oleanolic acid has been researched along with Liver Diseases in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.17) | 18.7374 |
| 1990's | 8 (33.33) | 18.2507 |
| 2000's | 5 (20.83) | 29.6817 |
| 2010's | 8 (33.33) | 24.3611 |
| 2020's | 2 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Bian, J; Cai, G; Gu, J; Liu, Z; Shi, J; Wang, Y; Xu, W; Yuan, Y; Zou, H | 1 |
| Fu, X; Huang, J; Liao, S; Lu, Y; Wang, Y; Zhou, S | 1 |
| Huang, Y; Li, X; Liu, R; Lu, J; Luan, Y; Lv, L; Sun, R | 1 |
| Ardecky, RJ; Chung, TDY; Fung, X; Howard, BN; Huang, BQ; LaRusso, NF; Lee, PY; Lorenzo Pisarello, M; Masyuk, AI; Masyuk, TV; Pinkerton, AB; Sergienko, E | 1 |
| Chen, L; Chen, X; Kong, X; Wang, X; Wen, Y; Wu, H; Xia, Q; Xu, D; Yao, J; Yu, C | 1 |
| Ahmad, A; Ahmad, IZ; Tabassum, H | 1 |
| Kim, BM | 1 |
| Fan, Y; Hao, BB; Lu, L; Pan, XX; Qian, XF; Rao, JH; Wang, XH; Zhang, F | 1 |
| An, JH; Chung, KH; Kim, GJ; Lee, KJ; Song, DH; Yoo, HS | 1 |
| Fussenegger, M; Shao, J; Wang, Y; Xie, M; Xue, S; Yang, L; Ye, H; Yin, J; Yu, Y | 1 |
| Chao, JC; Chu, CC; Lin, YH; Tsai, YH; Wu, SJ | 1 |
| Buckley, DB; Klaassen, CD; Reisman, SA; Tanaka, Y | 1 |
| Jin, YY; Li, X; Zhang, Y | 1 |
| Chen, Y; Liu, J; Xu, H; Yang, X; Zhao, X | 1 |
| Abdel-Rahman, MM; Abdel-Zaher, AO; Hafez, MM; Omran, FM | 1 |
| Klaassen, CD; Liu, J; Liu, Y | 1 |
| Liu, GT; Shi, JZ | 1 |
| Bullock, P; Klaassen, CD; Liu, J; Liu, Y | 1 |
| Choudhuri, S; Klaassen, CD; Kreppel, H; Liu, J; Liu, Y | 1 |
| Klaassen, CD; Liu, J; Liu, Y; Madhu, C | 1 |
| Jeong, HG | 1 |
| Heath, TJ; Lamberton, JA; Pass, MA; Seawright, AA | 1 |
| Bhutani, KK; Pattabhi, V; Sharma, OP; Vaid, J | 1 |
| Chuang, CH; Lin, CC; Liu, SY; Yen, MH | 1 |
3 review(s) available for oleanolic acid and Liver Diseases
| Article | Year |
|---|---|
Nigella sativa L. and Its Bioactive Constituents as Hepatoprotectant: A Review.
Topics: Animals; Antioxidants; Benzoquinones; Humans; Lipid Peroxidation; Liver Diseases; Nigella sativa; Oleanolic Acid; Plant Extracts; Protective Agents; Reactive Oxygen Species; Saponins; Superoxide Dismutase | 2018 |
The Role of Saikosaponins in Therapeutic Strategies for Age-Related Diseases.
Topics: Apoptosis; Cardiovascular Diseases; Cell Cycle Checkpoints; Humans; Liver Diseases; Neoplasms; Neurodegenerative Diseases; Obesity; Oleanolic Acid; Oxidative Stress; Saponins | 2018 |
[Advances in mechanisms of saikosaponins in preventing and treating liver disease].
Topics: Humans; Liver Diseases; Oleanolic Acid; Phytotherapy; Saponins | 2009 |
21 other study(ies) available for oleanolic acid and Liver Diseases
| Article | Year |
|---|---|
Role of Nrf2 Nucleus Translocation in Beauvericin-Induced Cell Damage in Rat Hepatocytes.
Topics: Animals; Depsipeptides; Hepatocytes; Liver Diseases; NF-E2-Related Factor 2; Oleanolic Acid; Oxidative Stress; Rats | 2022 |
AMP-activated protein kinase-farnesoid X receptor pathway contributes to oleanolic acid-induced liver injury.
Topics: AMP-Activated Protein Kinases; Animals; Bile Acids and Salts; Carrier Proteins; Chemical and Drug Induced Liver Injury, Chronic; Cholestasis; Liver; Liver Diseases; Mice; Mice, Inbred C57BL; Oleanolic Acid | 2023 |
Saikosaponins induced hepatotoxicity in mice via lipid metabolism dysregulation and oxidative stress: a proteomic study.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bupleurum; Cholesterol; Cytochrome P-450 CYP2E1; Drugs, Chinese Herbal; Female; Hep G2 Cells; Humans; L-Lactate Dehydrogenase; Lipid Metabolism; Liver; Liver Diseases; Male; Mice; Nitric Oxide Synthase Type II; Oleanolic Acid; Oxidative Stress; Plant Roots; Proteomics; Saponins; Triglycerides | 2017 |
TGR5 contributes to hepatic cystogenesis in rodents with polycystic liver diseases through cyclic adenosine monophosphate/Gαs signaling.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Proliferation; Cyclic AMP; Cysts; Drug Evaluation, Preclinical; Drug Therapy, Combination; GTP-Binding Protein alpha Subunits, Gs; Humans; Liver Diseases; Mice; Oleanolic Acid; Polycystic Kidney Diseases; Primary Cell Culture; Pyrimidines; Rats; Receptors, G-Protein-Coupled; Somatostatin | 2017 |
The triterpenoid CDDO-imidazolide ameliorates mouse liver ischemia-reperfusion injury through activating the Nrf2/HO-1 pathway enhanced autophagy.
Topics: Animals; Autophagy; Blotting, Western; Cells, Cultured; DNA, Mitochondrial; Enzyme-Linked Immunosorbent Assay; Heme Oxygenase-1; Hepatocytes; Imidazoles; In Situ Nick-End Labeling; Liver; Liver Diseases; Male; Mice; Mice, Inbred C57BL; Microscopy, Electron, Transmission; NF-E2-Related Factor 2; Oleanolic Acid; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Signal Transduction | 2017 |
Oleanolic acid attenuates liver ischemia reperfusion injury by HO-1/Sesn2 signaling pathway.
Topics: Animals; Cytoprotection; Disease Models, Animal; Enzyme Inhibitors; Heme Oxygenase-1; Liver; Liver Diseases; Male; Membrane Proteins; Mice, Inbred C57BL; Nuclear Proteins; Oleanolic Acid; Peroxidases; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; Protoporphyrins; Reperfusion Injury; Signal Transduction; Time Factors | 2016 |
Hederagenin Supplementation Alleviates the Pro-Inflammatory and Apoptotic Response to Alcohol in Rats.
Topics: Alanine Transaminase; Alcohol Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Anti-Inflammatory Agents; Apoptosis; Aspartate Aminotransferases; bcl-2-Associated X Protein; Cholesterol; Cyclooxygenase 2; Dietary Supplements; Ethanol; Inflammation; Interleukin-6; Liver; Liver Diseases; Male; Oleanolic Acid; Phosphorylation; Rats; Rats, Wistar; RNA, Messenger; Signal Transduction; Triglycerides; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53 | 2017 |
A Synthetic-Biology-Inspired Therapeutic Strategy for Targeting and Treating Hepatogenous Diabetes.
Topics: Animals; Cell Engineering; Cell Line; Diabetes Mellitus, Type 2; Disease Models, Animal; Drug Design; Gene Expression Regulation; Gene Regulatory Networks; Genetic Engineering; Glucagon-Like Peptide 1; Humans; Insulin Resistance; Liver Diseases; Male; Mice; Mice, Transgenic; Oleanolic Acid; Synthetic Biology | 2017 |
Curcumin or saikosaponin a improves hepatic antioxidant capacity and protects against CCl4-induced liver injury in rats.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Curcumin; Glutathione; Lipids; Liver; Liver Diseases; Male; Oleanolic Acid; Rats; Rats, Sprague-Dawley; Saponins; Superoxide Dismutase | 2008 |
CDDO-Im protects from acetaminophen hepatotoxicity through induction of Nrf2-dependent genes.
Topics: Acetaminophen; Alanine Transaminase; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamate-Cysteine Ligase; Heme Oxygenase-1; Imidazoles; Liver; Liver Diseases; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; NAD(P)H Dehydrogenase (Quinone); NADPH Dehydrogenase; Necrosis; NF-E2-Related Factor 2; Nuclear Transfer Techniques; Oleanolic Acid; Response Elements; RNA, Messenger; Time Factors | 2009 |
Oleanolic acid nanosuspensions: preparation, in-vitro characterization and enhanced hepatoprotective effect.
Topics: Administration, Oral; Alanine Transaminase; Animals; Calorimetry, Differential Scanning; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chemistry, Pharmaceutical; China; Dosage Forms; Drug Evaluation, Preclinical; Hepatocytes; Injections, Subcutaneous; Liver Diseases; Malondialdehyde; Medicine, Chinese Traditional; Mice; Nanostructures; Oleanolic Acid; Particle Size; Solubility; Suspensions; Triterpenes; X-Ray Diffraction | 2005 |
Role of nitric oxide and reduced glutathione in the protective effects of aminoguanidine, gadolinium chloride and oleanolic acid against acetaminophen-induced hepatic and renal damage.
Topics: Acetaminophen; Administration, Oral; Alanine Transaminase; Alkaline Phosphatase; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Creatinine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gadolinium; Glutathione; Guanidines; Injections, Intramuscular; Kidney Diseases; Liver Diseases; Male; Nitric Oxide; Oleanolic Acid; Protective Agents; Rats; Rats, Wistar; Survival Analysis; Survival Rate | 2007 |
Protective effect of oleanolic acid against chemical-induced acute necrotic liver injury in mice.
Topics: Acetaminophen; Animals; Cadmium Poisoning; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Liver; Liver Diseases; Male; Mice; Necrosis; Oleanolic Acid | 1995 |
[Protective effect of the fulvotomentosides on paracetamol-induced hepatotoxicity in mice].
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Drugs, Chinese Herbal; Glutathione; Liver; Liver Diseases; Male; Mice; Oleanolic Acid; Saponins | 1995 |
Suppression of liver cytochrome P450 by alpha-hederin: relevance to hepatoprotection.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Antagonism; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Drugs, Chinese Herbal; Liver Diseases; Male; Methylation; Mice; Microsomes, Liver; Oleanolic Acid; Saponins | 1995 |
Oleanolic acid protects against cadmium hepatotoxicity by inducing metallothionein.
Topics: Alanine Transaminase; Animals; Blotting, Northern; Cadmium; Chemical and Drug Induced Liver Injury; Cytosol; Dose-Response Relationship, Drug; Isomerism; L-Iditol 2-Dehydrogenase; Liver; Liver Diseases; Male; Metallothionein; Mice; Mice, Inbred Strains; Oleanolic Acid; Organ Size; RNA Probes; RNA, Messenger; Subcellular Fractions; Tissue Distribution | 1993 |
Protective effects of oleanolic acid on acetaminophen-induced hepatotoxicity in mice.
Topics: Acetaminophen; Animals; Biliary Tract; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Glucuronosyltransferase; Glutathione; Liver; Liver Diseases; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; Oleanolic Acid; Subcellular Fractions; Uridine Diphosphate Glucuronic Acid | 1993 |
Inhibition of cytochrome P450 2E1 expression by oleanolic acid: hepatoprotective effects against carbon tetrachloride-induced hepatic injury.
Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutathione; Glutathione Transferase; L-Lactate Dehydrogenase; Liver; Liver Diseases; Male; Mice; Mice, Inbred BALB C; Microsomes, Liver; Oleanolic Acid | 1999 |
Lantadene A toxicity in sheep. A model for cholestasis.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cholestasis; Liver Diseases; Necrosis; Oleanolic Acid; Plant Extracts; Sheep; Sheep Diseases; Triterpenes | 1979 |
Biological action of lantadene C, a new hepatotoxicant from Lantana camara var. aculeata.
Topics: Acid Phosphatase; Animals; Bilirubin; Chemical and Drug Induced Liver Injury; Crystallization; Guinea Pigs; Liver; Liver Diseases; Male; Molecular Structure; Oleanolic Acid; Plant Extracts; Stereoisomerism; Toxins, Biological; X-Ray Diffraction | 1992 |
Evaluation of root quality of Bupleurum species by TLC scanner and the liver protective effects of "xiao-chai-hu-tang" prepared using three different Bupleurum species.
Topics: Animals; Calibration; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chromatography, Thin Layer; Drugs, Chinese Herbal; Liver; Liver Diseases; Male; Oleanolic Acid; Plant Extracts; Rats; Rats, Inbred Strains; Sapogenins; Saponins | 1991 |