Page last updated: 2024-08-21

oleanolic acid and Degenerative Diseases, Central Nervous System

oleanolic acid has been researched along with Degenerative Diseases, Central Nervous System in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (8.33)29.6817
2010's8 (66.67)24.3611
2020's3 (25.00)2.80

Authors

AuthorsStudies
Du, J; Huang, X; Li, B; Li, L; Li, Y; Liu, J; Song, D1
Ai, Q; Chen, C; Shi, A; Wang, L; Wang, N; Wei, Y1
Arandarcikaite, O; Bendokas, V; Gudoityte, E; Liobikas, J; Mazeikiene, I1
Chen, Y; Xu, Y; Yang, H; Yu, L1
Chang, CH; Liao, VH; Wei, CC1
Kim, BM1
Beutler, JA; Cho, N; Hong, J; Kim, HW; Moon, EH; Sung, SH1
Cichewicz, RH; Du, L; Dunn, DE; He, DN; Kaltenbach, LS; Lo, DC; McCoy, DD; Newman, RA; Peng, J; Shah, B; Shen, L; Van Kanegan, MJ; Yang, P1
Law, BY; Liu, L; Lo, AC; Wong, VK; Wu, AG; Zeng, W; Zhu, YZ1
Kordower, JH; Masliah, E; McKay, H; Merrill, DA; Mufson, EJ; Roberts, JA; Tuszynski, MH1
Beal, MF; Calingasan, NY; Chaturvedi, RK; Kiaei, M; Liby, KT; Morrow, JD; Musiek, ES; Risingsong, R; Royce, D; Sporn, M; Thomas, B; Wille, EJ; Williams, C; Yang, L1
Beal, MF; Calingasan, NY; Damiano, M; Kiaei, M; Liby, KT; Naseri, N; Neymotin, A; Petri, S; Risingsong, R; Sporn, M; Wille, E1

Reviews

3 review(s) available for oleanolic acid and Degenerative Diseases, Central Nervous System

ArticleYear
Oleanolic acid and ursolic acid: therapeutic potential in neurodegenerative diseases, neuropsychiatric diseases and other brain disorders.
    Nutritional neuroscience, 2023, Volume: 26, Issue:5

    Topics: Brain Diseases; Humans; Neurodegenerative Diseases; Oleanolic Acid; Quality of Life; Triterpenes; Ursolic Acid

2023
Ursolic and Oleanolic Acids: Plant Metabolites with Neuroprotective Potential.
    International journal of molecular sciences, 2021, Apr-27, Volume: 22, Issue:9

    Topics: Animals; Drug Development; Humans; Neurodegenerative Diseases; Neuroprotective Agents; Oleanolic Acid; Plant Extracts; Triterpenes; Ursolic Acid

2021
The Role of Saikosaponins in Therapeutic Strategies for Age-Related Diseases.
    Oxidative medicine and cellular longevity, 2018, Volume: 2018

    Topics: Apoptosis; Cardiovascular Diseases; Cell Cycle Checkpoints; Humans; Liver Diseases; Neoplasms; Neurodegenerative Diseases; Obesity; Oleanolic Acid; Oxidative Stress; Saponins

2018

Other Studies

9 other study(ies) available for oleanolic acid and Degenerative Diseases, Central Nervous System

ArticleYear
Saikosaponin-D Mitigates Oxidation in SH-SY5Y Cells Stimulated by Glutamate Through Activation of Nrf2 Pathway: Involvement of PI3K.
    Neurotoxicity research, 2022, Volume: 40, Issue:1

    Topics: Apoptosis; Cell Line, Tumor; Glutamic Acid; Heme Oxygenase-1; Humans; Malondialdehyde; Neurodegenerative Diseases; Neuroprotective Agents; NF-E2-Related Factor 2; Oleanolic Acid; Oxidative Stress; Phosphatidylinositol 3-Kinases; Reactive Oxygen Species; Saponins; Signal Transduction

2022
Esculentoside A exerts anti-inflammatory activity in microglial cells.
    International immunopharmacology, 2017, Volume: 51

    Topics: Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents; Apoptosis; Cell Line; Dinoprostone; Humans; Lipopolysaccharides; Microglia; Neurodegenerative Diseases; Neurogenic Inflammation; NF-kappa B; Nitric Oxide; NLR Family, Pyrin Domain-Containing 3 Protein; Oleanolic Acid; Phytolaccaceae; Rats; Saponins; Signal Transduction

2017
Anti-Parkinsonian effects of β-amyrin are regulated via LGG-1 involved autophagy pathway in Caenorhabditis elegans.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2017, Dec-01, Volume: 36

    Topics: alpha-Synuclein; Animals; Animals, Genetically Modified; Antioxidants; Antiparkinson Agents; Autophagy; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Disease Models, Animal; Dopaminergic Neurons; Microtubule-Associated Proteins; Neurodegenerative Diseases; Oleanolic Acid; Oxidative Stress; Parkinson Disease

2017
Inhibition of Nitric Oxide Production in BV2 Microglial Cells by Triterpenes from Tetrapanax papyriferus.
    Molecules (Basel, Switzerland), 2016, Apr-07, Volume: 21, Issue:4

    Topics: Anti-Inflammatory Agents; Araliaceae; Cyclooxygenase 2; Cytokines; Gene Expression Regulation; Humans; Inflammation; Lipopolysaccharides; Microglia; Neurodegenerative Diseases; Nitric Oxide; Oleanolic Acid; Plant Extracts; Plant Leaves; Plants, Medicinal

2016
Dual activities of the anti-cancer drug candidate PBI-05204 provide neuroprotection in brain slice models for neurodegenerative diseases and stroke.
    Scientific reports, 2016, 05-12, Volume: 6

    Topics: Animals; Antineoplastic Agents; Brain; Chemical Fractionation; Disease Models, Animal; Female; Glucose; Heterocyclic Compounds, 4 or More Rings; Humans; Male; Nerium; Neurodegenerative Diseases; Neuroprotective Agents; Oleanolic Acid; Organ Culture Techniques; Oxygen; Plant Extracts; Rats, Sprague-Dawley; Stroke

2016
Hederagenin and α-hederin promote degradation of proteins in neurodegenerative diseases and improve motor deficits in MPTP-mice.
    Pharmacological research, 2017, Volume: 115

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adenylate Kinase; alpha-Synuclein; Animals; Autophagy; Cell Line, Tumor; Disease Models, Animal; Drugs, Chinese Herbal; Female; Hedera; Huntingtin Protein; Male; Mice; Mice, Inbred C57BL; Neurodegenerative Diseases; Oleanolic Acid; PC12 Cells; Rats; Saponins; TOR Serine-Threonine Kinases

2017
Association of early experience with neurodegeneration in aged primates.
    Neurobiology of aging, 2011, Volume: 32, Issue:1

    Topics: Aging; Animals; Disease Models, Animal; Environment; Macaca mulatta; Neocortex; Neurodegenerative Diseases; Oleanolic Acid; Synaptophysin

2011
Neuroprotective effects of the triterpenoid, CDDO methyl amide, a potent inducer of Nrf2-mediated transcription.
    PloS one, 2009, Jun-01, Volume: 4, Issue:6

    Topics: Animals; Antioxidants; Cell Line, Tumor; Humans; Male; Mice; Mice, Inbred C57BL; Models, Biological; Neurodegenerative Diseases; NF-E2-Related Factor 2; Oleanolic Acid; Rats; Rats, Inbred Lew; Terpenes; Transcription, Genetic

2009
Neuroprotective effect of Nrf2/ARE activators, CDDO ethylamide and CDDO trifluoroethylamide, in a mouse model of amyotrophic lateral sclerosis.
    Free radical biology & medicine, 2011, Jul-01, Volume: 51, Issue:1

    Topics: Amyotrophic Lateral Sclerosis; Animals; Cell Line; Cell Nucleus; Disease Models, Animal; Inflammation; Major Histocompatibility Complex; Mice; Mice, Transgenic; Mitochondria; Neurodegenerative Diseases; NF-E2-Related Factor 2; Oleanolic Acid; Oxidative Stress; Proteins; RNA, Messenger; Signal Transduction; Superoxide Dismutase; Vesicular Transport Proteins

2011