoles; Pancreatic Elastase; Structure-Activity Relationship; Thiadiazoles | 2023 |
Type and position of linkage govern the cytotoxicity of oleanolic acid rhodamine B hybrids.
Topics: Antineoplastic Agents; Cell Proliferation; Humans; Melanoma; Oleanolic Acid; Rhodamines; Tumor Cells, Cultured | 2021 |
Soyasaponin Ag inhibits α‑MSH‑induced melanogenesis in B16F10 melanoma cells via the downregulation of TRP‑2.
Topics: alpha-MSH; Animals; Cell Line, Tumor; Down-Regulation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Intramolecular Oxidoreductases; Melanins; Melanoma; Mice; Neoplasm Proteins; Oleanolic Acid; Saponins | 2017 |
Selective in vitro anti-melanoma activity of ursolic and oleanolic acids.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Humans; Melanoma; Mesenchymal Stem Cells; Oleanolic Acid; Triterpenes; Ursolic Acid | 2018 |
Effects of ursolic and oleanolic on SK‑MEL‑2 melanoma cells: In vitro and in vivo assays.
Topics: Angiogenesis Inhibitors; Animals; Cell Adhesion; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chick Embryo; Chorioallantoic Membrane; Humans; Melanoma; Neovascularization, Physiologic; Oleanolic Acid; Skin Neoplasms; Triterpenes; Ursolic Acid | 2017 |
Antitumor‑ and apoptosis‑inducing effects of pomolic acid against SK‑MEL‑2 human malignant melanoma cells are mediated via inhibition of cell migration and sub‑G1 cell cycle arrest.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; G1 Phase Cell Cycle Checkpoints; Humans; Melanoma; Oleanolic Acid | 2018 |
Nanoemulsion Strategy for Ursolic and Oleanic Acids Isolates from
Topics: Animals; Antioxidants; Apocynaceae; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Emulsions; Melanoma; Mice; Molecular Conformation; Nanoparticles; Oleanolic Acid; Structure-Activity Relationship; Triterpenes; Ursolic Acid | 2018 |
Effective melanoma inhibition by synthetic pentacyclic triterpenoid 2-(3-phenylprop-2-en-1-ylidene)-22β-hydroxy-3-oxoolean-12-en-28-oic acid: an in vitro and in vivo study.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Cycle; Cell Line, Tumor; Cells, Cultured; Chlorocebus aethiops; Disease Models, Animal; DNA Fragmentation; In Vitro Techniques; Male; Melanoma; Mice; Mice, Inbred C57BL; NF-kappa B; Oleanolic Acid; Pentacyclic Triterpenes; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-jun; Skin Neoplasms; Survival Rate; Transplantation, Homologous; Vero Cells | 2013 |
Effect of corchorusin-D, a saikosaponin like compound, on B16F10 melanoma cells (in vitro and in vivo).
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Caspase 9; Corchorus; Glycosides; Humans; Melanoma; Membrane Potential, Mitochondrial; Mice; Mitochondria; Molecular Structure; Oleanolic Acid; Saponins; Skin Neoplasms; Triterpenes | 2013 |
A novel synthetic oleanane triterpenoid suppresses adhesion, migration, and invasion of highly metastatic melanoma cells by modulating gelatinase signaling axis.
Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Movement; Gelatinases; Gene Expression Regulation, Neoplastic; Melanoma; Mice; Neoplasm Invasiveness; Oleanolic Acid; Signal Transduction | 2015 |
Oleanolic acid isolated from ethanolic extract of Phytolacca decandra induces apoptosis in A375 skin melanoma cells: drug-DNA interaction and signaling cascade.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; DNA, Neoplasm; ErbB Receptors; Humans; Melanoma; Microscopy, Fluorescence; Oleanolic Acid; Phytolacca; Phytotherapy; Plant Extracts; Signal Transduction; Skin Neoplasms | 2014 |
The synergistic biologic activity of oleanolic and ursolic acids in complex with hydroxypropyl-γ-cyclodextrin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Biological Availability; Cell Line, Tumor; Cell Survival; Drug Carriers; Drug Synergism; Female; gamma-Cyclodextrins; Humans; Melanoma; Mice; Oleanolic Acid; Skin Neoplasms; Solubility; Triterpenes; Ultraviolet Rays; Ursolic Acid | 2014 |
Nanoparticle delivery of CDDO-Me remodels the tumor microenvironment and enhances vaccine therapy for melanoma.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cancer Vaccines; Cell Line, Tumor; Drug Synergism; Female; Melanoma; Membrane Proteins; Mice; Mice, Inbred C57BL; Nanocapsules; Oleanolic Acid; Particle Size; Peptide Fragments; Treatment Outcome; Tumor Microenvironment | 2015 |
Anti-melanoma activity of Bupleurum chinense, Bupleurum kaoi and nanoparticle formulation of their major bioactive compound saikosaponin-d.
Topics: Apoptosis Regulatory Proteins; Bupleurum; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Drugs, Chinese Herbal; Humans; MAP Kinase Signaling System; Melanoma; Membrane Potential, Mitochondrial; Nanoparticles; Oleanolic Acid; Particle Size; Plant Roots; Saponins; Solubility | 2016 |
Chemosensitizing Effect of Saikosaponin B on B16F10 Melanoma Cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Death; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Etoposide; Melanoma; Mice; NF-kappa B; Oleanolic Acid; Saponins; Signal Transduction | 2017 |
The influence of LTS-4, a saponoside from Lysimachia thyrsiflora L., on human skin fibroblasts and human melanoma cells.
Topics: Animals; Cell Proliferation; Cell Shape; Cell Survival; Cells, Cultured; Cytoskeleton; Fibroblasts; Humans; Melanoma; Oleanolic Acid; Primulaceae; Saponins; Skin | 2008 |
Oleanolic acid initiates apoptosis in non-small cell lung cancer cell lines and reduces metastasis of a B16F10 melanoma model in vivo.
Topics: Animals; Apoptosis; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Caspases; Cell Line, Tumor; Cell Survival; DNA Fragmentation; Humans; Lung Neoplasms; Melanoma; Mice; Mice, Inbred C57BL; Multidrug Resistance-Associated Proteins; Neoplasm Metastasis; Neovascularization, Pathologic; Oleanolic Acid; Signal Transduction | 2011 |
Identification of unique sensitizing targets for anti-inflammatory CDDO-Me in metastatic melanoma by a large-scale synthetic lethal RNAi screening.
Topics: Anti-Inflammatory Agents; Apoptosis; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Genes, Neoplasm; High-Throughput Screening Assays; Humans; Melanoma; Neoplasm Metastasis; Oleanolic Acid; Reproducibility of Results; RNA Interference; RNA, Small Interfering; Signal Transduction; Skin Neoplasms; Treatment Outcome | 2013 |
Antitumor agents, 145. Cytotoxic asprellic acids A and C and asprellic acid B. new p-coumaroyl triterpenes, from Ilex asprella.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Coumaric Acids; Drug Screening Assays, Antitumor; Gastrointestinal Neoplasms; Humans; KB Cells; Leukemia P388; Melanoma; Mice; Oleanolic Acid; Plants, Medicinal; Tumor Cells, Cultured | 1993 |
Development of C-20 modified betulinic acid derivatives as antitumor agents.
Topics: Adenocarcinoma; Antineoplastic Agents; Betulinic Acid; Drug Screening Assays, Antitumor; Humans; Male; Melanoma; Oleanolic Acid; Pentacyclic Triterpenes; Prostatic Neoplasms; Structure-Activity Relationship; Triterpenes; Tumor Cells, Cultured | 2001 |