Page last updated: 2024-08-21

oleanolic acid and Cholestasis

oleanolic acid has been researched along with Cholestasis in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19903 (23.08)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (38.46)24.3611
2020's5 (38.46)2.80

Authors

AuthorsStudies
Feng, H; Hu, Y; Lu, Y; Zhou, S1
Huang, C; Liu, F; Liu, J; Meng, C; Xia, C1
Gu, Q; Huang, C; Liu, F; Liu, J; Meng, C; Xia, C1
Fu, X; Huang, J; Liao, S; Lu, Y; Wang, Y; Zhou, S1
Aljubiri, SM; Alrefaei, AF; El Hamd, MA; El-Maghrabey, MH; Fujita, M; Kadasah, SF; Otsuka, M; Radwan, MO; Tateishi, H1
Liu, J; Lu, YF; Wan, XL; Xu, Y1
Fan, F; Klaassen, CD; Liu, J; Lu, YF; Wu, KC; Zhang, Y1
Bi, H; Chen, P; Deng, R; Fan, X; Huang, M; Wang, Y; Xu, C; Zeng, H; Zhou, X1
Bi, H; Chen, P; Deng, R; Fan, X; Huang, M; Li, D; Li, J; Zeng, H1
Arora, S; Blomenkamp, K; Buchanan, PM; Guzman, MA; Jain, AK; Jun, IC; Long, J; Luong, R; Mittal, A; Neuschwander-Tetri, BA; Sharma, A; Teckman, J; Westrich, DJ1
Findlay, L; Pass, MA; Pugh, MW1
Heath, TJ; Lamberton, JA; Pass, MA; Seawright, AA1
Bullock, G; Eakins, MN; Sawyer, BC; Slater, TF1

Reviews

1 review(s) available for oleanolic acid and Cholestasis

ArticleYear
Harnessing Oleanolic Acid and Its Derivatives as Modulators of Metabolic Nuclear Receptors.
    Biomolecules, 2023, 09-28, Volume: 13, Issue:10

    Topics: Animals; Cholestasis; Liver; Mice; Oleanolic Acid; Rabbits; Receptors, Cytoplasmic and Nuclear; Transcription Factors

2023

Other Studies

12 other study(ies) available for oleanolic acid and Cholestasis

ArticleYear
Farnesoid X receptor contributes to oleanolic acid-induced cholestatic liver injury in mice.
    Journal of applied toxicology : JAT, 2022, Volume: 42, Issue:8

    Topics: Animals; Bile Acids and Salts; Cholestasis; Chromatography, Liquid; Liver; Mice; Mice, Inbred C57BL; Oleanolic Acid; Tandem Mass Spectrometry

2022
Oleanolic acid alleviates ANIT-induced cholestatic liver injury by activating Fxr and Nrf2 pathways to ameliorate disordered bile acids homeostasis.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2022, Jul-20, Volume: 102

    Topics: 1-Naphthylisothiocyanate; Animals; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Cholestasis; Homeostasis; Liver; NF-E2-Related Factor 2; Oleanolic Acid; Rats; Receptors, Cytoplasmic and Nuclear; Tandem Mass Spectrometry

2022
NRF2 and FXR dual signaling pathways cooperatively regulate the effects of oleanolic acid on cholestatic liver injury.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2023, Volume: 108

    Topics: Animals; beta Catenin; Bile Acids and Salts; Cholestasis; Liver; NF-E2-Related Factor 2; Oleanolic Acid; Rats; Receptors, Cytoplasmic and Nuclear; Signal Transduction

2023
AMP-activated protein kinase-farnesoid X receptor pathway contributes to oleanolic acid-induced liver injury.
    Journal of applied toxicology : JAT, 2023, Volume: 43, Issue:8

    Topics: AMP-Activated Protein Kinases; Animals; Bile Acids and Salts; Carrier Proteins; Chemical and Drug Induced Liver Injury, Chronic; Cholestasis; Liver; Liver Diseases; Mice; Mice, Inbred C57BL; Oleanolic Acid

2023
Repeated oral administration of oleanolic acid produces cholestatic liver injury in mice.
    Molecules (Basel, Switzerland), 2013, Mar-07, Volume: 18, Issue:3

    Topics: Acute-Phase Proteins; Administration, Oral; Animals; Bile Acids and Salts; Biomarkers; Body Weight; Cholestasis; Dose-Response Relationship, Drug; Gene Expression Regulation; Inflammation; Liver; Male; Mice; Oleanolic Acid; Organ Size; Organic Anion Transport Protein 1

2013
Oleanolic acid alters bile acid metabolism and produces cholestatic liver injury in mice.
    Toxicology and applied pharmacology, 2013, Nov-01, Volume: 272, Issue:3

    Topics: Animals; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Cholestasis; Dose-Response Relationship, Drug; Female; Mice; Mice, Inbred C57BL; Oleanolic Acid

2013
Low dose of oleanolic acid protects against lithocholic acid-induced cholestasis in mice: potential involvement of nuclear factor-E2-related factor 2-mediated upregulation of multidrug resistance-associated proteins.
    Drug metabolism and disposition: the biological fate of chemicals, 2014, Volume: 42, Issue:5

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cholestasis; Dose-Response Relationship, Drug; Gene Expression; Hep G2 Cells; Hepatocytes; Humans; Lithocholic Acid; Liver Function Tests; Male; Mice; Mice, Inbred C57BL; Multidrug Resistance-Associated Proteins; NF-E2-Related Factor 2; Oleanolic Acid; Primary Cell Culture; Up-Regulation

2014
Oleanolic acid attenuates obstructive cholestasis in bile duct-ligated mice, possibly via activation of NRF2-MRPs and FXR antagonism.
    European journal of pharmacology, 2015, Oct-15, Volume: 765

    Topics: Animals; Cells, Cultured; Cholestasis; Dose-Response Relationship, Drug; Hepatocytes; Ligation; Male; Mice; Mice, Inbred C57BL; Multidrug Resistance-Associated Proteins; NF-E2-Related Factor 2; Oleanolic Acid; Receptors, Cytoplasmic and Nuclear

2015
Preserved Gut Microbial Diversity Accompanies Upregulation of TGR5 and Hepatobiliary Transporters in Bile Acid-Treated Animals Receiving Parenteral Nutrition.
    JPEN. Journal of parenteral and enteral nutrition, 2017, Volume: 41, Issue:2

    Topics: Animals; Animals, Newborn; ATP Binding Cassette Transporter, Subfamily B, Member 11; Atrophy; Bacteroides; Bile Acids and Salts; Cholestasis; Gastrointestinal Microbiome; Intestinal Diseases; Intestinal Mucosa; Intestines; Oleanolic Acid; Parenteral Nutrition; Receptors, G-Protein-Coupled; Sus scrofa; Up-Regulation

2017
Studies on the mechanism of toxicity of reduced lantadene A in rats.
    Biochemical pharmacology, 1981, Jun-15, Volume: 30, Issue:12

    Topics: Adenosine Triphosphatases; Animals; Bile Canaliculi; Cholestasis; Enzyme Induction; Enzyme Inhibitors; Female; Liver; Male; Nucleotidases; Oleanolic Acid; Rats; Spironolactone; Triterpenes

1981
Lantadene A toxicity in sheep. A model for cholestasis.
    Pathology, 1979, Volume: 11, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cholestasis; Liver Diseases; Necrosis; Oleanolic Acid; Plant Extracts; Sheep; Sheep Diseases; Triterpenes

1979
Studies on bile secretion with the aid of the isolated perfused rat liver. I. Inhibitory action of sporidesmin and icterogenin.
    Proceedings of the Royal Society of London. Series B, Biological sciences, 1974, Jul-30, Volume: 186, Issue:1085

    Topics: Animals; Bile; Bile Ducts, Intrahepatic; Carboxylic Acids; Cholestasis; Female; Indoles; Liver; Mycotoxins; Oleanolic Acid; Perfusion; Pyrazines; Pyrroles; Rats; Secretory Rate; Triterpenes

1974