oleanolic acid has been researched along with Colorectal Cancer in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 10 (71.43) | 24.3611 |
| 2020's | 2 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, L; Liu, M; Meng, X; Ming, T; Ren, S; Sun, Q; Tang, S; Tao, Q; Xu, H; Yang, H; Zeng, S; Zhao, H | 1 |
| Li, H; Lin, J; Liu, H; Liu, X; Mao, Q; Min, J; Wu, M; Zeng, R; Zhang, C; Zheng, A | 1 |
| Niu, G; Pei, Y; Sun, L; Wang, D | 1 |
| Cui, W; Fan, X; Li, D; Rao, J; Shen, Q; Tou, F; Wang, H; Zhang, J; Zhang, Z; Zheng, Z | 1 |
| Sha, L; Sui, Y; Wang, L; Wang, X; Yun, L; Zhang, H | 1 |
| Cai, G; Feng, Y; Huang, Y; Ji, Q; Li, Q; Shi, L; Sun, J; Wang, Y; Zhang, J | 1 |
| Chu, J; Li, L; Lin, J; Peng, J; Shen, A; Wei, L | 1 |
| Bozeman, RG; Kaisani, A; Kim, SB; Kim, W; Richardson, JA; Shay, JW; Wright, WE; Zhang, L | 1 |
| Li, L; Lin, J; Peng, J; Shen, A; Sun, G; Wei, L; Zhang, M | 1 |
| Arbab, AS; Deeb, D; Dulchavsky, SA; Gao, X; Gautam, SC; Hao, J; Liu, Y | 1 |
| Arbab-Ali, S; Deeb, D; Dulchavsky, SA; Gao, X; Gautam, SC; Liu, P; Liu, Y | 1 |
| Andreeff, M; Dezube, BJ; Eder, JP; Ferguson, DA; He, X; Hong, DS; Konoplev, S; Konopleva, M; Kufe, D; Kurzrock, R; Lawrence, D; Lazarus, H; Meyer, CJ; Mier, J; Naing, A; Shapiro, GI; Supko, JG; Wheler, J | 1 |
| Chen, YX; Liu, XL; Qian, BC; Sun, HX; Zheng, XL | 1 |
| Mao, JS; Pan, YJ; Wang, KW; Zheng, S | 1 |
1 trial(s) available for oleanolic acid and Colorectal Cancer
| Article | Year |
|---|---|
A phase I first-in-human trial of bardoxolone methyl in patients with advanced solid tumors and lymphomas.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Colorectal Neoplasms; Cyclin D1; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Janus Kinases; Kidney Neoplasms; Lymphoma; Male; Maximum Tolerated Dose; Melanoma; Middle Aged; NAD(P)H Dehydrogenase (Quinone); Neoplasms; NF-E2-Related Factor 2; NF-kappa B; Oleanolic Acid; RNA, Messenger; STAT Transcription Factors; Thyroid Neoplasms; Young Adult | 2012 |
13 other study(ies) available for oleanolic acid and Colorectal Cancer
| Article | Year |
|---|---|
Ursolic acid inhibits the activation of smoothened-independent non-canonical hedgehog pathway in colorectal cancer by suppressing AKT signaling cascade.
Topics: Animals; Cell Proliferation; Colorectal Neoplasms; Hedgehog Proteins; Humans; Oleanolic Acid; Proto-Oncogene Proteins c-akt; Signal Transduction; Triterpenes; Ursolic Acid; Zinc Finger Protein GLI1 | 2022 |
Self-assembled traditional Chinese nanomedicine modulating tumor immunosuppressive microenvironment for colorectal cancer immunotherapy.
Topics: Carcinogens; China; Colorectal Neoplasms; Humans; Immunologic Factors; Immunotherapy; Lentinan; Nanomedicine; Oleanolic Acid; Tumor Microenvironment; Ursolic Acid | 2022 |
Oleanolic Acid Inhibits Colorectal Cancer Angiogenesis by Blocking the VEGFR2 Signaling Pathway.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Human Umbilical Vein Endothelial Cells; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Neovascularization, Pathologic; Oleanolic Acid; Signal Transduction; Structure-Activity Relationship; Vascular Endothelial Growth Factor Receptor-2; Wound Healing | 2018 |
Macranthoidin B Modulates Key Metabolic Pathways to Enhance ROS Generation and Induce Cytotoxicity and Apoptosis in Colorectal Cancer.
Topics: Amino Acids; Animals; Apoptosis; Carbohydrate Metabolism; Caspase 3; Chromatography, High Pressure Liquid; Colorectal Neoplasms; Discriminant Analysis; Gas Chromatography-Mass Spectrometry; Glutathione Peroxidase; HCT116 Cells; Humans; Least-Squares Analysis; Lipid Metabolism; Mass Spectrometry; Metabolome; Metabolomics; Mice; Mice, Nude; Oleanolic Acid; Reactive Oxygen Species; S-Adenosylhomocysteine; Saponins; Superoxide Dismutase; Transplantation, Heterologous | 2018 |
Endoplasmic reticulum stress triggered by Soyasapogenol B promotes apoptosis and autophagy in colorectal cancer.
Topics: Animals; Apoptosis; Autophagy; Cell Proliferation; Colorectal Neoplasms; Endoplasmic Reticulum Stress; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Oleanolic Acid; Saponins; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2019 |
α-hederin induces autophagic cell death in colorectal cancer cells through reactive oxygen species dependent AMPK/mTOR signaling pathway activation.
Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colorectal Neoplasms; HCT116 Cells; Humans; Male; Mice; Neoplasm Transplantation; Oleanolic Acid; Reactive Oxygen Species; Saponins; Signal Transduction; TOR Serine-Threonine Kinases | 2019 |
Oleanolic acid modulates multiple intracellular targets to inhibit colorectal cancer growth.
Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Cycle; Cell Proliferation; Colorectal Neoplasms; HT29 Cells; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Oleanolic Acid; Xenograft Model Antitumor Assays | 2015 |
Radiation promotes colorectal cancer initiation and progression by inducing senescence-associated inflammatory responses.
Topics: Adenomatous Polyposis Coli; Aging; Animals; Colorectal Neoplasms; Disease Models, Animal; Disease Progression; DNA Damage; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Mice, Inbred C57BL; Mice, Knockout; Mutation; Oleanolic Acid; Oxidative Stress; Proton Therapy; Reverse Transcriptase Polymerase Chain Reaction; Survival Analysis; Tumor Suppressor Protein p53; Whole-Body Irradiation | 2016 |
Oleanolic acid inhibits colorectal cancer angiogenesis in vivo and in vitro via suppression of STAT3 and Hedgehog pathways.
Topics: Animals; Cell Line, Tumor; Colorectal Neoplasms; Hedgehog Proteins; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Proteins; Neovascularization, Pathologic; Oleanolic Acid; Signal Transduction; STAT3 Transcription Factor | 2016 |
Synthetic triterpenoids inhibit growth, induce apoptosis and suppress pro-survival Akt, mTOR and NF-{kappa}B signaling proteins in colorectal cancer cells.
Topics: Apoptosis; bcl-Associated Death Protein; bcl-X Protein; Caspases; Colorectal Neoplasms; Enzyme Activation; HCT116 Cells; HT29 Cells; Humans; Imidazoles; Inhibitor of Apoptosis Proteins; Intracellular Signaling Peptides and Proteins; Microtubule-Associated Proteins; NF-kappa B; Oleanolic Acid; Oncogene Protein v-akt; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Survivin; TOR Serine-Threonine Kinases; Triterpenes | 2010 |
Role of reactive oxygen species (ROS) in CDDO-Me-mediated growth inhibition and apoptosis in colorectal cancer cells.
Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Apoptosis; Cell Line, Tumor; Colorectal Neoplasms; Free Radicals; Humans; Oleanolic Acid; Reactive Oxygen Species | 2011 |
Astilbic acid induced COLO 205 cell apoptosis by regulating Bcl-2 and Bax expression and activating caspase-3.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase Inhibitors; Caspases; Cell Division; Cell Line, Tumor; Colorectal Neoplasms; DNA Fragmentation; Humans; Molecular Structure; Oleanolic Acid; Oligopeptides; Plants, Medicinal; Proto-Oncogene Proteins c-bcl-2; Rhizome; Saxifragaceae | 2004 |
[Antitumor effects of novel triterpene from Celastrus hypoleucus on human colorectal cancer cell line RKO in vitro].
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Celastrus; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Oleanolic Acid; Plant Stems; Plants, Medicinal | 2006 |