Page last updated: 2024-08-21

oleanolic acid and Diabetes Mellitus

oleanolic acid has been researched along with Diabetes Mellitus in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (6.67)29.6817
2010's9 (60.00)24.3611
2020's5 (33.33)2.80

Authors

AuthorsStudies
Hong, D; Hu, LH; Li, J; Li, JY; Shen, Q; Shi, L; Zhang, W; Zhang, YN1
Chen, Y; Li, H; Qian, S; Wu, Y; Yang, S; Zhang, W1
Bu, Y; Chen, H; Chen, Q; Cheng, H; Feng, G; Kong, G; Lu, Z; Meng, M; Shi, T; Tian, Y; Yao, X1
Brandner, JM; Merfort, I; Schmidt, G; Templin, MF; Thomas, M; Wardecki, T; Werner, P1
Baumel-Alterzon, S; Biswal, S; Brill, G; Garcia-Ocaña, A; Jean-Pierre, C; Katz, LS; Li, Y; Scott, DK; Tse, I1
Leehey, DJ1
Cui, J; Liu, T; Shi, E; Wang, Y1
Farooq, MA; Kyunn, WW; Parveen, A1
Chu, DT; Ferdous, J; Hannan, MA; Hossain, KS; Islam, MN; Rahman, MM; Sarker, PP; Uddin, MJ1
Allard, PM; Ke, C; Tang, C; Wolfender, JL; Wolfrum, C; Ye, Y; Zhou, S1
Fukutomi, T; Kawamura, H; Pi, J; Sugawara, A; Takahashi, T; Uruno, A; Yagishita, Y; Yamamoto, M1
Chan, JY; Foster, CE; Hajighasemi-Ossareh, M; Ichii, H; Le, A; Li, S; Masuda, Y; Robles, L; Stamos, MJ; Vaziri, ND; Vo, K1
Li, S; Liu, C; Tang, Y; Zhang, Y1
de Haan, JB; Ritchie, RH; Rizky, L; Sharma, A; Stefanovic, N; Tate, M; Ward, KW1
Hsu, CC; Huang, CN; Wang, ZH; Yin, MC1

Reviews

2 review(s) available for oleanolic acid and Diabetes Mellitus

ArticleYear
Targeting Inflammation in Diabetic Kidney Disease: Is There a Role for Pentoxifylline?
    Kidney360, 2020, Apr-30, Volume: 1, Issue:4

    Topics: Animals; Diabetes Mellitus; Diabetic Nephropathies; Humans; Inflammation; Multicenter Studies as Topic; Oleanolic Acid; Pentoxifylline; Randomized Controlled Trials as Topic; Sodium-Glucose Transporter 2 Inhibitors

2020
Revisiting pharmacological potentials of Nigella sativa seed: A promising option for COVID-19 prevention and cure.
    Phytotherapy research : PTR, 2021, Volume: 35, Issue:3

    Topics: Benzoquinones; COVID-19 Drug Treatment; Diabetes Mellitus; Dietary Supplements; Humans; Nigella sativa; Oleanolic Acid; Pandemics; Plant Extracts; Saponins; Seeds

2021

Other Studies

13 other study(ies) available for oleanolic acid and Diabetes Mellitus

ArticleYear
Oleanolic acid and its derivatives: new inhibitor of protein tyrosine phosphatase 1B with cellular activities.
    Bioorganic & medicinal chemistry, 2008, Sep-15, Volume: 16, Issue:18

    Topics: Animals; Cell Line; CHO Cells; Cricetinae; Cricetulus; Diabetes Mellitus; Drugs, Chinese Herbal; Enzyme Inhibitors; Humans; Insulin; Obesity; Oleanolic Acid; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Receptor, Insulin; Structure-Activity Relationship; T-Lymphocytes

2008
Synthesis and biological evaluation of oleanolic acid derivatives as inhibitors of protein tyrosine phosphatase 1B.
    Journal of natural products, 2010, Nov-29, Volume: 73, Issue:11

    Topics: Diabetes Mellitus; Drugs, Chinese Herbal; Escherichia coli; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Obesity; Oleanolic Acid; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Structure-Activity Relationship

2010
A novel screening model for the molecular drug for diabetes and obesity based on tyrosine phosphatase Shp2.
    Bioorganic & medicinal chemistry letters, 2011, Jan-15, Volume: 21, Issue:2

    Topics: Animals; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Experimental; Drugs, Chinese Herbal; Forsythia; Humans; Hypoglycemic Agents; Mice; Obesity; Oleanolic Acid; Protein Tyrosine Phosphatase, Non-Receptor Type 11

2011
Influence of Birch Bark Triterpenes on Keratinocytes and Fibroblasts from Diabetic and Nondiabetic Donors.
    Journal of natural products, 2016, Apr-22, Volume: 79, Issue:4

    Topics: Betula; Cytokines; Diabetes Mellitus; Female; Fibroblasts; Humans; Interleukin-6; Interleukin-8; Keratinocytes; p38 Mitogen-Activated Protein Kinases; Pentacyclic Triterpenes; Plant Bark; rho GTP-Binding Proteins; Triterpenes; Wound Healing

2016
Nrf2 Regulates β-Cell Mass by Suppressing β-Cell Death and Promoting β-Cell Proliferation.
    Diabetes, 2022, 05-01, Volume: 71, Issue:5

    Topics: Animals; Apoptosis; Cell Proliferation; Diabetes Mellitus; Glucose; Insulin; Insulin-Secreting Cells; Mice; NF-E2-Related Factor 2; Oleanolic Acid

2022
Network pharmacology study of the mechanism underlying the therapeutic effect of Zhujing pill and its main component oleanolic acid against diabetic retinopathy.
    Bioscience reports, 2023, 01-31, Volume: 43, Issue:1

    Topics: Animals; Diabetes Mellitus; Diabetic Retinopathy; Drugs, Chinese Herbal; Molecular Docking Simulation; Network Pharmacology; Oleanolic Acid; Vascular Endothelial Growth Factor A

2023
A New Oleanane Type Saponin from the Aerial Parts of
    Molecules (Basel, Switzerland), 2020, May-06, Volume: 25, Issue:9

    Topics: Antioxidants; Benzothiazoles; Biphenyl Compounds; Chromatography, High Pressure Liquid; Diabetes Mellitus; Flavonoids; Glycoside Hydrolase Inhibitors; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Nigella sativa; Oleanolic Acid; Picrates; Plant Components, Aerial; Plant Extracts; Protein Tyrosine Phosphatases; Saponins; Sulfonic Acids; Triterpenes

2020
Identification of chemotypes in bitter melon by metabolomics: a plant with potential benefit for management of diabetes in traditional Chinese medicine.
    Metabolomics : Official journal of the Metabolomic Society, 2019, 07-18, Volume: 15, Issue:8

    Topics: Animals; China; Chromatography, High Pressure Liquid; Diabetes Mellitus; Drugs, Chinese Herbal; Glycosides; Humans; Mass Spectrometry; Medicine, Chinese Traditional; Metabolomics; Molecular Conformation; Momordica charantia; Oleanolic Acid; Triterpenes

2019
Nrf2 protects pancreatic β-cells from oxidative and nitrosative stress in diabetic model mice.
    Diabetes, 2014, Volume: 63, Issue:2

    Topics: Adaptor Proteins, Signal Transducing; Aging; Animals; Blood Glucose; Cytoskeletal Proteins; Diabetes Mellitus; Gene Expression Regulation; Imidazoles; Insulin; Insulin-Secreting Cells; Kelch-Like ECH-Associated Protein 1; Mice; Mice, Knockout; Mice, Transgenic; NF-E2-Related Factor 2; Nitric Oxide Synthase Type II; Oleanolic Acid; Oxidative Stress; Promoter Regions, Genetic; Rats

2014
Pharmacological activation of Nrf2 pathway improves pancreatic islet isolation and transplantation.
    Cell transplantation, 2015, Volume: 24, Issue:11

    Topics: Animals; Cell Survival; Diabetes Mellitus; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Mice; Mice, Nude; NF-E2-Related Factor 2; Oleanolic Acid; Oxidative Stress; Rats; Rats, Sprague-Dawley; Signal Transduction; Streptozocin

2015
Development of a method to screen and isolate potential α-glucosidase inhibitors from Panax japonicus C.A. Meyer by ultrafiltration, liquid chromatography, and counter-current chromatography.
    Journal of separation science, 2015, Volume: 38, Issue:12

    Topics: Acetonitriles; alpha-Glucosidases; Chromatography, Liquid; Diabetes Mellitus; Enzyme Inhibitors; Formates; Ginsenosides; Glycoside Hydrolase Inhibitors; Humans; Ligands; Mass Spectrometry; Methyl Ethers; Models, Theoretical; Multivariate Analysis; Oleanolic Acid; Panax; Plant Extracts; Saponins; Solvents; Spectrometry, Mass, Electrospray Ionization; Ultrafiltration

2015
The nuclear factor (erythroid-derived 2)-like 2 (Nrf2) activator dh404 protects against diabetes-induced endothelial dysfunction.
    Cardiovascular diabetology, 2017, 03-03, Volume: 16, Issue:1

    Topics: Animals; Aorta, Thoracic; Cells, Cultured; Diabetes Mellitus; Endothelium, Vascular; Humans; Male; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Oleanolic Acid; Organ Culture Techniques

2017
Anti-glycative effects of oleanolic acid and ursolic acid in kidney of diabetic mice.
    European journal of pharmacology, 2010, Feb-25, Volume: 628, Issue:1-3

    Topics: Aldehyde Reductase; Animals; Diabetes Mellitus; Gene Expression Regulation, Enzymologic; Glycation End Products, Advanced; Kidney; L-Iditol 2-Dehydrogenase; Lactoylglutathione Lyase; Male; Mice; Mice, Inbred BALB C; Oleanolic Acid; RNA, Messenger; Triterpenes; Ursolic Acid

2010