oleanolic acid has been researched along with Carcinoma, Non-Small Cell Lung in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (37.50) | 29.6817 |
| 2010's | 7 (43.75) | 24.3611 |
| 2020's | 3 (18.75) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Z; Cheng, YY; Duan, HQ; Goto, M; Huang, KY; Lee, KH; Ling, Y; Liu, YL; Morris-Natschke, SL; Tong, XH; Yang, PC; Yang, SL | 1 |
| Ding, D; Gai, C; Li, W; Li, Z; Lv, S; Wang, Y; Yu, M; Zhang, W; Zheng, J | 1 |
| Ai, Y; Du, K; Jiang, X; Kang, F; Liu, W; Luo, Y; Ren, C; Wang, L; Xu, Y; Zhang, Y; Zhu, B; Zhu, H | 1 |
| Chan, E; Cino, EA; Di Guglielmo, GM; Soares, IN; Thai, B; Trelford, CB; Viana, R | 1 |
| Chen, W; Liu, K; Ren, F; Wu, H; Wu, S; Xu, F; Zheng, D | 1 |
| Ahsan, A; Chu, P; Gao, L; Kong, L; Lin, Y; Ma, X; Peng, J; Qaed, E; Song, Y; Sun, B; Tang, Z; Wang, S; Zhang, J | 1 |
| Chen, B; Du, B; Gong, Q; Ho, HI; Li, Q; Liu, X; Lu, Y; Tan, Y; Wang, K; Wu, W; Xiao, J; Yin, T; Zhan, Y; Zhang, F; Zhang, Y; Zou, Y | 1 |
| Chen, J; Feng, Y; Gu, L; Guo, J; Jiang, H; Li, Y; Liao, S; Ma, L; Sun, M; Wang, H; Wen, H; Yu, X; Zeng, B; Zhou, Y | 1 |
| Khuri, FR; Sun, SY; Yue, P; Zou, W | 1 |
| Lee, JH; Min, BS; Ryoo, S; Seo, J; Tae, N | 1 |
| Fernandes, J; Gattass, CR; Lúcio, KA; Monção-Ribeiro, LC; Rocha, Gda G; Takiya, CM | 1 |
| Gribble, GW; Honda, T; Hong, WK; Kim, KB; Lotan, R; Sporn, MB; Suh, N; Sun, SY; Wu, GS; Yue, P | 1 |
| Hsu, YL; Kuo, PL; Lin, CC | 1 |
| Khuri, FR; Liu, X; Lotan, R; Sporn, MB; Sun, SY; Yue, P; Zhou, Z; Zou, W | 1 |
| Khuri, FR; Sun, SY; Yue, P; Zhou, Z | 1 |
| Chen, S; Khuri, FR; Liu, X; Sporn, MB; Sun, SY; Yue, P; Zou, W | 1 |
16 other study(ies) available for oleanolic acid and Carcinoma, Non-Small Cell Lung
| Article | Year |
|---|---|
Discovery of an Oleanolic Acid/Hederagenin-Nitric Oxide Donor Hybrid as an EGFR Tyrosine Kinase Inhibitor for Non-Small-Cell Lung Cancer.
Topics: A549 Cells; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Drug Design; Drug Resistance, Neoplasm; ErbB Receptors; Gefitinib; Humans; Lung Neoplasms; Mutation; Nitric Oxide; Nitric Oxide Donors; Oleanolic Acid; Protein Kinase Inhibitors | 2019 |
Acetaminophen sensitizing erastin-induced ferroptosis via modulation of Nrf2/heme oxygenase-1 signaling pathway in non-small-cell lung cancer.
Topics: Acetaminophen; Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Drug Synergism; Ferroptosis; Gene Expression Regulation, Neoplastic; Heme Oxygenase-1; Humans; Lipid Peroxides; Malondialdehyde; Mice; NF-E2-Related Factor 2; Oleanolic Acid; Piperazines; Signal Transduction; Xenograft Model Antitumor Assays | 2020 |
Olean-28,13b-olide 2 plays a role in cisplatin-mediated apoptosis and reverses cisplatin resistance in human lung cancer through multiple signaling pathways.
Topics: A549 Cells; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cisplatin; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; Humans; Lung Neoplasms; Oleanolic Acid; Reactive Oxygen Species; Signal Transduction | 2019 |
The synthetic oleanane triterpenoid CDDO-Me binds and inhibits pyruvate kinase M2.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Glucose; Humans; Hypoxia; Oleanolic Acid; Pyruvate Kinase | 2020 |
Saikosaponin D inhibits proliferation and induces apoptosis of non-small cell lung cancer cells by inhibiting the STAT3 pathway.
Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Humans; Lung Neoplasms; Oleanolic Acid; Saponins; STAT3 Transcription Factor | 2020 |
Induction of autophagy by an oleanolic acid derivative, SZC017, promotes ROS-dependent apoptosis through Akt and JAK2/STAT3 signaling pathway in human lung cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Autophagy; Beclin-1; Carcinoma, Non-Small-Cell Lung; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cell Survival; Humans; Janus Kinase 2; Lung Neoplasms; Oleanolic Acid; Phosphorylation; Piperidines; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; STAT3 Transcription Factor | 2017 |
The Novel Autophagy Inhibitor Alpha-Hederin Promoted Paclitaxel Cytotoxicity by Increasing Reactive Oxygen Species Accumulation in Non-Small Cell Lung Cancer Cells.
Topics: Apoptosis; Autophagosomes; Autophagy; Carcinoma, Non-Small-Cell Lung; Cathepsins; Cell Line, Tumor; Cell Proliferation; Humans; Hydrogen-Ion Concentration; Lung Neoplasms; Lysosomes; Oleanolic Acid; Paclitaxel; Reactive Oxygen Species; Saponins; Tubulin Modulators | 2018 |
3-O-(Z)-coumaroyloleanolic acid overcomes Cks1b-induced chemoresistance in lung cancer by inhibiting Hsp90 and MEK pathways.
Topics: Adult; Aged; Animals; Antineoplastic Agents; Benzodioxoles; Carcinoma, Non-Small-Cell Lung; CDC2-CDC28 Kinases; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Follow-Up Studies; HSP90 Heat-Shock Proteins; Humans; Lung Neoplasms; Male; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Mice; Mice, Nude; Middle Aged; Oleanolic Acid; Purines; Retrospective Studies; Tumor Burden; Tumor Cells, Cultured | 2017 |
Coupling of endoplasmic reticulum stress to CDDO-Me-induced up-regulation of death receptor 5 via a CHOP-dependent mechanism involving JNK activation.
Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Endoplasmic Reticulum; Enzyme Activation; Glutathione; Humans; Lung Neoplasms; MAP Kinase Kinase 4; Oleanolic Acid; Receptors, TNF-Related Apoptosis-Inducing Ligand; Transcription Factor CHOP; Transcription, Genetic; Up-Regulation | 2008 |
3-Oxoolean-12-en-27-oic acid inhibits the proliferation of non-small cell lung carcinoma cells by inducing cell-cycle arrest at G0/G1 phase.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Growth Processes; Cell Line, Tumor; Cyclin D1; Cyclin E; Down-Regulation; G1 Phase; Humans; Lung Neoplasms; Oleanolic Acid; Resting Phase, Cell Cycle; Retinoblastoma Protein | 2011 |
Oleanolic acid initiates apoptosis in non-small cell lung cancer cell lines and reduces metastasis of a B16F10 melanoma model in vivo.
Topics: Animals; Apoptosis; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Caspases; Cell Line, Tumor; Cell Survival; DNA Fragmentation; Humans; Lung Neoplasms; Melanoma; Mice; Mice, Inbred C57BL; Multidrug Resistance-Associated Proteins; Neoplasm Metastasis; Neovascularization, Pathologic; Oleanolic Acid; Signal Transduction | 2011 |
Identification of a novel synthetic triterpenoid, methyl-2-cyano-3,12-dioxooleana-1,9-dien-28-oate, that potently induces caspase-mediated apoptosis in human lung cancer cells.
Topics: Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Caspase Inhibitors; Caspases; Cell Differentiation; Cell Division; Cytochrome c Group; Enzyme Activation; Enzyme Inhibitors; Humans; Lung Neoplasms; Mitochondria; Oleanolic Acid; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured | 2002 |
The proliferative inhibition and apoptotic mechanism of Saikosaponin D in human non-small cell lung cancer A549 cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Division; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA, Neoplasm; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Fas Ligand Protein; fas Receptor; Flow Cytometry; Humans; Lung Neoplasms; Medicine, Chinese Traditional; Membrane Glycoproteins; Oleanolic Acid; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Reagent Kits, Diagnostic; Saponins; Tumor Suppressor Protein p53 | 2004 |
c-Jun NH2-terminal kinase-mediated up-regulation of death receptor 5 contributes to induction of apoptosis by the novel synthetic triterpenoid methyl-2-cyano-3,12-dioxooleana-1, 9-dien-28-oate in human lung cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, Non-Small-Cell Lung; Caspase 8; Caspases; Cell Line, Tumor; Drug Synergism; Enzyme Activation; Humans; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; Membrane Glycoproteins; Oleanolic Acid; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Signal Transduction; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha; Up-Regulation | 2004 |
Depletion of intracellular glutathione contributes to JNK-mediated death receptor 5 upregulation and apoptosis induction by the novel synthetic triterpenoid methyl-2-cyano-3, 12-dioxooleana-1, 9-dien-28-oate (CDDO-Me).
Topics: Antioxidants; Apoptosis; Blotting, Northern; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Glutathione; Humans; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; Oleanolic Acid; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Receptors, TNF-Related Apoptosis-Inducing Ligand; Up-Regulation | 2006 |
c-FLIP downregulation contributes to apoptosis induction by the novel synthetic triterpenoid methyl-2-cyano-3, 12-dioxooleana-1, 9-dien-28-oate (CDDO-Me) in human lung cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; CASP8 and FADD-Like Apoptosis Regulating Protein; Cell Line, Tumor; Down-Regulation; Humans; Lung Neoplasms; MAP Kinase Kinase 4; Oleanolic Acid; Proteasome Endopeptidase Complex; Terpenes; TNF-Related Apoptosis-Inducing Ligand; Ubiquitin | 2007 |